4MSNA

Crystal structure of pde10a2 with fragment zt0451 (8-nitroquinoline)
Total Genus 134
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
134
sequence length
330
structure length
330
Chain Sequence
AGTSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase
total genus 134
structure length 330
sequence length 330
chains with identical sequence B
ec nomenclature ec 3.1.4.17: 3',5'-cyclic-nucleotide phosphodiesterase.
pdb deposition date 2013-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00233 PDEase_I 3'5'-cyclic nucleotide phosphodiesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1300.10 Mainly Alpha Orthogonal Bundle Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 4msnA00
1Y2CA 2OUYA 3LXGA 4Y86A 5EDEB 4AJDA 4HTXA 2OUQA 5I2RA 1RORA 2FM0A 1SO2A 4FCBA 4E90A 1TB7A 4P0NA 3HQYA 3V93A 3DYQA 4GH6A 2PW3A 2QYNA 4Y8CA 3I8VA 3KKTA 2OUNA 4MSHA 4TPMA 1XOMA 5EDGB 5EDIB 2OUUA 2H40A 4D08A 1PTWA 3FRGA 3G4GA 3HQZA 2OUVA 1XOSA 4MYQA 4C1IA 3SHYA 1UHOA 3DYSA 3JSIA 3HQWA 1XM6A 3IAKA 1XMYA 3QPNA 2WEYA 2OUPA 1Y2EA 4MSNA 2OVYA 2Y0JA 4IA0A 4NPWA 1ZKNA 2FM5A 3LY2A 1UDTA 1XMUB 2OURA 4DFFA 3SL4A 1Z1LA 2R8QA 3K3HA 4WN1A 5C2HA 3O56A 4I15A 3SNLA 4TPPA 4BBXA 1XLZA 3GWTA 3ITUA 3JSWA 4Y2BA 4NPVA 4AJFA 4LLXA 1Y2JA 4KP6A 5DH5A 4ZO5A 3WS9A 4LLPA 1F0JA 1TBBA 5AXPA 1Y2DA 1XM4B 1XOZA 3DYLA 3ECMA 3HMVA 3WS8A 3O0JA 5AXQA 5EDEA 1Y2BA 2HD1A 4MS0A 4PHWA 5K9RA 4WCUA 3G45A 1TAZA 4DDLA 1RO9A 1T9SA 3UUOA 4AELA 3SNIA 3WD9A 5C29A 4AJGA 4AJMA 3TGEA 3SIEA 4LKQA 4LM3A 2QYKA 3TVXA 4OGBA 2YY2A 4HEUA 3SHZA 5EDIA 4MSCA 5EDGA 4LM2A 3SL5A 4YS7A 4QGEA 3TGGA 1SOJA 3SL3A 3HR1A 3SN7A 4LM0A 4PM0A 2QYMA 5K32A 4MVHA 3QI3A 3V94A 5C28A 4MSEA 1OYNA 4MRZA 3BJCA 3HDZA 3SL6A 3QI4A 1Y2HA 2H44A 4HTZA 4HF4A 4FCDA 3JWQA 3K3EA 4G2LA 1XN0A 3ECNA 3DYNA 3K4SA 3SL8A 4G2YA 3QPPA 5B4KA 1RO6A 1UDUA 5B4LA 1XONA 4MRWA 3G4IA 3G4KA 4P1RA 3HC8A 1T9RA 1XP0A 1Y2KA 2OUSA 3B2RA 1XMUA 3G58A 3IADA 3ITMA 5C2EA 1ZKLA 1TBFA 3W5EA 3IBJA 2O8HA 4MUWA 4LM4A 1XMYB 2H42A 4X0FA 3N3ZA 5B25A 3D3PA 3WYMA 4XY2A 2CHMA 4I9ZA 4G2WA 4NW7A 3O57A 3WYLA 3V9BA 4JIBA 3DY8A 4LLJA 4D09A 1Q9MA 1XM4A 4OEXA 4WZIA 5EDHA 5C1WA 5K1IA 3QPOA 1TB5A 2OVVA 4MD6A 3JWRA 3UI7A 3G4LA 4LLKA 5C2AA 4YQHA 4OEWA 4MSAA 4LM1A 1RKPA 3WYKA 1XLXA 5DH4A 4G2JA 3WI2A 3G3NA 1MKDA 1XOTA 4Y87A 1XORA 2QYLA 4PHLA 4W1OA 1XOQA
chains in the Genus database with same CATH superfamily
1Y2CA 2OUYA 3LXGA 4Y86A 5EDEB 4AJDA 4HTXA 2OUQA 5I2RA 1RORA 2FM0A 1SO2A 4FCBA 4E90A 1TB7A 4P0NA 3HQYA 3V93A 3DYQA 4GH6A 2PW3A 2QYNA 4Y8CA 3I8VA 3KKTA 2OUNA 4MSHA 4TPMA 1XOMA 5EDGB 5EDIB 2OUUA 2H40A 4D08A 1PTWA 3FRGA 3G4GA 3HQZA 2OUVA 1XOSA 4MYQA 4C1IA 3SHYA 1UHOA 3DYSA 3JSIA 3HQWA 1XM6A 3IAKA 1XMYA 3QPNA 2WEYA 2OUPA 1Y2EA 4MSNA 2OVYA 2Y0JA 4IA0A 4NPWA 1ZKNA 2FM5A 3LY2A 1UDTA 1XMUB 2OURA 4DFFA 3SL4A 1Z1LA 2R8QA 3K3HA 4WN1A 5C2HA 3O56A 4I15A 3SNLA 4TPPA 4BBXA 1XLZA 3GWTA 3ITUA 3JSWA 4Y2BA 4NPVA 4AJFA 4LLXA 1Y2JA 4KP6A 5DH5A 4ZO5A 3WS9A 4LLPA 1F0JA 1TBBA 5AXPA 1Y2DA 1XM4B 1XOZA 3DYLA 3ECMA 3HMVA 3WS8A 3O0JA 5AXQA 5EDEA 1Y2BA 2HD1A 4MS0A 4PHWA 5K9RA 4WCUA 3G45A 1TAZA 4DDLA 1RO9A 1T9SA 3UUOA 4AELA 3SNIA 3WD9A 5C29A 4AJGA 4AJMA 3TGEA 3SIEA 4LKQA 4LM3A 2QYKA 3TVXA 4OGBA 2YY2A 4HEUA 3SHZA 5EDIA 4MSCA 5EDGA 4LM2A 3SL5A 4YS7A 4QGEA 3TGGA 1SOJA 3SL3A 3HR1A 3SN7A 4LM0A 4PM0A 2QYMA 5K32A 4MVHA 3QI3A 3V94A 5C28A 4MSEA 1OYNA 4MRZA 3BJCA 3HDZA 3SL6A 3QI4A 1Y2HA 2H44A 4HTZA 4HF4A 4FCDA 3JWQA 3K3EA 4G2LA 1XN0A 3ECNA 3DYNA 3K4SA 3SL8A 4G2YA 3QPPA 5B4KA 1RO6A 1UDUA 5B4LA 1XONA 4MRWA 3G4IA 3G4KA 4P1RA 3HC8A 1T9RA 1XP0A 1Y2KA 2OUSA 3B2RA 1XMUA 3G58A 3IADA 3ITMA 5C2EA 1ZKLA 1TBFA 3W5EA 3IBJA 2O8HA 4MUWA 4LM4A 1XMYB 2H42A 4X0FA 3N3ZA 5B25A 3D3PA 3WYMA 4XY2A 2CHMA 4I9ZA 4G2WA 4NW7A 3O57A 3WYLA 3V9BA 4JIBA 3DY8A 4LLJA 4D09A 1Q9MA 1XM4A 4OEXA 4WZIA 5EDHA 5C1WA 5K1IA 3QPOA 1TB5A 2OVVA 4MD6A 3JWRA 3UI7A 3G4LA 4LLKA 5C2AA 4YQHA 4OEWA 4MSAA 4LM1A 1RKPA 3WYKA 1XLXA 5DH4A 4G2JA 3WI2A 3G3NA 1MKDA 1XOTA 4Y87A 1XORA 2QYLA 4PHLA 4W1OA 1XOQA
chains in the Genus database with same CATH topology
1Y2CA 2OUYA 3LXGA 4Y86A 5EDEB 4AJDA 4HTXA 2OUQA 5I2RA 1RORA 2FM0A 1SO2A 4FCBA 4E90A 1TB7A 4P0NA 3HQYA 3V93A 3DYQA 4GH6A 2PW3A 2QYNA 4Y8CA 3I8VA 3KKTA 2OUNA 4MSHA 4TPMA 1XOMA 5EDGB 5EDIB 2OUUA 2H40A 4D08A 1PTWA 3FRGA 3G4GA 3HQZA 2OUVA 1XOSA 4MYQA 4C1IA 3SHYA 1UHOA 3DYSA 3JSIA 3HQWA 1XM6A 3IAKA 1XMYA 3QPNA 2WEYA 2OUPA 1Y2EA 4MSNA 2OVYA 2Y0JA 4IA0A 4NPWA 1ZKNA 2FM5A 3LY2A 1UDTA 1XMUB 2OURA 4DFFA 3SL4A 1Z1LA 2R8QA 3K3HA 4WN1A 5C2HA 3O56A 4I15A 3SNLA 4TPPA 4BBXA 1XLZA 3GWTA 3ITUA 3JSWA 4Y2BA 4NPVA 4AJFA 4LLXA 1Y2JA 4KP6A 5DH5A 4ZO5A 3WS9A 4LLPA 1F0JA 1TBBA 5AXPA 1Y2DA 1XM4B 1XOZA 3DYLA 3ECMA 3HMVA 3WS8A 3O0JA 5AXQA 5EDEA 1Y2BA 2HD1A 4MS0A 4PHWA 5K9RA 4WCUA 3G45A 1TAZA 4DDLA 1RO9A 1T9SA 3UUOA 4AELA 3SNIA 3WD9A 5C29A 4AJGA 4AJMA 3TGEA 3SIEA 4LKQA 4LM3A 2QYKA 3TVXA 4OGBA 2YY2A 4HEUA 3SHZA 5EDIA 4MSCA 5EDGA 4LM2A 3SL5A 4YS7A 4QGEA 3TGGA 1SOJA 3SL3A 3HR1A 3SN7A 4LM0A 4PM0A 2QYMA 5K32A 4MVHA 3QI3A 3V94A 5C28A 4MSEA 1OYNA 4MRZA 3BJCA 3HDZA 3SL6A 3QI4A 1Y2HA 2H44A 4HTZA 4HF4A 4FCDA 3JWQA 3K3EA 4G2LA 1XN0A 3ECNA 3DYNA 3K4SA 3SL8A 4G2YA 3QPPA 5B4KA 1RO6A 1UDUA 5B4LA 1XONA 4MRWA 3G4IA 3G4KA 4P1RA 3HC8A 1T9RA 1XP0A 1Y2KA 2OUSA 3B2RA 1XMUA 3G58A 3IADA 3ITMA 5C2EA 1ZKLA 1TBFA 3W5EA 3IBJA 2O8HA 4MUWA 4LM4A 1XMYB 2H42A 4X0FA 3N3ZA 5B25A 3D3PA 3WYMA 4XY2A 2CHMA 4I9ZA 4G2WA 4NW7A 3O57A 3WYLA 3V9BA 4JIBA 3DY8A 4LLJA 4D09A 1Q9MA 1XM4A 4OEXA 4WZIA 5EDHA 5C1WA 5K1IA 3QPOA 1TB5A 2OVVA 4MD6A 3JWRA 3UI7A 3G4LA 4LLKA 5C2AA 4YQHA 4OEWA 4MSAA 4LM1A 1RKPA 3WYKA 1XLXA 5DH4A 4G2JA 3WI2A 3G3NA 1MKDA 1XOTA 4Y87A 1XORA 2QYLA 4PHLA 4W1OA 1XOQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y2C A;  2OUY A;  3LXG A;  4Y86 A;  5EDE B;  4AJD A;  4HTX A;  2OUQ A;  5I2R A;  1ROR A;  2FM0 A;  1SO2 A;  4FCB A;  4E90 A;  1TB7 A;  4P0N A;  3HQY A;  3V93 A;  3DYQ A;  4GH6 A;  2PW3 A;  2QYN A;  4Y8C A;  3I8V A;  3KKT A;  2OUN A;  4MSH A;  4TPM A;  1XOM A;  5EDG B;  5EDI B;  2OUU A;  2H40 A;  4D08 A;  1PTW A;  3FRG A;  3G4G A;  3HQZ A;  2OUV A;  1XOS A;  4MYQ A;  4C1I A;  3SHY A;  1UHO A;  3DYS A;  3JSI A;  3HQW A;  1XM6 A;  3IAK A;  1XMY A;  3QPN A;  2WEY A;  2OUP A;  1Y2E A;  4MSN A;  2OVY A;  2Y0J A;  4IA0 A;  4NPW A;  1ZKN A;  2FM5 A;  3LY2 A;  1UDT A;  1XMU B;  2OUR A;  4DFF A;  3SL4 A;  1Z1L A;  2R8Q A;  3K3H A;  4WN1 A;  5C2H A;  3O56 A;  4I15 A;  3SNL A;  4TPP A;  4BBX A;  1XLZ A;  3GWT A;  3ITU A;  3JSW A;  4Y2B A;  4NPV A;  4AJF A;  4LLX A;  1Y2J A;  4KP6 A;  5DH5 A;  4ZO5 A;  3WS9 A;  4LLP A;  1F0J A;  1TBB A;  5AXP A;  1Y2D A;  1XM4 B;  1XOZ A;  3DYL A;  3ECM A;  3HMV A;  3WS8 A;  3O0J A;  5AXQ A;  5EDE A;  1Y2B A;  2HD1 A;  4MS0 A;  4PHW A;  5K9R A;  4WCU A;  3G45 A;  1TAZ A;  4DDL A;  1RO9 A;  1T9S A;  3UUO A;  4AEL A;  3SNI A;  3WD9 A;  5C29 A;  4AJG A;  4AJM A;  3TGE A;  3SIE A;  4LKQ A;  4LM3 A;  2QYK A;  3TVX A;  4OGB A;  2YY2 A;  4HEU A;  3SHZ A;  5EDI A;  4MSC A;  5EDG A;  4LM2 A;  3SL5 A;  4YS7 A;  4QGE A;  3TGG A;  1SOJ A;  3SL3 A;  3HR1 A;  3SN7 A;  4LM0 A;  4PM0 A;  2QYM A;  5K32 A;  4MVH A;  3QI3 A;  3V94 A;  5C28 A;  4MSE A;  1OYN A;  4MRZ A;  3BJC A;  3HDZ A;  3SL6 A;  3QI4 A;  1Y2H A;  2H44 A;  4HTZ A;  4HF4 A;  4FCD A;  3JWQ A;  3K3E A;  4G2L A;  1XN0 A;  3ECN A;  3DYN A;  3K4S A;  3SL8 A;  4G2Y A;  3QPP A;  5B4K A;  1RO6 A;  1UDU A;  5B4L A;  1XON A;  4MRW A;  3G4I A;  3G4K A;  4P1R A;  3HC8 A;  1T9R A;  1XP0 A;  1Y2K A;  2OUS A;  3B2R A;  1XMU A;  3G58 A;  3IAD A;  3ITM A;  5C2E A;  1ZKL A;  1TBF A;  3W5E A;  3IBJ A;  2O8H A;  4MUW A;  4LM4 A;  1XMY B;  2H42 A;  4X0F A;  3N3Z A;  5B25 A;  3D3P A;  3WYM A;  4XY2 A;  2CHM A;  4I9Z A;  4G2W A;  4NW7 A;  3O57 A;  3WYL A;  3V9B A;  4JIB A;  3DY8 A;  4LLJ A;  4D09 A;  1Q9M A;  1XM4 A;  4OEX A;  4WZI A;  5EDH A;  5C1W A;  5K1I A;  3QPO A;  1TB5 A;  2OVV A;  4MD6 A;  3JWR A;  3UI7 A;  3G4L A;  4LLK A;  5C2A A;  4YQH A;  4OEW A;  4MSA A;  4LM1 A;  1RKP A;  3WYK A;  1XLX A;  5DH4 A;  4G2J A;  3WI2 A;  3G3N A;  1MKD A;  1XOT A;  4Y87 A;  1XOR A;  2QYL A;  4PHL A;  4W1O A;  1XOQ A; 
#chains in the Genus database with same CATH topology
 1Y2C A;  2OUY A;  3LXG A;  4Y86 A;  5EDE B;  4AJD A;  4HTX A;  2OUQ A;  5I2R A;  1ROR A;  2FM0 A;  1SO2 A;  4FCB A;  4E90 A;  1TB7 A;  4P0N A;  3HQY A;  3V93 A;  3DYQ A;  4GH6 A;  2PW3 A;  2QYN A;  4Y8C A;  3I8V A;  3KKT A;  2OUN A;  4MSH A;  4TPM A;  1XOM A;  5EDG B;  5EDI B;  2OUU A;  2H40 A;  4D08 A;  1PTW A;  3FRG A;  3G4G A;  3HQZ A;  2OUV A;  1XOS A;  4MYQ A;  4C1I A;  3SHY A;  1UHO A;  3DYS A;  3JSI A;  3HQW A;  1XM6 A;  3IAK A;  1XMY A;  3QPN A;  2WEY A;  2OUP A;  1Y2E A;  4MSN A;  2OVY A;  2Y0J A;  4IA0 A;  4NPW A;  1ZKN A;  2FM5 A;  3LY2 A;  1UDT A;  1XMU B;  2OUR A;  4DFF A;  3SL4 A;  1Z1L A;  2R8Q A;  3K3H A;  4WN1 A;  5C2H A;  3O56 A;  4I15 A;  3SNL A;  4TPP A;  4BBX A;  1XLZ A;  3GWT A;  3ITU A;  3JSW A;  4Y2B A;  4NPV A;  4AJF A;  4LLX A;  1Y2J A;  4KP6 A;  5DH5 A;  4ZO5 A;  3WS9 A;  4LLP A;  1F0J A;  1TBB A;  5AXP A;  1Y2D A;  1XM4 B;  1XOZ A;  3DYL A;  3ECM A;  3HMV A;  3WS8 A;  3O0J A;  5AXQ A;  5EDE A;  1Y2B A;  2HD1 A;  4MS0 A;  4PHW A;  5K9R A;  4WCU A;  3G45 A;  1TAZ A;  4DDL A;  1RO9 A;  1T9S A;  3UUO A;  4AEL A;  3SNI A;  3WD9 A;  5C29 A;  4AJG A;  4AJM A;  3TGE A;  3SIE A;  4LKQ A;  4LM3 A;  2QYK A;  3TVX A;  4OGB A;  2YY2 A;  4HEU A;  3SHZ A;  5EDI A;  4MSC A;  5EDG A;  4LM2 A;  3SL5 A;  4YS7 A;  4QGE A;  3TGG A;  1SOJ A;  3SL3 A;  3HR1 A;  3SN7 A;  4LM0 A;  4PM0 A;  2QYM A;  5K32 A;  4MVH A;  3QI3 A;  3V94 A;  5C28 A;  4MSE A;  1OYN A;  4MRZ A;  3BJC A;  3HDZ A;  3SL6 A;  3QI4 A;  1Y2H A;  2H44 A;  4HTZ A;  4HF4 A;  4FCD A;  3JWQ A;  3K3E A;  4G2L A;  1XN0 A;  3ECN A;  3DYN A;  3K4S A;  3SL8 A;  4G2Y A;  3QPP A;  5B4K A;  1RO6 A;  1UDU A;  5B4L A;  1XON A;  4MRW A;  3G4I A;  3G4K A;  4P1R A;  3HC8 A;  1T9R A;  1XP0 A;  1Y2K A;  2OUS A;  3B2R A;  1XMU A;  3G58 A;  3IAD A;  3ITM A;  5C2E A;  1ZKL A;  1TBF A;  3W5E A;  3IBJ A;  2O8H A;  4MUW A;  4LM4 A;  1XMY B;  2H42 A;  4X0F A;  3N3Z A;  5B25 A;  3D3P A;  3WYM A;  4XY2 A;  2CHM A;  4I9Z A;  4G2W A;  4NW7 A;  3O57 A;  3WYL A;  3V9B A;  4JIB A;  3DY8 A;  4LLJ A;  4D09 A;  1Q9M A;  1XM4 A;  4OEX A;  4WZI A;  5EDH A;  5C1W A;  5K1I A;  3QPO A;  1TB5 A;  2OVV A;  4MD6 A;  3JWR A;  3UI7 A;  3G4L A;  4LLK A;  5C2A A;  4YQH A;  4OEW A;  4MSA A;  4LM1 A;  1RKP A;  3WYK A;  1XLX A;  5DH4 A;  4G2J A;  3WI2 A;  3G3N A;  1MKD A;  1XOT A;  4Y87 A;  1XOR A;  2QYL A;  4PHL A;  4W1O A;  1XOQ A; 
#chains in the Genus database with same CATH homology
 1Y2C A;  2OUY A;  3LXG A;  4Y86 A;  5EDE B;  4AJD A;  4HTX A;  2OUQ A;  5I2R A;  1ROR A;  2FM0 A;  1SO2 A;  4FCB A;  4E90 A;  1TB7 A;  4P0N A;  3HQY A;  3V93 A;  3DYQ A;  4GH6 A;  2PW3 A;  2QYN A;  4Y8C A;  3I8V A;  3KKT A;  2OUN A;  4MSH A;  4TPM A;  1XOM A;  5EDG B;  5EDI B;  2OUU A;  2H40 A;  4D08 A;  1PTW A;  3FRG A;  3G4G A;  3HQZ A;  2OUV A;  1XOS A;  4MYQ A;  4C1I A;  3SHY A;  1UHO A;  3DYS A;  3JSI A;  3HQW A;  1XM6 A;  3IAK A;  1XMY A;  3QPN A;  2WEY A;  2OUP A;  1Y2E A;  4MSN A;  2OVY A;  2Y0J A;  4IA0 A;  4NPW A;  1ZKN A;  2FM5 A;  3LY2 A;  1UDT A;  1XMU B;  2OUR A;  4DFF A;  3SL4 A;  1Z1L A;  2R8Q A;  3K3H A;  4WN1 A;  5C2H A;  3O56 A;  4I15 A;  3SNL A;  4TPP A;  4BBX A;  1XLZ A;  3GWT A;  3ITU A;  3JSW A;  4Y2B A;  4NPV A;  4AJF A;  4LLX A;  1Y2J A;  4KP6 A;  5DH5 A;  4ZO5 A;  3WS9 A;  4LLP A;  1F0J A;  1TBB A;  5AXP A;  1Y2D A;  1XM4 B;  1XOZ A;  3DYL A;  3ECM A;  3HMV A;  3WS8 A;  3O0J A;  5AXQ A;  5EDE A;  1Y2B A;  2HD1 A;  4MS0 A;  4PHW A;  5K9R A;  4WCU A;  3G45 A;  1TAZ A;  4DDL A;  1RO9 A;  1T9S A;  3UUO A;  4AEL A;  3SNI A;  3WD9 A;  5C29 A;  4AJG A;  4AJM A;  3TGE A;  3SIE A;  4LKQ A;  4LM3 A;  2QYK A;  3TVX A;  4OGB A;  2YY2 A;  4HEU A;  3SHZ A;  5EDI A;  4MSC A;  5EDG A;  4LM2 A;  3SL5 A;  4YS7 A;  4QGE A;  3TGG A;  1SOJ A;  3SL3 A;  3HR1 A;  3SN7 A;  4LM0 A;  4PM0 A;  2QYM A;  5K32 A;  4MVH A;  3QI3 A;  3V94 A;  5C28 A;  4MSE A;  1OYN A;  4MRZ A;  3BJC A;  3HDZ A;  3SL6 A;  3QI4 A;  1Y2H A;  2H44 A;  4HTZ A;  4HF4 A;  4FCD A;  3JWQ A;  3K3E A;  4G2L A;  1XN0 A;  3ECN A;  3DYN A;  3K4S A;  3SL8 A;  4G2Y A;  3QPP A;  5B4K A;  1RO6 A;  1UDU A;  5B4L A;  1XON A;  4MRW A;  3G4I A;  3G4K A;  4P1R A;  3HC8 A;  1T9R A;  1XP0 A;  1Y2K A;  2OUS A;  3B2R A;  1XMU A;  3G58 A;  3IAD A;  3ITM A;  5C2E A;  1ZKL A;  1TBF A;  3W5E A;  3IBJ A;  2O8H A;  4MUW A;  4LM4 A;  1XMY B;  2H42 A;  4X0F A;  3N3Z A;  5B25 A;  3D3P A;  3WYM A;  4XY2 A;  2CHM A;  4I9Z A;  4G2W A;  4NW7 A;  3O57 A;  3WYL A;  3V9B A;  4JIB A;  3DY8 A;  4LLJ A;  4D09 A;  1Q9M A;  1XM4 A;  4OEX A;  4WZI A;  5EDH A;  5C1W A;  5K1I A;  3QPO A;  1TB5 A;  2OVV A;  4MD6 A;  3JWR A;  3UI7 A;  3G4L A;  4LLK A;  5C2A A;  4YQH A;  4OEW A;  4MSA A;  4LM1 A;  1RKP A;  3WYK A;  1XLX A;  5DH4 A;  4G2J A;  3WI2 A;  3G3N A;  1MKD A;  1XOT A;  4Y87 A;  1XOR A;  2QYL A;  4PHL A;  4W1O A;  1XOQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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