4WAMA

H. influenzae beta-carbonic anhydrase variant w39v/g41a/p48s/a49p
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
188
structure length
178
Chain Sequence
TPHYLVIACSDSRVSPEKLPGELFVHRNVANQVIHTDFNCLSVVQYAVDVLKIEHIIICGHTNCGGIHAAMADKDLGLINNWLLHIRDIWFKHGHLLGKLSPEKRADMLTKINVAEQVYNLGRTSIVKSAWERGQKLSLHGWVYGFLVGVMATSRETLEISYRNAIARLSILDEENIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Allosteric Reversion of Haemophilus influenzae beta-Carbonic Anhydrase via a Proline Shift.
pubmed doi rcsb
molecule tags Lyase
source organism Haemophilus influenzae
molecule keywords beta-carbonic anhydrase
total genus 66
structure length 178
sequence length 188
chains with identical sequence B
ec nomenclature ec 4.2.1.1: Carbonic anhydrase.
pdb deposition date 2014-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00484 Pro_CA Carbonic anhydrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1050.10 Alpha Beta 3-Layer(aba) Sandwich Beta-carbonic Anhydrase; Chain A Carbonic anhydrase 4wamA00
1T75A 5SWCA 4YF5A 3TENA 3UCOA 1I6OA 3E3IA 3EYXA 3UCJA 3E3FA 5CXKA 2W3NA 3MF3A 2A8CA 5JJ8A 4RXYA 3UCNA 3E3GA 1I6PA 2A8DA 4WAJA 3UCMA 5BQ1A 4O1JA 4O1KA 4WAKA 3E1WA 3TEOA 4YF6A 3E24A 3E2AA 2A5VA 2ESFA 1DDZA 1EKJA 3E2XA 3E1VA 1G5CA 3VQJA 4YF4A 3UCKA 3E31A 3LASA 3E28A 2W3QA 4WAMA 1YLKA 1YM3A 3QY1A 3E2WA 4ZNZA 3VRKA
chains in the Genus database with same CATH superfamily
1T75A 5SWCA 4YF5A 3TENA 3UCOA 1I6OA 3E3IA 3EYXA 3UCJA 3E3FA 5CXKA 2W3NA 3MF3A 2A8CA 5JJ8A 4RXYA 3UCNA 3E3GA 1I6PA 2A8DA 4WAJA 3UCMA 5BQ1A 4O1JA 4O1KA 4WAKA 3E1WA 3TEOA 4YF6A 3E24A 3E2AA 2A5VA 2ESFA 1DDZA 1EKJA 3E2XA 3E1VA 1G5CA 3VQJA 4YF4A 3UCKA 3E31A 3LASA 3E28A 2W3QA 4WAMA 1YLKA 1YM3A 3QY1A 3E2WA 4ZNZA 3VRKA
chains in the Genus database with same CATH topology
1T75A 5SWCA 4YF5A 3TENA 3UCOA 1I6OA 3E3IA 3EYXA 3UCJA 3E3FA 5CXKA 2W3NA 3MF3A 2A8CA 5JJ8A 4RXYA 3UCNA 3E3GA 1I6PA 2A8DA 4WAJA 3UCMA 5BQ1A 4O1JA 4O1KA 4WAKA 3E1WA 3TEOA 4YF6A 3E24A 3E2AA 2A5VA 2ESFA 1DDZA 1EKJA 3E2XA 3E1VA 1G5CA 3VQJA 4YF4A 3UCKA 3E31A 3LASA 3E28A 2W3QA 4WAMA 1YLKA 1YM3A 3QY1A 3E2WA 4ZNZA 3VRKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T75 A;  5SWC A;  4YF5 A;  3TEN A;  3UCO A;  1I6O A;  3E3I A;  3EYX A;  3UCJ A;  3E3F A;  5CXK A;  2W3N A;  3MF3 A;  2A8C A;  5JJ8 A;  4RXY A;  3UCN A;  3E3G A;  1I6P A;  2A8D A;  4WAJ A;  3UCM A;  5BQ1 A;  4O1J A;  4O1K A;  4WAK A;  3E1W A;  3TEO A;  4YF6 A;  3E24 A;  3E2A A;  2A5V A;  2ESF A;  1DDZ A;  1EKJ A;  3E2X A;  3E1V A;  1G5C A;  3VQJ A;  4YF4 A;  3UCK A;  3E31 A;  3LAS A;  3E28 A;  2W3Q A;  4WAM A;  1YLK A;  1YM3 A;  3QY1 A;  3E2W A;  4ZNZ A;  3VRK A; 
#chains in the Genus database with same CATH topology
 1T75 A;  5SWC A;  4YF5 A;  3TEN A;  3UCO A;  1I6O A;  3E3I A;  3EYX A;  3UCJ A;  3E3F A;  5CXK A;  2W3N A;  3MF3 A;  2A8C A;  5JJ8 A;  4RXY A;  3UCN A;  3E3G A;  1I6P A;  2A8D A;  4WAJ A;  3UCM A;  5BQ1 A;  4O1J A;  4O1K A;  4WAK A;  3E1W A;  3TEO A;  4YF6 A;  3E24 A;  3E2A A;  2A5V A;  2ESF A;  1DDZ A;  1EKJ A;  3E2X A;  3E1V A;  1G5C A;  3VQJ A;  4YF4 A;  3UCK A;  3E31 A;  3LAS A;  3E28 A;  2W3Q A;  4WAM A;  1YLK A;  1YM3 A;  3QY1 A;  3E2W A;  4ZNZ A;  3VRK A; 
#chains in the Genus database with same CATH homology
 1T75 A;  5SWC A;  4YF5 A;  3TEN A;  3UCO A;  1I6O A;  3E3I A;  3EYX A;  3UCJ A;  3E3F A;  5CXK A;  2W3N A;  3MF3 A;  2A8C A;  5JJ8 A;  4RXY A;  3UCN A;  3E3G A;  1I6P A;  2A8D A;  4WAJ A;  3UCM A;  5BQ1 A;  4O1J A;  4O1K A;  4WAK A;  3E1W A;  3TEO A;  4YF6 A;  3E24 A;  3E2A A;  2A5V A;  2ESF A;  1DDZ A;  1EKJ A;  3E2X A;  3E1V A;  1G5C A;  3VQJ A;  4YF4 A;  3UCK A;  3E31 A;  3LAS A;  3E28 A;  2W3Q A;  4WAM A;  1YLK A;  1YM3 A;  3QY1 A;  3E2W A;  4ZNZ A;  3VRK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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