4WCCA

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation p225g
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
217
structure length
205
Chain Sequence
KDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFEKLELVSYFGKRGPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLSEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
pubmed doi rcsb
molecule keywords 2',3'-cyclic-nucleotide 3'-phosphodiesterase
molecule tags Hydrolase
source organism Mus musculus
total genus 48
structure length 205
sequence length 217
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2014-09-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 4wccA00
4WDHA 2YPEA 2YPCA 2YP0A 4WC9A 1WOJA 4WDDA 2ILXA 3ZBZA 2Y3XA 4WDFA 4WDEA 4WCCA 2I3EA 4WDGA 3ZBSA 5AE0A 4WEXA 2XMIA 2YDDA 2Y1PA 4WBIA 4WBLA 4WDAA 4WDBA 4WCBA 2YDCA 4WCAA 2YOZA 4WFRA 2YPHA 2YQ9A 2YDBA 3ZBRA
chains in the Genus database with same CATH superfamily
4WDHA 2YPEA 2YPCA 2YP0A 4WC9A 1WOJA 4WDDA 2ILXA 3ZBZA 2Y3XA 4WDFA 4WDEA 4WCCA 2I3EA 4WDGA 3ZBSA 5AE0A 4WEXA 2XMIA 2YDDA 2Y1PA 4WBIA 4WBLA 4WDAA 4WDBA 4WCBA 2YDCA 4WCAA 2YOZA 4WFRA 2YPHA 2YQ9A 2YDBA 3ZBRA
chains in the Genus database with same CATH topology
4WDHA 2YPEA 2YPCA 2YP0A 4WC9A 1WOJA 4WDDA 2ILXA 3ZBZA 2Y3XA 4WDFA 4WDEA 4WCCA 2I3EA 4WDGA 3ZBSA 5AE0A 4WEXA 2XMIA 2YDDA 2Y1PA 4WBIA 4WBLA 4WDAA 4WDBA 4WCBA 2YDCA 4WCAA 2YOZA 4WFRA 2YPHA 2YQ9A 2YDBA 3ZBRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WDH A;  2YPE A;  2YPC A;  2YP0 A;  4WC9 A;  1WOJ A;  4WDD A;  2ILX A;  3ZBZ A;  2Y3X A;  4WDF A;  4WDE A;  4WCC A;  2I3E A;  4WDG A;  3ZBS A;  5AE0 A;  4WEX A;  2XMI A;  2YDD A;  2Y1P A;  4WBI A;  4WBL A;  4WDA A;  4WDB A;  4WCB A;  2YDC A;  4WCA A;  2YOZ A;  4WFR A;  2YPH A;  2YQ9 A;  2YDB A;  3ZBR A; 
#chains in the Genus database with same CATH topology
 4WDH A;  2YPE A;  2YPC A;  2YP0 A;  4WC9 A;  1WOJ A;  4WDD A;  2ILX A;  3ZBZ A;  2Y3X A;  4WDF A;  4WDE A;  4WCC A;  2I3E A;  4WDG A;  3ZBS A;  5AE0 A;  4WEX A;  2XMI A;  2YDD A;  2Y1P A;  4WBI A;  4WBL A;  4WDA A;  4WDB A;  4WCB A;  2YDC A;  4WCA A;  2YOZ A;  4WFR A;  2YPH A;  2YQ9 A;  2YDB A;  3ZBR A; 
#chains in the Genus database with same CATH homology
 4WDH A;  2YPE A;  2YPC A;  2YP0 A;  4WC9 A;  1WOJ A;  4WDD A;  2ILX A;  3ZBZ A;  2Y3X A;  4WDF A;  4WDE A;  4WCC A;  2I3E A;  4WDG A;  3ZBS A;  5AE0 A;  4WEX A;  2XMI A;  2YDD A;  2Y1P A;  4WBI A;  4WBL A;  4WDA A;  4WDB A;  4WCB A;  2YDC A;  4WCA A;  2YOZ A;  4WFR A;  2YPH A;  2YQ9 A;  2YDB A;  3ZBR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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