4WCAA

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation h230q, complexed with citrate
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
218
structure length
206
Chain Sequence
EKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFEKLELVSYFGKRPPGVLQCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGAADVQPVQTGLDLLDILQQVKGGAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mus musculus
molecule keywords 2',3'-cyclic-nucleotide 3'-phosphodiesterase
total genus 54
structure length 206
sequence length 218
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2014-09-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 4wcaA00
2ILXA 3ZBZA 2I3EA 2YQ9A 4WDAA 4WBLA 4WDDA 4WDBA 4WFRA 2YOZA 4WC9A 4WCCA 4WDGA 4WDFA 2YPEA 2XMIA 4WDHA 2YP0A 4WBIA 1WOJA 2YDBA 4WDEA 3ZBRA 2YPHA 4WEXA 2YPCA 4WCBA 2Y1PA 2YDCA 2YDDA 5AE0A 2Y3XA 3ZBSA 4WCAA
chains in the Genus database with same CATH superfamily
2ILXA 3ZBZA 2I3EA 2YQ9A 4WDAA 4WBLA 4WDDA 4WDBA 4WFRA 2YOZA 4WC9A 4WCCA 4WDGA 4WDFA 2YPEA 2XMIA 4WDHA 2YP0A 4WBIA 1WOJA 2YDBA 4WDEA 3ZBRA 2YPHA 4WEXA 2YPCA 4WCBA 2Y1PA 2YDCA 2YDDA 5AE0A 2Y3XA 3ZBSA 4WCAA
chains in the Genus database with same CATH topology
2ILXA 3ZBZA 2I3EA 2YQ9A 4WDAA 4WBLA 4WDDA 4WDBA 4WFRA 2YOZA 4WC9A 4WCCA 4WDGA 4WDFA 2YPEA 2XMIA 4WDHA 2YP0A 4WBIA 1WOJA 2YDBA 4WDEA 3ZBRA 2YPHA 4WEXA 2YPCA 4WCBA 2Y1PA 2YDCA 2YDDA 5AE0A 2Y3XA 3ZBSA 4WCAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ILX A;  3ZBZ A;  2I3E A;  2YQ9 A;  4WDA A;  4WBL A;  4WDD A;  4WDB A;  4WFR A;  2YOZ A;  4WC9 A;  4WCC A;  4WDG A;  4WDF A;  2YPE A;  2XMI A;  4WDH A;  2YP0 A;  4WBI A;  1WOJ A;  2YDB A;  4WDE A;  3ZBR A;  2YPH A;  4WEX A;  2YPC A;  4WCB A;  2Y1P A;  2YDC A;  2YDD A;  5AE0 A;  2Y3X A;  3ZBS A;  4WCA A; 
#chains in the Genus database with same CATH topology
 2ILX A;  3ZBZ A;  2I3E A;  2YQ9 A;  4WDA A;  4WBL A;  4WDD A;  4WDB A;  4WFR A;  2YOZ A;  4WC9 A;  4WCC A;  4WDG A;  4WDF A;  2YPE A;  2XMI A;  4WDH A;  2YP0 A;  4WBI A;  1WOJ A;  2YDB A;  4WDE A;  3ZBR A;  2YPH A;  4WEX A;  2YPC A;  4WCB A;  2Y1P A;  2YDC A;  2YDD A;  5AE0 A;  2Y3X A;  3ZBS A;  4WCA A; 
#chains in the Genus database with same CATH homology
 2ILX A;  3ZBZ A;  2I3E A;  2YQ9 A;  4WDA A;  4WBL A;  4WDD A;  4WDB A;  4WFR A;  2YOZ A;  4WC9 A;  4WCC A;  4WDG A;  4WDF A;  2YPE A;  2XMI A;  4WDH A;  2YP0 A;  4WBI A;  1WOJ A;  2YDB A;  4WDE A;  3ZBR A;  2YPH A;  4WEX A;  2YPC A;  4WCB A;  2Y1P A;  2YDC A;  2YDD A;  5AE0 A;  2Y3X A;  3ZBS A;  4WCA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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