4UY1A

Novel pyrazole series of group x secretory phospholipase a2 (spla2-x) inhibitors
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
122
structure length
122
Chain Sequence
GILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of a Novel Pyrazole Series of Group X Secreted Phospholipase A2 Inhibitor (Spla2X) Via Fragment Based Virtual Screening
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords GROUP 10 SECRETORY PHOSPHOLIPASE A2
total genus 40
structure length 122
sequence length 122
chains with identical sequence B
ec nomenclature ec 3.1.1.4: Phospholipase A(2).
pdb deposition date 2014-08-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00068 Phospholip_A2_1 Phospholipase A2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.90.10 Mainly Alpha Up-down Bundle Phospholipase A2 Phospholipase A2 domain 4uy1A00
5P2PA 2OYFA 3V9MA 2QOGB 3G8HA 1Q5TA 1TP2A 1IRBA 3H1XA 1MKTA 1MKUA 4K06A 2ZP5A 1JQ9A 2WQ5A 1BP2A 1VPIA 4YU7A 1G0ZA 3BJWA 1JLTB 2H8IA 1OYFA 1GH4A 1YXHA 1VAPA 4QF7A 1KQUA 1P2PA 1PC9A 1CEHA 3JQLA 1DPYA 2B96A 4NTXC 1BBCA 2B03A 2GNSA 2OTFA 2PMJA 1S6BB 1PIRA 3HZDA 1AOKB 2PWSA 1BJJA 1MH2A 1PISA 2QOGA 3G8FA 4QF8A 1O2EA 1ZLBA 1DB4A 3VBZA 1FV0A 3U8HA 1SV3A 1Y75B 1SKGA 1TJ9A 2QU9A 1GP7A 2AZZA 1P7OA 1ZM6A 1IT4A 2B00A 3I3IA 4YZ7A 2B01A 1CLPA 1L8SA 1TK4A 1JLTA 1OXLA 1PP2L 1OQSA 1B4WA 1KVWA 1Z76A 2Q1PA 2ARMA 3BP2A 1J1AA 3FG5A 1C1JA 4E4CA 2QHEA 1Y6OA 2I0UA 1MKSA 1M8SA 1S8HA 1TGMA 4BP2A 2PVTA 3CXIA 1ZL7A 1YXLA 2ZP3A 1KVOA 4FGAA 1UNEA 1Y38A 4HG9A 1TG4A 1CL5A 4K09A 1KVYA 1Y4LA 2RD4B 1OXRA 2OSNA 1IJLA 2FNXA 5G3NA 1MC2A 1BUNA 2BCHA 1DB5A 3L30A 1TD7A 1LE6A 2QUEA 3GCIA 3OSHA 1UMVX 3P2PA 4NTYC 1AYPA 1OZ6A 1BPQA 2AOZA 1DCYA 1A2AA 1N28A 1Q6VA 1ZWPA 1FAZA 1TG1A 1SXKA 1MH7A 1XXWB 3JQ5A 2H4CB 2ZP4A 2PB8A 1ZYXA 1IT5A 4UY1A 3O4MA 1Y6PA 4KF3A 1G2XA 1FB2A 4P2PA 1MG6A 1LWBA 1C74A 4NTWC 1SFVA 2Q2JA 1TC8A 1KP4A 1OYFB 3JR8A 2OUBA 4RFPA 3T0RA 1S6BA 1POCA 3I3HA 1SFWA 1OWSB 1AOKA 1VIPA 2G58A 1PO8A 1SZ8A 4O1YA 2OK9A 2OSHA 4QEMA 3MLMA 2BP2A 1SV9A 1POBA 2WG8B 3FVJA 3FO7A 1Y75A 3G8GA 3FVIA 1XXWA 2H4CA 1S8IA 1MH2B 1KPMA 4DBKA 2QHDA 4GLDA 3UX7A 4QERA 1FXFA 3IQ3A 1PSHA 1Q7AA 3U8DA 1U4JA 2PH4A 1HN4A 1U73A 4G5IA 1XXSA 4WTBA 1LN8A 1N29A 3HZWA 1OQSB 2AZYA 3QNLA 3CYLA 2DPZA 1OWSA 3R0LD 2QVDA 1GODA 3I03A 4QGDA 2WG9A 3U8IA 1FDKA 3CBIA 2WG7A 2RD4A 4EIXA 2PHIA 1TJKA 2WG8A 4GFYA 1BK9A 2OQDA 3ELOA 3NJUA 2QHWA 4H0SA 2OTHA 1O3WA 1PWOA 1A3FA 1TDVA 1MKVA 1PPAA 3DIHA 2DO2A 1POEA 2B17A 1JQ8A 1SQZA 2NOTA 1VKQA 4HMBA 1PODA 2B04A 1BVMA 1FX9A 1FE5A 1M8RA 3QLMA 1AE7A 1VL9A 1POAA 1JIAA 1PA0A 1ZR8A 3JTIA 5G3MA 4DCFA 1MF4A 1S8GA 3VC0A 3HSWA 1TH6A 1MH8A 1PSJA 1G4IA 1LE7A 1QLLA 2O1NA 2BD1A 4YV5A 3U8BA 4AUPA 2PYCA 1GMZA 1KVXA 2BAXA 2ZBHA 1OZYA 3Q4YA 4QMCA 2OLIA 1M8TA 1T37A 1RGBA 1A3DA 2BPPA
chains in the Genus database with same CATH superfamily
5P2PA 2OYFA 3V9MA 2QOGB 3G8HA 1Q5TA 1TP2A 1IRBA 3H1XA 1MKTA 1MKUA 4K06A 2ZP5A 1JQ9A 2WQ5A 1BP2A 1VPIA 4YU7A 1G0ZA 3BJWA 1JLTB 2H8IA 1OYFA 1GH4A 1YXHA 1VAPA 4QF7A 1KQUA 1P2PA 1PC9A 1CEHA 3JQLA 1DPYA 2B96A 4NTXC 1BBCA 2B03A 2GNSA 2OTFA 2PMJA 1S6BB 1PIRA 3HZDA 1AOKB 2PWSA 1BJJA 1MH2A 1PISA 2QOGA 3G8FA 4QF8A 1O2EA 1ZLBA 1DB4A 3VBZA 1FV0A 3U8HA 1SV3A 1Y75B 1SKGA 1TJ9A 2QU9A 1GP7A 2AZZA 1P7OA 1ZM6A 1IT4A 2B00A 3I3IA 4YZ7A 2B01A 1CLPA 1L8SA 1TK4A 1JLTA 1OXLA 1PP2L 1OQSA 1B4WA 1KVWA 1Z76A 2Q1PA 2ARMA 3BP2A 1J1AA 3FG5A 1C1JA 4E4CA 2QHEA 1Y6OA 2I0UA 1MKSA 1M8SA 1S8HA 1TGMA 4BP2A 2PVTA 3CXIA 1ZL7A 1YXLA 2ZP3A 1KVOA 4FGAA 1UNEA 1Y38A 4HG9A 1TG4A 1CL5A 4K09A 1KVYA 1Y4LA 2RD4B 1OXRA 2OSNA 1IJLA 2FNXA 5G3NA 1MC2A 1BUNA 2BCHA 1DB5A 3L30A 1TD7A 1LE6A 2QUEA 3GCIA 3OSHA 1UMVX 3P2PA 4NTYC 1AYPA 1OZ6A 1BPQA 2AOZA 1DCYA 1A2AA 1N28A 1Q6VA 1ZWPA 1FAZA 1TG1A 1SXKA 1MH7A 1XXWB 3JQ5A 2H4CB 2ZP4A 2PB8A 1ZYXA 1IT5A 4UY1A 3O4MA 1Y6PA 4KF3A 1G2XA 1FB2A 4P2PA 1MG6A 1LWBA 1C74A 4NTWC 1SFVA 2Q2JA 1TC8A 1KP4A 1OYFB 3JR8A 2OUBA 4RFPA 3T0RA 1S6BA 1POCA 3I3HA 1SFWA 1OWSB 1AOKA 1VIPA 2G58A 1PO8A 1SZ8A 4O1YA 2OK9A 2OSHA 4QEMA 3MLMA 2BP2A 1SV9A 1POBA 2WG8B 3FVJA 3FO7A 1Y75A 3G8GA 3FVIA 1XXWA 2H4CA 1S8IA 1MH2B 1KPMA 4DBKA 2QHDA 4GLDA 3UX7A 4QERA 1FXFA 3IQ3A 1PSHA 1Q7AA 3U8DA 1U4JA 2PH4A 1HN4A 1U73A 4G5IA 1XXSA 4WTBA 1LN8A 1N29A 3HZWA 1OQSB 2AZYA 3QNLA 3CYLA 2DPZA 1OWSA 3R0LD 2QVDA 1GODA 3I03A 4QGDA 2WG9A 3U8IA 1FDKA 3CBIA 2WG7A 2RD4A 4EIXA 2PHIA 1TJKA 2WG8A 4GFYA 1BK9A 2OQDA 3ELOA 3NJUA 2QHWA 4H0SA 2OTHA 1O3WA 1PWOA 1A3FA 1TDVA 1MKVA 1PPAA 3DIHA 2DO2A 1POEA 2B17A 1JQ8A 1SQZA 2NOTA 1VKQA 4HMBA 1PODA 2B04A 1BVMA 1FX9A 1FE5A 1M8RA 3QLMA 1AE7A 1VL9A 1POAA 1JIAA 1PA0A 1ZR8A 3JTIA 5G3MA 4DCFA 1MF4A 1S8GA 3VC0A 3HSWA 1TH6A 1MH8A 1PSJA 1G4IA 1LE7A 1QLLA 2O1NA 2BD1A 4YV5A 3U8BA 4AUPA 2PYCA 1GMZA 1KVXA 2BAXA 2ZBHA 1OZYA 3Q4YA 4QMCA 2OLIA 1M8TA 1T37A 1RGBA 1A3DA 2BPPA
chains in the Genus database with same CATH topology
5P2PA 2OYFA 3V9MA 2QOGB 3G8HA 1Q5TA 1TP2A 1IRBA 3H1XA 1MKTA 1MKUA 4K06A 2ZP5A 1JQ9A 2WQ5A 1BP2A 1VPIA 4YU7A 1G0ZA 3BJWA 1JLTB 2H8IA 1OYFA 1GH4A 1YXHA 1VAPA 4QF7A 1KQUA 1P2PA 1PC9A 1CEHA 3JQLA 1DPYA 2B96A 4NTXC 1BBCA 2B03A 2GNSA 2OTFA 2PMJA 1S6BB 1PIRA 3HZDA 1AOKB 2PWSA 1BJJA 1MH2A 1PISA 2QOGA 3G8FA 4QF8A 1O2EA 1ZLBA 1DB4A 3VBZA 1FV0A 3U8HA 1SV3A 1Y75B 1SKGA 1TJ9A 2QU9A 1GP7A 2AZZA 1P7OA 1ZM6A 1IT4A 2B00A 3I3IA 4YZ7A 2B01A 1CLPA 1L8SA 1TK4A 1JLTA 1OXLA 1PP2L 1OQSA 1B4WA 1KVWA 1Z76A 2Q1PA 2ARMA 3BP2A 1J1AA 3FG5A 1C1JA 4E4CA 2QHEA 1Y6OA 2I0UA 1MKSA 1M8SA 1S8HA 1TGMA 4BP2A 2PVTA 3CXIA 1ZL7A 1YXLA 2ZP3A 1KVOA 4FGAA 1UNEA 1Y38A 4HG9A 1TG4A 1CL5A 4K09A 1KVYA 1Y4LA 2RD4B 1OXRA 2OSNA 1IJLA 2FNXA 5G3NA 1MC2A 1BUNA 2BCHA 1DB5A 3L30A 1TD7A 1LE6A 2QUEA 3GCIA 3OSHA 1UMVX 3P2PA 4NTYC 1AYPA 1OZ6A 1BPQA 2AOZA 1DCYA 1A2AA 1N28A 1Q6VA 1ZWPA 1FAZA 1TG1A 1SXKA 1MH7A 1XXWB 3JQ5A 2H4CB 2ZP4A 2PB8A 1ZYXA 1IT5A 4UY1A 3O4MA 1Y6PA 4KF3A 1G2XA 1FB2A 4P2PA 1MG6A 1LWBA 1C74A 4NTWC 1SFVA 2Q2JA 1TC8A 1KP4A 1OYFB 3JR8A 2OUBA 4RFPA 3T0RA 1S6BA 1POCA 3I3HA 1SFWA 1OWSB 1AOKA 1VIPA 2G58A 1PO8A 1SZ8A 4O1YA 2OK9A 2OSHA 4QEMA 3MLMA 2BP2A 1SV9A 1POBA 2WG8B 3FVJA 3FO7A 1Y75A 3G8GA 3FVIA 1XXWA 2H4CA 1S8IA 1MH2B 1KPMA 4DBKA 2QHDA 4GLDA 3UX7A 4QERA 1FXFA 3IQ3A 1PSHA 1Q7AA 3U8DA 1U4JA 2PH4A 1HN4A 1U73A 4G5IA 1XXSA 4WTBA 1LN8A 1N29A 3HZWA 1OQSB 2AZYA 3QNLA 3CYLA 2DPZA 1OWSA 3R0LD 2QVDA 1GODA 3I03A 4QGDA 2WG9A 3U8IA 1FDKA 3CBIA 2WG7A 2RD4A 4EIXA 2PHIA 1TJKA 2WG8A 4GFYA 1BK9A 2OQDA 3ELOA 3NJUA 2QHWA 4H0SA 2OTHA 1O3WA 1PWOA 1A3FA 1TDVA 1MKVA 1PPAA 3DIHA 2DO2A 1POEA 2B17A 1JQ8A 1SQZA 2NOTA 1VKQA 4HMBA 1PODA 2B04A 1BVMA 1FX9A 1FE5A 1M8RA 3QLMA 1AE7A 1VL9A 1POAA 1JIAA 1PA0A 1ZR8A 3JTIA 5G3MA 4DCFA 1MF4A 1S8GA 3VC0A 3HSWA 1TH6A 1MH8A 1PSJA 1G4IA 1LE7A 1QLLA 2O1NA 2BD1A 4YV5A 3U8BA 4AUPA 2PYCA 1GMZA 1KVXA 2BAXA 2ZBHA 1OZYA 3Q4YA 4QMCA 2OLIA 1M8TA 1T37A 1RGBA 1A3DA 2BPPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5P2P A;  2OYF A;  3V9M A;  2QOG B;  3G8H A;  1Q5T A;  1TP2 A;  1IRB A;  3H1X A;  1MKT A;  1MKU A;  4K06 A;  2ZP5 A;  1JQ9 A;  2WQ5 A;  1BP2 A;  1VPI A;  4YU7 A;  1G0Z A;  3BJW A;  1JLT B;  2H8I A;  1OYF A;  1GH4 A;  1YXH A;  1VAP A;  4QF7 A;  1KQU A;  1P2P A;  1PC9 A;  1CEH A;  3JQL A;  1DPY A;  2B96 A;  4NTX C;  1BBC A;  2B03 A;  2GNS A;  2OTF A;  2PMJ A;  1S6B B;  1PIR A;  3HZD A;  1AOK B;  2PWS A;  1BJJ A;  1MH2 A;  1PIS A;  2QOG A;  3G8F A;  4QF8 A;  1O2E A;  1ZLB A;  1DB4 A;  3VBZ A;  1FV0 A;  3U8H A;  1SV3 A;  1Y75 B;  1SKG A;  1TJ9 A;  2QU9 A;  1GP7 A;  2AZZ A;  1P7O A;  1ZM6 A;  1IT4 A;  2B00 A;  3I3I A;  4YZ7 A;  2B01 A;  1CLP A;  1L8S A;  1TK4 A;  1JLT A;  1OXL A;  1PP2 L;  1OQS A;  1B4W A;  1KVW A;  1Z76 A;  2Q1P A;  2ARM A;  3BP2 A;  1J1A A;  3FG5 A;  1C1J A;  4E4C A;  2QHE A;  1Y6O A;  2I0U A;  1MKS A;  1M8S A;  1S8H A;  1TGM A;  4BP2 A;  2PVT A;  3CXI A;  1ZL7 A;  1YXL A;  2ZP3 A;  1KVO A;  4FGA A;  1UNE A;  1Y38 A;  4HG9 A;  1TG4 A;  1CL5 A;  4K09 A;  1KVY A;  1Y4L A;  2RD4 B;  1OXR A;  2OSN A;  1IJL A;  2FNX A;  5G3N A;  1MC2 A;  1BUN A;  2BCH A;  1DB5 A;  3L30 A;  1TD7 A;  1LE6 A;  2QUE A;  3GCI A;  3OSH A;  1UMV X;  3P2P A;  4NTY C;  1AYP A;  1OZ6 A;  1BPQ A;  2AOZ A;  1DCY A;  1A2A A;  1N28 A;  1Q6V A;  1ZWP A;  1FAZ A;  1TG1 A;  1SXK A;  1MH7 A;  1XXW B;  3JQ5 A;  2H4C B;  2ZP4 A;  2PB8 A;  1ZYX A;  1IT5 A;  4UY1 A;  3O4M A;  1Y6P A;  4KF3 A;  1G2X A;  1FB2 A;  4P2P A;  1MG6 A;  1LWB A;  1C74 A;  4NTW C;  1SFV A;  2Q2J A;  1TC8 A;  1KP4 A;  1OYF B;  3JR8 A;  2OUB A;  4RFP A;  3T0R A;  1S6B A;  1POC A;  3I3H A;  1SFW A;  1OWS B;  1AOK A;  1VIP A;  2G58 A;  1PO8 A;  1SZ8 A;  4O1Y A;  2OK9 A;  2OSH A;  4QEM A;  3MLM A;  2BP2 A;  1SV9 A;  1POB A;  2WG8 B;  3FVJ A;  3FO7 A;  1Y75 A;  3G8G A;  3FVI A;  1XXW A;  2H4C A;  1S8I A;  1MH2 B;  1KPM A;  4DBK A;  2QHD A;  4GLD A;  3UX7 A;  4QER A;  1FXF A;  3IQ3 A;  1PSH A;  1Q7A A;  3U8D A;  1U4J A;  2PH4 A;  1HN4 A;  1U73 A;  4G5I A;  1XXS A;  4WTB A;  1LN8 A;  1N29 A;  3HZW A;  1OQS B;  2AZY A;  3QNL A;  3CYL A;  2DPZ A;  1OWS A;  3R0L D;  2QVD A;  1GOD A;  3I03 A;  4QGD A;  2WG9 A;  3U8I A;  1FDK A;  3CBI A;  2WG7 A;  2RD4 A;  4EIX A;  2PHI A;  1TJK A;  2WG8 A;  4GFY A;  1BK9 A;  2OQD A;  3ELO A;  3NJU A;  2QHW A;  4H0S A;  2OTH A;  1O3W A;  1PWO A;  1A3F A;  1TDV A;  1MKV A;  1PPA A;  3DIH A;  2DO2 A;  1POE A;  2B17 A;  1JQ8 A;  1SQZ A;  2NOT A;  1VKQ A;  4HMB A;  1POD A;  2B04 A;  1BVM A;  1FX9 A;  1FE5 A;  1M8R A;  3QLM A;  1AE7 A;  1VL9 A;  1POA A;  1JIA A;  1PA0 A;  1ZR8 A;  3JTI A;  5G3M A;  4DCF A;  1MF4 A;  1S8G A;  3VC0 A;  3HSW A;  1TH6 A;  1MH8 A;  1PSJ A;  1G4I A;  1LE7 A;  1QLL A;  2O1N A;  2BD1 A;  4YV5 A;  3U8B A;  4AUP A;  2PYC A;  1GMZ A;  1KVX A;  2BAX A;  2ZBH A;  1OZY A;  3Q4Y A;  4QMC A;  2OLI A;  1M8T A;  1T37 A;  1RGB A;  1A3D A;  2BPP A; 
#chains in the Genus database with same CATH topology
 5P2P A;  2OYF A;  3V9M A;  2QOG B;  3G8H A;  1Q5T A;  1TP2 A;  1IRB A;  3H1X A;  1MKT A;  1MKU A;  4K06 A;  2ZP5 A;  1JQ9 A;  2WQ5 A;  1BP2 A;  1VPI A;  4YU7 A;  1G0Z A;  3BJW A;  1JLT B;  2H8I A;  1OYF A;  1GH4 A;  1YXH A;  1VAP A;  4QF7 A;  1KQU A;  1P2P A;  1PC9 A;  1CEH A;  3JQL A;  1DPY A;  2B96 A;  4NTX C;  1BBC A;  2B03 A;  2GNS A;  2OTF A;  2PMJ A;  1S6B B;  1PIR A;  3HZD A;  1AOK B;  2PWS A;  1BJJ A;  1MH2 A;  1PIS A;  2QOG A;  3G8F A;  4QF8 A;  1O2E A;  1ZLB A;  1DB4 A;  3VBZ A;  1FV0 A;  3U8H A;  1SV3 A;  1Y75 B;  1SKG A;  1TJ9 A;  2QU9 A;  1GP7 A;  2AZZ A;  1P7O A;  1ZM6 A;  1IT4 A;  2B00 A;  3I3I A;  4YZ7 A;  2B01 A;  1CLP A;  1L8S A;  1TK4 A;  1JLT A;  1OXL A;  1PP2 L;  1OQS A;  1B4W A;  1KVW A;  1Z76 A;  2Q1P A;  2ARM A;  3BP2 A;  1J1A A;  3FG5 A;  1C1J A;  4E4C A;  2QHE A;  1Y6O A;  2I0U A;  1MKS A;  1M8S A;  1S8H A;  1TGM A;  4BP2 A;  2PVT A;  3CXI A;  1ZL7 A;  1YXL A;  2ZP3 A;  1KVO A;  4FGA A;  1UNE A;  1Y38 A;  4HG9 A;  1TG4 A;  1CL5 A;  4K09 A;  1KVY A;  1Y4L A;  2RD4 B;  1OXR A;  2OSN A;  1IJL A;  2FNX A;  5G3N A;  1MC2 A;  1BUN A;  2BCH A;  1DB5 A;  3L30 A;  1TD7 A;  1LE6 A;  2QUE A;  3GCI A;  3OSH A;  1UMV X;  3P2P A;  4NTY C;  1AYP A;  1OZ6 A;  1BPQ A;  2AOZ A;  1DCY A;  1A2A A;  1N28 A;  1Q6V A;  1ZWP A;  1FAZ A;  1TG1 A;  1SXK A;  1MH7 A;  1XXW B;  3JQ5 A;  2H4C B;  2ZP4 A;  2PB8 A;  1ZYX A;  1IT5 A;  4UY1 A;  3O4M A;  1Y6P A;  4KF3 A;  1G2X A;  1FB2 A;  4P2P A;  1MG6 A;  1LWB A;  1C74 A;  4NTW C;  1SFV A;  2Q2J A;  1TC8 A;  1KP4 A;  1OYF B;  3JR8 A;  2OUB A;  4RFP A;  3T0R A;  1S6B A;  1POC A;  3I3H A;  1SFW A;  1OWS B;  1AOK A;  1VIP A;  2G58 A;  1PO8 A;  1SZ8 A;  4O1Y A;  2OK9 A;  2OSH A;  4QEM A;  3MLM A;  2BP2 A;  1SV9 A;  1POB A;  2WG8 B;  3FVJ A;  3FO7 A;  1Y75 A;  3G8G A;  3FVI A;  1XXW A;  2H4C A;  1S8I A;  1MH2 B;  1KPM A;  4DBK A;  2QHD A;  4GLD A;  3UX7 A;  4QER A;  1FXF A;  3IQ3 A;  1PSH A;  1Q7A A;  3U8D A;  1U4J A;  2PH4 A;  1HN4 A;  1U73 A;  4G5I A;  1XXS A;  4WTB A;  1LN8 A;  1N29 A;  3HZW A;  1OQS B;  2AZY A;  3QNL A;  3CYL A;  2DPZ A;  1OWS A;  3R0L D;  2QVD A;  1GOD A;  3I03 A;  4QGD A;  2WG9 A;  3U8I A;  1FDK A;  3CBI A;  2WG7 A;  2RD4 A;  4EIX A;  2PHI A;  1TJK A;  2WG8 A;  4GFY A;  1BK9 A;  2OQD A;  3ELO A;  3NJU A;  2QHW A;  4H0S A;  2OTH A;  1O3W A;  1PWO A;  1A3F A;  1TDV A;  1MKV A;  1PPA A;  3DIH A;  2DO2 A;  1POE A;  2B17 A;  1JQ8 A;  1SQZ A;  2NOT A;  1VKQ A;  4HMB A;  1POD A;  2B04 A;  1BVM A;  1FX9 A;  1FE5 A;  1M8R A;  3QLM A;  1AE7 A;  1VL9 A;  1POA A;  1JIA A;  1PA0 A;  1ZR8 A;  3JTI A;  5G3M A;  4DCF A;  1MF4 A;  1S8G A;  3VC0 A;  3HSW A;  1TH6 A;  1MH8 A;  1PSJ A;  1G4I A;  1LE7 A;  1QLL A;  2O1N A;  2BD1 A;  4YV5 A;  3U8B A;  4AUP A;  2PYC A;  1GMZ A;  1KVX A;  2BAX A;  2ZBH A;  1OZY A;  3Q4Y A;  4QMC A;  2OLI A;  1M8T A;  1T37 A;  1RGB A;  1A3D A;  2BPP A; 
#chains in the Genus database with same CATH homology
 5P2P A;  2OYF A;  3V9M A;  2QOG B;  3G8H A;  1Q5T A;  1TP2 A;  1IRB A;  3H1X A;  1MKT A;  1MKU A;  4K06 A;  2ZP5 A;  1JQ9 A;  2WQ5 A;  1BP2 A;  1VPI A;  4YU7 A;  1G0Z A;  3BJW A;  1JLT B;  2H8I A;  1OYF A;  1GH4 A;  1YXH A;  1VAP A;  4QF7 A;  1KQU A;  1P2P A;  1PC9 A;  1CEH A;  3JQL A;  1DPY A;  2B96 A;  4NTX C;  1BBC A;  2B03 A;  2GNS A;  2OTF A;  2PMJ A;  1S6B B;  1PIR A;  3HZD A;  1AOK B;  2PWS A;  1BJJ A;  1MH2 A;  1PIS A;  2QOG A;  3G8F A;  4QF8 A;  1O2E A;  1ZLB A;  1DB4 A;  3VBZ A;  1FV0 A;  3U8H A;  1SV3 A;  1Y75 B;  1SKG A;  1TJ9 A;  2QU9 A;  1GP7 A;  2AZZ A;  1P7O A;  1ZM6 A;  1IT4 A;  2B00 A;  3I3I A;  4YZ7 A;  2B01 A;  1CLP A;  1L8S A;  1TK4 A;  1JLT A;  1OXL A;  1PP2 L;  1OQS A;  1B4W A;  1KVW A;  1Z76 A;  2Q1P A;  2ARM A;  3BP2 A;  1J1A A;  3FG5 A;  1C1J A;  4E4C A;  2QHE A;  1Y6O A;  2I0U A;  1MKS A;  1M8S A;  1S8H A;  1TGM A;  4BP2 A;  2PVT A;  3CXI A;  1ZL7 A;  1YXL A;  2ZP3 A;  1KVO A;  4FGA A;  1UNE A;  1Y38 A;  4HG9 A;  1TG4 A;  1CL5 A;  4K09 A;  1KVY A;  1Y4L A;  2RD4 B;  1OXR A;  2OSN A;  1IJL A;  2FNX A;  5G3N A;  1MC2 A;  1BUN A;  2BCH A;  1DB5 A;  3L30 A;  1TD7 A;  1LE6 A;  2QUE A;  3GCI A;  3OSH A;  1UMV X;  3P2P A;  4NTY C;  1AYP A;  1OZ6 A;  1BPQ A;  2AOZ A;  1DCY A;  1A2A A;  1N28 A;  1Q6V A;  1ZWP A;  1FAZ A;  1TG1 A;  1SXK A;  1MH7 A;  1XXW B;  3JQ5 A;  2H4C B;  2ZP4 A;  2PB8 A;  1ZYX A;  1IT5 A;  4UY1 A;  3O4M A;  1Y6P A;  4KF3 A;  1G2X A;  1FB2 A;  4P2P A;  1MG6 A;  1LWB A;  1C74 A;  4NTW C;  1SFV A;  2Q2J A;  1TC8 A;  1KP4 A;  1OYF B;  3JR8 A;  2OUB A;  4RFP A;  3T0R A;  1S6B A;  1POC A;  3I3H A;  1SFW A;  1OWS B;  1AOK A;  1VIP A;  2G58 A;  1PO8 A;  1SZ8 A;  4O1Y A;  2OK9 A;  2OSH A;  4QEM A;  3MLM A;  2BP2 A;  1SV9 A;  1POB A;  2WG8 B;  3FVJ A;  3FO7 A;  1Y75 A;  3G8G A;  3FVI A;  1XXW A;  2H4C A;  1S8I A;  1MH2 B;  1KPM A;  4DBK A;  2QHD A;  4GLD A;  3UX7 A;  4QER A;  1FXF A;  3IQ3 A;  1PSH A;  1Q7A A;  3U8D A;  1U4J A;  2PH4 A;  1HN4 A;  1U73 A;  4G5I A;  1XXS A;  4WTB A;  1LN8 A;  1N29 A;  3HZW A;  1OQS B;  2AZY A;  3QNL A;  3CYL A;  2DPZ A;  1OWS A;  3R0L D;  2QVD A;  1GOD A;  3I03 A;  4QGD A;  2WG9 A;  3U8I A;  1FDK A;  3CBI A;  2WG7 A;  2RD4 A;  4EIX A;  2PHI A;  1TJK A;  2WG8 A;  4GFY A;  1BK9 A;  2OQD A;  3ELO A;  3NJU A;  2QHW A;  4H0S A;  2OTH A;  1O3W A;  1PWO A;  1A3F A;  1TDV A;  1MKV A;  1PPA A;  3DIH A;  2DO2 A;  1POE A;  2B17 A;  1JQ8 A;  1SQZ A;  2NOT A;  1VKQ A;  4HMB A;  1POD A;  2B04 A;  1BVM A;  1FX9 A;  1FE5 A;  1M8R A;  3QLM A;  1AE7 A;  1VL9 A;  1POA A;  1JIA A;  1PA0 A;  1ZR8 A;  3JTI A;  5G3M A;  4DCF A;  1MF4 A;  1S8G A;  3VC0 A;  3HSW A;  1TH6 A;  1MH8 A;  1PSJ A;  1G4I A;  1LE7 A;  1QLL A;  2O1N A;  2BD1 A;  4YV5 A;  3U8B A;  4AUP A;  2PYC A;  1GMZ A;  1KVX A;  2BAX A;  2ZBH A;  1OZY A;  3Q4Y A;  4QMC A;  2OLI A;  1M8T A;  1T37 A;  1RGB A;  1A3D A;  2BPP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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