4NWPA

Computationally designed two-component self-assembling tetrahedral cage, t33-21, crystallized in space group r32
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
146
structure length
145
Chain Sequence
KDSPIIEANGTLDELTSFIGEAKHYVDEEMKGILEEIQNDIYKIMGEIGSKGKIEGISEERIAWLLKLILRYMEMVNLSFVLPGGTLESAKLDVCRTIARRALRKVLTVTREFGIGAEAAAYLLALSDLLFLLARVIEIEKNKLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Accurate design of co-assembling multi-component protein nanomaterials.
pubmed doi rcsb
molecule tags Protein binding
source organism Pyrococcus horikoshii
molecule keywords Putative uncharacterized protein
total genus 63
structure length 145
sequence length 146
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01923 Cob_adeno_trans Cobalamin adenosyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1200.10 Mainly Alpha Up-down Bundle Hypothetical Protein Ta1238; Chain: A; Cobalamin adenosyltransferase-like 4nwpA00
3KE5A 3CI3A 3CI4A 2R6TA 4NWPA 2NT8A 2AH6A 3KE4A 2R6XA 1RTYA 4NWQA 3CI1A 2ZHZA 2G2DA 2ZHYA 3GAHA 2IDXA 1WY1A 1WOZA 5CY5B 1WVTA 3GAIA 5CY5A 1NOGA 1NIGA 3GAJA
chains in the Genus database with same CATH superfamily
3KE5A 3CI3A 3CI4A 2R6TA 4NWPA 2NT8A 2AH6A 3KE4A 2R6XA 1RTYA 4NWQA 3CI1A 2ZHZA 2G2DA 2ZHYA 3GAHA 2IDXA 1WY1A 1WOZA 5CY5B 1WVTA 3GAIA 5CY5A 1NOGA 1NIGA 3GAJA
chains in the Genus database with same CATH topology
3KE5A 3CI3A 3CI4A 2R6TA 4NWPA 2NT8A 2AH6A 3KE4A 2R6XA 1RTYA 4NWQA 3CI1A 2ZHZA 2G2DA 2ZHYA 3GAHA 2IDXA 1WY1A 1WOZA 5CY5B 1WVTA 3GAIA 5CY5A 1NOGA 1NIGA 3GAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KE5 A;  3CI3 A;  3CI4 A;  2R6T A;  4NWP A;  2NT8 A;  2AH6 A;  3KE4 A;  2R6X A;  1RTY A;  4NWQ A;  3CI1 A;  2ZHZ A;  2G2D A;  2ZHY A;  3GAH A;  2IDX A;  1WY1 A;  1WOZ A;  5CY5 B;  1WVT A;  3GAI A;  5CY5 A;  1NOG A;  1NIG A;  3GAJ A; 
#chains in the Genus database with same CATH topology
 3KE5 A;  3CI3 A;  3CI4 A;  2R6T A;  4NWP A;  2NT8 A;  2AH6 A;  3KE4 A;  2R6X A;  1RTY A;  4NWQ A;  3CI1 A;  2ZHZ A;  2G2D A;  2ZHY A;  3GAH A;  2IDX A;  1WY1 A;  1WOZ A;  5CY5 B;  1WVT A;  3GAI A;  5CY5 A;  1NOG A;  1NIG A;  3GAJ A; 
#chains in the Genus database with same CATH homology
 3KE5 A;  3CI3 A;  3CI4 A;  2R6T A;  4NWP A;  2NT8 A;  2AH6 A;  3KE4 A;  2R6X A;  1RTY A;  4NWQ A;  3CI1 A;  2ZHZ A;  2G2D A;  2ZHY A;  3GAH A;  2IDX A;  1WY1 A;  1WOZ A;  5CY5 B;  1WVT A;  3GAI A;  5CY5 A;  1NOG A;  1NIG A;  3GAJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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