4PT4A

Crystal structure analysis of n terminal region containing the dimerization domain and dna binding domain of hu protein(histone like protein-dna binding) from mycobacterium tuberculosis [h37rv]
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
99
structure length
99
Chain Sequence
MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFRPGAQFKAVVSGAQRLPAEG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors
pubmed doi rcsb
molecule keywords DNA-binding protein HU homolog
molecule tags Dna binding protein
source organism Mycobacterium tuberculosis
total genus 25
structure length 99
sequence length 99
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00216 Bac_DNA_binding Bacterial DNA-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.520.10 Few Secondary Structures Irregular HU Protein; Chain A IHF-like DNA-binding proteins 4pt4A00
4QJUA 2IIEA 4YEXA 4DKYA 1MULA 4P3VA 1OUZB 4FMRA 5L8ZA 1IHFB 1EXEA 1B8ZA 1P71A 1RIYA 4YFTC 2O97B 1HUEA 1OWFA 4PT4A 1OWGB 3RHIA 5EKAA 2IIFA 1OUZA 4YEWA 1P51A 1IHFA 4YFHA 5FBMA 2HT0B 2O97A 1WTUA 4YEWC 2NDPA 1HUUA 1OWGA 2NP2A 4N1VA 4YEYA 1P78A 1OWFB 4YF0A 4YFTA 4QJNA 2HT0A
chains in the Genus database with same CATH superfamily
4QJUA 2IIEA 4YEXA 4DKYA 1MULA 4P3VA 1OUZB 4FMRA 5L8ZA 1IHFB 1EXEA 1B8ZA 1P71A 1RIYA 4YFTC 2O97B 1HUEA 1OWFA 4PT4A 1OWGB 3RHIA 5EKAA 2IIFA 1OUZA 4YEWA 1P51A 1IHFA 4YFHA 5FBMA 2HT0B 2O97A 1WTUA 4YEWC 2NDPA 1HUUA 1OWGA 2NP2A 4N1VA 4YEYA 1P78A 1OWFB 4YF0A 4YFTA 4QJNA 2HT0A
chains in the Genus database with same CATH topology
4QJUA 2IIEA 4YEXA 4DKYA 1MULA 4P3VA 1OUZB 4FMRA 5L8ZA 1IHFB 1EXEA 1B8ZA 1P71A 1RIYA 4YFTC 2O97B 1HUEA 1OWFA 4PT4A 1OWGB 3RHIA 5EKAA 2IIFA 1OUZA 4YEWA 1P51A 1IHFA 4YFHA 5FBMA 2HT0B 2O97A 1WTUA 4YEWC 2NDPA 1HUUA 1OWGA 2NP2A 4N1VA 4YEYA 1P78A 1OWFB 4YF0A 4YFTA 4QJNA 2HT0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QJU A;  2IIE A;  4YEX A;  4DKY A;  1MUL A;  4P3V A;  1OUZ B;  4FMR A;  5L8Z A;  1IHF B;  1EXE A;  1B8Z A;  1P71 A;  1RIY A;  4YFT C;  2O97 B;  1HUE A;  1OWF A;  4PT4 A;  1OWG B;  3RHI A;  5EKA A;  2IIF A;  1OUZ A;  4YEW A;  1P51 A;  1IHF A;  4YFH A;  5FBM A;  2HT0 B;  2O97 A;  1WTU A;  4YEW C;  2NDP A;  1HUU A;  1OWG A;  2NP2 A;  4N1V A;  4YEY A;  1P78 A;  1OWF B;  4YF0 A;  4YFT A;  4QJN A;  2HT0 A; 
#chains in the Genus database with same CATH topology
 4QJU A;  2IIE A;  4YEX A;  4DKY A;  1MUL A;  4P3V A;  1OUZ B;  4FMR A;  5L8Z A;  1IHF B;  1EXE A;  1B8Z A;  1P71 A;  1RIY A;  4YFT C;  2O97 B;  1HUE A;  1OWF A;  4PT4 A;  1OWG B;  3RHI A;  5EKA A;  2IIF A;  1OUZ A;  4YEW A;  1P51 A;  1IHF A;  4YFH A;  5FBM A;  2HT0 B;  2O97 A;  1WTU A;  4YEW C;  2NDP A;  1HUU A;  1OWG A;  2NP2 A;  4N1V A;  4YEY A;  1P78 A;  1OWF B;  4YF0 A;  4YFT A;  4QJN A;  2HT0 A; 
#chains in the Genus database with same CATH homology
 4QJU A;  2IIE A;  4YEX A;  4DKY A;  1MUL A;  4P3V A;  1OUZ B;  4FMR A;  5L8Z A;  1IHF B;  1EXE A;  1B8Z A;  1P71 A;  1RIY A;  4YFT C;  2O97 B;  1HUE A;  1OWF A;  4PT4 A;  1OWG B;  3RHI A;  5EKA A;  2IIF A;  1OUZ A;  4YEW A;  1P51 A;  1IHF A;  4YFH A;  5FBM A;  2HT0 B;  2O97 A;  1WTU A;  4YEW C;  2NDP A;  1HUU A;  1OWG A;  2NP2 A;  4N1V A;  4YEY A;  1P78 A;  1OWF B;  4YF0 A;  4YFT A;  4QJN A;  2HT0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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