4POVA

Thit with lmg135 bound
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
178
structure length
178
Chain Sequence
KFNVRLLTEIAFMAALAFIISLIPNTVYGWIIVEIACIPILLLSLRRGLTAGLVGGLIWGILSMITGHAYILSLSQAFLEYLVAPVSLGIAGLFRQKTAPLKLAPVLLGTFVAVLLKYFFHFIAGIIFWSQYAWKGWGAVAYSLAVNGISGILTAIAAFVILIIFVKKFPKLFIHSNY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Design of Potent Small-Molecule Binders to the S-Component of the ECF Transporter for Thiamine.
pubmed doi rcsb
molecule keywords Thiamine transporter ThiT
molecule tags Protein binding
source organism Lactococcus lactis subsp. cremoris
total genus 70
structure length 178
sequence length 178
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09515 Thia_YuaJ Thiamine transporter protein (Thia_YuaJ)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1760.20 Mainly Alpha Orthogonal Bundle Arp2/3 complex 21 kDa subunit ARPC3 Arp2/3 complex 21 kDa subunit ARPC3 4povA00
4POVA 4MESA 4DVEA 4M5BA 5D3MC 5KC4A 4MHWA 4MUUA 4N4DA 4HZUS 5D0YA 4HUQS 4Z7FA 5KBWA 4TKRA 3P5NA 5JSZC 4M5CA 5KC0A 3RLBA 4RFSS 4POPA 4M58A
chains in the Genus database with same CATH superfamily
2P9UE 4POVA 4MESA 4DVEA 3DXKE 4M5BA 2P9IE 5D3MC 2P9KE 3ULEE 5KC4A 4MHWA 4MUUA 4N4DA 4XEIE 4HZUS 1K8KE 5D0YA 4HUQS 4Z7FA 3RSEE 5KBWA 4TKRA 2P9NE 3P5NA 3UKRE 2P9SE 5JSZC 3UKUE 4M5CA 5KC0A 3RLBA 4JD2E 1TYQE 4RFSS 2P9PE 3DXME 2P9LE 4POPA 1U2VE 4M58A
chains in the Genus database with same CATH topology
4POVA 4MESA 4DVEA 4M5BA 5D3MC 5KC4A 4MHWA 4MUUA 4N4DA 4HZUS 5D0YA 4HUQS 4Z7FA 5KBWA 4TKRA 3P5NA 5JSZC 4M5CA 5KC0A 3RLBA 4RFSS 4POPA 4M58A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4POV A;  4MES A;  4DVE A;  4M5B A;  5D3M C;  5KC4 A;  4MHW A;  4MUU A;  4N4D A;  4HZU S;  5D0Y A;  4HUQ S;  4Z7F A;  5KBW A;  4TKR A;  3P5N A;  5JSZ C;  4M5C A;  5KC0 A;  3RLB A;  4RFS S;  4POP A;  4M58 A; 
#chains in the Genus database with same CATH topology
 2P9U E;  4POV A;  4MES A;  4DVE A;  3DXK E;  4M5B A;  2P9I E;  5D3M C;  2P9K E;  3ULE E;  5KC4 A;  4MHW A;  4MUU A;  4N4D A;  4XEI E;  4HZU S;  1K8K E;  5D0Y A;  4HUQ S;  4Z7F A;  3RSE E;  5KBW A;  4TKR A;  2P9N E;  3P5N A;  3UKR E;  2P9S E;  5JSZ C;  3UKU E;  4M5C A;  5KC0 A;  3RLB A;  4JD2 E;  1TYQ E;  4RFS S;  2P9P E;  3DXM E;  2P9L E;  4POP A;  1U2V E;  4M58 A; 
#chains in the Genus database with same CATH homology
 4POV A;  4MES A;  4DVE A;  4M5B A;  5D3M C;  5KC4 A;  4MHW A;  4MUU A;  4N4D A;  4HZU S;  5D0Y A;  4HUQ S;  4Z7F A;  5KBW A;  4TKR A;  3P5N A;  5JSZ C;  4M5C A;  5KC0 A;  3RLB A;  4RFS S;  4POP A;  4M58 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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