4MPSA

Crystal structure of rat beta-galactoside alpha-2,6-sialyltransferase 1 (st6gal1), northeast structural genomics consortium target rnr367a
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
300
structure length
293
Chain Sequence
PRLLKIWRNYLNMNKYKVSYKGPGPGVKFSVEALRCHLRDHVNVSMIEATDFPFNTTEWEGYLPKENFRTKVGPWQRCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGSKTTIRLMNSQLVTTEKRFLKDSLYTEGILIVWDPSVYHADIPKWYQKPDYNFFETYKSYRRLNPSQPFYILKPQMPWELWDIIQEISADLIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYHQTMGAYHPLLFEKNMVKHLNEGTDEDIYLFGKATLSGFRNIRC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Enzymatic Basis for N-Glycan Sialylation: STRUCTURE OF RAT alpha 2,6-SIALYLTRANSFERASE (ST6GAL1) REVEALS CONSERVED AND UNIQUE FEATURES FOR GLYCAN SIALYLATION.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Beta-galactoside alpha-2,6-sialyltransferase 1
total genus 87
structure length 293
sequence length 300
chains with identical sequence B
ec nomenclature ec 2.4.99.1: Beta-galactoside alpha-(2,6)-sialyltransferase.
pdb deposition date 2013-09-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00777 Glyco_transf_29 Glycosyltransferase family 29 (sialyltransferase)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1480.20 Alpha Beta Alpha-Beta Complex sialyltransferase cstii, chain A sialyltransferase cstii, chain A 4mpsA00
2WNBA 4MPSA 4JS1A 5BO6A 5BO9A 2WNFA 4JS2A 2WMLA 5BO8A 5CXYA 5BO7A
chains in the Genus database with same CATH superfamily
2X61A 2X62A 4JS1A 4JS2A 2P2VA 2WMLA 1RO8A 2DRJA 2X63A 2P56A 5BO6A 2WQQA 5BO9A 5CXYA 1RO7A 2WNBA 4MPSA 2WNFA 5BO8A 5BO7A
chains in the Genus database with same CATH topology
2WNBA 4MPSA 4JS1A 5BO6A 5BO9A 2WNFA 4JS2A 2WMLA 5BO8A 5CXYA 5BO7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WNB A;  4MPS A;  4JS1 A;  5BO6 A;  5BO9 A;  2WNF A;  4JS2 A;  2WML A;  5BO8 A;  5CXY A;  5BO7 A; 
#chains in the Genus database with same CATH topology
 2X61 A;  2X62 A;  4JS1 A;  4JS2 A;  2P2V A;  2WML A;  1RO8 A;  2DRJ A;  2X63 A;  2P56 A;  5BO6 A;  2WQQ A;  5BO9 A;  5CXY A;  1RO7 A;  2WNB A;  4MPS A;  2WNF A;  5BO8 A;  5BO7 A; 
#chains in the Genus database with same CATH homology
 2WNB A;  4MPS A;  4JS1 A;  5BO6 A;  5BO9 A;  2WNF A;  4JS2 A;  2WML A;  5BO8 A;  5CXY A;  5BO7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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