4WDAA

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation p296g, complexed with 2'-amp
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
218
structure length
211
Chain Sequence
EKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGKEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
pubmed doi rcsb
molecule keywords 2',3'-cyclic-nucleotide 3'-phosphodiesterase
molecule tags Hydrolase
source organism Mus musculus
total genus 53
structure length 211
sequence length 218
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2014-09-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 4wdaA00
4WBIA 4WFRA 4WCAA 4WCCA 2YPEA 3ZBRA 2YDBA 2Y3XA 1WOJA 4WDGA 2YDDA 3ZBZA 4WCBA 4WDBA 2YP0A 2YDCA 4WC9A 2XMIA 2YOZA 4WDEA 4WEXA 4WDDA 2Y1PA 3ZBSA 2ILXA 4WBLA 2YPHA 2YQ9A 4WDHA 2YPCA 5AE0A 2I3EA 4WDFA 4WDAA
chains in the Genus database with same CATH superfamily
4WBIA 4WFRA 4WCAA 4WCCA 2YPEA 3ZBRA 2YDBA 2Y3XA 1WOJA 4WDGA 2YDDA 3ZBZA 4WCBA 4WDBA 2YP0A 2YDCA 4WC9A 2XMIA 2YOZA 4WDEA 4WEXA 4WDDA 2Y1PA 3ZBSA 2ILXA 4WBLA 2YPHA 2YQ9A 4WDHA 2YPCA 5AE0A 2I3EA 4WDFA 4WDAA
chains in the Genus database with same CATH topology
4WBIA 4WFRA 4WCAA 4WCCA 2YPEA 3ZBRA 2YDBA 2Y3XA 1WOJA 4WDGA 2YDDA 3ZBZA 4WCBA 4WDBA 2YP0A 2YDCA 4WC9A 2XMIA 2YOZA 4WDEA 4WEXA 4WDDA 2Y1PA 3ZBSA 2ILXA 4WBLA 2YPHA 2YQ9A 4WDHA 2YPCA 5AE0A 2I3EA 4WDFA 4WDAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WBI A;  4WFR A;  4WCA A;  4WCC A;  2YPE A;  3ZBR A;  2YDB A;  2Y3X A;  1WOJ A;  4WDG A;  2YDD A;  3ZBZ A;  4WCB A;  4WDB A;  2YP0 A;  2YDC A;  4WC9 A;  2XMI A;  2YOZ A;  4WDE A;  4WEX A;  4WDD A;  2Y1P A;  3ZBS A;  2ILX A;  4WBL A;  2YPH A;  2YQ9 A;  4WDH A;  2YPC A;  5AE0 A;  2I3E A;  4WDF A;  4WDA A; 
#chains in the Genus database with same CATH topology
 4WBI A;  4WFR A;  4WCA A;  4WCC A;  2YPE A;  3ZBR A;  2YDB A;  2Y3X A;  1WOJ A;  4WDG A;  2YDD A;  3ZBZ A;  4WCB A;  4WDB A;  2YP0 A;  2YDC A;  4WC9 A;  2XMI A;  2YOZ A;  4WDE A;  4WEX A;  4WDD A;  2Y1P A;  3ZBS A;  2ILX A;  4WBL A;  2YPH A;  2YQ9 A;  4WDH A;  2YPC A;  5AE0 A;  2I3E A;  4WDF A;  4WDA A; 
#chains in the Genus database with same CATH homology
 4WBI A;  4WFR A;  4WCA A;  4WCC A;  2YPE A;  3ZBR A;  2YDB A;  2Y3X A;  1WOJ A;  4WDG A;  2YDD A;  3ZBZ A;  4WCB A;  4WDB A;  2YP0 A;  2YDC A;  4WC9 A;  2XMI A;  2YOZ A;  4WDE A;  4WEX A;  4WDD A;  2Y1P A;  3ZBS A;  2ILX A;  4WBL A;  2YPH A;  2YQ9 A;  4WDH A;  2YPC A;  5AE0 A;  2I3E A;  4WDF A;  4WDA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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