4Z73A

Crystal structure of inorganic pyrophosphatase from mycobacterium tuberculosis in complex with a phosphate ion and an inorganic pyrophosphate
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
160
structure length
160
Chain Sequence
AMQFDVTIEIPKGQRNKYEVDHETGRVRLDRYLYTPMAYPTDYGFIEDTLGDDGDPLDALVLLPQPVFPGVLVAARPVGMFRMVDEHGGDDKVLCVPAGDPRWDHVQDIGDVPAFELDAIKHFFVHYKDLEPGKFVKAADWVDRAEAEAEVQRSVERFKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and computational dissection of the catalytic mechanism of the inorganic pyrophosphatase from Mycobacterium tuberculosis.
pubmed doi rcsb
molecule keywords Inorganic pyrophosphatase
molecule tags Hydrolase
source organism Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
total genus 36
structure length 160
sequence length 160
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L
ec nomenclature ec 3.6.1.1: Inorganic diphosphatase.
pdb deposition date 2015-04-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00719 Pyrophosphatase Inorganic pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.80.10 Alpha Beta Alpha-Beta Complex Inorganic Pyrophosphatase Inorganic pyrophosphatase 4z73A00
1IGPA 3D63A 5KDEA 1SXVA 3Q4WA 3I4QA 3Q5VA 1OBWA 2EIPA 2AU7A 2UXSA 3EJ2A 4XELA 3EJ0A 5TEAA 2IK0A 3GVFA 1QEZA 3FQ3A 4Z74A 2IK1A 4Z71A 1MJZA 4QMBA 5H4FA 3I98A 2AU8A 2IK9A 1MJYA 3R5VA 1M38A 3EMJA 1TWLA 2AUUA 1YPPA 1JFDA 2IK4A 1UDEA 3EIYA 2IK6A 2BQXA 2AU9A 1IPWA 1I6TA 1WCFA 1INOA 1E6AA 1FAJA 4Z72A 2BQYA 4LUGA 4Z73A 3TR4A 2PRDA 3D53A 3SW5A 1PYPA 2AU6A 5KDFA 3LO0A 3Q46A 8PRKA 2IHPA 4UM4A 3EIZA 4ECPA 1MJXA 117EA 1HUJA 4QLZA 1WGIA 1HUKA 3R5UA 3R6EA 2IK2A 1MJWA 1WGJA 1E9GA 1YGZA 3LD3A 1I40A 2IK7A 3Q3LA 4Z70A
chains in the Genus database with same CATH superfamily
1IGPA 3D63A 5KDEA 1SXVA 3Q4WA 3I4QA 3Q5VA 1OBWA 2EIPA 2AU7A 2UXSA 3EJ2A 4XELA 3EJ0A 5TEAA 2IK0A 3GVFA 1QEZA 3FQ3A 4Z74A 2IK1A 4Z71A 1MJZA 4QMBA 5H4FA 3I98A 2AU8A 2IK9A 1MJYA 3R5VA 1M38A 3EMJA 1TWLA 2AUUA 1YPPA 1JFDA 2IK4A 1UDEA 3EIYA 2IK6A 2BQXA 2AU9A 1IPWA 1I6TA 1WCFA 1INOA 1E6AA 1FAJA 4Z72A 2BQYA 4LUGA 4Z73A 3TR4A 2PRDA 3D53A 3SW5A 1PYPA 2AU6A 5KDFA 3LO0A 3Q46A 8PRKA 2IHPA 4UM4A 3EIZA 4ECPA 1MJXA 117EA 1HUJA 4QLZA 1WGIA 1HUKA 3R5UA 3R6EA 2IK2A 1MJWA 1WGJA 1E9GA 1YGZA 3LD3A 1I40A 2IK7A 3Q3LA 4Z70A
chains in the Genus database with same CATH topology
1IGPA 3D63A 5KDEA 1SXVA 3Q4WA 3I4QA 3Q5VA 1OBWA 2EIPA 2AU7A 2UXSA 3EJ2A 4XELA 3EJ0A 5TEAA 2IK0A 3GVFA 1QEZA 3FQ3A 4Z74A 2IK1A 4Z71A 1MJZA 4QMBA 5H4FA 3I98A 2AU8A 2IK9A 1MJYA 3R5VA 1M38A 3EMJA 1TWLA 2AUUA 1YPPA 1JFDA 2IK4A 1UDEA 3EIYA 2IK6A 2BQXA 2AU9A 1IPWA 1I6TA 1WCFA 1INOA 1E6AA 1FAJA 4Z72A 2BQYA 4LUGA 4Z73A 3TR4A 2PRDA 3D53A 3SW5A 1PYPA 2AU6A 5KDFA 3LO0A 3Q46A 8PRKA 2IHPA 4UM4A 3EIZA 4ECPA 1MJXA 117EA 1HUJA 4QLZA 1WGIA 1HUKA 3R5UA 3R6EA 2IK2A 1MJWA 1WGJA 1E9GA 1YGZA 3LD3A 1I40A 2IK7A 3Q3LA 4Z70A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IGP A;  3D63 A;  5KDE A;  1SXV A;  3Q4W A;  3I4Q A;  3Q5V A;  1OBW A;  2EIP A;  2AU7 A;  2UXS A;  3EJ2 A;  4XEL A;  3EJ0 A;  5TEA A;  2IK0 A;  3GVF A;  1QEZ A;  3FQ3 A;  4Z74 A;  2IK1 A;  4Z71 A;  1MJZ A;  4QMB A;  5H4F A;  3I98 A;  2AU8 A;  2IK9 A;  1MJY A;  3R5V A;  1M38 A;  3EMJ A;  1TWL A;  2AUU A;  1YPP A;  1JFD A;  2IK4 A;  1UDE A;  3EIY A;  2IK6 A;  2BQX A;  2AU9 A;  1IPW A;  1I6T A;  1WCF A;  1INO A;  1E6A A;  1FAJ A;  4Z72 A;  2BQY A;  4LUG A;  4Z73 A;  3TR4 A;  2PRD A;  3D53 A;  3SW5 A;  1PYP A;  2AU6 A;  5KDF A;  3LO0 A;  3Q46 A;  8PRK A;  2IHP A;  4UM4 A;  3EIZ A;  4ECP A;  1MJX A;  117E A;  1HUJ A;  4QLZ A;  1WGI A;  1HUK A;  3R5U A;  3R6E A;  2IK2 A;  1MJW A;  1WGJ A;  1E9G A;  1YGZ A;  3LD3 A;  1I40 A;  2IK7 A;  3Q3L A;  4Z70 A; 
#chains in the Genus database with same CATH topology
 1IGP A;  3D63 A;  5KDE A;  1SXV A;  3Q4W A;  3I4Q A;  3Q5V A;  1OBW A;  2EIP A;  2AU7 A;  2UXS A;  3EJ2 A;  4XEL A;  3EJ0 A;  5TEA A;  2IK0 A;  3GVF A;  1QEZ A;  3FQ3 A;  4Z74 A;  2IK1 A;  4Z71 A;  1MJZ A;  4QMB A;  5H4F A;  3I98 A;  2AU8 A;  2IK9 A;  1MJY A;  3R5V A;  1M38 A;  3EMJ A;  1TWL A;  2AUU A;  1YPP A;  1JFD A;  2IK4 A;  1UDE A;  3EIY A;  2IK6 A;  2BQX A;  2AU9 A;  1IPW A;  1I6T A;  1WCF A;  1INO A;  1E6A A;  1FAJ A;  4Z72 A;  2BQY A;  4LUG A;  4Z73 A;  3TR4 A;  2PRD A;  3D53 A;  3SW5 A;  1PYP A;  2AU6 A;  5KDF A;  3LO0 A;  3Q46 A;  8PRK A;  2IHP A;  4UM4 A;  3EIZ A;  4ECP A;  1MJX A;  117E A;  1HUJ A;  4QLZ A;  1WGI A;  1HUK A;  3R5U A;  3R6E A;  2IK2 A;  1MJW A;  1WGJ A;  1E9G A;  1YGZ A;  3LD3 A;  1I40 A;  2IK7 A;  3Q3L A;  4Z70 A; 
#chains in the Genus database with same CATH homology
 1IGP A;  3D63 A;  5KDE A;  1SXV A;  3Q4W A;  3I4Q A;  3Q5V A;  1OBW A;  2EIP A;  2AU7 A;  2UXS A;  3EJ2 A;  4XEL A;  3EJ0 A;  5TEA A;  2IK0 A;  3GVF A;  1QEZ A;  3FQ3 A;  4Z74 A;  2IK1 A;  4Z71 A;  1MJZ A;  4QMB A;  5H4F A;  3I98 A;  2AU8 A;  2IK9 A;  1MJY A;  3R5V A;  1M38 A;  3EMJ A;  1TWL A;  2AUU A;  1YPP A;  1JFD A;  2IK4 A;  1UDE A;  3EIY A;  2IK6 A;  2BQX A;  2AU9 A;  1IPW A;  1I6T A;  1WCF A;  1INO A;  1E6A A;  1FAJ A;  4Z72 A;  2BQY A;  4LUG A;  4Z73 A;  3TR4 A;  2PRD A;  3D53 A;  3SW5 A;  1PYP A;  2AU6 A;  5KDF A;  3LO0 A;  3Q46 A;  8PRK A;  2IHP A;  4UM4 A;  3EIZ A;  4ECP A;  1MJX A;  117E A;  1HUJ A;  4QLZ A;  1WGI A;  1HUK A;  3R5U A;  3R6E A;  2IK2 A;  1MJW A;  1WGJ A;  1E9G A;  1YGZ A;  3LD3 A;  1I40 A;  2IK7 A;  3Q3L A;  4Z70 A; 
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