4WBLA

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation f235a
Total Genus 50
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
215
structure length
210
Chain Sequence
FLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEKLELVSYFGKRPPGVLHCTTKACDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mus musculus
molecule keywords 2',3'-cyclic-nucleotide 3'-phosphodiesterase
total genus 50
structure length 210
sequence length 215
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2014-09-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 4wblA00
2YDBA 1WOJA 2YP0A 4WEXA 4WC9A 3ZBZA 2Y3XA 2I3EA 2YPCA 2YQ9A 2ILXA 4WFRA 2YDCA 3ZBRA 4WDDA 4WDFA 2XMIA 4WDBA 4WDHA 2YDDA 4WDAA 2YOZA 4WDGA 4WCAA 5AE0A 4WCCA 2Y1PA 3ZBSA 4WDEA 4WCBA 2YPEA 4WBLA 4WBIA 2YPHA
chains in the Genus database with same CATH superfamily
2YDBA 1WOJA 2YP0A 4WEXA 4WC9A 3ZBZA 2Y3XA 2I3EA 2YPCA 2YQ9A 2ILXA 4WFRA 2YDCA 3ZBRA 4WDDA 4WDFA 2XMIA 4WDBA 4WDHA 2YDDA 4WDAA 2YOZA 4WDGA 4WCAA 5AE0A 4WCCA 2Y1PA 3ZBSA 4WDEA 4WCBA 2YPEA 4WBLA 4WBIA 2YPHA
chains in the Genus database with same CATH topology
2YDBA 1WOJA 2YP0A 4WEXA 4WC9A 3ZBZA 2Y3XA 2I3EA 2YPCA 2YQ9A 2ILXA 4WFRA 2YDCA 3ZBRA 4WDDA 4WDFA 2XMIA 4WDBA 4WDHA 2YDDA 4WDAA 2YOZA 4WDGA 4WCAA 5AE0A 4WCCA 2Y1PA 3ZBSA 4WDEA 4WCBA 2YPEA 4WBLA 4WBIA 2YPHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YDB A;  1WOJ A;  2YP0 A;  4WEX A;  4WC9 A;  3ZBZ A;  2Y3X A;  2I3E A;  2YPC A;  2YQ9 A;  2ILX A;  4WFR A;  2YDC A;  3ZBR A;  4WDD A;  4WDF A;  2XMI A;  4WDB A;  4WDH A;  2YDD A;  4WDA A;  2YOZ A;  4WDG A;  4WCA A;  5AE0 A;  4WCC A;  2Y1P A;  3ZBS A;  4WDE A;  4WCB A;  2YPE A;  4WBL A;  4WBI A;  2YPH A; 
#chains in the Genus database with same CATH topology
 2YDB A;  1WOJ A;  2YP0 A;  4WEX A;  4WC9 A;  3ZBZ A;  2Y3X A;  2I3E A;  2YPC A;  2YQ9 A;  2ILX A;  4WFR A;  2YDC A;  3ZBR A;  4WDD A;  4WDF A;  2XMI A;  4WDB A;  4WDH A;  2YDD A;  4WDA A;  2YOZ A;  4WDG A;  4WCA A;  5AE0 A;  4WCC A;  2Y1P A;  3ZBS A;  4WDE A;  4WCB A;  2YPE A;  4WBL A;  4WBI A;  2YPH A; 
#chains in the Genus database with same CATH homology
 2YDB A;  1WOJ A;  2YP0 A;  4WEX A;  4WC9 A;  3ZBZ A;  2Y3X A;  2I3E A;  2YPC A;  2YQ9 A;  2ILX A;  4WFR A;  2YDC A;  3ZBR A;  4WDD A;  4WDF A;  2XMI A;  4WDB A;  4WDH A;  2YDD A;  4WDA A;  2YOZ A;  4WDG A;  4WCA A;  5AE0 A;  4WCC A;  2Y1P A;  3ZBS A;  4WDE A;  4WCB A;  2YPE A;  4WBL A;  4WBI A;  2YPH A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...