4YFLE

Crystal structure of vh1-46 germline-derived cd4-binding site-directed antibody 1b2530 in complex with hiv-1 clade a/e 93th057 gp120
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
353
structure length
347
Chain Sequence
VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENFNMWKNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNGDIRKAYCEINGTKWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHHFNCRGEFFYCNTTQLFNNTCIGNETMKGCNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
pubmed doi rcsb
molecule tags Immune system
source organism Human immunodeficiency virus 1
molecule keywords Envelope glycoprotein gp160,Envelope glycoprotein gp160,Enve
total genus 68
structure length 347
sequence length 353
chains with identical sequence G
ec nomenclature
pdb deposition date 2015-02-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 4yflE01
4S1SG 4OM1G 4RFOG 4XVSG 5TE4G 4OLWG 1YYLG 3TIHA 2I5YG 3TGQA 5F4UA 4LSUG 4LSQG 4YDKG 1G9NG 4S1QG 4RWYA 3SE8G 4K0AA 5FECC 4YDLA 4RFNA 2I60G 5TE7G 4DKPA 3IDXG 5CAYG 2NY2A 4I53A 4LSSG 1RZJG 2NY7G 4OLYG 4LSPG 4KA2A 2NY5G 4LSVG 2BF1A 5IGXG 3JWOA 3SE9G 2NY6A 2NXYA 4JPVG 4DKQA 4DVWA 5F4PA 3HI1G 1RZKG 4XMPG 4R4NA 4JZZA 4R4FA 5FA2A 3TGTA 3IDYA 4JPWG 4P9HG 4DVXA 5I9QA 4JKPG 5F4LA 3FUSA 4OLUG 4YDIG 4JDTG 4I54A 4DKVA 1YYMG 2NY0A 4DVTA 2QADA 4YDJG 4DKRA 4DKOA 4XNZA 3NGBA 4DKUA 4S1RG 5CD5A 3JWDA 4LSTG 3TGSA 3LQAG 4LSRG 4OM0G 4R2GA 4RX4E 4DVVA 2NY1A 4XVTG 4DVRG 4RZ8A 5KJRG 2NY3A 2NXZA 3TGRA 1G9MG 4DVSA 4YE4G 4JB9G 4JZWA 4OLVG 5TE6G 2B4CG 4YFLE 4J6RG 5F9WA 4OLZG 4JM2E 5F4RA 3U7YG 4XNYG 5F9OG 3RJQA 1GC1G 5T33G 4OLXG 4LAJA 4H8WG 5F96G 2NY4A
chains in the Genus database with same CATH superfamily
4S1SG 4OM1G 4RFOG 4XVSG 5TE4G 4OLWG 1YYLG 3TIHA 2I5YG 3TGQA 5F4UA 4LSUG 4LSQG 4YDKG 1G9NG 4S1QG 4RWYA 3SE8G 4K0AA 5FECC 4YDLA 4RFNA 2I60G 5TE7G 4DKPA 3IDXG 5CAYG 2NY2A 4I53A 4LSSG 1RZJG 2NY7G 4OLYG 4LSPG 4KA2A 2NY5G 4LSVG 2BF1A 5IGXG 3JWOA 3SE9G 2NY6A 2NXYA 4JPVG 4DKQA 4DVWA 5F4PA 3HI1G 1RZKG 4XMPG 4R4NA 4JZZA 4R4FA 5FA2A 3TGTA 3IDYA 4JPWG 4P9HG 4DVXA 5I9QA 4JKPG 5F4LA 3FUSA 4OLUG 4YDIG 4JDTG 4I54A 4DKVA 1YYMG 2NY0A 4DVTA 2QADA 4YDJG 4DKRA 4DKOA 4XNZA 3NGBA 4DKUA 4S1RG 5CD5A 3JWDA 4LSTG 3TGSA 3LQAG 4LSRG 4OM0G 4R2GA 4RX4E 4DVVA 2NY1A 4XVTG 4DVRG 4RZ8A 5KJRG 2NY3A 2NXZA 3TGRA 1G9MG 4DVSA 4YE4G 4JB9G 4JZWA 4OLVG 5TE6G 2B4CG 4YFLE 4J6RG 5F9WA 4OLZG 4JM2E 5F4RA 3U7YG 4XNYG 5F9OG 3RJQA 1GC1G 5T33G 4OLXG 4LAJA 4H8WG 5F96G 2NY4A
chains in the Genus database with same CATH topology
4S1SG 4OM1G 4RFOG 4XVSG 5TE4G 4OLWG 1YYLG 3TIHA 2I5YG 3TGQA 5F4UA 4LSUG 4LSQG 4YDKG 1G9NG 4S1QG 4RWYA 3SE8G 4K0AA 5FECC 4YDLA 4RFNA 2I60G 5TE7G 4DKPA 3IDXG 5CAYG 2NY2A 4I53A 4LSSG 1RZJG 2NY7G 4OLYG 4LSPG 4KA2A 2NY5G 4LSVG 2BF1A 5IGXG 3JWOA 3SE9G 2NY6A 2NXYA 4JPVG 4DKQA 4DVWA 5F4PA 3HI1G 1RZKG 4XMPG 4R4NA 4JZZA 4R4FA 5FA2A 3TGTA 3IDYA 4JPWG 4P9HG 4DVXA 5I9QA 4JKPG 5F4LA 3FUSA 4OLUG 4YDIG 4JDTG 4I54A 4DKVA 1YYMG 2NY0A 4DVTA 2QADA 4YDJG 4DKRA 4DKOA 4XNZA 3NGBA 4DKUA 4S1RG 5CD5A 3JWDA 4LSTG 3TGSA 3LQAG 4LSRG 4OM0G 4R2GA 4RX4E 4DVVA 2NY1A 4XVTG 4DVRG 4RZ8A 5KJRG 2NY3A 2NXZA 3TGRA 1G9MG 4DVSA 4YE4G 4JB9G 4JZWA 4OLVG 5TE6G 2B4CG 4YFLE 4J6RG 5F9WA 4OLZG 4JM2E 5F4RA 3U7YG 4XNYG 5F9OG 3RJQA 1GC1G 5T33G 4OLXG 4LAJA 4H8WG 5F96G 2NY4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4S1S G;  4OM1 G;  4RFO G;  4XVS G;  5TE4 G;  4OLW G;  1YYL G;  3TIH A;  2I5Y G;  3TGQ A;  5F4U A;  4LSU G;  4LSQ G;  4YDK G;  1G9N G;  4S1Q G;  4RWY A;  3SE8 G;  4K0A A;  5FEC C;  4YDL A;  4RFN A;  2I60 G;  5TE7 G;  4DKP A;  3IDX G;  5CAY G;  2NY2 A;  4I53 A;  4LSS G;  1RZJ G;  2NY7 G;  4OLY G;  4LSP G;  4KA2 A;  2NY5 G;  4LSV G;  2BF1 A;  5IGX G;  3JWO A;  3SE9 G;  2NY6 A;  2NXY A;  4JPV G;  4DKQ A;  4DVW A;  5F4P A;  3HI1 G;  1RZK G;  4XMP G;  4R4N A;  4JZZ A;  4R4F A;  5FA2 A;  3TGT A;  3IDY A;  4JPW G;  4P9H G;  4DVX A;  5I9Q A;  4JKP G;  5F4L A;  3FUS A;  4OLU G;  4YDI G;  4JDT G;  4I54 A;  4DKV A;  1YYM G;  2NY0 A;  4DVT A;  2QAD A;  4YDJ G;  4DKR A;  4DKO A;  4XNZ A;  3NGB A;  4DKU A;  4S1R G;  5CD5 A;  3JWD A;  4LST G;  3TGS A;  3LQA G;  4LSR G;  4OM0 G;  4R2G A;  4RX4 E;  4DVV A;  2NY1 A;  4XVT G;  4DVR G;  4RZ8 A;  5KJR G;  2NY3 A;  2NXZ A;  3TGR A;  1G9M G;  4DVS A;  4YE4 G;  4JB9 G;  4JZW A;  4OLV G;  5TE6 G;  2B4C G;  4YFL E;  4J6R G;  5F9W A;  4OLZ G;  4JM2 E;  5F4R A;  3U7Y G;  4XNY G;  5F9O G;  3RJQ A;  1GC1 G;  5T33 G;  4OLX G;  4LAJ A;  4H8W G;  5F96 G;  2NY4 A; 
#chains in the Genus database with same CATH topology
 4S1S G;  4OM1 G;  4RFO G;  4XVS G;  5TE4 G;  4OLW G;  1YYL G;  3TIH A;  2I5Y G;  3TGQ A;  5F4U A;  4LSU G;  4LSQ G;  4YDK G;  1G9N G;  4S1Q G;  4RWY A;  3SE8 G;  4K0A A;  5FEC C;  4YDL A;  4RFN A;  2I60 G;  5TE7 G;  4DKP A;  3IDX G;  5CAY G;  2NY2 A;  4I53 A;  4LSS G;  1RZJ G;  2NY7 G;  4OLY G;  4LSP G;  4KA2 A;  2NY5 G;  4LSV G;  2BF1 A;  5IGX G;  3JWO A;  3SE9 G;  2NY6 A;  2NXY A;  4JPV G;  4DKQ A;  4DVW A;  5F4P A;  3HI1 G;  1RZK G;  4XMP G;  4R4N A;  4JZZ A;  4R4F A;  5FA2 A;  3TGT A;  3IDY A;  4JPW G;  4P9H G;  4DVX A;  5I9Q A;  4JKP G;  5F4L A;  3FUS A;  4OLU G;  4YDI G;  4JDT G;  4I54 A;  4DKV A;  1YYM G;  2NY0 A;  4DVT A;  2QAD A;  4YDJ G;  4DKR A;  4DKO A;  4XNZ A;  3NGB A;  4DKU A;  4S1R G;  5CD5 A;  3JWD A;  4LST G;  3TGS A;  3LQA G;  4LSR G;  4OM0 G;  4R2G A;  4RX4 E;  4DVV A;  2NY1 A;  4XVT G;  4DVR G;  4RZ8 A;  5KJR G;  2NY3 A;  2NXZ A;  3TGR A;  1G9M G;  4DVS A;  4YE4 G;  4JB9 G;  4JZW A;  4OLV G;  5TE6 G;  2B4C G;  4YFL E;  4J6R G;  5F9W A;  4OLZ G;  4JM2 E;  5F4R A;  3U7Y G;  4XNY G;  5F9O G;  3RJQ A;  1GC1 G;  5T33 G;  4OLX G;  4LAJ A;  4H8W G;  5F96 G;  2NY4 A; 
#chains in the Genus database with same CATH homology
 4S1S G;  4OM1 G;  4RFO G;  4XVS G;  5TE4 G;  4OLW G;  1YYL G;  3TIH A;  2I5Y G;  3TGQ A;  5F4U A;  4LSU G;  4LSQ G;  4YDK G;  1G9N G;  4S1Q G;  4RWY A;  3SE8 G;  4K0A A;  5FEC C;  4YDL A;  4RFN A;  2I60 G;  5TE7 G;  4DKP A;  3IDX G;  5CAY G;  2NY2 A;  4I53 A;  4LSS G;  1RZJ G;  2NY7 G;  4OLY G;  4LSP G;  4KA2 A;  2NY5 G;  4LSV G;  2BF1 A;  5IGX G;  3JWO A;  3SE9 G;  2NY6 A;  2NXY A;  4JPV G;  4DKQ A;  4DVW A;  5F4P A;  3HI1 G;  1RZK G;  4XMP G;  4R4N A;  4JZZ A;  4R4F A;  5FA2 A;  3TGT A;  3IDY A;  4JPW G;  4P9H G;  4DVX A;  5I9Q A;  4JKP G;  5F4L A;  3FUS A;  4OLU G;  4YDI G;  4JDT G;  4I54 A;  4DKV A;  1YYM G;  2NY0 A;  4DVT A;  2QAD A;  4YDJ G;  4DKR A;  4DKO A;  4XNZ A;  3NGB A;  4DKU A;  4S1R G;  5CD5 A;  3JWD A;  4LST G;  3TGS A;  3LQA G;  4LSR G;  4OM0 G;  4R2G A;  4RX4 E;  4DVV A;  2NY1 A;  4XVT G;  4DVR G;  4RZ8 A;  5KJR G;  2NY3 A;  2NXZ A;  3TGR A;  1G9M G;  4DVS A;  4YE4 G;  4JB9 G;  4JZW A;  4OLV G;  5TE6 G;  2B4C G;  4YFL E;  4J6R G;  5F9W A;  4OLZ G;  4JM2 E;  5F4R A;  3U7Y G;  4XNY G;  5F9O G;  3RJQ A;  1GC1 G;  5T33 G;  4OLX G;  4LAJ A;  4H8W G;  5F96 G;  2NY4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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