4WDEA

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation t311a
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
218
structure length
215
Chain Sequence
EKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGKEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVALGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mus musculus
molecule keywords 2',3'-cyclic-nucleotide 3'-phosphodiesterase
total genus 52
structure length 215
sequence length 218
chains with identical sequence B
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2014-09-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 4wdeA00
2Y3XA 4WDBA 2XMIA 2I3EA 2YDBA 5AE0A 4WEXA 3ZBZA 2YOZA 4WCAA 3ZBRA 2YPCA 4WCCA 2YPEA 2YPHA 4WDDA 4WDFA 2YQ9A 4WC9A 1WOJA 4WDEA 2YP0A 4WCBA 4WBIA 2YDDA 2YDCA 4WFRA 3ZBSA 4WDAA 2ILXA 2Y1PA 4WDGA 4WBLA 4WDHA
chains in the Genus database with same CATH superfamily
2Y3XA 4WDBA 2XMIA 2I3EA 2YDBA 5AE0A 4WEXA 3ZBZA 2YOZA 4WCAA 3ZBRA 2YPCA 4WCCA 2YPEA 2YPHA 4WDDA 4WDFA 2YQ9A 4WC9A 1WOJA 4WDEA 2YP0A 4WCBA 4WBIA 2YDDA 2YDCA 4WFRA 3ZBSA 4WDAA 2ILXA 2Y1PA 4WDGA 4WBLA 4WDHA
chains in the Genus database with same CATH topology
2Y3XA 4WDBA 2XMIA 2I3EA 2YDBA 5AE0A 4WEXA 3ZBZA 2YOZA 4WCAA 3ZBRA 2YPCA 4WCCA 2YPEA 2YPHA 4WDDA 4WDFA 2YQ9A 4WC9A 1WOJA 4WDEA 2YP0A 4WCBA 4WBIA 2YDDA 2YDCA 4WFRA 3ZBSA 4WDAA 2ILXA 2Y1PA 4WDGA 4WBLA 4WDHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y3X A;  4WDB A;  2XMI A;  2I3E A;  2YDB A;  5AE0 A;  4WEX A;  3ZBZ A;  2YOZ A;  4WCA A;  3ZBR A;  2YPC A;  4WCC A;  2YPE A;  2YPH A;  4WDD A;  4WDF A;  2YQ9 A;  4WC9 A;  1WOJ A;  4WDE A;  2YP0 A;  4WCB A;  4WBI A;  2YDD A;  2YDC A;  4WFR A;  3ZBS A;  4WDA A;  2ILX A;  2Y1P A;  4WDG A;  4WBL A;  4WDH A; 
#chains in the Genus database with same CATH topology
 2Y3X A;  4WDB A;  2XMI A;  2I3E A;  2YDB A;  5AE0 A;  4WEX A;  3ZBZ A;  2YOZ A;  4WCA A;  3ZBR A;  2YPC A;  4WCC A;  2YPE A;  2YPH A;  4WDD A;  4WDF A;  2YQ9 A;  4WC9 A;  1WOJ A;  4WDE A;  2YP0 A;  4WCB A;  4WBI A;  2YDD A;  2YDC A;  4WFR A;  3ZBS A;  4WDA A;  2ILX A;  2Y1P A;  4WDG A;  4WBL A;  4WDH A; 
#chains in the Genus database with same CATH homology
 2Y3X A;  4WDB A;  2XMI A;  2I3E A;  2YDB A;  5AE0 A;  4WEX A;  3ZBZ A;  2YOZ A;  4WCA A;  3ZBR A;  2YPC A;  4WCC A;  2YPE A;  2YPH A;  4WDD A;  4WDF A;  2YQ9 A;  4WC9 A;  1WOJ A;  4WDE A;  2YP0 A;  4WCB A;  4WBI A;  2YDD A;  2YDC A;  4WFR A;  3ZBS A;  4WDA A;  2ILX A;  2Y1P A;  4WDG A;  4WBL A;  4WDH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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