4POPA

Thit with lmg139 bound
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
177
structure length
177
Chain Sequence
FNVRLLTEIAFMAALAFIISLIPNTVYGWIIVEIACIPILLLSLRRGLTAGLVGGLIWGILSMITGHAYILSLSQAFLEYLVAPVSLGIAGLFRQKTAPLKLAPVLLGTFVAVLLKYFFHFIAGIIFWSQYAWKGWGAVAYSLAVNGISGILTAIAAFVILIIFVKKFPKLFIHSNY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Design of Potent Small-Molecule Binders to the S-Component of the ECF Transporter for Thiamine.
pubmed doi rcsb
molecule tags Protein binding
source organism Lactococcus lactis subsp. cremoris
molecule keywords Thiamine transporter ThiT
total genus 70
structure length 177
sequence length 177
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09515 Thia_YuaJ Thiamine transporter protein (Thia_YuaJ)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1760.20 Mainly Alpha Orthogonal Bundle Arp2/3 complex 21 kDa subunit ARPC3 Arp2/3 complex 21 kDa subunit ARPC3 4popA00
4HZUS 4POVA 4Z7FA 4M58A 5D0YA 3P5NA 3RLBA 4N4DA 5KC4A 4MUUA 4POPA 4M5CA 4M5BA 5KC0A 5JSZC 4MESA 4TKRA 4MHWA 4RFSS 4DVEA 5D3MC 5KBWA 4HUQS
chains in the Genus database with same CATH superfamily
4HZUS 4POVA 3ULEE 4Z7FA 2P9IE 3RSEE 4M58A 5D0YA 2P9NE 3P5NA 4XEIE 3UKUE 2P9PE 3RLBA 4N4DA 3DXKE 5KC4A 3UKRE 1TYQE 2P9SE 2P9LE 4JD2E 4MUUA 4POPA 4M5BA 4M5CA 5KC0A 2P9KE 1U2VE 2P9UE 5JSZC 3DXME 4MESA 4TKRA 4MHWA 4RFSS 4DVEA 5D3MC 1K8KE 5KBWA 4HUQS
chains in the Genus database with same CATH topology
4HZUS 4POVA 4Z7FA 4M58A 5D0YA 3P5NA 3RLBA 4N4DA 5KC4A 4MUUA 4POPA 4M5CA 4M5BA 5KC0A 5JSZC 4MESA 4TKRA 4MHWA 4RFSS 4DVEA 5D3MC 5KBWA 4HUQS
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HZU S;  4POV A;  4Z7F A;  4M58 A;  5D0Y A;  3P5N A;  3RLB A;  4N4D A;  5KC4 A;  4MUU A;  4POP A;  4M5C A;  4M5B A;  5KC0 A;  5JSZ C;  4MES A;  4TKR A;  4MHW A;  4RFS S;  4DVE A;  5D3M C;  5KBW A;  4HUQ S; 
#chains in the Genus database with same CATH topology
 4HZU S;  4POV A;  3ULE E;  4Z7F A;  2P9I E;  3RSE E;  4M58 A;  5D0Y A;  2P9N E;  3P5N A;  4XEI E;  3UKU E;  2P9P E;  3RLB A;  4N4D A;  3DXK E;  5KC4 A;  3UKR E;  1TYQ E;  2P9S E;  2P9L E;  4JD2 E;  4MUU A;  4POP A;  4M5B A;  4M5C A;  5KC0 A;  2P9K E;  1U2V E;  2P9U E;  5JSZ C;  3DXM E;  4MES A;  4TKR A;  4MHW A;  4RFS S;  4DVE A;  5D3M C;  1K8K E;  5KBW A;  4HUQ S; 
#chains in the Genus database with same CATH homology
 4HZU S;  4POV A;  4Z7F A;  4M58 A;  5D0Y A;  3P5N A;  3RLB A;  4N4D A;  5KC4 A;  4MUU A;  4POP A;  4M5C A;  4M5B A;  5KC0 A;  5JSZ C;  4MES A;  4TKR A;  4MHW A;  4RFS S;  4DVE A;  5D3M C;  5KBW A;  4HUQ S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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