4WDBA

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation r307q, complexed with 2'-amp
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
218
structure length
212
Chain Sequence
EKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFIEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSQAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mus musculus
molecule keywords 2',3'-cyclic-nucleotide 3'-phosphodiesterase
total genus 53
structure length 212
sequence length 218
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2014-09-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 4wdbA00
2YQ9A 4WEXA 4WDBA 3ZBRA 5AE0A 4WFRA 2YDBA 3ZBZA 2Y3XA 4WDAA 2YDDA 4WDHA 2ILXA 2YDCA 2Y1PA 4WBLA 3ZBSA 4WDFA 2YPHA 1WOJA 2YP0A 4WCCA 4WBIA 4WCAA 2I3EA 4WC9A 4WDEA 4WDDA 2YOZA 2YPCA 2YPEA 2XMIA 4WDGA 4WCBA
chains in the Genus database with same CATH superfamily
2YQ9A 4WEXA 4WDBA 3ZBRA 5AE0A 4WFRA 2YDBA 3ZBZA 2Y3XA 4WDAA 2YDDA 4WDHA 2ILXA 2YDCA 2Y1PA 4WBLA 3ZBSA 4WDFA 2YPHA 1WOJA 2YP0A 4WCCA 4WBIA 4WCAA 2I3EA 4WC9A 4WDEA 4WDDA 2YOZA 2YPCA 2YPEA 2XMIA 4WDGA 4WCBA
chains in the Genus database with same CATH topology
2YQ9A 4WEXA 4WDBA 3ZBRA 5AE0A 4WFRA 2YDBA 3ZBZA 2Y3XA 4WDAA 2YDDA 4WDHA 2ILXA 2YDCA 2Y1PA 4WBLA 3ZBSA 4WDFA 2YPHA 1WOJA 2YP0A 4WCCA 4WBIA 4WCAA 2I3EA 4WC9A 4WDEA 4WDDA 2YOZA 2YPCA 2YPEA 2XMIA 4WDGA 4WCBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YQ9 A;  4WEX A;  4WDB A;  3ZBR A;  5AE0 A;  4WFR A;  2YDB A;  3ZBZ A;  2Y3X A;  4WDA A;  2YDD A;  4WDH A;  2ILX A;  2YDC A;  2Y1P A;  4WBL A;  3ZBS A;  4WDF A;  2YPH A;  1WOJ A;  2YP0 A;  4WCC A;  4WBI A;  4WCA A;  2I3E A;  4WC9 A;  4WDE A;  4WDD A;  2YOZ A;  2YPC A;  2YPE A;  2XMI A;  4WDG A;  4WCB A; 
#chains in the Genus database with same CATH topology
 2YQ9 A;  4WEX A;  4WDB A;  3ZBR A;  5AE0 A;  4WFR A;  2YDB A;  3ZBZ A;  2Y3X A;  4WDA A;  2YDD A;  4WDH A;  2ILX A;  2YDC A;  2Y1P A;  4WBL A;  3ZBS A;  4WDF A;  2YPH A;  1WOJ A;  2YP0 A;  4WCC A;  4WBI A;  4WCA A;  2I3E A;  4WC9 A;  4WDE A;  4WDD A;  2YOZ A;  2YPC A;  2YPE A;  2XMI A;  4WDG A;  4WCB A; 
#chains in the Genus database with same CATH homology
 2YQ9 A;  4WEX A;  4WDB A;  3ZBR A;  5AE0 A;  4WFR A;  2YDB A;  3ZBZ A;  2Y3X A;  4WDA A;  2YDD A;  4WDH A;  2ILX A;  2YDC A;  2Y1P A;  4WBL A;  3ZBS A;  4WDF A;  2YPH A;  1WOJ A;  2YP0 A;  4WCC A;  4WBI A;  4WCA A;  2I3E A;  4WC9 A;  4WDE A;  4WDD A;  2YOZ A;  2YPC A;  2YPE A;  2XMI A;  4WDG A;  4WCB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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