4Z70A

Crystal structure of inorganic pyrophosphatase from mycobacterium tuberculosis in complex with ca ions
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
160
structure length
160
Chain Sequence
AMQFDVTIEIPKGQRNKYEVDHETGRVRLDRYLYTPMAYPTDYGFIEDTLGDDGDPLDALVLLPQPVFPGVLVAARPVGMFRMVDEHGGDDKVLCVPAGDPRWDHVQDIGDVPAFELDAIKHFFVHYKDLEPGKFVKAADWVDRAEAEAEVQRSVERFKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and computational dissection of the catalytic mechanism of the inorganic pyrophosphatase from Mycobacterium tuberculosis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
molecule keywords Inorganic pyrophosphatase
total genus 45
structure length 160
sequence length 160
chains with identical sequence B, C
ec nomenclature ec 3.6.1.1: Inorganic diphosphatase.
pdb deposition date 2015-04-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00719 Pyrophosphatase Inorganic pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.80.10 Alpha Beta Alpha-Beta Complex Inorganic Pyrophosphatase Inorganic pyrophosphatase 4z70A00
1INOA 1SXVA 2AU7A 3Q5VA 4QLZA 2IK9A 4QMBA 3R5UA 1HUKA 1E6AA 3D53A 2EIPA 5TEAA 1M38A 2IK0A 4Z73A 1MJWA 4Z70A 1WGJA 4LUGA 3I4QA 1IGPA 1I6TA 1I40A 3Q4WA 8PRKA 2AU9A 3Q3LA 3R5VA 1YGZA 4XELA 1WGIA 3D63A 1WCFA 3GVFA 2BQYA 1FAJA 2UXSA 4Z74A 3FQ3A 117EA 1JFDA 2IK7A 2AU8A 3EMJA 3SW5A 1UDEA 3EJ2A 5KDEA 1QEZA 2IHPA 3R6EA 4ECPA 4Z72A 1OBWA 2IK4A 3I98A 1PYPA 4Z71A 1E9GA 4UM4A 3Q46A 2AUUA 1MJXA 1MJYA 3TR4A 2IK6A 5H4FA 1TWLA 3EIYA 3EJ0A 2IK2A 3LD3A 5KDFA 3LO0A 1HUJA 1IPWA 1YPPA 2IK1A 1MJZA 2PRDA 3EIZA 2BQXA 2AU6A
chains in the Genus database with same CATH superfamily
1INOA 1SXVA 2AU7A 3Q5VA 4QLZA 2IK9A 4QMBA 3R5UA 1HUKA 1E6AA 3D53A 2EIPA 5TEAA 1M38A 2IK0A 4Z73A 1MJWA 4Z70A 1WGJA 4LUGA 3I4QA 1IGPA 1I6TA 1I40A 3Q4WA 8PRKA 2AU9A 3Q3LA 3R5VA 1YGZA 4XELA 1WGIA 3D63A 1WCFA 3GVFA 2BQYA 1FAJA 2UXSA 4Z74A 3FQ3A 117EA 1JFDA 2IK7A 2AU8A 3EMJA 3SW5A 1UDEA 3EJ2A 5KDEA 1QEZA 2IHPA 3R6EA 4ECPA 4Z72A 1OBWA 2IK4A 3I98A 1PYPA 4Z71A 1E9GA 4UM4A 3Q46A 2AUUA 1MJXA 1MJYA 3TR4A 2IK6A 5H4FA 1TWLA 3EIYA 3EJ0A 2IK2A 3LD3A 5KDFA 3LO0A 1HUJA 1IPWA 1YPPA 2IK1A 1MJZA 2PRDA 3EIZA 2BQXA 2AU6A
chains in the Genus database with same CATH topology
1INOA 1SXVA 2AU7A 3Q5VA 4QLZA 2IK9A 4QMBA 3R5UA 1HUKA 1E6AA 3D53A 2EIPA 5TEAA 1M38A 2IK0A 4Z73A 1MJWA 4Z70A 1WGJA 4LUGA 3I4QA 1IGPA 1I6TA 1I40A 3Q4WA 8PRKA 2AU9A 3Q3LA 3R5VA 1YGZA 4XELA 1WGIA 3D63A 1WCFA 3GVFA 2BQYA 1FAJA 2UXSA 4Z74A 3FQ3A 117EA 1JFDA 2IK7A 2AU8A 3EMJA 3SW5A 1UDEA 3EJ2A 5KDEA 1QEZA 2IHPA 3R6EA 4ECPA 4Z72A 1OBWA 2IK4A 3I98A 1PYPA 4Z71A 1E9GA 4UM4A 3Q46A 2AUUA 1MJXA 1MJYA 3TR4A 2IK6A 5H4FA 1TWLA 3EIYA 3EJ0A 2IK2A 3LD3A 5KDFA 3LO0A 1HUJA 1IPWA 1YPPA 2IK1A 1MJZA 2PRDA 3EIZA 2BQXA 2AU6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1INO A;  1SXV A;  2AU7 A;  3Q5V A;  4QLZ A;  2IK9 A;  4QMB A;  3R5U A;  1HUK A;  1E6A A;  3D53 A;  2EIP A;  5TEA A;  1M38 A;  2IK0 A;  4Z73 A;  1MJW A;  4Z70 A;  1WGJ A;  4LUG A;  3I4Q A;  1IGP A;  1I6T A;  1I40 A;  3Q4W A;  8PRK A;  2AU9 A;  3Q3L A;  3R5V A;  1YGZ A;  4XEL A;  1WGI A;  3D63 A;  1WCF A;  3GVF A;  2BQY A;  1FAJ A;  2UXS A;  4Z74 A;  3FQ3 A;  117E A;  1JFD A;  2IK7 A;  2AU8 A;  3EMJ A;  3SW5 A;  1UDE A;  3EJ2 A;  5KDE A;  1QEZ A;  2IHP A;  3R6E A;  4ECP A;  4Z72 A;  1OBW A;  2IK4 A;  3I98 A;  1PYP A;  4Z71 A;  1E9G A;  4UM4 A;  3Q46 A;  2AUU A;  1MJX A;  1MJY A;  3TR4 A;  2IK6 A;  5H4F A;  1TWL A;  3EIY A;  3EJ0 A;  2IK2 A;  3LD3 A;  5KDF A;  3LO0 A;  1HUJ A;  1IPW A;  1YPP A;  2IK1 A;  1MJZ A;  2PRD A;  3EIZ A;  2BQX A;  2AU6 A; 
#chains in the Genus database with same CATH topology
 1INO A;  1SXV A;  2AU7 A;  3Q5V A;  4QLZ A;  2IK9 A;  4QMB A;  3R5U A;  1HUK A;  1E6A A;  3D53 A;  2EIP A;  5TEA A;  1M38 A;  2IK0 A;  4Z73 A;  1MJW A;  4Z70 A;  1WGJ A;  4LUG A;  3I4Q A;  1IGP A;  1I6T A;  1I40 A;  3Q4W A;  8PRK A;  2AU9 A;  3Q3L A;  3R5V A;  1YGZ A;  4XEL A;  1WGI A;  3D63 A;  1WCF A;  3GVF A;  2BQY A;  1FAJ A;  2UXS A;  4Z74 A;  3FQ3 A;  117E A;  1JFD A;  2IK7 A;  2AU8 A;  3EMJ A;  3SW5 A;  1UDE A;  3EJ2 A;  5KDE A;  1QEZ A;  2IHP A;  3R6E A;  4ECP A;  4Z72 A;  1OBW A;  2IK4 A;  3I98 A;  1PYP A;  4Z71 A;  1E9G A;  4UM4 A;  3Q46 A;  2AUU A;  1MJX A;  1MJY A;  3TR4 A;  2IK6 A;  5H4F A;  1TWL A;  3EIY A;  3EJ0 A;  2IK2 A;  3LD3 A;  5KDF A;  3LO0 A;  1HUJ A;  1IPW A;  1YPP A;  2IK1 A;  1MJZ A;  2PRD A;  3EIZ A;  2BQX A;  2AU6 A; 
#chains in the Genus database with same CATH homology
 1INO A;  1SXV A;  2AU7 A;  3Q5V A;  4QLZ A;  2IK9 A;  4QMB A;  3R5U A;  1HUK A;  1E6A A;  3D53 A;  2EIP A;  5TEA A;  1M38 A;  2IK0 A;  4Z73 A;  1MJW A;  4Z70 A;  1WGJ A;  4LUG A;  3I4Q A;  1IGP A;  1I6T A;  1I40 A;  3Q4W A;  8PRK A;  2AU9 A;  3Q3L A;  3R5V A;  1YGZ A;  4XEL A;  1WGI A;  3D63 A;  1WCF A;  3GVF A;  2BQY A;  1FAJ A;  2UXS A;  4Z74 A;  3FQ3 A;  117E A;  1JFD A;  2IK7 A;  2AU8 A;  3EMJ A;  3SW5 A;  1UDE A;  3EJ2 A;  5KDE A;  1QEZ A;  2IHP A;  3R6E A;  4ECP A;  4Z72 A;  1OBW A;  2IK4 A;  3I98 A;  1PYP A;  4Z71 A;  1E9G A;  4UM4 A;  3Q46 A;  2AUU A;  1MJX A;  1MJY A;  3TR4 A;  2IK6 A;  5H4F A;  1TWL A;  3EIY A;  3EJ0 A;  2IK2 A;  3LD3 A;  5KDF A;  3LO0 A;  1HUJ A;  1IPW A;  1YPP A;  2IK1 A;  1MJZ A;  2PRD A;  3EIZ A;  2BQX A;  2AU6 A; 
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