4ECPA

X-ray crystal structure of inorganic pyrophosphate ppa from mycobacterium leprae
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
160
structure length
160
Chain Sequence
MVQFDVTIEIPKGQRNKYEVDHKTGRVRLDRYLYTPMAYPTDYGFIEDTLGEDGDPLDALVLLPEPLFPGVLVEARPVGMFRMVDEHGGDDKVLCVPVNDHRWDHIHGIIDVPTFELDAIKHFFVHYKDLEPGKFVKAADWVGRDEAEAEVQRSVERFKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray crystal structure of Inorganic Pyrophosphate PPA from Mycobacterium leprae
rcsb
molecule tags Hydrolase
source organism Mycobacterium leprae
molecule keywords Inorganic pyrophosphatase
total genus 41
structure length 160
sequence length 160
chains with identical sequence B
ec nomenclature ec 3.6.1.1: Inorganic diphosphatase.
pdb deposition date 2012-03-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00719 Pyrophosphatase Inorganic pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.80.10 Alpha Beta Alpha-Beta Complex Inorganic Pyrophosphatase Inorganic pyrophosphatase 4ecpA00
1IPWA 3GVFA 1YPPA 2IK9A 2AU8A 3I4QA 4QMBA 8PRKA 3R5UA 2AUUA 1WGJA 1E6AA 2IHPA 4Z70A 1TWLA 3Q5VA 2UXSA 1FAJA 1PYPA 2IK0A 3D63A 1SXVA 3LD3A 4Z74A 5TEAA 1YGZA 3I98A 4Z71A 1I6TA 1JFDA 1I40A 1WCFA 3TR4A 2IK4A 2IK6A 3EMJA 4XELA 2BQYA 2AU6A 1MJXA 3LO0A 1HUKA 4LUGA 3Q3LA 2AU9A 1M38A 1QEZA 2PRDA 4Z72A 3EJ2A 1MJZA 3Q4WA 2IK2A 1MJYA 2IK1A 1E9GA 3D53A 4Z73A 1INOA 3FQ3A 5KDEA 3EJ0A 1WGIA 3EIYA 3Q46A 1HUJA 1OBWA 4ECPA 3EIZA 3R6EA 5KDFA 1IGPA 2EIPA 2AU7A 4QLZA 117EA 2BQXA 5H4FA 3R5VA 1MJWA 1UDEA 2IK7A 4UM4A 3SW5A
chains in the Genus database with same CATH superfamily
1IPWA 3GVFA 1YPPA 2IK9A 2AU8A 3I4QA 4QMBA 8PRKA 3R5UA 2AUUA 1WGJA 1E6AA 2IHPA 4Z70A 1TWLA 3Q5VA 2UXSA 1FAJA 1PYPA 2IK0A 3D63A 1SXVA 3LD3A 4Z74A 5TEAA 1YGZA 3I98A 4Z71A 1I6TA 1JFDA 1I40A 1WCFA 3TR4A 2IK4A 2IK6A 3EMJA 4XELA 2BQYA 2AU6A 1MJXA 3LO0A 1HUKA 4LUGA 3Q3LA 2AU9A 1M38A 1QEZA 2PRDA 4Z72A 3EJ2A 1MJZA 3Q4WA 2IK2A 1MJYA 2IK1A 1E9GA 3D53A 4Z73A 1INOA 3FQ3A 5KDEA 3EJ0A 1WGIA 3EIYA 3Q46A 1HUJA 1OBWA 4ECPA 3EIZA 3R6EA 5KDFA 1IGPA 2EIPA 2AU7A 4QLZA 117EA 2BQXA 5H4FA 3R5VA 1MJWA 1UDEA 2IK7A 4UM4A 3SW5A
chains in the Genus database with same CATH topology
1IPWA 3GVFA 1YPPA 2IK9A 2AU8A 3I4QA 4QMBA 8PRKA 3R5UA 2AUUA 1WGJA 1E6AA 2IHPA 4Z70A 1TWLA 3Q5VA 2UXSA 1FAJA 1PYPA 2IK0A 3D63A 1SXVA 3LD3A 4Z74A 5TEAA 1YGZA 3I98A 4Z71A 1I6TA 1JFDA 1I40A 1WCFA 3TR4A 2IK4A 2IK6A 3EMJA 4XELA 2BQYA 2AU6A 1MJXA 3LO0A 1HUKA 4LUGA 3Q3LA 2AU9A 1M38A 1QEZA 2PRDA 4Z72A 3EJ2A 1MJZA 3Q4WA 2IK2A 1MJYA 2IK1A 1E9GA 3D53A 4Z73A 1INOA 3FQ3A 5KDEA 3EJ0A 1WGIA 3EIYA 3Q46A 1HUJA 1OBWA 4ECPA 3EIZA 3R6EA 5KDFA 1IGPA 2EIPA 2AU7A 4QLZA 117EA 2BQXA 5H4FA 3R5VA 1MJWA 1UDEA 2IK7A 4UM4A 3SW5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IPW A;  3GVF A;  1YPP A;  2IK9 A;  2AU8 A;  3I4Q A;  4QMB A;  8PRK A;  3R5U A;  2AUU A;  1WGJ A;  1E6A A;  2IHP A;  4Z70 A;  1TWL A;  3Q5V A;  2UXS A;  1FAJ A;  1PYP A;  2IK0 A;  3D63 A;  1SXV A;  3LD3 A;  4Z74 A;  5TEA A;  1YGZ A;  3I98 A;  4Z71 A;  1I6T A;  1JFD A;  1I40 A;  1WCF A;  3TR4 A;  2IK4 A;  2IK6 A;  3EMJ A;  4XEL A;  2BQY A;  2AU6 A;  1MJX A;  3LO0 A;  1HUK A;  4LUG A;  3Q3L A;  2AU9 A;  1M38 A;  1QEZ A;  2PRD A;  4Z72 A;  3EJ2 A;  1MJZ A;  3Q4W A;  2IK2 A;  1MJY A;  2IK1 A;  1E9G A;  3D53 A;  4Z73 A;  1INO A;  3FQ3 A;  5KDE A;  3EJ0 A;  1WGI A;  3EIY A;  3Q46 A;  1HUJ A;  1OBW A;  4ECP A;  3EIZ A;  3R6E A;  5KDF A;  1IGP A;  2EIP A;  2AU7 A;  4QLZ A;  117E A;  2BQX A;  5H4F A;  3R5V A;  1MJW A;  1UDE A;  2IK7 A;  4UM4 A;  3SW5 A; 
#chains in the Genus database with same CATH topology
 1IPW A;  3GVF A;  1YPP A;  2IK9 A;  2AU8 A;  3I4Q A;  4QMB A;  8PRK A;  3R5U A;  2AUU A;  1WGJ A;  1E6A A;  2IHP A;  4Z70 A;  1TWL A;  3Q5V A;  2UXS A;  1FAJ A;  1PYP A;  2IK0 A;  3D63 A;  1SXV A;  3LD3 A;  4Z74 A;  5TEA A;  1YGZ A;  3I98 A;  4Z71 A;  1I6T A;  1JFD A;  1I40 A;  1WCF A;  3TR4 A;  2IK4 A;  2IK6 A;  3EMJ A;  4XEL A;  2BQY A;  2AU6 A;  1MJX A;  3LO0 A;  1HUK A;  4LUG A;  3Q3L A;  2AU9 A;  1M38 A;  1QEZ A;  2PRD A;  4Z72 A;  3EJ2 A;  1MJZ A;  3Q4W A;  2IK2 A;  1MJY A;  2IK1 A;  1E9G A;  3D53 A;  4Z73 A;  1INO A;  3FQ3 A;  5KDE A;  3EJ0 A;  1WGI A;  3EIY A;  3Q46 A;  1HUJ A;  1OBW A;  4ECP A;  3EIZ A;  3R6E A;  5KDF A;  1IGP A;  2EIP A;  2AU7 A;  4QLZ A;  117E A;  2BQX A;  5H4F A;  3R5V A;  1MJW A;  1UDE A;  2IK7 A;  4UM4 A;  3SW5 A; 
#chains in the Genus database with same CATH homology
 1IPW A;  3GVF A;  1YPP A;  2IK9 A;  2AU8 A;  3I4Q A;  4QMB A;  8PRK A;  3R5U A;  2AUU A;  1WGJ A;  1E6A A;  2IHP A;  4Z70 A;  1TWL A;  3Q5V A;  2UXS A;  1FAJ A;  1PYP A;  2IK0 A;  3D63 A;  1SXV A;  3LD3 A;  4Z74 A;  5TEA A;  1YGZ A;  3I98 A;  4Z71 A;  1I6T A;  1JFD A;  1I40 A;  1WCF A;  3TR4 A;  2IK4 A;  2IK6 A;  3EMJ A;  4XEL A;  2BQY A;  2AU6 A;  1MJX A;  3LO0 A;  1HUK A;  4LUG A;  3Q3L A;  2AU9 A;  1M38 A;  1QEZ A;  2PRD A;  4Z72 A;  3EJ2 A;  1MJZ A;  3Q4W A;  2IK2 A;  1MJY A;  2IK1 A;  1E9G A;  3D53 A;  4Z73 A;  1INO A;  3FQ3 A;  5KDE A;  3EJ0 A;  1WGI A;  3EIY A;  3Q46 A;  1HUJ A;  1OBW A;  4ECP A;  3EIZ A;  3R6E A;  5KDF A;  1IGP A;  2EIP A;  2AU7 A;  4QLZ A;  117E A;  2BQX A;  5H4F A;  3R5V A;  1MJW A;  1UDE A;  2IK7 A;  4UM4 A;  3SW5 A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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