4YZSA

Crystal structures reveal transient perk luminal domain tetramerization in er stress signaling
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
297
structure length
200
Chain Sequence
SLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLKMIIPSLDGALFQWDRDRESMETVPFTVESLLESVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQLLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYKVSVADWKVMEWEYQFCTPIASAWLLKDGKVIPISIVEAARGATENSVYLGMYRGQLYLQSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Eukaryotic translation initiation factor 2-alpha kinase 3
total genus 30
structure length 200
sequence length 297
chains with identical sequence B
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2015-03-25
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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