4PT4A

Crystal structure analysis of n terminal region containing the dimerization domain and dna binding domain of hu protein(histone like protein-dna binding) from mycobacterium tuberculosis [h37rv]
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
99
structure length
99
Chain Sequence
MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFRPGAQFKAVVSGAQRLPAEG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors
pubmed doi rcsb
molecule keywords DNA-binding protein HU homolog
molecule tags Dna binding protein
source organism Mycobacterium tuberculosis
total genus 25
structure length 99
sequence length 99
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00216 Bac_DNA_binding Bacterial DNA-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.520.10 Few Secondary Structures Irregular HU Protein; Chain A IHF-like DNA-binding proteins 4pt4A00
4DKYA 1IHFA 1OWGA 4YFHA 2NP2A 2O97B 2IIFA 1P51A 5FBMA 1OWFA 4FMRA 1EXEA 5L8ZA 3RHIA 4YEWA 1IHFB 4PT4A 1WTUA 1P78A 2NDPA 4YEXA 1B8ZA 1OWGB 1P71A 5EKAA 4YFTA 1HUEA 1OWFB 1MULA 1OUZA 4YEYA 4P3VA 1HUUA 2HT0A 2IIEA 4QJNA 4YEWC 4YF0A 1OUZB 4N1VA 1RIYA 2O97A 4YFTC 4QJUA 2HT0B
chains in the Genus database with same CATH superfamily
4DKYA 1IHFA 1OWGA 4YFHA 2NP2A 2O97B 2IIFA 1P51A 5FBMA 1OWFA 4FMRA 1EXEA 5L8ZA 3RHIA 4YEWA 1IHFB 4PT4A 1WTUA 1P78A 2NDPA 4YEXA 1B8ZA 1OWGB 1P71A 5EKAA 4YFTA 1HUEA 1OWFB 1MULA 1OUZA 4YEYA 4P3VA 1HUUA 2HT0A 2IIEA 4QJNA 4YEWC 4YF0A 1OUZB 4N1VA 1RIYA 2O97A 4YFTC 4QJUA 2HT0B
chains in the Genus database with same CATH topology
4DKYA 1IHFA 1OWGA 4YFHA 2NP2A 2O97B 2IIFA 1P51A 5FBMA 1OWFA 4FMRA 1EXEA 5L8ZA 3RHIA 4YEWA 1IHFB 4PT4A 1WTUA 1P78A 2NDPA 4YEXA 1B8ZA 1OWGB 1P71A 5EKAA 4YFTA 1HUEA 1OWFB 1MULA 1OUZA 4YEYA 4P3VA 1HUUA 2HT0A 2IIEA 4QJNA 4YEWC 4YF0A 1OUZB 4N1VA 1RIYA 2O97A 4YFTC 4QJUA 2HT0B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DKY A;  1IHF A;  1OWG A;  4YFH A;  2NP2 A;  2O97 B;  2IIF A;  1P51 A;  5FBM A;  1OWF A;  4FMR A;  1EXE A;  5L8Z A;  3RHI A;  4YEW A;  1IHF B;  4PT4 A;  1WTU A;  1P78 A;  2NDP A;  4YEX A;  1B8Z A;  1OWG B;  1P71 A;  5EKA A;  4YFT A;  1HUE A;  1OWF B;  1MUL A;  1OUZ A;  4YEY A;  4P3V A;  1HUU A;  2HT0 A;  2IIE A;  4QJN A;  4YEW C;  4YF0 A;  1OUZ B;  4N1V A;  1RIY A;  2O97 A;  4YFT C;  4QJU A;  2HT0 B; 
#chains in the Genus database with same CATH topology
 4DKY A;  1IHF A;  1OWG A;  4YFH A;  2NP2 A;  2O97 B;  2IIF A;  1P51 A;  5FBM A;  1OWF A;  4FMR A;  1EXE A;  5L8Z A;  3RHI A;  4YEW A;  1IHF B;  4PT4 A;  1WTU A;  1P78 A;  2NDP A;  4YEX A;  1B8Z A;  1OWG B;  1P71 A;  5EKA A;  4YFT A;  1HUE A;  1OWF B;  1MUL A;  1OUZ A;  4YEY A;  4P3V A;  1HUU A;  2HT0 A;  2IIE A;  4QJN A;  4YEW C;  4YF0 A;  1OUZ B;  4N1V A;  1RIY A;  2O97 A;  4YFT C;  4QJU A;  2HT0 B; 
#chains in the Genus database with same CATH homology
 4DKY A;  1IHF A;  1OWG A;  4YFH A;  2NP2 A;  2O97 B;  2IIF A;  1P51 A;  5FBM A;  1OWF A;  4FMR A;  1EXE A;  5L8Z A;  3RHI A;  4YEW A;  1IHF B;  4PT4 A;  1WTU A;  1P78 A;  2NDP A;  4YEX A;  1B8Z A;  1OWG B;  1P71 A;  5EKA A;  4YFT A;  1HUE A;  1OWF B;  1MUL A;  1OUZ A;  4YEY A;  4P3V A;  1HUU A;  2HT0 A;  2IIE A;  4QJN A;  4YEW C;  4YF0 A;  1OUZ B;  4N1V A;  1RIY A;  2O97 A;  4YFT C;  4QJU A;  2HT0 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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