4FGYB

Identification of a unique ppar ligand with an unexpected binding mode and antibetic activity
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
11
structure length
11
Chain Sequence
RHKILHRLLQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor Gamma (PPAR-gamma) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes.
pubmed doi rcsb
molecule tags Transcription/transferase/antibiotic
source organism Homo sapiens
molecule keywords Peroxisome proliferator-activated receptor gamma
total genus 1
structure length 11
sequence length 11
ec nomenclature ec 2.3.1.48: Histone acetyltransferase.
pdb deposition date 2012-06-05
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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