4RDNA

Structure of yth-ythdf2 in complex with m6a
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
149
structure length
149
Chain Sequence
ENLYFQHMKHGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords YTH domain-containing family protein 2
total genus 42
structure length 149
sequence length 149
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04146 YTH YT521-B-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.590.10 Alpha Beta Roll ph1033 like fold ph1033 like domains 4rdnA00
4RDNA 4RCJA 2ZBNA 5J3EA 5DNOA 4RDOA 1WMMA 2AR1A 4RCIA 1ZCEA 2P5DA 2YU6A 2G2XA 3EOPA 4RCMA 4U8TA 2HD9A 4WQNA 2EVEA 2YUDA 2GBSA
chains in the Genus database with same CATH superfamily
4RDNA 4RCJA 2ZBNA 5J3EA 5DNOA 4RDOA 1WMMA 2AR1A 4RCIA 1ZCEA 2P5DA 2YU6A 2G2XA 3EOPA 4RCMA 4U8TA 2HD9A 4WQNA 2EVEA 2YUDA 2GBSA
chains in the Genus database with same CATH topology
4RDNA 4RCJA 2ZBNA 5J3EA 5DNOA 4RDOA 1WMMA 2AR1A 4RCIA 1ZCEA 2P5DA 2YU6A 2G2XA 3EOPA 4RCMA 4U8TA 2HD9A 4WQNA 2EVEA 2YUDA 2GBSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RDN A;  4RCJ A;  2ZBN A;  5J3E A;  5DNO A;  4RDO A;  1WMM A;  2AR1 A;  4RCI A;  1ZCE A;  2P5D A;  2YU6 A;  2G2X A;  3EOP A;  4RCM A;  4U8T A;  2HD9 A;  4WQN A;  2EVE A;  2YUD A;  2GBS A; 
#chains in the Genus database with same CATH topology
 4RDN A;  4RCJ A;  2ZBN A;  5J3E A;  5DNO A;  4RDO A;  1WMM A;  2AR1 A;  4RCI A;  1ZCE A;  2P5D A;  2YU6 A;  2G2X A;  3EOP A;  4RCM A;  4U8T A;  2HD9 A;  4WQN A;  2EVE A;  2YUD A;  2GBS A; 
#chains in the Genus database with same CATH homology
 4RDN A;  4RCJ A;  2ZBN A;  5J3E A;  5DNO A;  4RDO A;  1WMM A;  2AR1 A;  4RCI A;  1ZCE A;  2P5D A;  2YU6 A;  2G2X A;  3EOP A;  4RCM A;  4U8T A;  2HD9 A;  4WQN A;  2EVE A;  2YUD A;  2GBS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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