4WDDA

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation t232a, complexed with citrate
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
218
structure length
207
Chain Sequence
EKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGEKLELVSYFGKRPPGVLHCATKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
pubmed doi rcsb
molecule keywords 2',3'-cyclic-nucleotide 3'-phosphodiesterase
molecule tags Hydrolase
source organism Mus musculus
total genus 49
structure length 207
sequence length 218
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2014-09-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 4wddA00
3ZBSA 4WCAA 2Y1PA 2YPHA 4WDHA 2YDBA 2YOZA 4WDGA 2YQ9A 4WEXA 2YPEA 4WDAA 4WCBA 2YDDA 2YP0A 2Y3XA 2ILXA 4WDDA 2YDCA 4WCCA 4WBLA 3ZBRA 4WBIA 3ZBZA 4WC9A 4WFRA 5AE0A 4WDBA 2YPCA 1WOJA 4WDEA 2XMIA 4WDFA 2I3EA
chains in the Genus database with same CATH superfamily
3ZBSA 4WCAA 2Y1PA 2YPHA 4WDHA 2YDBA 2YOZA 4WDGA 2YQ9A 4WEXA 2YPEA 4WDAA 4WCBA 2YDDA 2YP0A 2Y3XA 2ILXA 4WDDA 2YDCA 4WCCA 4WBLA 3ZBRA 4WBIA 3ZBZA 4WC9A 4WFRA 5AE0A 4WDBA 2YPCA 1WOJA 4WDEA 2XMIA 4WDFA 2I3EA
chains in the Genus database with same CATH topology
3ZBSA 4WCAA 2Y1PA 2YPHA 4WDHA 2YDBA 2YOZA 4WDGA 2YQ9A 4WEXA 2YPEA 4WDAA 4WCBA 2YDDA 2YP0A 2Y3XA 2ILXA 4WDDA 2YDCA 4WCCA 4WBLA 3ZBRA 4WBIA 3ZBZA 4WC9A 4WFRA 5AE0A 4WDBA 2YPCA 1WOJA 4WDEA 2XMIA 4WDFA 2I3EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZBS A;  4WCA A;  2Y1P A;  2YPH A;  4WDH A;  2YDB A;  2YOZ A;  4WDG A;  2YQ9 A;  4WEX A;  2YPE A;  4WDA A;  4WCB A;  2YDD A;  2YP0 A;  2Y3X A;  2ILX A;  4WDD A;  2YDC A;  4WCC A;  4WBL A;  3ZBR A;  4WBI A;  3ZBZ A;  4WC9 A;  4WFR A;  5AE0 A;  4WDB A;  2YPC A;  1WOJ A;  4WDE A;  2XMI A;  4WDF A;  2I3E A; 
#chains in the Genus database with same CATH topology
 3ZBS A;  4WCA A;  2Y1P A;  2YPH A;  4WDH A;  2YDB A;  2YOZ A;  4WDG A;  2YQ9 A;  4WEX A;  2YPE A;  4WDA A;  4WCB A;  2YDD A;  2YP0 A;  2Y3X A;  2ILX A;  4WDD A;  2YDC A;  4WCC A;  4WBL A;  3ZBR A;  4WBI A;  3ZBZ A;  4WC9 A;  4WFR A;  5AE0 A;  4WDB A;  2YPC A;  1WOJ A;  4WDE A;  2XMI A;  4WDF A;  2I3E A; 
#chains in the Genus database with same CATH homology
 3ZBS A;  4WCA A;  2Y1P A;  2YPH A;  4WDH A;  2YDB A;  2YOZ A;  4WDG A;  2YQ9 A;  4WEX A;  2YPE A;  4WDA A;  4WCB A;  2YDD A;  2YP0 A;  2Y3X A;  2ILX A;  4WDD A;  2YDC A;  4WCC A;  4WBL A;  3ZBR A;  4WBI A;  3ZBZ A;  4WC9 A;  4WFR A;  5AE0 A;  4WDB A;  2YPC A;  1WOJ A;  4WDE A;  2XMI A;  4WDF A;  2I3E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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