4WAMA

H. influenzae beta-carbonic anhydrase variant w39v/g41a/p48s/a49p
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
188
structure length
178
Chain Sequence
TPHYLVIACSDSRVSPEKLPGELFVHRNVANQVIHTDFNCLSVVQYAVDVLKIEHIIICGHTNCGGIHAAMADKDLGLINNWLLHIRDIWFKHGHLLGKLSPEKRADMLTKINVAEQVYNLGRTSIVKSAWERGQKLSLHGWVYGFLVGVMATSRETLEISYRNAIARLSILDEENIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Allosteric Reversion of Haemophilus influenzae beta-Carbonic Anhydrase via a Proline Shift.
pubmed doi rcsb
molecule tags Lyase
source organism Haemophilus influenzae
molecule keywords beta-carbonic anhydrase
total genus 66
structure length 178
sequence length 188
chains with identical sequence B
ec nomenclature ec 4.2.1.1: Carbonic anhydrase.
pdb deposition date 2014-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00484 Pro_CA Carbonic anhydrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1050.10 Alpha Beta 3-Layer(aba) Sandwich Beta-carbonic Anhydrase; Chain A Carbonic anhydrase 4wamA00
3UCNA 3E1WA 4YF6A 3UCOA 3E28A 1YM3A 3E3FA 4WAJA 1G5CA 2W3NA 5CXKA 4WAKA 2A8CA 3EYXA 3TENA 3QY1A 4WAMA 3E1VA 3E2XA 3E3GA 5JJ8A 4O1KA 3UCMA 3VQJA 4O1JA 1YLKA 5BQ1A 4ZNZA 1DDZA 3UCJA 3MF3A 2A5VA 1EKJA 3TEOA 3LASA 2A8DA 3E3IA 1I6PA 1I6OA 3E24A 2W3QA 5SWCA 1T75A 3UCKA 3VRKA 3E2AA 4RXYA 4YF5A 4YF4A 3E31A 2ESFA 3E2WA
chains in the Genus database with same CATH superfamily
3UCNA 3E1WA 4YF6A 3UCOA 3E28A 1YM3A 3E3FA 4WAJA 1G5CA 2W3NA 5CXKA 4WAKA 2A8CA 3EYXA 3TENA 3QY1A 4WAMA 3E1VA 3E2XA 3E3GA 5JJ8A 4O1KA 3UCMA 3VQJA 4O1JA 1YLKA 5BQ1A 4ZNZA 1DDZA 3UCJA 3MF3A 2A5VA 1EKJA 3TEOA 3LASA 2A8DA 3E3IA 1I6PA 1I6OA 3E24A 2W3QA 5SWCA 1T75A 3UCKA 3VRKA 3E2AA 4RXYA 4YF5A 4YF4A 3E31A 2ESFA 3E2WA
chains in the Genus database with same CATH topology
3UCNA 3E1WA 4YF6A 3UCOA 3E28A 1YM3A 3E3FA 4WAJA 1G5CA 2W3NA 5CXKA 4WAKA 2A8CA 3EYXA 3TENA 3QY1A 4WAMA 3E1VA 3E2XA 3E3GA 5JJ8A 4O1KA 3UCMA 3VQJA 4O1JA 1YLKA 5BQ1A 4ZNZA 1DDZA 3UCJA 3MF3A 2A5VA 1EKJA 3TEOA 3LASA 2A8DA 3E3IA 1I6PA 1I6OA 3E24A 2W3QA 5SWCA 1T75A 3UCKA 3VRKA 3E2AA 4RXYA 4YF5A 4YF4A 3E31A 2ESFA 3E2WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UCN A;  3E1W A;  4YF6 A;  3UCO A;  3E28 A;  1YM3 A;  3E3F A;  4WAJ A;  1G5C A;  2W3N A;  5CXK A;  4WAK A;  2A8C A;  3EYX A;  3TEN A;  3QY1 A;  4WAM A;  3E1V A;  3E2X A;  3E3G A;  5JJ8 A;  4O1K A;  3UCM A;  3VQJ A;  4O1J A;  1YLK A;  5BQ1 A;  4ZNZ A;  1DDZ A;  3UCJ A;  3MF3 A;  2A5V A;  1EKJ A;  3TEO A;  3LAS A;  2A8D A;  3E3I A;  1I6P A;  1I6O A;  3E24 A;  2W3Q A;  5SWC A;  1T75 A;  3UCK A;  3VRK A;  3E2A A;  4RXY A;  4YF5 A;  4YF4 A;  3E31 A;  2ESF A;  3E2W A; 
#chains in the Genus database with same CATH topology
 3UCN A;  3E1W A;  4YF6 A;  3UCO A;  3E28 A;  1YM3 A;  3E3F A;  4WAJ A;  1G5C A;  2W3N A;  5CXK A;  4WAK A;  2A8C A;  3EYX A;  3TEN A;  3QY1 A;  4WAM A;  3E1V A;  3E2X A;  3E3G A;  5JJ8 A;  4O1K A;  3UCM A;  3VQJ A;  4O1J A;  1YLK A;  5BQ1 A;  4ZNZ A;  1DDZ A;  3UCJ A;  3MF3 A;  2A5V A;  1EKJ A;  3TEO A;  3LAS A;  2A8D A;  3E3I A;  1I6P A;  1I6O A;  3E24 A;  2W3Q A;  5SWC A;  1T75 A;  3UCK A;  3VRK A;  3E2A A;  4RXY A;  4YF5 A;  4YF4 A;  3E31 A;  2ESF A;  3E2W A; 
#chains in the Genus database with same CATH homology
 3UCN A;  3E1W A;  4YF6 A;  3UCO A;  3E28 A;  1YM3 A;  3E3F A;  4WAJ A;  1G5C A;  2W3N A;  5CXK A;  4WAK A;  2A8C A;  3EYX A;  3TEN A;  3QY1 A;  4WAM A;  3E1V A;  3E2X A;  3E3G A;  5JJ8 A;  4O1K A;  3UCM A;  3VQJ A;  4O1J A;  1YLK A;  5BQ1 A;  4ZNZ A;  1DDZ A;  3UCJ A;  3MF3 A;  2A5V A;  1EKJ A;  3TEO A;  3LAS A;  2A8D A;  3E3I A;  1I6P A;  1I6O A;  3E24 A;  2W3Q A;  5SWC A;  1T75 A;  3UCK A;  3VRK A;  3E2A A;  4RXY A;  4YF5 A;  4YF4 A;  3E31 A;  2ESF A;  3E2W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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