4GK6A

X-ray crystal structure of a hypothetical deoxyuridine 5-triphosphate nucleotidohydrolase from mycobacterium abscessus
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
136
structure length
136
Chain Sequence
GSMLAIVRLDRELPLPSRAHADDAGVDLYSAEDVVIEPGRRTLVGTGIAVAIPSGMVGLVHPRSGLAARVGLSIVNSPGTIDAGYRGEVKVNLINLDSEVPIVIARGDRIAQLLVQQVELPELVEVDSFDEAGLAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium abscessus
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 15
structure length 136
sequence length 136
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2012-08-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 4gk6A00
3TP1A 3ZF3A 1SM8A 3ZF2A 1SYLA 3LOJA 1F7NA 3CA9A 2OKBA 3TQ3A 1SLHA 3TRLA 4DHKA 1F7QA 3C3IA 1OGHA 4A6AA 1RN8A 3ZF1A 3TPYA 2XCEA 2BAZA 3GF0A 2D4MA 1SJNA 1VYQA 2QLPA 3ZEZA 3ZF4A 2BT1A 2WE3A 2WE0A 1F7OA 3SO2A 1F7PA 4OOPA 4AO5A 2D4LA 2WE1A 3ECYA 5CCOA 1XS6A 4GK6A 1MQ7A 2Y8CA 3TPSA 3HHQA 3TPNA 3T60A 2J4HA 2Y1TA 2PC5A 1PKJA 1PKHA 3P48A 2OL0A 1SMCA 1F7RA 2XY3A 2OL1A 3T6YA 3HZAA 1Q5HA 2BSYA 1Q5UX 3TS6A 3TSLA 1SIXA 4GCYA 2HXBA 4AOZA 1EU5A 2R9QA 2V9XA 5EDDA 3I93A 2XX6A 5ECTA 1PKKA 2HRMA 2QXXA 3F4FA 5CCTA 1SEHA 3LQWA 3TQ4A 1RNJA 4AOOA 3EHWA 2HQUA 2D4NA 3C2TA 4LHRA 2YZJA 3H6DA 2OKDA 2OKEA 2ZDCA 1SNFA 3ZF6A 3T64A 3H6XA 1DUPA 2PY4A 4B0HA 3KM3A 5F9KA 3ARNA 1DUTA 1DUDA 4APZ1 1F7KA 3TPWA 1EUWA 3TQ5A 1F7DA 2XCDA 3ARAA 2WE2A 3MBQA 1DUCA 4GV8A 2HXDA 2J4QA 1XS4A 2HR6A 3TTAA 3ZF0A 3MDXA 3TQZA 4WRKA 3T70A 1DUNA 1XS1A 4OOQA 3TRNA 3ZF5A 4XJCA
chains in the Genus database with same CATH superfamily
3TP1A 3ZF3A 1SM8A 3ZF2A 1SYLA 3LOJA 1F7NA 3CA9A 2OKBA 3TQ3A 1SLHA 3TRLA 4DHKA 1F7QA 3C3IA 1OGHA 4A6AA 1RN8A 3ZF1A 3TPYA 2XCEA 2BAZA 3GF0A 2D4MA 1SJNA 1VYQA 2QLPA 3ZEZA 3ZF4A 2BT1A 2WE3A 2WE0A 1F7OA 3SO2A 1F7PA 4OOPA 4AO5A 2D4LA 2WE1A 3ECYA 5CCOA 1XS6A 4GK6A 1MQ7A 2Y8CA 3TPSA 3HHQA 3TPNA 3T60A 2J4HA 2Y1TA 2PC5A 1PKJA 1PKHA 3P48A 2OL0A 1SMCA 1F7RA 2XY3A 2OL1A 3T6YA 3HZAA 1Q5HA 2BSYA 1Q5UX 3TS6A 3TSLA 1TULA 1SIXA 4GCYA 2HXBA 4AOZA 1EU5A 2R9QA 2V9XA 5EDDA 3I93A 2XX6A 5ECTA 1PKKA 2HRMA 2QXXA 3F4FA 5CCTA 1SEHA 3LQWA 3TQ4A 1RNJA 4AOOA 3EHWA 2HQUA 2D4NA 3C2TA 4LHRA 2YZJA 3H6DA 2OKDA 2OKEA 2ZDCA 1SNFA 3ZF6A 3T64A 3H6XA 1DUPA 2PY4A 4B0HA 3KM3A 5F9KA 3ARNA 1DUTA 1DUDA 4APZ1 1F7KA 3TPWA 1EUWA 3TQ5A 1F7DA 2XCDA 3ARAA 2WE2A 3MBQA 1DUCA 4GV8A 2HXDA 2J4QA 1XS4A 2HR6A 3TTAA 3ZF0A 3MDXA 3TQZA 4WRKA 3T70A 1DUNA 1XS1A 4OOQA 3TRNA 3ZF5A 4XJCA
chains in the Genus database with same CATH topology
3TP1A 3ZF3A 1SM8A 3ZF2A 1SYLA 3LOJA 1F7NA 3CA9A 2OKBA 3TQ3A 1SLHA 3TRLA 4DHKA 1F7QA 3C3IA 1OGHA 4A6AA 1RN8A 3ZF1A 3TPYA 2XCEA 2BAZA 3GF0A 2D4MA 1SJNA 1VYQA 2QLPA 3ZEZA 3ZF4A 2BT1A 2WE3A 2WE0A 1F7OA 3SO2A 1F7PA 4OOPA 4AO5A 2D4LA 2WE1A 3ECYA 5CCOA 1XS6A 4GK6A 1MQ7A 2Y8CA 3TPSA 3HHQA 3TPNA 3T60A 2J4HA 2Y1TA 2PC5A 1PKJA 1PKHA 3P48A 2OL0A 1SMCA 1F7RA 2XY3A 2OL1A 3T6YA 3HZAA 1Q5HA 2BSYA 1Q5UX 3TS6A 3TSLA 1SIXA 4GCYA 2HXBA 4AOZA 1EU5A 2R9QA 2V9XA 5EDDA 3I93A 2XX6A 5ECTA 1PKKA 2HRMA 2QXXA 3F4FA 5CCTA 1SEHA 3LQWA 3TQ4A 1RNJA 4AOOA 3EHWA 2HQUA 2D4NA 3C2TA 4LHRA 2YZJA 3H6DA 2OKDA 2OKEA 2ZDCA 1SNFA 3ZF6A 3T64A 3H6XA 1DUPA 2PY4A 4B0HA 3KM3A 5F9KA 3ARNA 1DUTA 1DUDA 4APZ1 1F7KA 3TPWA 1EUWA 3TQ5A 1F7DA 2XCDA 3ARAA 2WE2A 3MBQA 1DUCA 4GV8A 2HXDA 2J4QA 1XS4A 2HR6A 3TTAA 3ZF0A 3MDXA 3TQZA 4WRKA 3T70A 1DUNA 1XS1A 4OOQA 3TRNA 3ZF5A 4XJCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TP1 A;  3ZF3 A;  1SM8 A;  3ZF2 A;  1SYL A;  3LOJ A;  1F7N A;  3CA9 A;  2OKB A;  3TQ3 A;  1SLH A;  3TRL A;  4DHK A;  1F7Q A;  3C3I A;  1OGH A;  4A6A A;  1RN8 A;  3ZF1 A;  3TPY A;  2XCE A;  2BAZ A;  3GF0 A;  2D4M A;  1SJN A;  1VYQ A;  2QLP A;  3ZEZ A;  3ZF4 A;  2BT1 A;  2WE3 A;  2WE0 A;  1F7O A;  3SO2 A;  1F7P A;  4OOP A;  4AO5 A;  2D4L A;  2WE1 A;  3ECY A;  5CCO A;  1XS6 A;  4GK6 A;  1MQ7 A;  2Y8C A;  3TPS A;  3HHQ A;  3TPN A;  3T60 A;  2J4H A;  2Y1T A;  2PC5 A;  1PKJ A;  1PKH A;  3P48 A;  2OL0 A;  1SMC A;  1F7R A;  2XY3 A;  2OL1 A;  3T6Y A;  3HZA A;  1Q5H A;  2BSY A;  1Q5U X;  3TS6 A;  3TSL A;  1SIX A;  4GCY A;  2HXB A;  4AOZ A;  1EU5 A;  2R9Q A;  2V9X A;  5EDD A;  3I93 A;  2XX6 A;  5ECT A;  1PKK A;  2HRM A;  2QXX A;  3F4F A;  5CCT A;  1SEH A;  3LQW A;  3TQ4 A;  1RNJ A;  4AOO A;  3EHW A;  2HQU A;  2D4N A;  3C2T A;  4LHR A;  2YZJ A;  3H6D A;  2OKD A;  2OKE A;  2ZDC A;  1SNF A;  3ZF6 A;  3T64 A;  3H6X A;  1DUP A;  2PY4 A;  4B0H A;  3KM3 A;  5F9K A;  3ARN A;  1DUT A;  1DUD A;  4APZ 1;  1F7K A;  3TPW A;  1EUW A;  3TQ5 A;  1F7D A;  2XCD A;  3ARA A;  2WE2 A;  3MBQ A;  1DUC A;  4GV8 A;  2HXD A;  2J4Q A;  1XS4 A;  2HR6 A;  3TTA A;  3ZF0 A;  3MDX A;  3TQZ A;  4WRK A;  3T70 A;  1DUN A;  1XS1 A;  4OOQ A;  3TRN A;  3ZF5 A;  4XJC A; 
#chains in the Genus database with same CATH topology
 3TP1 A;  3ZF3 A;  1SM8 A;  3ZF2 A;  1SYL A;  3LOJ A;  1F7N A;  3CA9 A;  2OKB A;  3TQ3 A;  1SLH A;  3TRL A;  4DHK A;  1F7Q A;  3C3I A;  1OGH A;  4A6A A;  1RN8 A;  3ZF1 A;  3TPY A;  2XCE A;  2BAZ A;  3GF0 A;  2D4M A;  1SJN A;  1VYQ A;  2QLP A;  3ZEZ A;  3ZF4 A;  2BT1 A;  2WE3 A;  2WE0 A;  1F7O A;  3SO2 A;  1F7P A;  4OOP A;  4AO5 A;  2D4L A;  2WE1 A;  3ECY A;  5CCO A;  1XS6 A;  4GK6 A;  1MQ7 A;  2Y8C A;  3TPS A;  3HHQ A;  3TPN A;  3T60 A;  2J4H A;  2Y1T A;  2PC5 A;  1PKJ A;  1PKH A;  3P48 A;  2OL0 A;  1SMC A;  1F7R A;  2XY3 A;  2OL1 A;  3T6Y A;  3HZA A;  1Q5H A;  2BSY A;  1Q5U X;  3TS6 A;  3TSL A;  1TUL A;  1SIX A;  4GCY A;  2HXB A;  4AOZ A;  1EU5 A;  2R9Q A;  2V9X A;  5EDD A;  3I93 A;  2XX6 A;  5ECT A;  1PKK A;  2HRM A;  2QXX A;  3F4F A;  5CCT A;  1SEH A;  3LQW A;  3TQ4 A;  1RNJ A;  4AOO A;  3EHW A;  2HQU A;  2D4N A;  3C2T A;  4LHR A;  2YZJ A;  3H6D A;  2OKD A;  2OKE A;  2ZDC A;  1SNF A;  3ZF6 A;  3T64 A;  3H6X A;  1DUP A;  2PY4 A;  4B0H A;  3KM3 A;  5F9K A;  3ARN A;  1DUT A;  1DUD A;  4APZ 1;  1F7K A;  3TPW A;  1EUW A;  3TQ5 A;  1F7D A;  2XCD A;  3ARA A;  2WE2 A;  3MBQ A;  1DUC A;  4GV8 A;  2HXD A;  2J4Q A;  1XS4 A;  2HR6 A;  3TTA A;  3ZF0 A;  3MDX A;  3TQZ A;  4WRK A;  3T70 A;  1DUN A;  1XS1 A;  4OOQ A;  3TRN A;  3ZF5 A;  4XJC A; 
#chains in the Genus database with same CATH homology
 3TP1 A;  3ZF3 A;  1SM8 A;  3ZF2 A;  1SYL A;  3LOJ A;  1F7N A;  3CA9 A;  2OKB A;  3TQ3 A;  1SLH A;  3TRL A;  4DHK A;  1F7Q A;  3C3I A;  1OGH A;  4A6A A;  1RN8 A;  3ZF1 A;  3TPY A;  2XCE A;  2BAZ A;  3GF0 A;  2D4M A;  1SJN A;  1VYQ A;  2QLP A;  3ZEZ A;  3ZF4 A;  2BT1 A;  2WE3 A;  2WE0 A;  1F7O A;  3SO2 A;  1F7P A;  4OOP A;  4AO5 A;  2D4L A;  2WE1 A;  3ECY A;  5CCO A;  1XS6 A;  4GK6 A;  1MQ7 A;  2Y8C A;  3TPS A;  3HHQ A;  3TPN A;  3T60 A;  2J4H A;  2Y1T A;  2PC5 A;  1PKJ A;  1PKH A;  3P48 A;  2OL0 A;  1SMC A;  1F7R A;  2XY3 A;  2OL1 A;  3T6Y A;  3HZA A;  1Q5H A;  2BSY A;  1Q5U X;  3TS6 A;  3TSL A;  1SIX A;  4GCY A;  2HXB A;  4AOZ A;  1EU5 A;  2R9Q A;  2V9X A;  5EDD A;  3I93 A;  2XX6 A;  5ECT A;  1PKK A;  2HRM A;  2QXX A;  3F4F A;  5CCT A;  1SEH A;  3LQW A;  3TQ4 A;  1RNJ A;  4AOO A;  3EHW A;  2HQU A;  2D4N A;  3C2T A;  4LHR A;  2YZJ A;  3H6D A;  2OKD A;  2OKE A;  2ZDC A;  1SNF A;  3ZF6 A;  3T64 A;  3H6X A;  1DUP A;  2PY4 A;  4B0H A;  3KM3 A;  5F9K A;  3ARN A;  1DUT A;  1DUD A;  4APZ 1;  1F7K A;  3TPW A;  1EUW A;  3TQ5 A;  1F7D A;  2XCD A;  3ARA A;  2WE2 A;  3MBQ A;  1DUC A;  4GV8 A;  2HXD A;  2J4Q A;  1XS4 A;  2HR6 A;  3TTA A;  3ZF0 A;  3MDX A;  3TQZ A;  4WRK A;  3T70 A;  1DUN A;  1XS1 A;  4OOQ A;  3TRN A;  3ZF5 A;  4XJC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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