4JS2A

Crystal structure of human beta-galactoside alpha-2,6-sialyltransferase 1 in complex with cmp
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
318
structure length
318
Chain Sequence
PEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSEWEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKRFLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPGFRTIHC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of human alpha-2,6-sialyltransferase reveals the binding mode of complex glycans
doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Beta-galactoside alpha-2,6-sialyltransferase 1
total genus 110
structure length 318
sequence length 318
ec nomenclature ec 2.4.99.1: Beta-galactoside alpha-(2,6)-sialyltransferase.
pdb deposition date 2013-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00777 Glyco_transf_29 Glycosyltransferase family 29 (sialyltransferase)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1480.20 Alpha Beta Alpha-Beta Complex sialyltransferase cstii, chain A sialyltransferase cstii, chain A 4js2A00
2WMLA 2WNBA 4JS2A 5BO8A 4JS1A 5BO6A 5BO7A 2WNFA 5BO9A 5CXYA 4MPSA
chains in the Genus database with same CATH superfamily
2X61A 4JS2A 2WQQA 2X63A 2WNFA 5CXYA 5BO6A 2P56A 2P2VA 2WMLA 2WNBA 5BO8A 4JS1A 2X62A 5BO9A 1RO7A 1RO8A 5BO7A 4MPSA 2DRJA
chains in the Genus database with same CATH topology
2WMLA 2WNBA 4JS2A 5BO8A 4JS1A 5BO6A 5BO7A 2WNFA 5BO9A 5CXYA 4MPSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WML A;  2WNB A;  4JS2 A;  5BO8 A;  4JS1 A;  5BO6 A;  5BO7 A;  2WNF A;  5BO9 A;  5CXY A;  4MPS A; 
#chains in the Genus database with same CATH topology
 2X61 A;  4JS2 A;  2WQQ A;  2X63 A;  2WNF A;  5CXY A;  5BO6 A;  2P56 A;  2P2V A;  2WML A;  2WNB A;  5BO8 A;  4JS1 A;  2X62 A;  5BO9 A;  1RO7 A;  1RO8 A;  5BO7 A;  4MPS A;  2DRJ A; 
#chains in the Genus database with same CATH homology
 2WML A;  2WNB A;  4JS2 A;  5BO8 A;  4JS1 A;  5BO6 A;  5BO7 A;  2WNF A;  5BO9 A;  5CXY A;  4MPS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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