4XL1B

Complex of notch1 (egf11-13) bound to delta-like 4 (n-egf1)
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
229
structure length
221
Chain Sequence
SSSIFQLRLQEFANERGMLANGRPCEPGCRTFFRICLHYQATFSEGPCTFGNVSTPVLGTNSFVIRDKNSGRNPLQLPLNFTWPGTFSLNIQAWHTPGDDLRPETSPGNSLISQIIIQGSLAVGNWKSDEQNNTLTRLRYSYRVVCSDNYYGDSCSRLCRDDHFGHYECQPDGSPSCLPGWTGYCDQPICLSGCHEQNGYCSPDECNCRPGWQGPLCNEAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
pubmed doi rcsb
molecule tags Protein binding
source organism Rattus norvegicus
molecule keywords Neurogenic locus notch homolog protein 1
total genus 39
structure length 221
sequence length 229
chains with identical sequence E
ec nomenclature
pdb deposition date 2015-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01414 DSL Delta serrate ligand
B PF07657 MNNL N terminus of Notch ligand
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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