4WDHA

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation y168a
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
217
structure length
213
Chain Sequence
KDFLPLAFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEPKEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mus musculus
molecule keywords 2',3'-cyclic-nucleotide 3'-phosphodiesterase
total genus 49
structure length 213
sequence length 217
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2014-09-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 4wdhA00
4WDGA 4WCCA 4WBIA 3ZBRA 2YPEA 2Y3XA 2YDDA 4WDBA 2ILXA 4WCAA 5AE0A 2YPCA 2YOZA 4WDFA 2YDBA 3ZBSA 4WDHA 1WOJA 3ZBZA 2YQ9A 4WDEA 4WDAA 2YPHA 4WC9A 2YP0A 4WBLA 4WEXA 2YDCA 2XMIA 4WFRA 4WCBA 4WDDA 2Y1PA 2I3EA
chains in the Genus database with same CATH superfamily
4WDGA 4WCCA 4WBIA 3ZBRA 2YPEA 2Y3XA 2YDDA 4WDBA 2ILXA 4WCAA 5AE0A 2YPCA 2YOZA 4WDFA 2YDBA 3ZBSA 4WDHA 1WOJA 3ZBZA 2YQ9A 4WDEA 4WDAA 2YPHA 4WC9A 2YP0A 4WBLA 4WEXA 2YDCA 2XMIA 4WFRA 4WCBA 4WDDA 2Y1PA 2I3EA
chains in the Genus database with same CATH topology
4WDGA 4WCCA 4WBIA 3ZBRA 2YPEA 2Y3XA 2YDDA 4WDBA 2ILXA 4WCAA 5AE0A 2YPCA 2YOZA 4WDFA 2YDBA 3ZBSA 4WDHA 1WOJA 3ZBZA 2YQ9A 4WDEA 4WDAA 2YPHA 4WC9A 2YP0A 4WBLA 4WEXA 2YDCA 2XMIA 4WFRA 4WCBA 4WDDA 2Y1PA 2I3EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WDG A;  4WCC A;  4WBI A;  3ZBR A;  2YPE A;  2Y3X A;  2YDD A;  4WDB A;  2ILX A;  4WCA A;  5AE0 A;  2YPC A;  2YOZ A;  4WDF A;  2YDB A;  3ZBS A;  4WDH A;  1WOJ A;  3ZBZ A;  2YQ9 A;  4WDE A;  4WDA A;  2YPH A;  4WC9 A;  2YP0 A;  4WBL A;  4WEX A;  2YDC A;  2XMI A;  4WFR A;  4WCB A;  4WDD A;  2Y1P A;  2I3E A; 
#chains in the Genus database with same CATH topology
 4WDG A;  4WCC A;  4WBI A;  3ZBR A;  2YPE A;  2Y3X A;  2YDD A;  4WDB A;  2ILX A;  4WCA A;  5AE0 A;  2YPC A;  2YOZ A;  4WDF A;  2YDB A;  3ZBS A;  4WDH A;  1WOJ A;  3ZBZ A;  2YQ9 A;  4WDE A;  4WDA A;  2YPH A;  4WC9 A;  2YP0 A;  4WBL A;  4WEX A;  2YDC A;  2XMI A;  4WFR A;  4WCB A;  4WDD A;  2Y1P A;  2I3E A; 
#chains in the Genus database with same CATH homology
 4WDG A;  4WCC A;  4WBI A;  3ZBR A;  2YPE A;  2Y3X A;  2YDD A;  4WDB A;  2ILX A;  4WCA A;  5AE0 A;  2YPC A;  2YOZ A;  4WDF A;  2YDB A;  3ZBS A;  4WDH A;  1WOJ A;  3ZBZ A;  2YQ9 A;  4WDE A;  4WDA A;  2YPH A;  4WC9 A;  2YP0 A;  4WBL A;  4WEX A;  2YDC A;  2XMI A;  4WFR A;  4WCB A;  4WDD A;  2Y1P A;  2I3E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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