4JKPG

Restricting hiv-1 pathways for escape using rationally-designed anti-hiv-1 antibodies
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
353
structure length
340
Chain Sequence
VWKDADTTLFCASDAKAHETECHNVWATHACVPTDPNPQEIHLENVTENFNMWKNNMVEQMQEDVISLWDQCLQPCVKLTGGSVIKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNDIRKAYCEINGTKWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHHFNCRGEFFYCNTTQLFNNTCIGCNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies.
pubmed doi rcsb
molecule tags Viral protein/immune system
source organism Human immunodeficiency virus 1
molecule keywords gp120
total genus 90
structure length 340
sequence length 353
ec nomenclature
pdb deposition date 2013-03-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 4jkpG01
4OLXG 4JB9G 2NXYA 4JZZA 3IDYA 2NXZA 4LSRG 4RFOG 4LSVG 4XNYG 1G9MG 4R4NA 3TIHA 2NY3A 3JWOA 4OLYG 3JWDA 4YDKG 5T33G 5F4PA 5F9WA 5I9QA 4RFNA 5F4LA 4JPWG 4I54A 4R4FA 1YYMG 4RZ8A 4DVWA 1GC1G 4OM0G 4DKUA 2NY6A 4JPVG 1G9NG 2B4CG 4H8WG 5F4UA 4LSTG 4YDLA 2I5YG 4OLZG 4XMPG 1RZJG 1YYLG 4OLUG 4S1RG 4JKPG 4J6RG 5FECC 2NY5G 3SE8G 4DVSA 4YE4G 4DVXA 4JDTG 3IDXG 4LSSG 4RWYA 4OLWG 3RJQA 3TGQA 4LSUG 5TE4G 4OM1G 4RX4E 4DKPA 4P9HG 3TGSA 5IGXG 3TGRA 1RZKG 2NY1A 4XNZA 2BF1A 4DVVA 4DKOA 4LAJA 2I60G 3HI1G 3NGBA 2NY0A 4DVRG 5F4RA 2QADA 2NY4A 5TE7G 3FUSA 4JM2E 5KJRG 4XVSG 4DKVA 4K0AA 4DKQA 4XVTG 4S1QG 4S1SG 4LSQG 5F9OG 4DVTA 4JZWA 3SE9G 5FA2A 4YDIG 4KA2A 5TE6G 4OLVG 3TGTA 3LQAG 2NY2A 4I53A 3U7YG 5CD5A 4R2GA 2NY7G 5CAYG 4YFLE 4DKRA 4LSPG 4YDJG 5F96G
chains in the Genus database with same CATH superfamily
4OLXG 4JB9G 2NXYA 4JZZA 3IDYA 2NXZA 4LSRG 4RFOG 4LSVG 4XNYG 1G9MG 4R4NA 3TIHA 2NY3A 3JWOA 4OLYG 3JWDA 4YDKG 5T33G 5F4PA 5F9WA 5I9QA 4RFNA 5F4LA 4JPWG 4I54A 4R4FA 1YYMG 4RZ8A 4DVWA 1GC1G 4OM0G 4DKUA 2NY6A 4JPVG 1G9NG 2B4CG 4H8WG 5F4UA 4LSTG 4YDLA 2I5YG 4OLZG 4XMPG 1RZJG 1YYLG 4OLUG 4S1RG 4JKPG 4J6RG 5FECC 2NY5G 3SE8G 4DVSA 4YE4G 4DVXA 4JDTG 3IDXG 4LSSG 4RWYA 4OLWG 3RJQA 3TGQA 4LSUG 5TE4G 4OM1G 4RX4E 4DKPA 4P9HG 3TGSA 5IGXG 3TGRA 1RZKG 2NY1A 4XNZA 2BF1A 4DVVA 4DKOA 4LAJA 2I60G 3HI1G 3NGBA 2NY0A 4DVRG 5F4RA 2QADA 2NY4A 5TE7G 3FUSA 4JM2E 5KJRG 4XVSG 4DKVA 4K0AA 4DKQA 4XVTG 4S1QG 4S1SG 4LSQG 5F9OG 4DVTA 4JZWA 3SE9G 5FA2A 4YDIG 4KA2A 5TE6G 4OLVG 3TGTA 3LQAG 2NY2A 4I53A 3U7YG 5CD5A 4R2GA 2NY7G 5CAYG 4YFLE 4DKRA 4LSPG 4YDJG 5F96G
chains in the Genus database with same CATH topology
4OLXG 4JB9G 2NXYA 4JZZA 3IDYA 2NXZA 4LSRG 4RFOG 4LSVG 4XNYG 1G9MG 4R4NA 3TIHA 2NY3A 3JWOA 4OLYG 3JWDA 4YDKG 5T33G 5F4PA 5F9WA 5I9QA 4RFNA 5F4LA 4JPWG 4I54A 4R4FA 1YYMG 4RZ8A 4DVWA 1GC1G 4OM0G 4DKUA 2NY6A 4JPVG 1G9NG 2B4CG 4H8WG 5F4UA 4LSTG 4YDLA 2I5YG 4OLZG 4XMPG 1RZJG 1YYLG 4OLUG 4S1RG 4JKPG 4J6RG 5FECC 2NY5G 3SE8G 4DVSA 4YE4G 4DVXA 4JDTG 3IDXG 4LSSG 4RWYA 4OLWG 3RJQA 3TGQA 4LSUG 5TE4G 4OM1G 4RX4E 4DKPA 4P9HG 3TGSA 5IGXG 3TGRA 1RZKG 2NY1A 4XNZA 2BF1A 4DVVA 4DKOA 4LAJA 2I60G 3HI1G 3NGBA 2NY0A 4DVRG 5F4RA 2QADA 2NY4A 5TE7G 3FUSA 4JM2E 5KJRG 4XVSG 4DKVA 4K0AA 4DKQA 4XVTG 4S1QG 4S1SG 4LSQG 5F9OG 4DVTA 4JZWA 3SE9G 5FA2A 4YDIG 4KA2A 5TE6G 4OLVG 3TGTA 3LQAG 2NY2A 4I53A 3U7YG 5CD5A 4R2GA 2NY7G 5CAYG 4YFLE 4DKRA 4LSPG 4YDJG 5F96G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OLX G;  4JB9 G;  2NXY A;  4JZZ A;  3IDY A;  2NXZ A;  4LSR G;  4RFO G;  4LSV G;  4XNY G;  1G9M G;  4R4N A;  3TIH A;  2NY3 A;  3JWO A;  4OLY G;  3JWD A;  4YDK G;  5T33 G;  5F4P A;  5F9W A;  5I9Q A;  4RFN A;  5F4L A;  4JPW G;  4I54 A;  4R4F A;  1YYM G;  4RZ8 A;  4DVW A;  1GC1 G;  4OM0 G;  4DKU A;  2NY6 A;  4JPV G;  1G9N G;  2B4C G;  4H8W G;  5F4U A;  4LST G;  4YDL A;  2I5Y G;  4OLZ G;  4XMP G;  1RZJ G;  1YYL G;  4OLU G;  4S1R G;  4JKP G;  4J6R G;  5FEC C;  2NY5 G;  3SE8 G;  4DVS A;  4YE4 G;  4DVX A;  4JDT G;  3IDX G;  4LSS G;  4RWY A;  4OLW G;  3RJQ A;  3TGQ A;  4LSU G;  5TE4 G;  4OM1 G;  4RX4 E;  4DKP A;  4P9H G;  3TGS A;  5IGX G;  3TGR A;  1RZK G;  2NY1 A;  4XNZ A;  2BF1 A;  4DVV A;  4DKO A;  4LAJ A;  2I60 G;  3HI1 G;  3NGB A;  2NY0 A;  4DVR G;  5F4R A;  2QAD A;  2NY4 A;  5TE7 G;  3FUS A;  4JM2 E;  5KJR G;  4XVS G;  4DKV A;  4K0A A;  4DKQ A;  4XVT G;  4S1Q G;  4S1S G;  4LSQ G;  5F9O G;  4DVT A;  4JZW A;  3SE9 G;  5FA2 A;  4YDI G;  4KA2 A;  5TE6 G;  4OLV G;  3TGT A;  3LQA G;  2NY2 A;  4I53 A;  3U7Y G;  5CD5 A;  4R2G A;  2NY7 G;  5CAY G;  4YFL E;  4DKR A;  4LSP G;  4YDJ G;  5F96 G; 
#chains in the Genus database with same CATH topology
 4OLX G;  4JB9 G;  2NXY A;  4JZZ A;  3IDY A;  2NXZ A;  4LSR G;  4RFO G;  4LSV G;  4XNY G;  1G9M G;  4R4N A;  3TIH A;  2NY3 A;  3JWO A;  4OLY G;  3JWD A;  4YDK G;  5T33 G;  5F4P A;  5F9W A;  5I9Q A;  4RFN A;  5F4L A;  4JPW G;  4I54 A;  4R4F A;  1YYM G;  4RZ8 A;  4DVW A;  1GC1 G;  4OM0 G;  4DKU A;  2NY6 A;  4JPV G;  1G9N G;  2B4C G;  4H8W G;  5F4U A;  4LST G;  4YDL A;  2I5Y G;  4OLZ G;  4XMP G;  1RZJ G;  1YYL G;  4OLU G;  4S1R G;  4JKP G;  4J6R G;  5FEC C;  2NY5 G;  3SE8 G;  4DVS A;  4YE4 G;  4DVX A;  4JDT G;  3IDX G;  4LSS G;  4RWY A;  4OLW G;  3RJQ A;  3TGQ A;  4LSU G;  5TE4 G;  4OM1 G;  4RX4 E;  4DKP A;  4P9H G;  3TGS A;  5IGX G;  3TGR A;  1RZK G;  2NY1 A;  4XNZ A;  2BF1 A;  4DVV A;  4DKO A;  4LAJ A;  2I60 G;  3HI1 G;  3NGB A;  2NY0 A;  4DVR G;  5F4R A;  2QAD A;  2NY4 A;  5TE7 G;  3FUS A;  4JM2 E;  5KJR G;  4XVS G;  4DKV A;  4K0A A;  4DKQ A;  4XVT G;  4S1Q G;  4S1S G;  4LSQ G;  5F9O G;  4DVT A;  4JZW A;  3SE9 G;  5FA2 A;  4YDI G;  4KA2 A;  5TE6 G;  4OLV G;  3TGT A;  3LQA G;  2NY2 A;  4I53 A;  3U7Y G;  5CD5 A;  4R2G A;  2NY7 G;  5CAY G;  4YFL E;  4DKR A;  4LSP G;  4YDJ G;  5F96 G; 
#chains in the Genus database with same CATH homology
 4OLX G;  4JB9 G;  2NXY A;  4JZZ A;  3IDY A;  2NXZ A;  4LSR G;  4RFO G;  4LSV G;  4XNY G;  1G9M G;  4R4N A;  3TIH A;  2NY3 A;  3JWO A;  4OLY G;  3JWD A;  4YDK G;  5T33 G;  5F4P A;  5F9W A;  5I9Q A;  4RFN A;  5F4L A;  4JPW G;  4I54 A;  4R4F A;  1YYM G;  4RZ8 A;  4DVW A;  1GC1 G;  4OM0 G;  4DKU A;  2NY6 A;  4JPV G;  1G9N G;  2B4C G;  4H8W G;  5F4U A;  4LST G;  4YDL A;  2I5Y G;  4OLZ G;  4XMP G;  1RZJ G;  1YYL G;  4OLU G;  4S1R G;  4JKP G;  4J6R G;  5FEC C;  2NY5 G;  3SE8 G;  4DVS A;  4YE4 G;  4DVX A;  4JDT G;  3IDX G;  4LSS G;  4RWY A;  4OLW G;  3RJQ A;  3TGQ A;  4LSU G;  5TE4 G;  4OM1 G;  4RX4 E;  4DKP A;  4P9H G;  3TGS A;  5IGX G;  3TGR A;  1RZK G;  2NY1 A;  4XNZ A;  2BF1 A;  4DVV A;  4DKO A;  4LAJ A;  2I60 G;  3HI1 G;  3NGB A;  2NY0 A;  4DVR G;  5F4R A;  2QAD A;  2NY4 A;  5TE7 G;  3FUS A;  4JM2 E;  5KJR G;  4XVS G;  4DKV A;  4K0A A;  4DKQ A;  4XVT G;  4S1Q G;  4S1S G;  4LSQ G;  5F9O G;  4DVT A;  4JZW A;  3SE9 G;  5FA2 A;  4YDI G;  4KA2 A;  5TE6 G;  4OLV G;  3TGT A;  3LQA G;  2NY2 A;  4I53 A;  3U7Y G;  5CD5 A;  4R2G A;  2NY7 G;  5CAY G;  4YFL E;  4DKR A;  4LSP G;  4YDJ G;  5F96 G; 
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similar chains in the pdb database (?% sequence similarity)

 
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