4FCBA

Potent and selective phosphodiesterase 10a inhibitors
Total Genus 130
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
130
sequence length
322
structure length
322
Chain Sequence
MSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Novel triazines as potent and selective phosphodiesterase 10A inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase
total genus 130
structure length 322
sequence length 322
chains with identical sequence B
ec nomenclature ec 3.1.4.17: 3',5'-cyclic-nucleotide phosphodiesterase.
pdb deposition date 2012-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00233 PDEase_I 3'5'-cyclic nucleotide phosphodiesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1300.10 Mainly Alpha Orthogonal Bundle Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 4fcbA00
2QYMA 1RORA 1XMYB 4D08A 3WYKA 1F0JA 3DY8A 3D3PA 1Q9MA 1XOSA 4MSEA 4IA0A 3K3HA 5I2RA 3LY2A 4FCDA 1XP0A 3WS9A 1XMUA 3QPPA 3V93A 4LLJA 3TGEA 1Z1LA 3JWQA 3HDZA 4LM2A 3B2RA 3QPOA 1MKDA 4MD6A 4ZO5A 2OUPA 1XMUB 4PHWA 4Y8CA 3WYLA 4MVHA 4Y86A 5EDIA 2FM0A 2OVYA 2OUVA 4MRWA 3WS8A 5DH4A 4JIBA 1TBBA 4AELA 3G3NA 5EDEA 1PTWA 2QYLA 4KP6A 4PM0A 5EDIB 1XONA 2OUSA 1XORA 2Y0JA 4I15A 5C1WA 5K9RA 4LLXA 5EDEB 3UUOA 1UHOA 5C28A 4HTXA 3SL6A 3FRGA 4WCUA 4TPPA 4WN1A 3G45A 3V9BA 3DYSA 5DH5A 3SHYA 4Y87A 1T9RA 1TAZA 3QPNA 4GH6A 3IBJA 4W1OA 2HD1A 3WYMA 1XOMA 2WEYA 3SL8A 3SNIA 1SOJA 3IADA 3BJCA 1Y2HA 1OYNA 1Y2CA 2OUQA 3G4KA 3SL3A 3SN7A 1TB7A 1SO2A 4P0NA 2OUYA 4NW7A 4C1IA 1Y2KA 4MUWA 2YY2A 3JSIA 3N3ZA 3G58A 2FM5A 4LM4A 3DYQA 3WD9A 5C29A 4LKQA 4MS0A 2H42A 1RKPA 4DFFA 3O56A 4MYQA 3ITMA 3DYNA 3LXGA 3QI3A 4MSHA 3ITUA 1TBFA 4LM1A 2H44A 1XLXA 1T9SA 2R8QA 3JWRA 1Y2BA 4G2YA 3TGGA 3HMVA 4MSCA 1ZKLA 2QYKA 4P1RA 5B25A 1UDTA 3IAKA 3SHZA 5B4LA 1XOZA 4E90A 2O8HA 4BBXA 4AJDA 1TB5A 5C2HA 3G4GA 3HQYA 3JSWA 3W5EA 1Y2DA 3G4IA 4HF4A 3HQWA 1Y2JA 4YS7A 3K3EA 4LM0A 1XM6A 3I8VA 4QGEA 2OVVA 2OUNA 4LLKA 4DDLA 1XN0A 3SL5A 3QI4A 5AXPA 2H40A 5C2EA 1XM4A 4PHLA 4Y2BA 4HEUA 1ZKNA 4HTZA 3KKTA 4MRZA 4YQHA 3DYLA 5B4KA 3SNLA 5C2AA 5K1IA 3ECMA 1XM4B 4MSNA 4OEWA 4AJFA 4I9ZA 4AJMA 1UDUA 4TPMA 3WI2A 4LM3A 4XY2A 4G2JA 5K32A 2OURA 2QYNA 3G4LA 3HR1A 4FCBA 4MSAA 4G2WA 1XOTA 4NPWA 4D09A 2PW3A 4G2LA 5EDHA 3O0JA 4X0FA 4OGBA 3HC8A 3SL4A 3GWTA 5EDGA 4OEXA 1RO6A 1Y2EA 1XOQA 3UI7A 1XLZA 3HQZA 2OUUA 4NPVA 4LLPA 3TVXA 3V94A 3K4SA 1XMYA 3O57A 2CHMA 4WZIA 5EDGB 5AXQA 3SIEA 3ECNA 1RO9A 4AJGA
chains in the Genus database with same CATH superfamily
2QYMA 1RORA 1XMYB 4D08A 3WYKA 1F0JA 3DY8A 3D3PA 1Q9MA 1XOSA 4MSEA 4IA0A 3K3HA 5I2RA 3LY2A 4FCDA 1XP0A 3WS9A 1XMUA 3QPPA 3V93A 4LLJA 3TGEA 1Z1LA 3JWQA 3HDZA 4LM2A 3B2RA 3QPOA 1MKDA 4MD6A 4ZO5A 2OUPA 1XMUB 4PHWA 4Y8CA 3WYLA 4MVHA 4Y86A 5EDIA 2FM0A 2OVYA 2OUVA 4MRWA 3WS8A 5DH4A 4JIBA 1TBBA 4AELA 3G3NA 5EDEA 1PTWA 2QYLA 4KP6A 4PM0A 5EDIB 1XONA 2OUSA 1XORA 2Y0JA 4I15A 5C1WA 5K9RA 4LLXA 5EDEB 3UUOA 1UHOA 5C28A 4HTXA 3SL6A 3FRGA 4WCUA 4TPPA 4WN1A 3G45A 3V9BA 3DYSA 5DH5A 3SHYA 4Y87A 1T9RA 1TAZA 3QPNA 4GH6A 3IBJA 4W1OA 2HD1A 3WYMA 1XOMA 2WEYA 3SL8A 3SNIA 1SOJA 3IADA 3BJCA 1Y2HA 1OYNA 1Y2CA 2OUQA 3G4KA 3SL3A 3SN7A 1TB7A 1SO2A 4P0NA 2OUYA 4NW7A 4C1IA 1Y2KA 4MUWA 2YY2A 3JSIA 3N3ZA 3G58A 2FM5A 4LM4A 3DYQA 3WD9A 5C29A 4LKQA 4MS0A 2H42A 1RKPA 4DFFA 3O56A 4MYQA 3ITMA 3DYNA 3LXGA 3QI3A 4MSHA 3ITUA 1TBFA 4LM1A 2H44A 1XLXA 1T9SA 2R8QA 3JWRA 1Y2BA 4G2YA 3TGGA 3HMVA 4MSCA 1ZKLA 2QYKA 4P1RA 5B25A 1UDTA 3IAKA 3SHZA 5B4LA 1XOZA 4E90A 2O8HA 4BBXA 4AJDA 1TB5A 5C2HA 3G4GA 3HQYA 3JSWA 3W5EA 1Y2DA 3G4IA 4HF4A 3HQWA 1Y2JA 4YS7A 3K3EA 4LM0A 1XM6A 3I8VA 4QGEA 2OVVA 2OUNA 4LLKA 4DDLA 1XN0A 3SL5A 3QI4A 5AXPA 2H40A 5C2EA 1XM4A 4PHLA 4Y2BA 4HEUA 1ZKNA 4HTZA 3KKTA 4MRZA 4YQHA 3DYLA 5B4KA 3SNLA 5C2AA 5K1IA 3ECMA 1XM4B 4MSNA 4OEWA 4AJFA 4I9ZA 4AJMA 1UDUA 4TPMA 3WI2A 4LM3A 4XY2A 4G2JA 5K32A 2OURA 2QYNA 3G4LA 3HR1A 4FCBA 4MSAA 4G2WA 1XOTA 4NPWA 4D09A 2PW3A 4G2LA 5EDHA 3O0JA 4X0FA 4OGBA 3HC8A 3SL4A 3GWTA 5EDGA 4OEXA 1RO6A 1Y2EA 1XOQA 3UI7A 1XLZA 3HQZA 2OUUA 4NPVA 4LLPA 3TVXA 3V94A 3K4SA 1XMYA 3O57A 2CHMA 4WZIA 5EDGB 5AXQA 3SIEA 3ECNA 1RO9A 4AJGA
chains in the Genus database with same CATH topology
2QYMA 1RORA 1XMYB 4D08A 3WYKA 1F0JA 3DY8A 3D3PA 1Q9MA 1XOSA 4MSEA 4IA0A 3K3HA 5I2RA 3LY2A 4FCDA 1XP0A 3WS9A 1XMUA 3QPPA 3V93A 4LLJA 3TGEA 1Z1LA 3JWQA 3HDZA 4LM2A 3B2RA 3QPOA 1MKDA 4MD6A 4ZO5A 2OUPA 1XMUB 4PHWA 4Y8CA 3WYLA 4MVHA 4Y86A 5EDIA 2FM0A 2OVYA 2OUVA 4MRWA 3WS8A 5DH4A 4JIBA 1TBBA 4AELA 3G3NA 5EDEA 1PTWA 2QYLA 4KP6A 4PM0A 5EDIB 1XONA 2OUSA 1XORA 2Y0JA 4I15A 5C1WA 5K9RA 4LLXA 5EDEB 3UUOA 1UHOA 5C28A 4HTXA 3SL6A 3FRGA 4WCUA 4TPPA 4WN1A 3G45A 3V9BA 3DYSA 5DH5A 3SHYA 4Y87A 1T9RA 1TAZA 3QPNA 4GH6A 3IBJA 4W1OA 2HD1A 3WYMA 1XOMA 2WEYA 3SL8A 3SNIA 1SOJA 3IADA 3BJCA 1Y2HA 1OYNA 1Y2CA 2OUQA 3G4KA 3SL3A 3SN7A 1TB7A 1SO2A 4P0NA 2OUYA 4NW7A 4C1IA 1Y2KA 4MUWA 2YY2A 3JSIA 3N3ZA 3G58A 2FM5A 4LM4A 3DYQA 3WD9A 5C29A 4LKQA 4MS0A 2H42A 1RKPA 4DFFA 3O56A 4MYQA 3ITMA 3DYNA 3LXGA 3QI3A 4MSHA 3ITUA 1TBFA 4LM1A 2H44A 1XLXA 1T9SA 2R8QA 3JWRA 1Y2BA 4G2YA 3TGGA 3HMVA 4MSCA 1ZKLA 2QYKA 4P1RA 5B25A 1UDTA 3IAKA 3SHZA 5B4LA 1XOZA 4E90A 2O8HA 4BBXA 4AJDA 1TB5A 5C2HA 3G4GA 3HQYA 3JSWA 3W5EA 1Y2DA 3G4IA 4HF4A 3HQWA 1Y2JA 4YS7A 3K3EA 4LM0A 1XM6A 3I8VA 4QGEA 2OVVA 2OUNA 4LLKA 4DDLA 1XN0A 3SL5A 3QI4A 5AXPA 2H40A 5C2EA 1XM4A 4PHLA 4Y2BA 4HEUA 1ZKNA 4HTZA 3KKTA 4MRZA 4YQHA 3DYLA 5B4KA 3SNLA 5C2AA 5K1IA 3ECMA 1XM4B 4MSNA 4OEWA 4AJFA 4I9ZA 4AJMA 1UDUA 4TPMA 3WI2A 4LM3A 4XY2A 4G2JA 5K32A 2OURA 2QYNA 3G4LA 3HR1A 4FCBA 4MSAA 4G2WA 1XOTA 4NPWA 4D09A 2PW3A 4G2LA 5EDHA 3O0JA 4X0FA 4OGBA 3HC8A 3SL4A 3GWTA 5EDGA 4OEXA 1RO6A 1Y2EA 1XOQA 3UI7A 1XLZA 3HQZA 2OUUA 4NPVA 4LLPA 3TVXA 3V94A 3K4SA 1XMYA 3O57A 2CHMA 4WZIA 5EDGB 5AXQA 3SIEA 3ECNA 1RO9A 4AJGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QYM A;  1ROR A;  1XMY B;  4D08 A;  3WYK A;  1F0J A;  3DY8 A;  3D3P A;  1Q9M A;  1XOS A;  4MSE A;  4IA0 A;  3K3H A;  5I2R A;  3LY2 A;  4FCD A;  1XP0 A;  3WS9 A;  1XMU A;  3QPP A;  3V93 A;  4LLJ A;  3TGE A;  1Z1L A;  3JWQ A;  3HDZ A;  4LM2 A;  3B2R A;  3QPO A;  1MKD A;  4MD6 A;  4ZO5 A;  2OUP A;  1XMU B;  4PHW A;  4Y8C A;  3WYL A;  4MVH A;  4Y86 A;  5EDI A;  2FM0 A;  2OVY A;  2OUV A;  4MRW A;  3WS8 A;  5DH4 A;  4JIB A;  1TBB A;  4AEL A;  3G3N A;  5EDE A;  1PTW A;  2QYL A;  4KP6 A;  4PM0 A;  5EDI B;  1XON A;  2OUS A;  1XOR A;  2Y0J A;  4I15 A;  5C1W A;  5K9R A;  4LLX A;  5EDE B;  3UUO A;  1UHO A;  5C28 A;  4HTX A;  3SL6 A;  3FRG A;  4WCU A;  4TPP A;  4WN1 A;  3G45 A;  3V9B A;  3DYS A;  5DH5 A;  3SHY A;  4Y87 A;  1T9R A;  1TAZ A;  3QPN A;  4GH6 A;  3IBJ A;  4W1O A;  2HD1 A;  3WYM A;  1XOM A;  2WEY A;  3SL8 A;  3SNI A;  1SOJ A;  3IAD A;  3BJC A;  1Y2H A;  1OYN A;  1Y2C A;  2OUQ A;  3G4K A;  3SL3 A;  3SN7 A;  1TB7 A;  1SO2 A;  4P0N A;  2OUY A;  4NW7 A;  4C1I A;  1Y2K A;  4MUW A;  2YY2 A;  3JSI A;  3N3Z A;  3G58 A;  2FM5 A;  4LM4 A;  3DYQ A;  3WD9 A;  5C29 A;  4LKQ A;  4MS0 A;  2H42 A;  1RKP A;  4DFF A;  3O56 A;  4MYQ A;  3ITM A;  3DYN A;  3LXG A;  3QI3 A;  4MSH A;  3ITU A;  1TBF A;  4LM1 A;  2H44 A;  1XLX A;  1T9S A;  2R8Q A;  3JWR A;  1Y2B A;  4G2Y A;  3TGG A;  3HMV A;  4MSC A;  1ZKL A;  2QYK A;  4P1R A;  5B25 A;  1UDT A;  3IAK A;  3SHZ A;  5B4L A;  1XOZ A;  4E90 A;  2O8H A;  4BBX A;  4AJD A;  1TB5 A;  5C2H A;  3G4G A;  3HQY A;  3JSW A;  3W5E A;  1Y2D A;  3G4I A;  4HF4 A;  3HQW A;  1Y2J A;  4YS7 A;  3K3E A;  4LM0 A;  1XM6 A;  3I8V A;  4QGE A;  2OVV A;  2OUN A;  4LLK A;  4DDL A;  1XN0 A;  3SL5 A;  3QI4 A;  5AXP A;  2H40 A;  5C2E A;  1XM4 A;  4PHL A;  4Y2B A;  4HEU A;  1ZKN A;  4HTZ A;  3KKT A;  4MRZ A;  4YQH A;  3DYL A;  5B4K A;  3SNL A;  5C2A A;  5K1I A;  3ECM A;  1XM4 B;  4MSN A;  4OEW A;  4AJF A;  4I9Z A;  4AJM A;  1UDU A;  4TPM A;  3WI2 A;  4LM3 A;  4XY2 A;  4G2J A;  5K32 A;  2OUR A;  2QYN A;  3G4L A;  3HR1 A;  4FCB A;  4MSA A;  4G2W A;  1XOT A;  4NPW A;  4D09 A;  2PW3 A;  4G2L A;  5EDH A;  3O0J A;  4X0F A;  4OGB A;  3HC8 A;  3SL4 A;  3GWT A;  5EDG A;  4OEX A;  1RO6 A;  1Y2E A;  1XOQ A;  3UI7 A;  1XLZ A;  3HQZ A;  2OUU A;  4NPV A;  4LLP A;  3TVX A;  3V94 A;  3K4S A;  1XMY A;  3O57 A;  2CHM A;  4WZI A;  5EDG B;  5AXQ A;  3SIE A;  3ECN A;  1RO9 A;  4AJG A; 
#chains in the Genus database with same CATH topology
 2QYM A;  1ROR A;  1XMY B;  4D08 A;  3WYK A;  1F0J A;  3DY8 A;  3D3P A;  1Q9M A;  1XOS A;  4MSE A;  4IA0 A;  3K3H A;  5I2R A;  3LY2 A;  4FCD A;  1XP0 A;  3WS9 A;  1XMU A;  3QPP A;  3V93 A;  4LLJ A;  3TGE A;  1Z1L A;  3JWQ A;  3HDZ A;  4LM2 A;  3B2R A;  3QPO A;  1MKD A;  4MD6 A;  4ZO5 A;  2OUP A;  1XMU B;  4PHW A;  4Y8C A;  3WYL A;  4MVH A;  4Y86 A;  5EDI A;  2FM0 A;  2OVY A;  2OUV A;  4MRW A;  3WS8 A;  5DH4 A;  4JIB A;  1TBB A;  4AEL A;  3G3N A;  5EDE A;  1PTW A;  2QYL A;  4KP6 A;  4PM0 A;  5EDI B;  1XON A;  2OUS A;  1XOR A;  2Y0J A;  4I15 A;  5C1W A;  5K9R A;  4LLX A;  5EDE B;  3UUO A;  1UHO A;  5C28 A;  4HTX A;  3SL6 A;  3FRG A;  4WCU A;  4TPP A;  4WN1 A;  3G45 A;  3V9B A;  3DYS A;  5DH5 A;  3SHY A;  4Y87 A;  1T9R A;  1TAZ A;  3QPN A;  4GH6 A;  3IBJ A;  4W1O A;  2HD1 A;  3WYM A;  1XOM A;  2WEY A;  3SL8 A;  3SNI A;  1SOJ A;  3IAD A;  3BJC A;  1Y2H A;  1OYN A;  1Y2C A;  2OUQ A;  3G4K A;  3SL3 A;  3SN7 A;  1TB7 A;  1SO2 A;  4P0N A;  2OUY A;  4NW7 A;  4C1I A;  1Y2K A;  4MUW A;  2YY2 A;  3JSI A;  3N3Z A;  3G58 A;  2FM5 A;  4LM4 A;  3DYQ A;  3WD9 A;  5C29 A;  4LKQ A;  4MS0 A;  2H42 A;  1RKP A;  4DFF A;  3O56 A;  4MYQ A;  3ITM A;  3DYN A;  3LXG A;  3QI3 A;  4MSH A;  3ITU A;  1TBF A;  4LM1 A;  2H44 A;  1XLX A;  1T9S A;  2R8Q A;  3JWR A;  1Y2B A;  4G2Y A;  3TGG A;  3HMV A;  4MSC A;  1ZKL A;  2QYK A;  4P1R A;  5B25 A;  1UDT A;  3IAK A;  3SHZ A;  5B4L A;  1XOZ A;  4E90 A;  2O8H A;  4BBX A;  4AJD A;  1TB5 A;  5C2H A;  3G4G A;  3HQY A;  3JSW A;  3W5E A;  1Y2D A;  3G4I A;  4HF4 A;  3HQW A;  1Y2J A;  4YS7 A;  3K3E A;  4LM0 A;  1XM6 A;  3I8V A;  4QGE A;  2OVV A;  2OUN A;  4LLK A;  4DDL A;  1XN0 A;  3SL5 A;  3QI4 A;  5AXP A;  2H40 A;  5C2E A;  1XM4 A;  4PHL A;  4Y2B A;  4HEU A;  1ZKN A;  4HTZ A;  3KKT A;  4MRZ A;  4YQH A;  3DYL A;  5B4K A;  3SNL A;  5C2A A;  5K1I A;  3ECM A;  1XM4 B;  4MSN A;  4OEW A;  4AJF A;  4I9Z A;  4AJM A;  1UDU A;  4TPM A;  3WI2 A;  4LM3 A;  4XY2 A;  4G2J A;  5K32 A;  2OUR A;  2QYN A;  3G4L A;  3HR1 A;  4FCB A;  4MSA A;  4G2W A;  1XOT A;  4NPW A;  4D09 A;  2PW3 A;  4G2L A;  5EDH A;  3O0J A;  4X0F A;  4OGB A;  3HC8 A;  3SL4 A;  3GWT A;  5EDG A;  4OEX A;  1RO6 A;  1Y2E A;  1XOQ A;  3UI7 A;  1XLZ A;  3HQZ A;  2OUU A;  4NPV A;  4LLP A;  3TVX A;  3V94 A;  3K4S A;  1XMY A;  3O57 A;  2CHM A;  4WZI A;  5EDG B;  5AXQ A;  3SIE A;  3ECN A;  1RO9 A;  4AJG A; 
#chains in the Genus database with same CATH homology
 2QYM A;  1ROR A;  1XMY B;  4D08 A;  3WYK A;  1F0J A;  3DY8 A;  3D3P A;  1Q9M A;  1XOS A;  4MSE A;  4IA0 A;  3K3H A;  5I2R A;  3LY2 A;  4FCD A;  1XP0 A;  3WS9 A;  1XMU A;  3QPP A;  3V93 A;  4LLJ A;  3TGE A;  1Z1L A;  3JWQ A;  3HDZ A;  4LM2 A;  3B2R A;  3QPO A;  1MKD A;  4MD6 A;  4ZO5 A;  2OUP A;  1XMU B;  4PHW A;  4Y8C A;  3WYL A;  4MVH A;  4Y86 A;  5EDI A;  2FM0 A;  2OVY A;  2OUV A;  4MRW A;  3WS8 A;  5DH4 A;  4JIB A;  1TBB A;  4AEL A;  3G3N A;  5EDE A;  1PTW A;  2QYL A;  4KP6 A;  4PM0 A;  5EDI B;  1XON A;  2OUS A;  1XOR A;  2Y0J A;  4I15 A;  5C1W A;  5K9R A;  4LLX A;  5EDE B;  3UUO A;  1UHO A;  5C28 A;  4HTX A;  3SL6 A;  3FRG A;  4WCU A;  4TPP A;  4WN1 A;  3G45 A;  3V9B A;  3DYS A;  5DH5 A;  3SHY A;  4Y87 A;  1T9R A;  1TAZ A;  3QPN A;  4GH6 A;  3IBJ A;  4W1O A;  2HD1 A;  3WYM A;  1XOM A;  2WEY A;  3SL8 A;  3SNI A;  1SOJ A;  3IAD A;  3BJC A;  1Y2H A;  1OYN A;  1Y2C A;  2OUQ A;  3G4K A;  3SL3 A;  3SN7 A;  1TB7 A;  1SO2 A;  4P0N A;  2OUY A;  4NW7 A;  4C1I A;  1Y2K A;  4MUW A;  2YY2 A;  3JSI A;  3N3Z A;  3G58 A;  2FM5 A;  4LM4 A;  3DYQ A;  3WD9 A;  5C29 A;  4LKQ A;  4MS0 A;  2H42 A;  1RKP A;  4DFF A;  3O56 A;  4MYQ A;  3ITM A;  3DYN A;  3LXG A;  3QI3 A;  4MSH A;  3ITU A;  1TBF A;  4LM1 A;  2H44 A;  1XLX A;  1T9S A;  2R8Q A;  3JWR A;  1Y2B A;  4G2Y A;  3TGG A;  3HMV A;  4MSC A;  1ZKL A;  2QYK A;  4P1R A;  5B25 A;  1UDT A;  3IAK A;  3SHZ A;  5B4L A;  1XOZ A;  4E90 A;  2O8H A;  4BBX A;  4AJD A;  1TB5 A;  5C2H A;  3G4G A;  3HQY A;  3JSW A;  3W5E A;  1Y2D A;  3G4I A;  4HF4 A;  3HQW A;  1Y2J A;  4YS7 A;  3K3E A;  4LM0 A;  1XM6 A;  3I8V A;  4QGE A;  2OVV A;  2OUN A;  4LLK A;  4DDL A;  1XN0 A;  3SL5 A;  3QI4 A;  5AXP A;  2H40 A;  5C2E A;  1XM4 A;  4PHL A;  4Y2B A;  4HEU A;  1ZKN A;  4HTZ A;  3KKT A;  4MRZ A;  4YQH A;  3DYL A;  5B4K A;  3SNL A;  5C2A A;  5K1I A;  3ECM A;  1XM4 B;  4MSN A;  4OEW A;  4AJF A;  4I9Z A;  4AJM A;  1UDU A;  4TPM A;  3WI2 A;  4LM3 A;  4XY2 A;  4G2J A;  5K32 A;  2OUR A;  2QYN A;  3G4L A;  3HR1 A;  4FCB A;  4MSA A;  4G2W A;  1XOT A;  4NPW A;  4D09 A;  2PW3 A;  4G2L A;  5EDH A;  3O0J A;  4X0F A;  4OGB A;  3HC8 A;  3SL4 A;  3GWT A;  5EDG A;  4OEX A;  1RO6 A;  1Y2E A;  1XOQ A;  3UI7 A;  1XLZ A;  3HQZ A;  2OUU A;  4NPV A;  4LLP A;  3TVX A;  3V94 A;  3K4S A;  1XMY A;  3O57 A;  2CHM A;  4WZI A;  5EDG B;  5AXQ A;  3SIE A;  3ECN A;  1RO9 A;  4AJG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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