4POVA

Thit with lmg135 bound
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
178
structure length
178
Chain Sequence
KFNVRLLTEIAFMAALAFIISLIPNTVYGWIIVEIACIPILLLSLRRGLTAGLVGGLIWGILSMITGHAYILSLSQAFLEYLVAPVSLGIAGLFRQKTAPLKLAPVLLGTFVAVLLKYFFHFIAGIIFWSQYAWKGWGAVAYSLAVNGISGILTAIAAFVILIIFVKKFPKLFIHSNY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Design of Potent Small-Molecule Binders to the S-Component of the ECF Transporter for Thiamine.
pubmed doi rcsb
molecule tags Protein binding
source organism Lactococcus lactis subsp. cremoris
molecule keywords Thiamine transporter ThiT
total genus 70
structure length 178
sequence length 178
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09515 Thia_YuaJ Thiamine transporter protein (Thia_YuaJ)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1760.20 Mainly Alpha Orthogonal Bundle Arp2/3 complex 21 kDa subunit ARPC3 Arp2/3 complex 21 kDa subunit ARPC3 4povA00
4TKRA 5D0YA 4HZUS 4MUUA 4MESA 4M5CA 5KC0A 4POVA 5KBWA 4DVEA 4M58A 4M5BA 4Z7FA 4N4DA 4RFSS 4MHWA 3P5NA 3RLBA 4POPA 5KC4A 4HUQS 5D3MC 5JSZC
chains in the Genus database with same CATH superfamily
4TKRA 5D0YA 4HZUS 3RSEE 4MUUA 4XEIE 4MESA 4M5CA 3UKRE 5KC0A 3ULEE 2P9KE 4POVA 3DXKE 5KBWA 4DVEA 4M58A 4JD2E 3UKUE 4M5BA 2P9SE 4Z7FA 2P9UE 4N4DA 4RFSS 1U2VE 4MHWA 2P9PE 3P5NA 1TYQE 4POPA 3RLBA 5KC4A 2P9NE 4HUQS 2P9LE 5D3MC 3DXME 2P9IE 1K8KE 5JSZC
chains in the Genus database with same CATH topology
4TKRA 5D0YA 4HZUS 4MUUA 4MESA 4M5CA 5KC0A 4POVA 5KBWA 4DVEA 4M58A 4M5BA 4Z7FA 4N4DA 4RFSS 4MHWA 3P5NA 3RLBA 4POPA 5KC4A 4HUQS 5D3MC 5JSZC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TKR A;  5D0Y A;  4HZU S;  4MUU A;  4MES A;  4M5C A;  5KC0 A;  4POV A;  5KBW A;  4DVE A;  4M58 A;  4M5B A;  4Z7F A;  4N4D A;  4RFS S;  4MHW A;  3P5N A;  3RLB A;  4POP A;  5KC4 A;  4HUQ S;  5D3M C;  5JSZ C; 
#chains in the Genus database with same CATH topology
 4TKR A;  5D0Y A;  4HZU S;  3RSE E;  4MUU A;  4XEI E;  4MES A;  4M5C A;  3UKR E;  5KC0 A;  3ULE E;  2P9K E;  4POV A;  3DXK E;  5KBW A;  4DVE A;  4M58 A;  4JD2 E;  3UKU E;  4M5B A;  2P9S E;  4Z7F A;  2P9U E;  4N4D A;  4RFS S;  1U2V E;  4MHW A;  2P9P E;  3P5N A;  1TYQ E;  4POP A;  3RLB A;  5KC4 A;  2P9N E;  4HUQ S;  2P9L E;  5D3M C;  3DXM E;  2P9I E;  1K8K E;  5JSZ C; 
#chains in the Genus database with same CATH homology
 4TKR A;  5D0Y A;  4HZU S;  4MUU A;  4MES A;  4M5C A;  5KC0 A;  4POV A;  5KBW A;  4DVE A;  4M58 A;  4M5B A;  4Z7F A;  4N4D A;  4RFS S;  4MHW A;  3P5N A;  3RLB A;  4POP A;  5KC4 A;  4HUQ S;  5D3M C;  5JSZ C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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