4UECA

Complex of d. melanogaster eif4e with eif4g and cap analog
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
171
structure length
171
Chain Sequence
PHMKHPLMNVWTLWYLENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGRWVITLNKSSKTDLDNLWLDVLLCLIGEAFDHSDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNSLQYQLHKDTMV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
pubmed doi rcsb
molecule tags Translation
source organism Drosophila melanogaster
molecule keywords EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
total genus 45
structure length 171
sequence length 171
chains with identical sequence C
ec nomenclature
pdb deposition date 2014-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01652 IF4E Eukaryotic initiation factor 4E
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.760.10 Alpha Beta 2-Layer Sandwich RNA Cap, Translation Initiation Factor Eif4e RNA Cap, Translation Initiation Factor Eif4e 4uecA00
1EJ1A 3TF2A 4B6UA 3HXGA 4DT6A 1EJ4A 2IDVA 4AZAA 3M94A 4UEBA 5ABVA 3M93A 5EKVA 1L8BA 2Q4KA 2V8WA 1AP8A 2GPQA 2V8YA 5EHCA 5ABYA 5GW6A 5T46A 3U7XA 4AXGA 1EJHA 1WKWA 2V8XA 3AM7A 4TQBA 5T48A 3HXIA 1IPBA 2WMCA 4UECA 4B6VA 5ABXA 4UE9A 5ABUA 4TQCA 4UE8A 5T47A 5EIRA 2W97A 2W97B 1ZTPA 4BEAA 1IPCA 2JGCA 5BXVA 5EI3A 2IDRA 4UEAA 4DUMA 4UEDA 1RF8A 4TPWA 2JGBA
chains in the Genus database with same CATH superfamily
1EJ1A 3TF2A 4B6UA 3HXGA 4DT6A 1EJ4A 2IDVA 4AZAA 3M94A 4UEBA 5ABVA 3M93A 5EKVA 1L8BA 2Q4KA 2V8WA 1AP8A 2GPQA 2V8YA 5EHCA 5ABYA 5GW6A 5T46A 3U7XA 4AXGA 1EJHA 1WKWA 2V8XA 3AM7A 4TQBA 5T48A 3HXIA 1IPBA 2WMCA 4UECA 4B6VA 5ABXA 4UE9A 5ABUA 4TQCA 4UE8A 5T47A 5EIRA 2W97A 2W97B 1ZTPA 4BEAA 1IPCA 2JGCA 5BXVA 5EI3A 2IDRA 4UEAA 4DUMA 4UEDA 1RF8A 4TPWA 2JGBA
chains in the Genus database with same CATH topology
1EJ1A 3TF2A 4B6UA 3HXGA 4DT6A 1EJ4A 2IDVA 4AZAA 3M94A 4UEBA 5ABVA 3M93A 5EKVA 1L8BA 2Q4KA 2V8WA 1AP8A 2GPQA 2V8YA 5EHCA 5ABYA 5GW6A 5T46A 3U7XA 4AXGA 1EJHA 1WKWA 2V8XA 3AM7A 4TQBA 5T48A 3HXIA 1IPBA 2WMCA 4UECA 4B6VA 5ABXA 4UE9A 5ABUA 4TQCA 4UE8A 5T47A 5EIRA 2W97A 2W97B 1ZTPA 4BEAA 1IPCA 2JGCA 5BXVA 5EI3A 2IDRA 4UEAA 4DUMA 4UEDA 1RF8A 4TPWA 2JGBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EJ1 A;  3TF2 A;  4B6U A;  3HXG A;  4DT6 A;  1EJ4 A;  2IDV A;  4AZA A;  3M94 A;  4UEB A;  5ABV A;  3M93 A;  5EKV A;  1L8B A;  2Q4K A;  2V8W A;  1AP8 A;  2GPQ A;  2V8Y A;  5EHC A;  5ABY A;  5GW6 A;  5T46 A;  3U7X A;  4AXG A;  1EJH A;  1WKW A;  2V8X A;  3AM7 A;  4TQB A;  5T48 A;  3HXI A;  1IPB A;  2WMC A;  4UEC A;  4B6V A;  5ABX A;  4UE9 A;  5ABU A;  4TQC A;  4UE8 A;  5T47 A;  5EIR A;  2W97 A;  2W97 B;  1ZTP A;  4BEA A;  1IPC A;  2JGC A;  5BXV A;  5EI3 A;  2IDR A;  4UEA A;  4DUM A;  4UED A;  1RF8 A;  4TPW A;  2JGB A; 
#chains in the Genus database with same CATH topology
 1EJ1 A;  3TF2 A;  4B6U A;  3HXG A;  4DT6 A;  1EJ4 A;  2IDV A;  4AZA A;  3M94 A;  4UEB A;  5ABV A;  3M93 A;  5EKV A;  1L8B A;  2Q4K A;  2V8W A;  1AP8 A;  2GPQ A;  2V8Y A;  5EHC A;  5ABY A;  5GW6 A;  5T46 A;  3U7X A;  4AXG A;  1EJH A;  1WKW A;  2V8X A;  3AM7 A;  4TQB A;  5T48 A;  3HXI A;  1IPB A;  2WMC A;  4UEC A;  4B6V A;  5ABX A;  4UE9 A;  5ABU A;  4TQC A;  4UE8 A;  5T47 A;  5EIR A;  2W97 A;  2W97 B;  1ZTP A;  4BEA A;  1IPC A;  2JGC A;  5BXV A;  5EI3 A;  2IDR A;  4UEA A;  4DUM A;  4UED A;  1RF8 A;  4TPW A;  2JGB A; 
#chains in the Genus database with same CATH homology
 1EJ1 A;  3TF2 A;  4B6U A;  3HXG A;  4DT6 A;  1EJ4 A;  2IDV A;  4AZA A;  3M94 A;  4UEB A;  5ABV A;  3M93 A;  5EKV A;  1L8B A;  2Q4K A;  2V8W A;  1AP8 A;  2GPQ A;  2V8Y A;  5EHC A;  5ABY A;  5GW6 A;  5T46 A;  3U7X A;  4AXG A;  1EJH A;  1WKW A;  2V8X A;  3AM7 A;  4TQB A;  5T48 A;  3HXI A;  1IPB A;  2WMC A;  4UEC A;  4B6V A;  5ABX A;  4UE9 A;  5ABU A;  4TQC A;  4UE8 A;  5T47 A;  5EIR A;  2W97 A;  2W97 B;  1ZTP A;  4BEA A;  1IPC A;  2JGC A;  5BXV A;  5EI3 A;  2IDR A;  4UEA A;  4DUM A;  4UED A;  1RF8 A;  4TPW A;  2JGB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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