4Z7FA

Crystal structure of folt bound with folic acid
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
168
structure length
163
Chain Sequence
GTKSIALMGVLIAVVVVFSRFFAYETTFLKISFTFIPESLIGMIFGPFWAGIGTAVADVVGMLLFPKAGYFPGFTLNAFLAGAIYGYFYYKKEMTWQRVILATLLVTVLINIILTPLWLSLMYGVNLANFAWWVPRLIKTVIFFPIQVIATYYLGNKLFGKPL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of FolT in substrate-bound and substrate-released conformations reveal a gating mechanism for ECF transporters
pubmed doi rcsb
molecule keywords Folate ECF transporter
molecule tags Transport protein
source organism Enterococcus faecalis (strain atcc 700802 / v583)
total genus 48
structure length 163
sequence length 168
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2015-04-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF12822 ECF_trnsprt ECF transporter, substrate-specific component
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1760.20 Mainly Alpha Orthogonal Bundle Arp2/3 complex 21 kDa subunit ARPC3 Arp2/3 complex 21 kDa subunit ARPC3 4z7fA00
4Z7FA 5JSZC 4MHWA 4HUQS 4M58A 4M5BA 4M5CA 5KBWA 3P5NA 4POPA 3RLBA 4MUUA 4N4DA 4MESA 5D0YA 4HZUS 4RFSS 4POVA 5KC0A 5KC4A 5D3MC 4TKRA 4DVEA
chains in the Genus database with same CATH superfamily
2P9NE 2P9PE 4Z7FA 5JSZC 3DXKE 4MHWA 4HUQS 4TKRA 4M58A 1K8KE 4M5BA 4M5CA 3ULEE 5KBWA 2P9SE 3P5NA 2P9UE 4POPA 3RLBA 4MUUA 2P9LE 3UKUE 4N4DA 3RSEE 1U2VE 3UKRE 4MESA 4XEIE 5D0YA 2P9IE 4JD2E 4HZUS 4RFSS 4POVA 2P9KE 3DXME 5KC0A 5KC4A 5D3MC 1TYQE 4DVEA
chains in the Genus database with same CATH topology
4Z7FA 5JSZC 4MHWA 4HUQS 4M58A 4M5BA 4M5CA 5KBWA 3P5NA 4POPA 3RLBA 4MUUA 4N4DA 4MESA 5D0YA 4HZUS 4RFSS 4POVA 5KC0A 5KC4A 5D3MC 4TKRA 4DVEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z7F A;  5JSZ C;  4MHW A;  4HUQ S;  4M58 A;  4M5B A;  4M5C A;  5KBW A;  3P5N A;  4POP A;  3RLB A;  4MUU A;  4N4D A;  4MES A;  5D0Y A;  4HZU S;  4RFS S;  4POV A;  5KC0 A;  5KC4 A;  5D3M C;  4TKR A;  4DVE A; 
#chains in the Genus database with same CATH topology
 2P9N E;  2P9P E;  4Z7F A;  5JSZ C;  3DXK E;  4MHW A;  4HUQ S;  4TKR A;  4M58 A;  1K8K E;  4M5B A;  4M5C A;  3ULE E;  5KBW A;  2P9S E;  3P5N A;  2P9U E;  4POP A;  3RLB A;  4MUU A;  2P9L E;  3UKU E;  4N4D A;  3RSE E;  1U2V E;  3UKR E;  4MES A;  4XEI E;  5D0Y A;  2P9I E;  4JD2 E;  4HZU S;  4RFS S;  4POV A;  2P9K E;  3DXM E;  5KC0 A;  5KC4 A;  5D3M C;  1TYQ E;  4DVE A; 
#chains in the Genus database with same CATH homology
 4Z7F A;  5JSZ C;  4MHW A;  4HUQ S;  4M58 A;  4M5B A;  4M5C A;  5KBW A;  3P5N A;  4POP A;  3RLB A;  4MUU A;  4N4D A;  4MES A;  5D0Y A;  4HZU S;  4RFS S;  4POV A;  5KC0 A;  5KC4 A;  5D3M C;  4TKR A;  4DVE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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