4GCYA

Structure of mycobacterium tuberculosis dutpase h21w mutant
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
163
structure length
163
Chain Sequence
SGLVPRGSHMSTTLAIVRLDPGLPLPSRAWDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEAGLASTSRGDGGHGSSGGHASL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title RAMD identification of substrate binding pathways to the active site of dUTPase
rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 24
structure length 163
sequence length 163
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2012-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 4gcyA01
3LOJA 2HQUA 2WE3A 3P48A 3TPWA 1SYLA 1PKHA 3TPSA 3C3IA 3C2TA 1PKJA 4DHKA 2XY3A 2WE1A 2HXBA 3ARAA 2Y1TA 5CCTA 1F7RA 4AOOA 2BT1A 2HRMA 4A6AA 3F4FA 3TQ3A 2PC5A 3ZF1A 2HXDA 4WRKA 3ZF6A 5ECTA 5F9KA 1MQ7A 3ZF4A 2YZJA 4APZ1 3TTAA 2OKBA 3T64A 2OKEA 2OL0A 3ZEZA 2BSYA 1DUCA 1F7PA 3T70A 3MBQA 1DUNA 1F7QA 3ARNA 2OL1A 1SEHA 1SMCA 3TRNA 2J4QA 2J4HA 3CA9A 3EHWA 2XX6A 5EDDA 3HHQA 3ZF5A 2XCDA 1XS4A 3H6XA 3HZAA 3T60A 2HR6A 2V9XA 3TQ5A 2D4NA 4AO5A 3KM3A 3TPYA 4B0HA 1SLHA 3MDXA 1SM8A 2BAZA 3ZF2A 1SNFA 4LHRA 3TPNA 1VYQA 1XS6A 3TQ4A 3I93A 3TS6A 1DUTA 2ZDCA 4GK6A 3TP1A 3ZF3A 1EUWA 1F7NA 4GCYA 2R9QA 4AOZA 2OKDA 1F7OA 3TRLA 1F7DA 3LQWA 1Q5HA 1EU5A 1F7KA 4OOQA 3ZF0A 2WE0A 3GF0A 3TQZA 1PKKA 2XCEA 1RN8A 2QLPA 3H6DA 3SO2A 3T6YA 2Y8CA 3ECYA 1RNJA 2QXXA 4XJCA 1SIXA 1Q5UX 5CCOA 1SJNA 1OGHA 2PY4A 3TSLA 2D4LA 2WE2A 1DUDA 4GV8A 2D4MA 1DUPA 1XS1A 4OOPA
chains in the Genus database with same CATH superfamily
3LOJA 2HQUA 2WE3A 3P48A 3TPWA 1SYLA 1PKHA 3TPSA 3C3IA 3C2TA 1PKJA 4DHKA 1TULA 2XY3A 2WE1A 2HXBA 3ARAA 2Y1TA 5CCTA 1F7RA 4AOOA 2BT1A 2HRMA 4A6AA 3F4FA 3TQ3A 2PC5A 3ZF1A 2HXDA 4WRKA 3ZF6A 5ECTA 5F9KA 1MQ7A 3ZF4A 2YZJA 4APZ1 3TTAA 2OKBA 3T64A 2OKEA 2OL0A 3ZEZA 2BSYA 1DUCA 1F7PA 3T70A 3MBQA 1DUNA 1F7QA 3ARNA 2OL1A 1SEHA 1SMCA 3TRNA 2J4QA 2J4HA 3CA9A 3EHWA 2XX6A 5EDDA 3HHQA 3ZF5A 2XCDA 1XS4A 3H6XA 3HZAA 3T60A 2HR6A 2V9XA 3TQ5A 2D4NA 4AO5A 3KM3A 3TPYA 4B0HA 1SLHA 3MDXA 1SM8A 2BAZA 3ZF2A 1SNFA 4LHRA 3TPNA 1VYQA 1XS6A 3TQ4A 3I93A 3TS6A 1DUTA 2ZDCA 4GK6A 3TP1A 3ZF3A 1EUWA 1F7NA 4GCYA 2R9QA 4AOZA 2OKDA 1F7OA 3TRLA 1F7DA 3LQWA 1Q5HA 1EU5A 1F7KA 4OOQA 3ZF0A 2WE0A 3GF0A 3TQZA 1PKKA 2XCEA 1RN8A 2QLPA 3H6DA 3SO2A 3T6YA 2Y8CA 3ECYA 1RNJA 2QXXA 4XJCA 1SIXA 1Q5UX 5CCOA 1SJNA 1OGHA 2PY4A 3TSLA 2D4LA 2WE2A 1DUDA 4GV8A 2D4MA 1DUPA 1XS1A 4OOPA
chains in the Genus database with same CATH topology
3LOJA 2HQUA 2WE3A 3P48A 3TPWA 1SYLA 1PKHA 3TPSA 3C3IA 3C2TA 1PKJA 4DHKA 2XY3A 2WE1A 2HXBA 3ARAA 2Y1TA 5CCTA 1F7RA 4AOOA 2BT1A 2HRMA 4A6AA 3F4FA 3TQ3A 2PC5A 3ZF1A 2HXDA 4WRKA 3ZF6A 5ECTA 5F9KA 1MQ7A 3ZF4A 2YZJA 4APZ1 3TTAA 2OKBA 3T64A 2OKEA 2OL0A 3ZEZA 2BSYA 1DUCA 1F7PA 3T70A 3MBQA 1DUNA 1F7QA 3ARNA 2OL1A 1SEHA 1SMCA 3TRNA 2J4QA 2J4HA 3CA9A 3EHWA 2XX6A 5EDDA 3HHQA 3ZF5A 2XCDA 1XS4A 3H6XA 3HZAA 3T60A 2HR6A 2V9XA 3TQ5A 2D4NA 4AO5A 3KM3A 3TPYA 4B0HA 1SLHA 3MDXA 1SM8A 2BAZA 3ZF2A 1SNFA 4LHRA 3TPNA 1VYQA 1XS6A 3TQ4A 3I93A 3TS6A 1DUTA 2ZDCA 4GK6A 3TP1A 3ZF3A 1EUWA 1F7NA 4GCYA 2R9QA 4AOZA 2OKDA 1F7OA 3TRLA 1F7DA 3LQWA 1Q5HA 1EU5A 1F7KA 4OOQA 3ZF0A 2WE0A 3GF0A 3TQZA 1PKKA 2XCEA 1RN8A 2QLPA 3H6DA 3SO2A 3T6YA 2Y8CA 3ECYA 1RNJA 2QXXA 4XJCA 1SIXA 1Q5UX 5CCOA 1SJNA 1OGHA 2PY4A 3TSLA 2D4LA 2WE2A 1DUDA 4GV8A 2D4MA 1DUPA 1XS1A 4OOPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LOJ A;  2HQU A;  2WE3 A;  3P48 A;  3TPW A;  1SYL A;  1PKH A;  3TPS A;  3C3I A;  3C2T A;  1PKJ A;  4DHK A;  2XY3 A;  2WE1 A;  2HXB A;  3ARA A;  2Y1T A;  5CCT A;  1F7R A;  4AOO A;  2BT1 A;  2HRM A;  4A6A A;  3F4F A;  3TQ3 A;  2PC5 A;  3ZF1 A;  2HXD A;  4WRK A;  3ZF6 A;  5ECT A;  5F9K A;  1MQ7 A;  3ZF4 A;  2YZJ A;  4APZ 1;  3TTA A;  2OKB A;  3T64 A;  2OKE A;  2OL0 A;  3ZEZ A;  2BSY A;  1DUC A;  1F7P A;  3T70 A;  3MBQ A;  1DUN A;  1F7Q A;  3ARN A;  2OL1 A;  1SEH A;  1SMC A;  3TRN A;  2J4Q A;  2J4H A;  3CA9 A;  3EHW A;  2XX6 A;  5EDD A;  3HHQ A;  3ZF5 A;  2XCD A;  1XS4 A;  3H6X A;  3HZA A;  3T60 A;  2HR6 A;  2V9X A;  3TQ5 A;  2D4N A;  4AO5 A;  3KM3 A;  3TPY A;  4B0H A;  1SLH A;  3MDX A;  1SM8 A;  2BAZ A;  3ZF2 A;  1SNF A;  4LHR A;  3TPN A;  1VYQ A;  1XS6 A;  3TQ4 A;  3I93 A;  3TS6 A;  1DUT A;  2ZDC A;  4GK6 A;  3TP1 A;  3ZF3 A;  1EUW A;  1F7N A;  4GCY A;  2R9Q A;  4AOZ A;  2OKD A;  1F7O A;  3TRL A;  1F7D A;  3LQW A;  1Q5H A;  1EU5 A;  1F7K A;  4OOQ A;  3ZF0 A;  2WE0 A;  3GF0 A;  3TQZ A;  1PKK A;  2XCE A;  1RN8 A;  2QLP A;  3H6D A;  3SO2 A;  3T6Y A;  2Y8C A;  3ECY A;  1RNJ A;  2QXX A;  4XJC A;  1SIX A;  1Q5U X;  5CCO A;  1SJN A;  1OGH A;  2PY4 A;  3TSL A;  2D4L A;  2WE2 A;  1DUD A;  4GV8 A;  2D4M A;  1DUP A;  1XS1 A;  4OOP A; 
#chains in the Genus database with same CATH topology
 3LOJ A;  2HQU A;  2WE3 A;  3P48 A;  3TPW A;  1SYL A;  1PKH A;  3TPS A;  3C3I A;  3C2T A;  1PKJ A;  4DHK A;  1TUL A;  2XY3 A;  2WE1 A;  2HXB A;  3ARA A;  2Y1T A;  5CCT A;  1F7R A;  4AOO A;  2BT1 A;  2HRM A;  4A6A A;  3F4F A;  3TQ3 A;  2PC5 A;  3ZF1 A;  2HXD A;  4WRK A;  3ZF6 A;  5ECT A;  5F9K A;  1MQ7 A;  3ZF4 A;  2YZJ A;  4APZ 1;  3TTA A;  2OKB A;  3T64 A;  2OKE A;  2OL0 A;  3ZEZ A;  2BSY A;  1DUC A;  1F7P A;  3T70 A;  3MBQ A;  1DUN A;  1F7Q A;  3ARN A;  2OL1 A;  1SEH A;  1SMC A;  3TRN A;  2J4Q A;  2J4H A;  3CA9 A;  3EHW A;  2XX6 A;  5EDD A;  3HHQ A;  3ZF5 A;  2XCD A;  1XS4 A;  3H6X A;  3HZA A;  3T60 A;  2HR6 A;  2V9X A;  3TQ5 A;  2D4N A;  4AO5 A;  3KM3 A;  3TPY A;  4B0H A;  1SLH A;  3MDX A;  1SM8 A;  2BAZ A;  3ZF2 A;  1SNF A;  4LHR A;  3TPN A;  1VYQ A;  1XS6 A;  3TQ4 A;  3I93 A;  3TS6 A;  1DUT A;  2ZDC A;  4GK6 A;  3TP1 A;  3ZF3 A;  1EUW A;  1F7N A;  4GCY A;  2R9Q A;  4AOZ A;  2OKD A;  1F7O A;  3TRL A;  1F7D A;  3LQW A;  1Q5H A;  1EU5 A;  1F7K A;  4OOQ A;  3ZF0 A;  2WE0 A;  3GF0 A;  3TQZ A;  1PKK A;  2XCE A;  1RN8 A;  2QLP A;  3H6D A;  3SO2 A;  3T6Y A;  2Y8C A;  3ECY A;  1RNJ A;  2QXX A;  4XJC A;  1SIX A;  1Q5U X;  5CCO A;  1SJN A;  1OGH A;  2PY4 A;  3TSL A;  2D4L A;  2WE2 A;  1DUD A;  4GV8 A;  2D4M A;  1DUP A;  1XS1 A;  4OOP A; 
#chains in the Genus database with same CATH homology
 3LOJ A;  2HQU A;  2WE3 A;  3P48 A;  3TPW A;  1SYL A;  1PKH A;  3TPS A;  3C3I A;  3C2T A;  1PKJ A;  4DHK A;  2XY3 A;  2WE1 A;  2HXB A;  3ARA A;  2Y1T A;  5CCT A;  1F7R A;  4AOO A;  2BT1 A;  2HRM A;  4A6A A;  3F4F A;  3TQ3 A;  2PC5 A;  3ZF1 A;  2HXD A;  4WRK A;  3ZF6 A;  5ECT A;  5F9K A;  1MQ7 A;  3ZF4 A;  2YZJ A;  4APZ 1;  3TTA A;  2OKB A;  3T64 A;  2OKE A;  2OL0 A;  3ZEZ A;  2BSY A;  1DUC A;  1F7P A;  3T70 A;  3MBQ A;  1DUN A;  1F7Q A;  3ARN A;  2OL1 A;  1SEH A;  1SMC A;  3TRN A;  2J4Q A;  2J4H A;  3CA9 A;  3EHW A;  2XX6 A;  5EDD A;  3HHQ A;  3ZF5 A;  2XCD A;  1XS4 A;  3H6X A;  3HZA A;  3T60 A;  2HR6 A;  2V9X A;  3TQ5 A;  2D4N A;  4AO5 A;  3KM3 A;  3TPY A;  4B0H A;  1SLH A;  3MDX A;  1SM8 A;  2BAZ A;  3ZF2 A;  1SNF A;  4LHR A;  3TPN A;  1VYQ A;  1XS6 A;  3TQ4 A;  3I93 A;  3TS6 A;  1DUT A;  2ZDC A;  4GK6 A;  3TP1 A;  3ZF3 A;  1EUW A;  1F7N A;  4GCY A;  2R9Q A;  4AOZ A;  2OKD A;  1F7O A;  3TRL A;  1F7D A;  3LQW A;  1Q5H A;  1EU5 A;  1F7K A;  4OOQ A;  3ZF0 A;  2WE0 A;  3GF0 A;  3TQZ A;  1PKK A;  2XCE A;  1RN8 A;  2QLP A;  3H6D A;  3SO2 A;  3T6Y A;  2Y8C A;  3ECY A;  1RNJ A;  2QXX A;  4XJC A;  1SIX A;  1Q5U X;  5CCO A;  1SJN A;  1OGH A;  2PY4 A;  3TSL A;  2D4L A;  2WE2 A;  1DUD A;  4GV8 A;  2D4M A;  1DUP A;  1XS1 A;  4OOP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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