4R4FA

Crystal structure of non-neutralizing, a32-like antibody 2.2c in complex with hiv-1 yu2 gp120
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
351
structure length
340
Chain Sequence
WKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVKLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTGGSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIVIRSENFTNNAKTIIVQLNESVVINCTRPNNDIRQAHCNLSKTQWENTLEQIAIKLKEQFGNNKTIIFNPSSGGDPEIVTHSFNCGGEFFYCNSTQLFTWNDTNTGRNITLPCRIKQIINMWQEVGKAMYAPPIRGQIRCSSNITGLLLTRDGGKDTNGTEIFRPGGGDMRDNWRSELYKYKVVKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
pubmed doi rcsb
molecule tags Viral protein/immune system/inhibitor
source organism Human immunodeficiency virus 1
molecule keywords HIV-1 Env gp120
total genus 82
structure length 340
sequence length 351
ec nomenclature
pdb deposition date 2014-08-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 4r4fA01
1GC1G 5KJRG 4XVTG 3FUSA 4DVWA 5F96G 4RFOG 4DKUA 3TGRA 4R4FA 2NY0A 4LSRG 4YFLE 4S1QG 4XNYG 5FECC 3IDXG 4OLWG 3SE9G 3SE8G 4LAJA 4YDLA 5TE4G 4DKQA 2NY1A 2NY6A 2BF1A 3IDYA 2NXZA 3JWDA 1RZKG 4OLXG 4DKPA 4R4NA 4XNZA 4RZ8A 2I5YG 2I60G 4DVVA 4YDIG 5T33G 4YE4G 4JZWA 4LSTG 4DVSA 5F4PA 4DKVA 2NXYA 4JB9G 5F9OG 1G9NG 4OM0G 1G9MG 3NGBA 4J6RG 4DKRA 4OLVG 2NY4A 4YDKG 4H8WG 3TIHA 4OLYG 3HI1G 4R2GA 4RX4E 5FA2A 4I54A 1YYMG 5TE7G 3LQAG 4JM2E 4JPWG 1RZJG 2QADA 5CAYG 4RWYA 4XMPG 4LSPG 5I9QA 4S1RG 3RJQA 4KA2A 4LSSG 5IGXG 5F4RA 4DVTA 4OLZG 4JKPG 4YDJG 5CD5A 4LSUG 3TGTA 4LSQG 4I53A 2NY5G 4XVSG 4JZZA 4P9HG 5TE6G 4JPVG 5F4LA 5F4UA 4S1SG 4JDTG 4LSVG 2B4CG 3TGQA 3TGSA 4OM1G 4OLUG 2NY3A 3U7YG 4DKOA 2NY7G 4DVRG 5F9WA 3JWOA 2NY2A 4DVXA 4K0AA 1YYLG 4RFNA
chains in the Genus database with same CATH superfamily
1GC1G 5KJRG 4XVTG 3FUSA 4DVWA 5F96G 4RFOG 4DKUA 3TGRA 4R4FA 2NY0A 4LSRG 4YFLE 4S1QG 4XNYG 5FECC 3IDXG 4OLWG 3SE9G 3SE8G 4LAJA 4YDLA 5TE4G 4DKQA 2NY1A 2NY6A 2BF1A 3IDYA 2NXZA 3JWDA 1RZKG 4OLXG 4DKPA 4R4NA 4XNZA 4RZ8A 2I5YG 2I60G 4DVVA 4YDIG 5T33G 4YE4G 4JZWA 4LSTG 4DVSA 5F4PA 4DKVA 2NXYA 4JB9G 5F9OG 1G9NG 4OM0G 1G9MG 3NGBA 4J6RG 4DKRA 4OLVG 2NY4A 4YDKG 4H8WG 3TIHA 4OLYG 3HI1G 4R2GA 4RX4E 5FA2A 4I54A 1YYMG 5TE7G 3LQAG 4JM2E 4JPWG 1RZJG 2QADA 5CAYG 4RWYA 4XMPG 4LSPG 5I9QA 4S1RG 3RJQA 4KA2A 4LSSG 5IGXG 5F4RA 4DVTA 4OLZG 4JKPG 4YDJG 5CD5A 4LSUG 3TGTA 4LSQG 4I53A 2NY5G 4XVSG 4JZZA 4P9HG 5TE6G 4JPVG 5F4LA 5F4UA 4S1SG 4JDTG 4LSVG 2B4CG 3TGQA 3TGSA 4OM1G 4OLUG 2NY3A 3U7YG 4DKOA 2NY7G 4DVRG 5F9WA 3JWOA 2NY2A 4DVXA 4K0AA 1YYLG 4RFNA
chains in the Genus database with same CATH topology
1GC1G 5KJRG 4XVTG 3FUSA 4DVWA 5F96G 4RFOG 4DKUA 3TGRA 4R4FA 2NY0A 4LSRG 4YFLE 4S1QG 4XNYG 5FECC 3IDXG 4OLWG 3SE9G 3SE8G 4LAJA 4YDLA 5TE4G 4DKQA 2NY1A 2NY6A 2BF1A 3IDYA 2NXZA 3JWDA 1RZKG 4OLXG 4DKPA 4R4NA 4XNZA 4RZ8A 2I5YG 2I60G 4DVVA 4YDIG 5T33G 4YE4G 4JZWA 4LSTG 4DVSA 5F4PA 4DKVA 2NXYA 4JB9G 5F9OG 1G9NG 4OM0G 1G9MG 3NGBA 4J6RG 4DKRA 4OLVG 2NY4A 4YDKG 4H8WG 3TIHA 4OLYG 3HI1G 4R2GA 4RX4E 5FA2A 4I54A 1YYMG 5TE7G 3LQAG 4JM2E 4JPWG 1RZJG 2QADA 5CAYG 4RWYA 4XMPG 4LSPG 5I9QA 4S1RG 3RJQA 4KA2A 4LSSG 5IGXG 5F4RA 4DVTA 4OLZG 4JKPG 4YDJG 5CD5A 4LSUG 3TGTA 4LSQG 4I53A 2NY5G 4XVSG 4JZZA 4P9HG 5TE6G 4JPVG 5F4LA 5F4UA 4S1SG 4JDTG 4LSVG 2B4CG 3TGQA 3TGSA 4OM1G 4OLUG 2NY3A 3U7YG 4DKOA 2NY7G 4DVRG 5F9WA 3JWOA 2NY2A 4DVXA 4K0AA 1YYLG 4RFNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GC1 G;  5KJR G;  4XVT G;  3FUS A;  4DVW A;  5F96 G;  4RFO G;  4DKU A;  3TGR A;  4R4F A;  2NY0 A;  4LSR G;  4YFL E;  4S1Q G;  4XNY G;  5FEC C;  3IDX G;  4OLW G;  3SE9 G;  3SE8 G;  4LAJ A;  4YDL A;  5TE4 G;  4DKQ A;  2NY1 A;  2NY6 A;  2BF1 A;  3IDY A;  2NXZ A;  3JWD A;  1RZK G;  4OLX G;  4DKP A;  4R4N A;  4XNZ A;  4RZ8 A;  2I5Y G;  2I60 G;  4DVV A;  4YDI G;  5T33 G;  4YE4 G;  4JZW A;  4LST G;  4DVS A;  5F4P A;  4DKV A;  2NXY A;  4JB9 G;  5F9O G;  1G9N G;  4OM0 G;  1G9M G;  3NGB A;  4J6R G;  4DKR A;  4OLV G;  2NY4 A;  4YDK G;  4H8W G;  3TIH A;  4OLY G;  3HI1 G;  4R2G A;  4RX4 E;  5FA2 A;  4I54 A;  1YYM G;  5TE7 G;  3LQA G;  4JM2 E;  4JPW G;  1RZJ G;  2QAD A;  5CAY G;  4RWY A;  4XMP G;  4LSP G;  5I9Q A;  4S1R G;  3RJQ A;  4KA2 A;  4LSS G;  5IGX G;  5F4R A;  4DVT A;  4OLZ G;  4JKP G;  4YDJ G;  5CD5 A;  4LSU G;  3TGT A;  4LSQ G;  4I53 A;  2NY5 G;  4XVS G;  4JZZ A;  4P9H G;  5TE6 G;  4JPV G;  5F4L A;  5F4U A;  4S1S G;  4JDT G;  4LSV G;  2B4C G;  3TGQ A;  3TGS A;  4OM1 G;  4OLU G;  2NY3 A;  3U7Y G;  4DKO A;  2NY7 G;  4DVR G;  5F9W A;  3JWO A;  2NY2 A;  4DVX A;  4K0A A;  1YYL G;  4RFN A; 
#chains in the Genus database with same CATH topology
 1GC1 G;  5KJR G;  4XVT G;  3FUS A;  4DVW A;  5F96 G;  4RFO G;  4DKU A;  3TGR A;  4R4F A;  2NY0 A;  4LSR G;  4YFL E;  4S1Q G;  4XNY G;  5FEC C;  3IDX G;  4OLW G;  3SE9 G;  3SE8 G;  4LAJ A;  4YDL A;  5TE4 G;  4DKQ A;  2NY1 A;  2NY6 A;  2BF1 A;  3IDY A;  2NXZ A;  3JWD A;  1RZK G;  4OLX G;  4DKP A;  4R4N A;  4XNZ A;  4RZ8 A;  2I5Y G;  2I60 G;  4DVV A;  4YDI G;  5T33 G;  4YE4 G;  4JZW A;  4LST G;  4DVS A;  5F4P A;  4DKV A;  2NXY A;  4JB9 G;  5F9O G;  1G9N G;  4OM0 G;  1G9M G;  3NGB A;  4J6R G;  4DKR A;  4OLV G;  2NY4 A;  4YDK G;  4H8W G;  3TIH A;  4OLY G;  3HI1 G;  4R2G A;  4RX4 E;  5FA2 A;  4I54 A;  1YYM G;  5TE7 G;  3LQA G;  4JM2 E;  4JPW G;  1RZJ G;  2QAD A;  5CAY G;  4RWY A;  4XMP G;  4LSP G;  5I9Q A;  4S1R G;  3RJQ A;  4KA2 A;  4LSS G;  5IGX G;  5F4R A;  4DVT A;  4OLZ G;  4JKP G;  4YDJ G;  5CD5 A;  4LSU G;  3TGT A;  4LSQ G;  4I53 A;  2NY5 G;  4XVS G;  4JZZ A;  4P9H G;  5TE6 G;  4JPV G;  5F4L A;  5F4U A;  4S1S G;  4JDT G;  4LSV G;  2B4C G;  3TGQ A;  3TGS A;  4OM1 G;  4OLU G;  2NY3 A;  3U7Y G;  4DKO A;  2NY7 G;  4DVR G;  5F9W A;  3JWO A;  2NY2 A;  4DVX A;  4K0A A;  1YYL G;  4RFN A; 
#chains in the Genus database with same CATH homology
 1GC1 G;  5KJR G;  4XVT G;  3FUS A;  4DVW A;  5F96 G;  4RFO G;  4DKU A;  3TGR A;  4R4F A;  2NY0 A;  4LSR G;  4YFL E;  4S1Q G;  4XNY G;  5FEC C;  3IDX G;  4OLW G;  3SE9 G;  3SE8 G;  4LAJ A;  4YDL A;  5TE4 G;  4DKQ A;  2NY1 A;  2NY6 A;  2BF1 A;  3IDY A;  2NXZ A;  3JWD A;  1RZK G;  4OLX G;  4DKP A;  4R4N A;  4XNZ A;  4RZ8 A;  2I5Y G;  2I60 G;  4DVV A;  4YDI G;  5T33 G;  4YE4 G;  4JZW A;  4LST G;  4DVS A;  5F4P A;  4DKV A;  2NXY A;  4JB9 G;  5F9O G;  1G9N G;  4OM0 G;  1G9M G;  3NGB A;  4J6R G;  4DKR A;  4OLV G;  2NY4 A;  4YDK G;  4H8W G;  3TIH A;  4OLY G;  3HI1 G;  4R2G A;  4RX4 E;  5FA2 A;  4I54 A;  1YYM G;  5TE7 G;  3LQA G;  4JM2 E;  4JPW G;  1RZJ G;  2QAD A;  5CAY G;  4RWY A;  4XMP G;  4LSP G;  5I9Q A;  4S1R G;  3RJQ A;  4KA2 A;  4LSS G;  5IGX G;  5F4R A;  4DVT A;  4OLZ G;  4JKP G;  4YDJ G;  5CD5 A;  4LSU G;  3TGT A;  4LSQ G;  4I53 A;  2NY5 G;  4XVS G;  4JZZ A;  4P9H G;  5TE6 G;  4JPV G;  5F4L A;  5F4U A;  4S1S G;  4JDT G;  4LSV G;  2B4C G;  3TGQ A;  3TGS A;  4OM1 G;  4OLU G;  2NY3 A;  3U7Y G;  4DKO A;  2NY7 G;  4DVR G;  5F9W A;  3JWO A;  2NY2 A;  4DVX A;  4K0A A;  1YYL G;  4RFN A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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