4WC9A

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation f235l
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
215
structure length
206
Chain Sequence
FLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISLELVSYFGKRPPGVLHCTTKLCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
pubmed doi rcsb
molecule keywords 2',3'-cyclic-nucleotide 3'-phosphodiesterase
molecule tags Hydrolase
source organism Mus musculus
total genus 51
structure length 206
sequence length 215
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2014-09-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 4wc9A00
2YOZA 2YQ9A 4WDBA 4WDGA 3ZBSA 4WCCA 4WEXA 4WBLA 4WBIA 2Y1PA 1WOJA 2XMIA 4WDDA 4WCAA 2YP0A 4WFRA 2YPEA 4WC9A 4WDEA 4WDHA 2YDDA 2YDCA 3ZBZA 3ZBRA 4WDFA 4WCBA 4WDAA 5AE0A 2YDBA 2YPCA 2ILXA 2YPHA 2I3EA 2Y3XA
chains in the Genus database with same CATH superfamily
2YOZA 2YQ9A 4WDBA 4WDGA 3ZBSA 4WCCA 4WEXA 4WBLA 4WBIA 2Y1PA 1WOJA 2XMIA 4WDDA 4WCAA 2YP0A 4WFRA 2YPEA 4WC9A 4WDEA 4WDHA 2YDDA 2YDCA 3ZBZA 3ZBRA 4WDFA 4WCBA 4WDAA 5AE0A 2YDBA 2YPCA 2ILXA 2YPHA 2I3EA 2Y3XA
chains in the Genus database with same CATH topology
2YOZA 2YQ9A 4WDBA 4WDGA 3ZBSA 4WCCA 4WEXA 4WBLA 4WBIA 2Y1PA 1WOJA 2XMIA 4WDDA 4WCAA 2YP0A 4WFRA 2YPEA 4WC9A 4WDEA 4WDHA 2YDDA 2YDCA 3ZBZA 3ZBRA 4WDFA 4WCBA 4WDAA 5AE0A 2YDBA 2YPCA 2ILXA 2YPHA 2I3EA 2Y3XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YOZ A;  2YQ9 A;  4WDB A;  4WDG A;  3ZBS A;  4WCC A;  4WEX A;  4WBL A;  4WBI A;  2Y1P A;  1WOJ A;  2XMI A;  4WDD A;  4WCA A;  2YP0 A;  4WFR A;  2YPE A;  4WC9 A;  4WDE A;  4WDH A;  2YDD A;  2YDC A;  3ZBZ A;  3ZBR A;  4WDF A;  4WCB A;  4WDA A;  5AE0 A;  2YDB A;  2YPC A;  2ILX A;  2YPH A;  2I3E A;  2Y3X A; 
#chains in the Genus database with same CATH topology
 2YOZ A;  2YQ9 A;  4WDB A;  4WDG A;  3ZBS A;  4WCC A;  4WEX A;  4WBL A;  4WBI A;  2Y1P A;  1WOJ A;  2XMI A;  4WDD A;  4WCA A;  2YP0 A;  4WFR A;  2YPE A;  4WC9 A;  4WDE A;  4WDH A;  2YDD A;  2YDC A;  3ZBZ A;  3ZBR A;  4WDF A;  4WCB A;  4WDA A;  5AE0 A;  2YDB A;  2YPC A;  2ILX A;  2YPH A;  2I3E A;  2Y3X A; 
#chains in the Genus database with same CATH homology
 2YOZ A;  2YQ9 A;  4WDB A;  4WDG A;  3ZBS A;  4WCC A;  4WEX A;  4WBL A;  4WBI A;  2Y1P A;  1WOJ A;  2XMI A;  4WDD A;  4WCA A;  2YP0 A;  4WFR A;  2YPE A;  4WC9 A;  4WDE A;  4WDH A;  2YDD A;  2YDC A;  3ZBZ A;  3ZBR A;  4WDF A;  4WCB A;  4WDA A;  5AE0 A;  2YDB A;  2YPC A;  2ILX A;  2YPH A;  2I3E A;  2Y3X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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