4YQHA

2-[2-(4-phenyl-1h-imidazol-2-yl)ethyl]quinoxaline (sunovion compound 14) co-crystallized with pde10a
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
321
structure length
321
Chain Sequence
SICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
publication title Evolution and synthesis of novel orally bioavailable inhibitors of PDE10A.
pubmed doi rcsb
molecule keywords cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase
total genus 128
structure length 321
sequence length 321
chains with identical sequence B
ec nomenclature ec 3.1.4.17: 3',5'-cyclic-nucleotide phosphodiesterase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00233 PDEase_I 3'5'-cyclic nucleotide phosphodiesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1300.10 Mainly Alpha Orthogonal Bundle Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 4yqhA00
2H44A 4I15A 3V93A 4MS0A 4MSEA 4AJMA 3SL8A 4WZIA 3QPNA 2O8HA 4Y87A 3TGEA 2QYNA 4TPMA 1XMYB 3HQZA 4OEXA 2OUPA 4LM0A 1UDUA 1RORA 3TGGA 4D09A 3WYMA 1T9SA 1Y2BA 4AELA 1Y2JA 3SNLA 4Y2BA 1XLZA 3SHZA 2Y0JA 4AJFA 5K1IA 2OVVA 1OYNA 3JSIA 3ITMA 3K3EA 3W5EA 5C1WA 3BJCA 2QYMA 3TVXA 3SL4A 3K4SA 1XM6A 3G4KA 3IADA 4GH6A 3V94A 3ITUA 1XMUB 4MRWA 2H40A 4NPVA 3JWQA 1XOQA 4XY2A 4MD6A 2OUVA 3N3ZA 2FM0A 2QYKA 4YQHA 3ECNA 4AJDA 1TBBA 4WN1A 5I2RA 4OGBA 5DH5A 2OURA 1Y2KA 1TAZA 4HTXA 1TBFA 3HDZA 4QGEA 5EDIB 4MSCA 3WD9A 3SHYA 1Y2DA 3HQYA 5EDGB 1XORA 2YY2A 4PHWA 2WEYA 4P0NA 3I8VA 1XOSA 2HD1A 1UHOA 1XM4A 3D3PA 3GWTA 3HR1A 3LXGA 5EDHA 3ECMA 4HEUA 4DFFA 1XONA 1Z1LA 5DH4A 2PW3A 1F0JA 5C28A 1XMYA 5C2HA 1XOTA 2QYLA 4LLPA 2H42A 3SNIA 2OUQA 4P1RA 1Y2CA 1SO2A 4WCUA 4DDLA 4NW7A 4G2WA 1TB5A 1RO9A 3WS8A 1UDTA 3QPOA 1Q9MA 4LM2A 4MUWA 3O0JA 1PTWA 4Y8CA 3G45A 4MYQA 1Y2EA 2OVYA 3JWRA 4OEWA 3HMVA 3WI2A 5B4LA 2OUNA 2FM5A 3QI3A 4LM1A 3LY2A 5EDEA 4HF4A 1XOMA 3IBJA 4LM3A 3HQWA 5C29A 3DYNA 1MKDA 2OUYA 3WYLA 3G4GA 3FRGA 3UI7A 1Y2HA 4LKQA 4NPWA 3SN7A 3SL3A 4BBXA 1XMUA 1XN0A 4HTZA 4IA0A 4E90A 4ZO5A 4FCDA 3G4LA 4W1OA 3SIEA 4LLKA 4LM4A 1T9RA 1XLXA 3WYKA 3DYLA 3G3NA 4X0FA 4G2JA 1RKPA 4LLJA 4C1IA 5B4KA 3KKTA 3QI4A 3DYSA 4I9ZA 3HC8A 5EDIA 5AXQA 3UUOA 5B25A 4PM0A 3DYQA 5EDGA 4G2LA 4JIBA 5K32A 4AJGA 2OUUA 4TPPA 4MRZA 3G4IA 1TB7A 5C2EA 4MSHA 1ZKLA 2OUSA 4G2YA 1ZKNA 4MSNA 4Y86A 5C2AA 3DY8A 3SL5A 4D08A 4MSAA 4KP6A 3O57A 2CHMA 3O56A 3QPPA 4FCBA 3K3HA 4PHLA 5EDEB 1XP0A 4MVHA 1XOZA 4YS7A 2R8QA 3JSWA 3WS9A 5K9RA 3SL6A 3G58A 5AXPA 4LLXA 3IAKA 1RO6A 3V9BA 1XM4B 3B2RA 1SOJA
chains in the Genus database with same CATH superfamily
2H44A 4I15A 3V93A 4MS0A 4MSEA 4AJMA 3SL8A 4WZIA 3QPNA 2O8HA 4Y87A 3TGEA 2QYNA 4TPMA 1XMYB 3HQZA 4OEXA 2OUPA 4LM0A 1UDUA 1RORA 3TGGA 4D09A 3WYMA 1T9SA 1Y2BA 4AELA 1Y2JA 3SNLA 4Y2BA 1XLZA 3SHZA 2Y0JA 4AJFA 5K1IA 2OVVA 1OYNA 3JSIA 3ITMA 3K3EA 3W5EA 5C1WA 3BJCA 2QYMA 3TVXA 3SL4A 3K4SA 1XM6A 3G4KA 3IADA 4GH6A 3V94A 3ITUA 1XMUB 4MRWA 2H40A 4NPVA 3JWQA 1XOQA 4XY2A 4MD6A 2OUVA 3N3ZA 2FM0A 2QYKA 4YQHA 3ECNA 4AJDA 1TBBA 4WN1A 5I2RA 4OGBA 5DH5A 2OURA 1Y2KA 1TAZA 4HTXA 1TBFA 3HDZA 4QGEA 5EDIB 4MSCA 3WD9A 3SHYA 1Y2DA 3HQYA 5EDGB 1XORA 2YY2A 4PHWA 2WEYA 4P0NA 3I8VA 1XOSA 2HD1A 1UHOA 1XM4A 3D3PA 3GWTA 3HR1A 3LXGA 5EDHA 3ECMA 4HEUA 4DFFA 1XONA 1Z1LA 5DH4A 2PW3A 1F0JA 5C28A 1XMYA 5C2HA 1XOTA 2QYLA 4LLPA 2H42A 3SNIA 2OUQA 4P1RA 1Y2CA 1SO2A 4WCUA 4DDLA 4NW7A 4G2WA 1TB5A 1RO9A 3WS8A 1UDTA 3QPOA 1Q9MA 4LM2A 4MUWA 3O0JA 1PTWA 4Y8CA 3G45A 4MYQA 1Y2EA 2OVYA 3JWRA 4OEWA 3HMVA 3WI2A 5B4LA 2OUNA 2FM5A 3QI3A 4LM1A 3LY2A 5EDEA 4HF4A 1XOMA 3IBJA 4LM3A 3HQWA 5C29A 3DYNA 1MKDA 2OUYA 3WYLA 3G4GA 3FRGA 3UI7A 1Y2HA 4LKQA 4NPWA 3SN7A 3SL3A 4BBXA 1XMUA 1XN0A 4HTZA 4IA0A 4E90A 4ZO5A 4FCDA 3G4LA 4W1OA 3SIEA 4LLKA 4LM4A 1T9RA 1XLXA 3WYKA 3DYLA 3G3NA 4X0FA 4G2JA 1RKPA 4LLJA 4C1IA 5B4KA 3KKTA 3QI4A 3DYSA 4I9ZA 3HC8A 5EDIA 5AXQA 3UUOA 5B25A 4PM0A 3DYQA 5EDGA 4G2LA 4JIBA 5K32A 4AJGA 2OUUA 4TPPA 4MRZA 3G4IA 1TB7A 5C2EA 4MSHA 1ZKLA 2OUSA 4G2YA 1ZKNA 4MSNA 4Y86A 5C2AA 3DY8A 3SL5A 4D08A 4MSAA 4KP6A 3O57A 2CHMA 3O56A 3QPPA 4FCBA 3K3HA 4PHLA 5EDEB 1XP0A 4MVHA 1XOZA 4YS7A 2R8QA 3JSWA 3WS9A 5K9RA 3SL6A 3G58A 5AXPA 4LLXA 3IAKA 1RO6A 3V9BA 1XM4B 3B2RA 1SOJA
chains in the Genus database with same CATH topology
2H44A 4I15A 3V93A 4MS0A 4MSEA 4AJMA 3SL8A 4WZIA 3QPNA 2O8HA 4Y87A 3TGEA 2QYNA 4TPMA 1XMYB 3HQZA 4OEXA 2OUPA 4LM0A 1UDUA 1RORA 3TGGA 4D09A 3WYMA 1T9SA 1Y2BA 4AELA 1Y2JA 3SNLA 4Y2BA 1XLZA 3SHZA 2Y0JA 4AJFA 5K1IA 2OVVA 1OYNA 3JSIA 3ITMA 3K3EA 3W5EA 5C1WA 3BJCA 2QYMA 3TVXA 3SL4A 3K4SA 1XM6A 3G4KA 3IADA 4GH6A 3V94A 3ITUA 1XMUB 4MRWA 2H40A 4NPVA 3JWQA 1XOQA 4XY2A 4MD6A 2OUVA 3N3ZA 2FM0A 2QYKA 4YQHA 3ECNA 4AJDA 1TBBA 4WN1A 5I2RA 4OGBA 5DH5A 2OURA 1Y2KA 1TAZA 4HTXA 1TBFA 3HDZA 4QGEA 5EDIB 4MSCA 3WD9A 3SHYA 1Y2DA 3HQYA 5EDGB 1XORA 2YY2A 4PHWA 2WEYA 4P0NA 3I8VA 1XOSA 2HD1A 1UHOA 1XM4A 3D3PA 3GWTA 3HR1A 3LXGA 5EDHA 3ECMA 4HEUA 4DFFA 1XONA 1Z1LA 5DH4A 2PW3A 1F0JA 5C28A 1XMYA 5C2HA 1XOTA 2QYLA 4LLPA 2H42A 3SNIA 2OUQA 4P1RA 1Y2CA 1SO2A 4WCUA 4DDLA 4NW7A 4G2WA 1TB5A 1RO9A 3WS8A 1UDTA 3QPOA 1Q9MA 4LM2A 4MUWA 3O0JA 1PTWA 4Y8CA 3G45A 4MYQA 1Y2EA 2OVYA 3JWRA 4OEWA 3HMVA 3WI2A 5B4LA 2OUNA 2FM5A 3QI3A 4LM1A 3LY2A 5EDEA 4HF4A 1XOMA 3IBJA 4LM3A 3HQWA 5C29A 3DYNA 1MKDA 2OUYA 3WYLA 3G4GA 3FRGA 3UI7A 1Y2HA 4LKQA 4NPWA 3SN7A 3SL3A 4BBXA 1XMUA 1XN0A 4HTZA 4IA0A 4E90A 4ZO5A 4FCDA 3G4LA 4W1OA 3SIEA 4LLKA 4LM4A 1T9RA 1XLXA 3WYKA 3DYLA 3G3NA 4X0FA 4G2JA 1RKPA 4LLJA 4C1IA 5B4KA 3KKTA 3QI4A 3DYSA 4I9ZA 3HC8A 5EDIA 5AXQA 3UUOA 5B25A 4PM0A 3DYQA 5EDGA 4G2LA 4JIBA 5K32A 4AJGA 2OUUA 4TPPA 4MRZA 3G4IA 1TB7A 5C2EA 4MSHA 1ZKLA 2OUSA 4G2YA 1ZKNA 4MSNA 4Y86A 5C2AA 3DY8A 3SL5A 4D08A 4MSAA 4KP6A 3O57A 2CHMA 3O56A 3QPPA 4FCBA 3K3HA 4PHLA 5EDEB 1XP0A 4MVHA 1XOZA 4YS7A 2R8QA 3JSWA 3WS9A 5K9RA 3SL6A 3G58A 5AXPA 4LLXA 3IAKA 1RO6A 3V9BA 1XM4B 3B2RA 1SOJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H44 A;  4I15 A;  3V93 A;  4MS0 A;  4MSE A;  4AJM A;  3SL8 A;  4WZI A;  3QPN A;  2O8H A;  4Y87 A;  3TGE A;  2QYN A;  4TPM A;  1XMY B;  3HQZ A;  4OEX A;  2OUP A;  4LM0 A;  1UDU A;  1ROR A;  3TGG A;  4D09 A;  3WYM A;  1T9S A;  1Y2B A;  4AEL A;  1Y2J A;  3SNL A;  4Y2B A;  1XLZ A;  3SHZ A;  2Y0J A;  4AJF A;  5K1I A;  2OVV A;  1OYN A;  3JSI A;  3ITM A;  3K3E A;  3W5E A;  5C1W A;  3BJC A;  2QYM A;  3TVX A;  3SL4 A;  3K4S A;  1XM6 A;  3G4K A;  3IAD A;  4GH6 A;  3V94 A;  3ITU A;  1XMU B;  4MRW A;  2H40 A;  4NPV A;  3JWQ A;  1XOQ A;  4XY2 A;  4MD6 A;  2OUV A;  3N3Z A;  2FM0 A;  2QYK A;  4YQH A;  3ECN A;  4AJD A;  1TBB A;  4WN1 A;  5I2R A;  4OGB A;  5DH5 A;  2OUR A;  1Y2K A;  1TAZ A;  4HTX A;  1TBF A;  3HDZ A;  4QGE A;  5EDI B;  4MSC A;  3WD9 A;  3SHY A;  1Y2D A;  3HQY A;  5EDG B;  1XOR A;  2YY2 A;  4PHW A;  2WEY A;  4P0N A;  3I8V A;  1XOS A;  2HD1 A;  1UHO A;  1XM4 A;  3D3P A;  3GWT A;  3HR1 A;  3LXG A;  5EDH A;  3ECM A;  4HEU A;  4DFF A;  1XON A;  1Z1L A;  5DH4 A;  2PW3 A;  1F0J A;  5C28 A;  1XMY A;  5C2H A;  1XOT A;  2QYL A;  4LLP A;  2H42 A;  3SNI A;  2OUQ A;  4P1R A;  1Y2C A;  1SO2 A;  4WCU A;  4DDL A;  4NW7 A;  4G2W A;  1TB5 A;  1RO9 A;  3WS8 A;  1UDT A;  3QPO A;  1Q9M A;  4LM2 A;  4MUW A;  3O0J A;  1PTW A;  4Y8C A;  3G45 A;  4MYQ A;  1Y2E A;  2OVY A;  3JWR A;  4OEW A;  3HMV A;  3WI2 A;  5B4L A;  2OUN A;  2FM5 A;  3QI3 A;  4LM1 A;  3LY2 A;  5EDE A;  4HF4 A;  1XOM A;  3IBJ A;  4LM3 A;  3HQW A;  5C29 A;  3DYN A;  1MKD A;  2OUY A;  3WYL A;  3G4G A;  3FRG A;  3UI7 A;  1Y2H A;  4LKQ A;  4NPW A;  3SN7 A;  3SL3 A;  4BBX A;  1XMU A;  1XN0 A;  4HTZ A;  4IA0 A;  4E90 A;  4ZO5 A;  4FCD A;  3G4L A;  4W1O A;  3SIE A;  4LLK A;  4LM4 A;  1T9R A;  1XLX A;  3WYK A;  3DYL A;  3G3N A;  4X0F A;  4G2J A;  1RKP A;  4LLJ A;  4C1I A;  5B4K A;  3KKT A;  3QI4 A;  3DYS A;  4I9Z A;  3HC8 A;  5EDI A;  5AXQ A;  3UUO A;  5B25 A;  4PM0 A;  3DYQ A;  5EDG A;  4G2L A;  4JIB A;  5K32 A;  4AJG A;  2OUU A;  4TPP A;  4MRZ A;  3G4I A;  1TB7 A;  5C2E A;  4MSH A;  1ZKL A;  2OUS A;  4G2Y A;  1ZKN A;  4MSN A;  4Y86 A;  5C2A A;  3DY8 A;  3SL5 A;  4D08 A;  4MSA A;  4KP6 A;  3O57 A;  2CHM A;  3O56 A;  3QPP A;  4FCB A;  3K3H A;  4PHL A;  5EDE B;  1XP0 A;  4MVH A;  1XOZ A;  4YS7 A;  2R8Q A;  3JSW A;  3WS9 A;  5K9R A;  3SL6 A;  3G58 A;  5AXP A;  4LLX A;  3IAK A;  1RO6 A;  3V9B A;  1XM4 B;  3B2R A;  1SOJ A; 
#chains in the Genus database with same CATH topology
 2H44 A;  4I15 A;  3V93 A;  4MS0 A;  4MSE A;  4AJM A;  3SL8 A;  4WZI A;  3QPN A;  2O8H A;  4Y87 A;  3TGE A;  2QYN A;  4TPM A;  1XMY B;  3HQZ A;  4OEX A;  2OUP A;  4LM0 A;  1UDU A;  1ROR A;  3TGG A;  4D09 A;  3WYM A;  1T9S A;  1Y2B A;  4AEL A;  1Y2J A;  3SNL A;  4Y2B A;  1XLZ A;  3SHZ A;  2Y0J A;  4AJF A;  5K1I A;  2OVV A;  1OYN A;  3JSI A;  3ITM A;  3K3E A;  3W5E A;  5C1W A;  3BJC A;  2QYM A;  3TVX A;  3SL4 A;  3K4S A;  1XM6 A;  3G4K A;  3IAD A;  4GH6 A;  3V94 A;  3ITU A;  1XMU B;  4MRW A;  2H40 A;  4NPV A;  3JWQ A;  1XOQ A;  4XY2 A;  4MD6 A;  2OUV A;  3N3Z A;  2FM0 A;  2QYK A;  4YQH A;  3ECN A;  4AJD A;  1TBB A;  4WN1 A;  5I2R A;  4OGB A;  5DH5 A;  2OUR A;  1Y2K A;  1TAZ A;  4HTX A;  1TBF A;  3HDZ A;  4QGE A;  5EDI B;  4MSC A;  3WD9 A;  3SHY A;  1Y2D A;  3HQY A;  5EDG B;  1XOR A;  2YY2 A;  4PHW A;  2WEY A;  4P0N A;  3I8V A;  1XOS A;  2HD1 A;  1UHO A;  1XM4 A;  3D3P A;  3GWT A;  3HR1 A;  3LXG A;  5EDH A;  3ECM A;  4HEU A;  4DFF A;  1XON A;  1Z1L A;  5DH4 A;  2PW3 A;  1F0J A;  5C28 A;  1XMY A;  5C2H A;  1XOT A;  2QYL A;  4LLP A;  2H42 A;  3SNI A;  2OUQ A;  4P1R A;  1Y2C A;  1SO2 A;  4WCU A;  4DDL A;  4NW7 A;  4G2W A;  1TB5 A;  1RO9 A;  3WS8 A;  1UDT A;  3QPO A;  1Q9M A;  4LM2 A;  4MUW A;  3O0J A;  1PTW A;  4Y8C A;  3G45 A;  4MYQ A;  1Y2E A;  2OVY A;  3JWR A;  4OEW A;  3HMV A;  3WI2 A;  5B4L A;  2OUN A;  2FM5 A;  3QI3 A;  4LM1 A;  3LY2 A;  5EDE A;  4HF4 A;  1XOM A;  3IBJ A;  4LM3 A;  3HQW A;  5C29 A;  3DYN A;  1MKD A;  2OUY A;  3WYL A;  3G4G A;  3FRG A;  3UI7 A;  1Y2H A;  4LKQ A;  4NPW A;  3SN7 A;  3SL3 A;  4BBX A;  1XMU A;  1XN0 A;  4HTZ A;  4IA0 A;  4E90 A;  4ZO5 A;  4FCD A;  3G4L A;  4W1O A;  3SIE A;  4LLK A;  4LM4 A;  1T9R A;  1XLX A;  3WYK A;  3DYL A;  3G3N A;  4X0F A;  4G2J A;  1RKP A;  4LLJ A;  4C1I A;  5B4K A;  3KKT A;  3QI4 A;  3DYS A;  4I9Z A;  3HC8 A;  5EDI A;  5AXQ A;  3UUO A;  5B25 A;  4PM0 A;  3DYQ A;  5EDG A;  4G2L A;  4JIB A;  5K32 A;  4AJG A;  2OUU A;  4TPP A;  4MRZ A;  3G4I A;  1TB7 A;  5C2E A;  4MSH A;  1ZKL A;  2OUS A;  4G2Y A;  1ZKN A;  4MSN A;  4Y86 A;  5C2A A;  3DY8 A;  3SL5 A;  4D08 A;  4MSA A;  4KP6 A;  3O57 A;  2CHM A;  3O56 A;  3QPP A;  4FCB A;  3K3H A;  4PHL A;  5EDE B;  1XP0 A;  4MVH A;  1XOZ A;  4YS7 A;  2R8Q A;  3JSW A;  3WS9 A;  5K9R A;  3SL6 A;  3G58 A;  5AXP A;  4LLX A;  3IAK A;  1RO6 A;  3V9B A;  1XM4 B;  3B2R A;  1SOJ A; 
#chains in the Genus database with same CATH homology
 2H44 A;  4I15 A;  3V93 A;  4MS0 A;  4MSE A;  4AJM A;  3SL8 A;  4WZI A;  3QPN A;  2O8H A;  4Y87 A;  3TGE A;  2QYN A;  4TPM A;  1XMY B;  3HQZ A;  4OEX A;  2OUP A;  4LM0 A;  1UDU A;  1ROR A;  3TGG A;  4D09 A;  3WYM A;  1T9S A;  1Y2B A;  4AEL A;  1Y2J A;  3SNL A;  4Y2B A;  1XLZ A;  3SHZ A;  2Y0J A;  4AJF A;  5K1I A;  2OVV A;  1OYN A;  3JSI A;  3ITM A;  3K3E A;  3W5E A;  5C1W A;  3BJC A;  2QYM A;  3TVX A;  3SL4 A;  3K4S A;  1XM6 A;  3G4K A;  3IAD A;  4GH6 A;  3V94 A;  3ITU A;  1XMU B;  4MRW A;  2H40 A;  4NPV A;  3JWQ A;  1XOQ A;  4XY2 A;  4MD6 A;  2OUV A;  3N3Z A;  2FM0 A;  2QYK A;  4YQH A;  3ECN A;  4AJD A;  1TBB A;  4WN1 A;  5I2R A;  4OGB A;  5DH5 A;  2OUR A;  1Y2K A;  1TAZ A;  4HTX A;  1TBF A;  3HDZ A;  4QGE A;  5EDI B;  4MSC A;  3WD9 A;  3SHY A;  1Y2D A;  3HQY A;  5EDG B;  1XOR A;  2YY2 A;  4PHW A;  2WEY A;  4P0N A;  3I8V A;  1XOS A;  2HD1 A;  1UHO A;  1XM4 A;  3D3P A;  3GWT A;  3HR1 A;  3LXG A;  5EDH A;  3ECM A;  4HEU A;  4DFF A;  1XON A;  1Z1L A;  5DH4 A;  2PW3 A;  1F0J A;  5C28 A;  1XMY A;  5C2H A;  1XOT A;  2QYL A;  4LLP A;  2H42 A;  3SNI A;  2OUQ A;  4P1R A;  1Y2C A;  1SO2 A;  4WCU A;  4DDL A;  4NW7 A;  4G2W A;  1TB5 A;  1RO9 A;  3WS8 A;  1UDT A;  3QPO A;  1Q9M A;  4LM2 A;  4MUW A;  3O0J A;  1PTW A;  4Y8C A;  3G45 A;  4MYQ A;  1Y2E A;  2OVY A;  3JWR A;  4OEW A;  3HMV A;  3WI2 A;  5B4L A;  2OUN A;  2FM5 A;  3QI3 A;  4LM1 A;  3LY2 A;  5EDE A;  4HF4 A;  1XOM A;  3IBJ A;  4LM3 A;  3HQW A;  5C29 A;  3DYN A;  1MKD A;  2OUY A;  3WYL A;  3G4G A;  3FRG A;  3UI7 A;  1Y2H A;  4LKQ A;  4NPW A;  3SN7 A;  3SL3 A;  4BBX A;  1XMU A;  1XN0 A;  4HTZ A;  4IA0 A;  4E90 A;  4ZO5 A;  4FCD A;  3G4L A;  4W1O A;  3SIE A;  4LLK A;  4LM4 A;  1T9R A;  1XLX A;  3WYK A;  3DYL A;  3G3N A;  4X0F A;  4G2J A;  1RKP A;  4LLJ A;  4C1I A;  5B4K A;  3KKT A;  3QI4 A;  3DYS A;  4I9Z A;  3HC8 A;  5EDI A;  5AXQ A;  3UUO A;  5B25 A;  4PM0 A;  3DYQ A;  5EDG A;  4G2L A;  4JIB A;  5K32 A;  4AJG A;  2OUU A;  4TPP A;  4MRZ A;  3G4I A;  1TB7 A;  5C2E A;  4MSH A;  1ZKL A;  2OUS A;  4G2Y A;  1ZKN A;  4MSN A;  4Y86 A;  5C2A A;  3DY8 A;  3SL5 A;  4D08 A;  4MSA A;  4KP6 A;  3O57 A;  2CHM A;  3O56 A;  3QPP A;  4FCB A;  3K3H A;  4PHL A;  5EDE B;  1XP0 A;  4MVH A;  1XOZ A;  4YS7 A;  2R8Q A;  3JSW A;  3WS9 A;  5K9R A;  3SL6 A;  3G58 A;  5AXP A;  4LLX A;  3IAK A;  1RO6 A;  3V9B A;  1XM4 B;  3B2R A;  1SOJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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