4OLWG

Crystal structure of antibody vrc07-g54h in complex with clade a/e 93th057 hiv-1 gp120 core
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
353
structure length
342
Chain Sequence
VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENFNMWKNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNDIRKAYCEINGTKWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHHFNCRGEFFYCNTTQLFNNTCIGKGCNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo.
pubmed doi rcsb
molecule tags Viral protein/immune system
source organism Human immunodeficiency virus 1
molecule keywords Envelope glycoprotein gp160
total genus 92
structure length 342
sequence length 353
ec nomenclature
pdb deposition date 2014-01-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 4olwG01
4DKRA 4LSQG 4OLZG 3JWOA 5F4LA 4RX4E 2B4CG 5KJRG 2NY3A 4YDLA 4DVRG 4LSSG 4S1RG 4R4NA 4OM0G 4OLXG 2NXZA 4S1QG 4OM1G 1RZJG 2NY7G 4YDJG 4JB9G 4XVSG 4YE4G 4YDIG 2NY6A 4J6RG 4K0AA 3TGRA 4OLUG 4OLWG 2NXYA 4JM2E 5I9QA 4XMPG 4R4FA 4DKOA 4DVVA 5CAYG 5IGXG 4LSPG 4I53A 3SE8G 5FECC 4XVTG 3SE9G 3TGQA 4JZWA 4JKPG 3IDYA 4LSUG 4XNYG 4H8WG 3U7YG 4OLVG 1G9NG 4YFLE 4XNZA 3IDXG 5F96G 3TGTA 1GC1G 4RFNA 4JDTG 2NY5G 4DKUA 3TIHA 4RWYA 5FA2A 4JPWG 5TE6G 5F4RA 1G9MG 5F4UA 4DKPA 3RJQA 2BF1A 4DVSA 4LSRG 4S1SG 4RZ8A 4DKQA 2NY2A 4LSVG 5T33G 4DKVA 1YYMG 1YYLG 4I54A 4R2GA 2I5YG 5CD5A 4P9HG 3TGSA 2NY1A 5TE7G 3JWDA 1RZKG 2NY0A 4DVTA 2I60G 4RFOG 4LAJA 5TE4G 4LSTG 4KA2A 4DVWA 4DVXA 5F9WA 4YDKG 3HI1G 3NGBA 4OLYG 2QADA 4JPVG 2NY4A 3FUSA 4JZZA 5F4PA 5F9OG 3LQAG
chains in the Genus database with same CATH superfamily
4DKRA 4LSQG 4OLZG 3JWOA 5F4LA 4RX4E 2B4CG 5KJRG 2NY3A 4YDLA 4DVRG 4LSSG 4S1RG 4R4NA 4OM0G 4OLXG 2NXZA 4S1QG 4OM1G 1RZJG 2NY7G 4YDJG 4JB9G 4XVSG 4YE4G 4YDIG 2NY6A 4J6RG 4K0AA 3TGRA 4OLUG 4OLWG 2NXYA 4JM2E 5I9QA 4XMPG 4R4FA 4DKOA 4DVVA 5CAYG 5IGXG 4LSPG 4I53A 3SE8G 5FECC 4XVTG 3SE9G 3TGQA 4JZWA 4JKPG 3IDYA 4LSUG 4XNYG 4H8WG 3U7YG 4OLVG 1G9NG 4YFLE 4XNZA 3IDXG 5F96G 3TGTA 1GC1G 4RFNA 4JDTG 2NY5G 4DKUA 3TIHA 4RWYA 5FA2A 4JPWG 5TE6G 5F4RA 1G9MG 5F4UA 4DKPA 3RJQA 2BF1A 4DVSA 4LSRG 4S1SG 4RZ8A 4DKQA 2NY2A 4LSVG 5T33G 4DKVA 1YYMG 1YYLG 4I54A 4R2GA 2I5YG 5CD5A 4P9HG 3TGSA 2NY1A 5TE7G 3JWDA 1RZKG 2NY0A 4DVTA 2I60G 4RFOG 4LAJA 5TE4G 4LSTG 4KA2A 4DVWA 4DVXA 5F9WA 4YDKG 3HI1G 3NGBA 4OLYG 2QADA 4JPVG 2NY4A 3FUSA 4JZZA 5F4PA 5F9OG 3LQAG
chains in the Genus database with same CATH topology
4DKRA 4LSQG 4OLZG 3JWOA 5F4LA 4RX4E 2B4CG 5KJRG 2NY3A 4YDLA 4DVRG 4LSSG 4S1RG 4R4NA 4OM0G 4OLXG 2NXZA 4S1QG 4OM1G 1RZJG 2NY7G 4YDJG 4JB9G 4XVSG 4YE4G 4YDIG 2NY6A 4J6RG 4K0AA 3TGRA 4OLUG 4OLWG 2NXYA 4JM2E 5I9QA 4XMPG 4R4FA 4DKOA 4DVVA 5CAYG 5IGXG 4LSPG 4I53A 3SE8G 5FECC 4XVTG 3SE9G 3TGQA 4JZWA 4JKPG 3IDYA 4LSUG 4XNYG 4H8WG 3U7YG 4OLVG 1G9NG 4YFLE 4XNZA 3IDXG 5F96G 3TGTA 1GC1G 4RFNA 4JDTG 2NY5G 4DKUA 3TIHA 4RWYA 5FA2A 4JPWG 5TE6G 5F4RA 1G9MG 5F4UA 4DKPA 3RJQA 2BF1A 4DVSA 4LSRG 4S1SG 4RZ8A 4DKQA 2NY2A 4LSVG 5T33G 4DKVA 1YYMG 1YYLG 4I54A 4R2GA 2I5YG 5CD5A 4P9HG 3TGSA 2NY1A 5TE7G 3JWDA 1RZKG 2NY0A 4DVTA 2I60G 4RFOG 4LAJA 5TE4G 4LSTG 4KA2A 4DVWA 4DVXA 5F9WA 4YDKG 3HI1G 3NGBA 4OLYG 2QADA 4JPVG 2NY4A 3FUSA 4JZZA 5F4PA 5F9OG 3LQAG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DKR A;  4LSQ G;  4OLZ G;  3JWO A;  5F4L A;  4RX4 E;  2B4C G;  5KJR G;  2NY3 A;  4YDL A;  4DVR G;  4LSS G;  4S1R G;  4R4N A;  4OM0 G;  4OLX G;  2NXZ A;  4S1Q G;  4OM1 G;  1RZJ G;  2NY7 G;  4YDJ G;  4JB9 G;  4XVS G;  4YE4 G;  4YDI G;  2NY6 A;  4J6R G;  4K0A A;  3TGR A;  4OLU G;  4OLW G;  2NXY A;  4JM2 E;  5I9Q A;  4XMP G;  4R4F A;  4DKO A;  4DVV A;  5CAY G;  5IGX G;  4LSP G;  4I53 A;  3SE8 G;  5FEC C;  4XVT G;  3SE9 G;  3TGQ A;  4JZW A;  4JKP G;  3IDY A;  4LSU G;  4XNY G;  4H8W G;  3U7Y G;  4OLV G;  1G9N G;  4YFL E;  4XNZ A;  3IDX G;  5F96 G;  3TGT A;  1GC1 G;  4RFN A;  4JDT G;  2NY5 G;  4DKU A;  3TIH A;  4RWY A;  5FA2 A;  4JPW G;  5TE6 G;  5F4R A;  1G9M G;  5F4U A;  4DKP A;  3RJQ A;  2BF1 A;  4DVS A;  4LSR G;  4S1S G;  4RZ8 A;  4DKQ A;  2NY2 A;  4LSV G;  5T33 G;  4DKV A;  1YYM G;  1YYL G;  4I54 A;  4R2G A;  2I5Y G;  5CD5 A;  4P9H G;  3TGS A;  2NY1 A;  5TE7 G;  3JWD A;  1RZK G;  2NY0 A;  4DVT A;  2I60 G;  4RFO G;  4LAJ A;  5TE4 G;  4LST G;  4KA2 A;  4DVW A;  4DVX A;  5F9W A;  4YDK G;  3HI1 G;  3NGB A;  4OLY G;  2QAD A;  4JPV G;  2NY4 A;  3FUS A;  4JZZ A;  5F4P A;  5F9O G;  3LQA G; 
#chains in the Genus database with same CATH topology
 4DKR A;  4LSQ G;  4OLZ G;  3JWO A;  5F4L A;  4RX4 E;  2B4C G;  5KJR G;  2NY3 A;  4YDL A;  4DVR G;  4LSS G;  4S1R G;  4R4N A;  4OM0 G;  4OLX G;  2NXZ A;  4S1Q G;  4OM1 G;  1RZJ G;  2NY7 G;  4YDJ G;  4JB9 G;  4XVS G;  4YE4 G;  4YDI G;  2NY6 A;  4J6R G;  4K0A A;  3TGR A;  4OLU G;  4OLW G;  2NXY A;  4JM2 E;  5I9Q A;  4XMP G;  4R4F A;  4DKO A;  4DVV A;  5CAY G;  5IGX G;  4LSP G;  4I53 A;  3SE8 G;  5FEC C;  4XVT G;  3SE9 G;  3TGQ A;  4JZW A;  4JKP G;  3IDY A;  4LSU G;  4XNY G;  4H8W G;  3U7Y G;  4OLV G;  1G9N G;  4YFL E;  4XNZ A;  3IDX G;  5F96 G;  3TGT A;  1GC1 G;  4RFN A;  4JDT G;  2NY5 G;  4DKU A;  3TIH A;  4RWY A;  5FA2 A;  4JPW G;  5TE6 G;  5F4R A;  1G9M G;  5F4U A;  4DKP A;  3RJQ A;  2BF1 A;  4DVS A;  4LSR G;  4S1S G;  4RZ8 A;  4DKQ A;  2NY2 A;  4LSV G;  5T33 G;  4DKV A;  1YYM G;  1YYL G;  4I54 A;  4R2G A;  2I5Y G;  5CD5 A;  4P9H G;  3TGS A;  2NY1 A;  5TE7 G;  3JWD A;  1RZK G;  2NY0 A;  4DVT A;  2I60 G;  4RFO G;  4LAJ A;  5TE4 G;  4LST G;  4KA2 A;  4DVW A;  4DVX A;  5F9W A;  4YDK G;  3HI1 G;  3NGB A;  4OLY G;  2QAD A;  4JPV G;  2NY4 A;  3FUS A;  4JZZ A;  5F4P A;  5F9O G;  3LQA G; 
#chains in the Genus database with same CATH homology
 4DKR A;  4LSQ G;  4OLZ G;  3JWO A;  5F4L A;  4RX4 E;  2B4C G;  5KJR G;  2NY3 A;  4YDL A;  4DVR G;  4LSS G;  4S1R G;  4R4N A;  4OM0 G;  4OLX G;  2NXZ A;  4S1Q G;  4OM1 G;  1RZJ G;  2NY7 G;  4YDJ G;  4JB9 G;  4XVS G;  4YE4 G;  4YDI G;  2NY6 A;  4J6R G;  4K0A A;  3TGR A;  4OLU G;  4OLW G;  2NXY A;  4JM2 E;  5I9Q A;  4XMP G;  4R4F A;  4DKO A;  4DVV A;  5CAY G;  5IGX G;  4LSP G;  4I53 A;  3SE8 G;  5FEC C;  4XVT G;  3SE9 G;  3TGQ A;  4JZW A;  4JKP G;  3IDY A;  4LSU G;  4XNY G;  4H8W G;  3U7Y G;  4OLV G;  1G9N G;  4YFL E;  4XNZ A;  3IDX G;  5F96 G;  3TGT A;  1GC1 G;  4RFN A;  4JDT G;  2NY5 G;  4DKU A;  3TIH A;  4RWY A;  5FA2 A;  4JPW G;  5TE6 G;  5F4R A;  1G9M G;  5F4U A;  4DKP A;  3RJQ A;  2BF1 A;  4DVS A;  4LSR G;  4S1S G;  4RZ8 A;  4DKQ A;  2NY2 A;  4LSV G;  5T33 G;  4DKV A;  1YYM G;  1YYL G;  4I54 A;  4R2G A;  2I5Y G;  5CD5 A;  4P9H G;  3TGS A;  2NY1 A;  5TE7 G;  3JWD A;  1RZK G;  2NY0 A;  4DVT A;  2I60 G;  4RFO G;  4LAJ A;  5TE4 G;  4LST G;  4KA2 A;  4DVW A;  4DVX A;  5F9W A;  4YDK G;  3HI1 G;  3NGB A;  4OLY G;  2QAD A;  4JPV G;  2NY4 A;  3FUS A;  4JZZ A;  5F4P A;  5F9O G;  3LQA G; 
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