4PT4A

Crystal structure analysis of n terminal region containing the dimerization domain and dna binding domain of hu protein(histone like protein-dna binding) from mycobacterium tuberculosis [h37rv]
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
99
structure length
99
Chain Sequence
MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFRPGAQFKAVVSGAQRLPAEG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors
pubmed doi rcsb
molecule keywords DNA-binding protein HU homolog
molecule tags Dna binding protein
source organism Mycobacterium tuberculosis
total genus 25
structure length 99
sequence length 99
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00216 Bac_DNA_binding Bacterial DNA-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.520.10 Few Secondary Structures Irregular HU Protein; Chain A IHF-like DNA-binding proteins 4pt4A00
4FMRA 4YEWC 2HT0B 4YFTA 1EXEA 3RHIA 4PT4A 2HT0A 2NDPA 4YEYA 1P78A 1P71A 5FBMA 2O97B 4P3VA 4DKYA 4YF0A 4QJNA 2O97A 4QJUA 1B8ZA 4N1VA 2IIEA 1P51A 4YEXA 1OWFB 2IIFA 1HUEA 4YFTC 4YEWA 1WTUA 1MULA 1OUZB 5L8ZA 1OWFA 1IHFB 4YFHA 1OUZA 1HUUA 1IHFA 5EKAA 1OWGB 1RIYA 2NP2A 1OWGA
chains in the Genus database with same CATH superfamily
4FMRA 4YEWC 2HT0B 4YFTA 1EXEA 3RHIA 4PT4A 2HT0A 2NDPA 4YEYA 1P78A 1P71A 5FBMA 2O97B 4P3VA 4DKYA 4YF0A 4QJNA 2O97A 4QJUA 1B8ZA 4N1VA 2IIEA 1P51A 4YEXA 1OWFB 2IIFA 1HUEA 4YFTC 4YEWA 1WTUA 1MULA 1OUZB 5L8ZA 1OWFA 1IHFB 4YFHA 1OUZA 1HUUA 1IHFA 5EKAA 1OWGB 1RIYA 2NP2A 1OWGA
chains in the Genus database with same CATH topology
4FMRA 4YEWC 2HT0B 4YFTA 1EXEA 3RHIA 4PT4A 2HT0A 2NDPA 4YEYA 1P78A 1P71A 5FBMA 2O97B 4P3VA 4DKYA 4YF0A 4QJNA 2O97A 4QJUA 1B8ZA 4N1VA 2IIEA 1P51A 4YEXA 1OWFB 2IIFA 1HUEA 4YFTC 4YEWA 1WTUA 1MULA 1OUZB 5L8ZA 1OWFA 1IHFB 4YFHA 1OUZA 1HUUA 1IHFA 5EKAA 1OWGB 1RIYA 2NP2A 1OWGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FMR A;  4YEW C;  2HT0 B;  4YFT A;  1EXE A;  3RHI A;  4PT4 A;  2HT0 A;  2NDP A;  4YEY A;  1P78 A;  1P71 A;  5FBM A;  2O97 B;  4P3V A;  4DKY A;  4YF0 A;  4QJN A;  2O97 A;  4QJU A;  1B8Z A;  4N1V A;  2IIE A;  1P51 A;  4YEX A;  1OWF B;  2IIF A;  1HUE A;  4YFT C;  4YEW A;  1WTU A;  1MUL A;  1OUZ B;  5L8Z A;  1OWF A;  1IHF B;  4YFH A;  1OUZ A;  1HUU A;  1IHF A;  5EKA A;  1OWG B;  1RIY A;  2NP2 A;  1OWG A; 
#chains in the Genus database with same CATH topology
 4FMR A;  4YEW C;  2HT0 B;  4YFT A;  1EXE A;  3RHI A;  4PT4 A;  2HT0 A;  2NDP A;  4YEY A;  1P78 A;  1P71 A;  5FBM A;  2O97 B;  4P3V A;  4DKY A;  4YF0 A;  4QJN A;  2O97 A;  4QJU A;  1B8Z A;  4N1V A;  2IIE A;  1P51 A;  4YEX A;  1OWF B;  2IIF A;  1HUE A;  4YFT C;  4YEW A;  1WTU A;  1MUL A;  1OUZ B;  5L8Z A;  1OWF A;  1IHF B;  4YFH A;  1OUZ A;  1HUU A;  1IHF A;  5EKA A;  1OWG B;  1RIY A;  2NP2 A;  1OWG A; 
#chains in the Genus database with same CATH homology
 4FMR A;  4YEW C;  2HT0 B;  4YFT A;  1EXE A;  3RHI A;  4PT4 A;  2HT0 A;  2NDP A;  4YEY A;  1P78 A;  1P71 A;  5FBM A;  2O97 B;  4P3V A;  4DKY A;  4YF0 A;  4QJN A;  2O97 A;  4QJU A;  1B8Z A;  4N1V A;  2IIE A;  1P51 A;  4YEX A;  1OWF B;  2IIF A;  1HUE A;  4YFT C;  4YEW A;  1WTU A;  1MUL A;  1OUZ B;  5L8Z A;  1OWF A;  1IHF B;  4YFH A;  1OUZ A;  1HUU A;  1IHF A;  5EKA A;  1OWG B;  1RIY A;  2NP2 A;  1OWG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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