4RGDA

The structure a as-48 g13k/l40k mutant
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
70
structure length
70
Chain Sequence
MAKEFGIPAAVAKTVLNVVEAGGWVTTIVSILTAVGSGGKSLLAAAGRESIKAYLKKEIKKKGKRAVIAW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The bacteriocin AS-48 requires dimer dissociation followed by hydrophobic interactions with the membrane for antibacterial activity.
pubmed doi rcsb
molecule tags Antibiotic
source organism Enterococcus faecalis
molecule keywords Bacteriocin AS-48
total genus 26
structure length 70
sequence length 70
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-09-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09221 Bacteriocin_IId Bacteriocin class IId cyclical uberolysin-like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.225.10 Mainly Alpha Up-down Bundle Bacteriocin As-48; Chain A Bacteriocin AS-48 4rgdA00
1O83A 1E68A 2KJFA 2MP8A 1O84A 4RGDA 1O82A
chains in the Genus database with same CATH superfamily
4YCOA 1O83A 1E68A 2KSNA 4BF9A 4BFAA 2KJFA 2MP8A 1O84A 4RGDA 1O82A 4YCPA 3W9ZA
chains in the Genus database with same CATH topology
1O83A 1E68A 2KJFA 2MP8A 1O84A 4RGDA 1O82A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O83 A;  1E68 A;  2KJF A;  2MP8 A;  1O84 A;  4RGD A;  1O82 A; 
#chains in the Genus database with same CATH topology
 4YCO A;  1O83 A;  1E68 A;  2KSN A;  4BF9 A;  4BFA A;  2KJF A;  2MP8 A;  1O84 A;  4RGD A;  1O82 A;  4YCP A;  3W9Z A; 
#chains in the Genus database with same CATH homology
 1O83 A;  1E68 A;  2KJF A;  2MP8 A;  1O84 A;  4RGD A;  1O82 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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