4LSTG

Crystal structure of broadly and potently neutralizing antibody vrc01 in complex with hiv-1 clade c strain zm176.66 gp120
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
355
structure length
339
Chain Sequence
VWKEAKTTLFCASDAKAYEREVHNVWATHACVPTDPNPQEMALGNVTENFNMWKNDMVDQMHEDIISLWDQSLKPCVKLTGGSTVTQACPKVSFDPIPIHYCAPAGYAILKCNNETFEGTGPCNNVSTVQCTHGIKPVVSTQLLLNGSLAKEEIVIRSENLTDNAKTIIVHLKESVEIVCTRPGDTRQAHCNISEEKWNKTLQKVSKILQEHFPNKAIKFEPHSGGDLEITTHSFNCRGEFFYCNTTKLFNGTYNSSNTTITLPCRIKQIVNMWQGVGRAMYAPPIKGNITCKSIITGLLLTRDGGNDDNDTETFRPGGGDMRDNWRSELYKYKVVEIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
pubmed doi rcsb
molecule tags Viral protein/immune system
source organism Human immunodeficiency virus 1
molecule keywords ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C
total genus 82
structure length 339
sequence length 355
ec nomenclature
pdb deposition date 2013-07-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00516 GP120 Envelope glycoprotein GP120
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 4lstG01
4K0AA 4OLUG 2NY6A 5FECC 5F9WA 5TE6G 2B4CG 4XVTG 4YDJG 4JZZA 5I9QA 4DKRA 5CAYG 3IDXG 4I54A 4OLYG 2QADA 4RFOG 5T33G 4OM0G 3JWDA 4S1RG 5TE7G 4JM2E 3TGTA 5F4RA 4YDLA 2NY3A 4LSRG 4OLVG 1GC1G 1RZKG 3RJQA 4LSUG 3TGRA 1YYLG 5TE4G 4LSSG 3HI1G 4DKUA 4RFNA 2NY1A 4JPWG 1G9NG 4DVXA 2I60G 4JB9G 1RZJG 4JPVG 4XVSG 4KA2A 4DKQA 4LSTG 2NY0A 3LQAG 3U7YG 4LSVG 4XMPG 3NGBA 4DKVA 5F4PA 4LAJA 2NY5G 4YE4G 4DKPA 4OLWG 5IGXG 3TGSA 4I53A 4JDTG 3SE8G 4XNYG 4RX4E 4LSQG 4DVTA 3IDYA 5F4UA 2I5YG 5CD5A 4YDIG 4R4FA 4DKOA 3JWOA 3FUSA 3SE9G 4DVWA 2NY7G 4S1SG 1G9MG 4RWYA 2NY2A 4S1QG 1YYMG 4J6RG 4LSPG 4OLZG 5F96G 5KJRG 4JZWA 2BF1A 4OLXG 5F9OG 4DVSA 4H8WG 4P9HG 3TIHA 4YFLE 4XNZA 3TGQA 4JKPG 4DVVA 2NY4A 4R2GA 5FA2A 4DVRG 4OM1G 4RZ8A 4YDKG 4R4NA 2NXZA 5F4LA 2NXYA
chains in the Genus database with same CATH superfamily
4K0AA 4OLUG 2NY6A 5FECC 5F9WA 5TE6G 2B4CG 4XVTG 4YDJG 4JZZA 5I9QA 4DKRA 5CAYG 3IDXG 4I54A 4OLYG 2QADA 4RFOG 5T33G 4OM0G 3JWDA 4S1RG 5TE7G 4JM2E 3TGTA 5F4RA 4YDLA 2NY3A 4LSRG 4OLVG 1GC1G 1RZKG 3RJQA 4LSUG 3TGRA 1YYLG 5TE4G 4LSSG 3HI1G 4DKUA 4RFNA 2NY1A 4JPWG 1G9NG 4DVXA 2I60G 4JB9G 1RZJG 4JPVG 4XVSG 4KA2A 4DKQA 4LSTG 2NY0A 3LQAG 3U7YG 4LSVG 4XMPG 3NGBA 4DKVA 5F4PA 4LAJA 2NY5G 4YE4G 4DKPA 4OLWG 5IGXG 3TGSA 4I53A 4JDTG 3SE8G 4XNYG 4RX4E 4LSQG 4DVTA 3IDYA 5F4UA 2I5YG 5CD5A 4YDIG 4R4FA 4DKOA 3JWOA 3FUSA 3SE9G 4DVWA 2NY7G 4S1SG 1G9MG 4RWYA 2NY2A 4S1QG 1YYMG 4J6RG 4LSPG 4OLZG 5F96G 5KJRG 4JZWA 2BF1A 4OLXG 5F9OG 4DVSA 4H8WG 4P9HG 3TIHA 4YFLE 4XNZA 3TGQA 4JKPG 4DVVA 2NY4A 4R2GA 5FA2A 4DVRG 4OM1G 4RZ8A 4YDKG 4R4NA 2NXZA 5F4LA 2NXYA
chains in the Genus database with same CATH topology
4K0AA 4OLUG 2NY6A 5FECC 5F9WA 5TE6G 2B4CG 4XVTG 4YDJG 4JZZA 5I9QA 4DKRA 5CAYG 3IDXG 4I54A 4OLYG 2QADA 4RFOG 5T33G 4OM0G 3JWDA 4S1RG 5TE7G 4JM2E 3TGTA 5F4RA 4YDLA 2NY3A 4LSRG 4OLVG 1GC1G 1RZKG 3RJQA 4LSUG 3TGRA 1YYLG 5TE4G 4LSSG 3HI1G 4DKUA 4RFNA 2NY1A 4JPWG 1G9NG 4DVXA 2I60G 4JB9G 1RZJG 4JPVG 4XVSG 4KA2A 4DKQA 4LSTG 2NY0A 3LQAG 3U7YG 4LSVG 4XMPG 3NGBA 4DKVA 5F4PA 4LAJA 2NY5G 4YE4G 4DKPA 4OLWG 5IGXG 3TGSA 4I53A 4JDTG 3SE8G 4XNYG 4RX4E 4LSQG 4DVTA 3IDYA 5F4UA 2I5YG 5CD5A 4YDIG 4R4FA 4DKOA 3JWOA 3FUSA 3SE9G 4DVWA 2NY7G 4S1SG 1G9MG 4RWYA 2NY2A 4S1QG 1YYMG 4J6RG 4LSPG 4OLZG 5F96G 5KJRG 4JZWA 2BF1A 4OLXG 5F9OG 4DVSA 4H8WG 4P9HG 3TIHA 4YFLE 4XNZA 3TGQA 4JKPG 4DVVA 2NY4A 4R2GA 5FA2A 4DVRG 4OM1G 4RZ8A 4YDKG 4R4NA 2NXZA 5F4LA 2NXYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4K0A A;  4OLU G;  2NY6 A;  5FEC C;  5F9W A;  5TE6 G;  2B4C G;  4XVT G;  4YDJ G;  4JZZ A;  5I9Q A;  4DKR A;  5CAY G;  3IDX G;  4I54 A;  4OLY G;  2QAD A;  4RFO G;  5T33 G;  4OM0 G;  3JWD A;  4S1R G;  5TE7 G;  4JM2 E;  3TGT A;  5F4R A;  4YDL A;  2NY3 A;  4LSR G;  4OLV G;  1GC1 G;  1RZK G;  3RJQ A;  4LSU G;  3TGR A;  1YYL G;  5TE4 G;  4LSS G;  3HI1 G;  4DKU A;  4RFN A;  2NY1 A;  4JPW G;  1G9N G;  4DVX A;  2I60 G;  4JB9 G;  1RZJ G;  4JPV G;  4XVS G;  4KA2 A;  4DKQ A;  4LST G;  2NY0 A;  3LQA G;  3U7Y G;  4LSV G;  4XMP G;  3NGB A;  4DKV A;  5F4P A;  4LAJ A;  2NY5 G;  4YE4 G;  4DKP A;  4OLW G;  5IGX G;  3TGS A;  4I53 A;  4JDT G;  3SE8 G;  4XNY G;  4RX4 E;  4LSQ G;  4DVT A;  3IDY A;  5F4U A;  2I5Y G;  5CD5 A;  4YDI G;  4R4F A;  4DKO A;  3JWO A;  3FUS A;  3SE9 G;  4DVW A;  2NY7 G;  4S1S G;  1G9M G;  4RWY A;  2NY2 A;  4S1Q G;  1YYM G;  4J6R G;  4LSP G;  4OLZ G;  5F96 G;  5KJR G;  4JZW A;  2BF1 A;  4OLX G;  5F9O G;  4DVS A;  4H8W G;  4P9H G;  3TIH A;  4YFL E;  4XNZ A;  3TGQ A;  4JKP G;  4DVV A;  2NY4 A;  4R2G A;  5FA2 A;  4DVR G;  4OM1 G;  4RZ8 A;  4YDK G;  4R4N A;  2NXZ A;  5F4L A;  2NXY A; 
#chains in the Genus database with same CATH topology
 4K0A A;  4OLU G;  2NY6 A;  5FEC C;  5F9W A;  5TE6 G;  2B4C G;  4XVT G;  4YDJ G;  4JZZ A;  5I9Q A;  4DKR A;  5CAY G;  3IDX G;  4I54 A;  4OLY G;  2QAD A;  4RFO G;  5T33 G;  4OM0 G;  3JWD A;  4S1R G;  5TE7 G;  4JM2 E;  3TGT A;  5F4R A;  4YDL A;  2NY3 A;  4LSR G;  4OLV G;  1GC1 G;  1RZK G;  3RJQ A;  4LSU G;  3TGR A;  1YYL G;  5TE4 G;  4LSS G;  3HI1 G;  4DKU A;  4RFN A;  2NY1 A;  4JPW G;  1G9N G;  4DVX A;  2I60 G;  4JB9 G;  1RZJ G;  4JPV G;  4XVS G;  4KA2 A;  4DKQ A;  4LST G;  2NY0 A;  3LQA G;  3U7Y G;  4LSV G;  4XMP G;  3NGB A;  4DKV A;  5F4P A;  4LAJ A;  2NY5 G;  4YE4 G;  4DKP A;  4OLW G;  5IGX G;  3TGS A;  4I53 A;  4JDT G;  3SE8 G;  4XNY G;  4RX4 E;  4LSQ G;  4DVT A;  3IDY A;  5F4U A;  2I5Y G;  5CD5 A;  4YDI G;  4R4F A;  4DKO A;  3JWO A;  3FUS A;  3SE9 G;  4DVW A;  2NY7 G;  4S1S G;  1G9M G;  4RWY A;  2NY2 A;  4S1Q G;  1YYM G;  4J6R G;  4LSP G;  4OLZ G;  5F96 G;  5KJR G;  4JZW A;  2BF1 A;  4OLX G;  5F9O G;  4DVS A;  4H8W G;  4P9H G;  3TIH A;  4YFL E;  4XNZ A;  3TGQ A;  4JKP G;  4DVV A;  2NY4 A;  4R2G A;  5FA2 A;  4DVR G;  4OM1 G;  4RZ8 A;  4YDK G;  4R4N A;  2NXZ A;  5F4L A;  2NXY A; 
#chains in the Genus database with same CATH homology
 4K0A A;  4OLU G;  2NY6 A;  5FEC C;  5F9W A;  5TE6 G;  2B4C G;  4XVT G;  4YDJ G;  4JZZ A;  5I9Q A;  4DKR A;  5CAY G;  3IDX G;  4I54 A;  4OLY G;  2QAD A;  4RFO G;  5T33 G;  4OM0 G;  3JWD A;  4S1R G;  5TE7 G;  4JM2 E;  3TGT A;  5F4R A;  4YDL A;  2NY3 A;  4LSR G;  4OLV G;  1GC1 G;  1RZK G;  3RJQ A;  4LSU G;  3TGR A;  1YYL G;  5TE4 G;  4LSS G;  3HI1 G;  4DKU A;  4RFN A;  2NY1 A;  4JPW G;  1G9N G;  4DVX A;  2I60 G;  4JB9 G;  1RZJ G;  4JPV G;  4XVS G;  4KA2 A;  4DKQ A;  4LST G;  2NY0 A;  3LQA G;  3U7Y G;  4LSV G;  4XMP G;  3NGB A;  4DKV A;  5F4P A;  4LAJ A;  2NY5 G;  4YE4 G;  4DKP A;  4OLW G;  5IGX G;  3TGS A;  4I53 A;  4JDT G;  3SE8 G;  4XNY G;  4RX4 E;  4LSQ G;  4DVT A;  3IDY A;  5F4U A;  2I5Y G;  5CD5 A;  4YDI G;  4R4F A;  4DKO A;  3JWO A;  3FUS A;  3SE9 G;  4DVW A;  2NY7 G;  4S1S G;  1G9M G;  4RWY A;  2NY2 A;  4S1Q G;  1YYM G;  4J6R G;  4LSP G;  4OLZ G;  5F96 G;  5KJR G;  4JZW A;  2BF1 A;  4OLX G;  5F9O G;  4DVS A;  4H8W G;  4P9H G;  3TIH A;  4YFL E;  4XNZ A;  3TGQ A;  4JKP G;  4DVV A;  2NY4 A;  4R2G A;  5FA2 A;  4DVR G;  4OM1 G;  4RZ8 A;  4YDK G;  4R4N A;  2NXZ A;  5F4L A;  2NXY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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