4NWQA

Computationally designed two-component self-assembling tetrahedral cage, t33-21, crystallized in space group f4132
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
148
structure length
148
Chain Sequence
KDSPIIEANGTLDELTSFIGEAKHYVDEEMKGILEEIQNDIYKIMGEIGSKGKIEGISEERIAWLLKLILRYMEMVNLKSFVLPGGTLESAKLDVCRTIARRALRKVLTVTREFGIGAEAAAYLLALSDLLFLLARVIEIEKNKLKEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Accurate design of co-assembling multi-component protein nanomaterials.
pubmed doi rcsb
molecule tags Protein binding
source organism Pyrococcus horikoshii
molecule keywords Putative uncharacterized protein PH0671
total genus 62
structure length 148
sequence length 148
ec nomenclature
pdb deposition date 2013-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01923 Cob_adeno_trans Cobalamin adenosyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1200.10 Mainly Alpha Up-down Bundle Hypothetical Protein Ta1238; Chain: A; Cobalamin adenosyltransferase-like 4nwqA00
4NWPA 2ZHZA 1RTYA 5CY5A 2R6XA 2ZHYA 3CI4A 3CI1A 1WY1A 1WOZA 1NOGA 3CI3A 2R6TA 2NT8A 3KE5A 2G2DA 2IDXA 3GAHA 3GAJA 3GAIA 1NIGA 2AH6A 3KE4A 4NWQA 1WVTA 5CY5B
chains in the Genus database with same CATH superfamily
4NWPA 2ZHZA 1RTYA 5CY5A 2R6XA 2ZHYA 3CI4A 3CI1A 1WY1A 1WOZA 1NOGA 3CI3A 2R6TA 2NT8A 3KE5A 2G2DA 2IDXA 3GAHA 3GAJA 3GAIA 1NIGA 2AH6A 3KE4A 4NWQA 1WVTA 5CY5B
chains in the Genus database with same CATH topology
4NWPA 2ZHZA 1RTYA 5CY5A 2R6XA 2ZHYA 3CI4A 3CI1A 1WY1A 1WOZA 1NOGA 3CI3A 2R6TA 2NT8A 3KE5A 2G2DA 2IDXA 3GAHA 3GAJA 3GAIA 1NIGA 2AH6A 3KE4A 4NWQA 1WVTA 5CY5B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NWP A;  2ZHZ A;  1RTY A;  5CY5 A;  2R6X A;  2ZHY A;  3CI4 A;  3CI1 A;  1WY1 A;  1WOZ A;  1NOG A;  3CI3 A;  2R6T A;  2NT8 A;  3KE5 A;  2G2D A;  2IDX A;  3GAH A;  3GAJ A;  3GAI A;  1NIG A;  2AH6 A;  3KE4 A;  4NWQ A;  1WVT A;  5CY5 B; 
#chains in the Genus database with same CATH topology
 4NWP A;  2ZHZ A;  1RTY A;  5CY5 A;  2R6X A;  2ZHY A;  3CI4 A;  3CI1 A;  1WY1 A;  1WOZ A;  1NOG A;  3CI3 A;  2R6T A;  2NT8 A;  3KE5 A;  2G2D A;  2IDX A;  3GAH A;  3GAJ A;  3GAI A;  1NIG A;  2AH6 A;  3KE4 A;  4NWQ A;  1WVT A;  5CY5 B; 
#chains in the Genus database with same CATH homology
 4NWP A;  2ZHZ A;  1RTY A;  5CY5 A;  2R6X A;  2ZHY A;  3CI4 A;  3CI1 A;  1WY1 A;  1WOZ A;  1NOG A;  3CI3 A;  2R6T A;  2NT8 A;  3KE5 A;  2G2D A;  2IDX A;  3GAH A;  3GAJ A;  3GAI A;  1NIG A;  2AH6 A;  3KE4 A;  4NWQ A;  1WVT A;  5CY5 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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