4WDDA

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation t232a, complexed with citrate
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
218
structure length
207
Chain Sequence
EKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGEKLELVSYFGKRPPGVLHCATKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mus musculus
molecule keywords 2',3'-cyclic-nucleotide 3'-phosphodiesterase
total genus 49
structure length 207
sequence length 218
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2014-09-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 4wddA00
2YQ9A 4WDAA 1WOJA 2Y1PA 4WDGA 3ZBRA 4WC9A 2YDCA 4WDDA 2YPCA 2ILXA 2YDDA 4WEXA 2YOZA 4WDHA 2YP0A 4WDFA 3ZBZA 4WCAA 3ZBSA 4WBLA 4WDEA 5AE0A 4WFRA 2YPHA 2Y3XA 2YDBA 2I3EA 2XMIA 4WCCA 4WDBA 4WBIA 4WCBA 2YPEA
chains in the Genus database with same CATH superfamily
2YQ9A 4WDAA 1WOJA 2Y1PA 4WDGA 3ZBRA 4WC9A 2YDCA 4WDDA 2YPCA 2ILXA 2YDDA 4WEXA 2YOZA 4WDHA 2YP0A 4WDFA 3ZBZA 4WCAA 3ZBSA 4WBLA 4WDEA 5AE0A 4WFRA 2YPHA 2Y3XA 2YDBA 2I3EA 2XMIA 4WCCA 4WDBA 4WBIA 4WCBA 2YPEA
chains in the Genus database with same CATH topology
2YQ9A 4WDAA 1WOJA 2Y1PA 4WDGA 3ZBRA 4WC9A 2YDCA 4WDDA 2YPCA 2ILXA 2YDDA 4WEXA 2YOZA 4WDHA 2YP0A 4WDFA 3ZBZA 4WCAA 3ZBSA 4WBLA 4WDEA 5AE0A 4WFRA 2YPHA 2Y3XA 2YDBA 2I3EA 2XMIA 4WCCA 4WDBA 4WBIA 4WCBA 2YPEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YQ9 A;  4WDA A;  1WOJ A;  2Y1P A;  4WDG A;  3ZBR A;  4WC9 A;  2YDC A;  4WDD A;  2YPC A;  2ILX A;  2YDD A;  4WEX A;  2YOZ A;  4WDH A;  2YP0 A;  4WDF A;  3ZBZ A;  4WCA A;  3ZBS A;  4WBL A;  4WDE A;  5AE0 A;  4WFR A;  2YPH A;  2Y3X A;  2YDB A;  2I3E A;  2XMI A;  4WCC A;  4WDB A;  4WBI A;  4WCB A;  2YPE A; 
#chains in the Genus database with same CATH topology
 2YQ9 A;  4WDA A;  1WOJ A;  2Y1P A;  4WDG A;  3ZBR A;  4WC9 A;  2YDC A;  4WDD A;  2YPC A;  2ILX A;  2YDD A;  4WEX A;  2YOZ A;  4WDH A;  2YP0 A;  4WDF A;  3ZBZ A;  4WCA A;  3ZBS A;  4WBL A;  4WDE A;  5AE0 A;  4WFR A;  2YPH A;  2Y3X A;  2YDB A;  2I3E A;  2XMI A;  4WCC A;  4WDB A;  4WBI A;  4WCB A;  2YPE A; 
#chains in the Genus database with same CATH homology
 2YQ9 A;  4WDA A;  1WOJ A;  2Y1P A;  4WDG A;  3ZBR A;  4WC9 A;  2YDC A;  4WDD A;  2YPC A;  2ILX A;  2YDD A;  4WEX A;  2YOZ A;  4WDH A;  2YP0 A;  4WDF A;  3ZBZ A;  4WCA A;  3ZBS A;  4WBL A;  4WDE A;  5AE0 A;  4WFR A;  2YPH A;  2Y3X A;  2YDB A;  2I3E A;  2XMI A;  4WCC A;  4WDB A;  4WBI A;  4WCB A;  2YPE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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