4Z70A

Crystal structure of inorganic pyrophosphatase from mycobacterium tuberculosis in complex with ca ions
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
160
structure length
160
Chain Sequence
AMQFDVTIEIPKGQRNKYEVDHETGRVRLDRYLYTPMAYPTDYGFIEDTLGDDGDPLDALVLLPQPVFPGVLVAARPVGMFRMVDEHGGDDKVLCVPAGDPRWDHVQDIGDVPAFELDAIKHFFVHYKDLEPGKFVKAADWVDRAEAEAEVQRSVERFKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and computational dissection of the catalytic mechanism of the inorganic pyrophosphatase from Mycobacterium tuberculosis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
molecule keywords Inorganic pyrophosphatase
total genus 45
structure length 160
sequence length 160
chains with identical sequence B, C
ec nomenclature ec 3.6.1.1: Inorganic diphosphatase.
pdb deposition date 2015-04-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00719 Pyrophosphatase Inorganic pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.80.10 Alpha Beta Alpha-Beta Complex Inorganic Pyrophosphatase Inorganic pyrophosphatase 4z70A00
3Q4WA 2PRDA 3Q3LA 1YGZA 3Q46A 2IK4A 2IK6A 3EIYA 1JFDA 2BQYA 1E6AA 2AU6A 2IK0A 4Z71A 3EIZA 4ECPA 1WGIA 3LD3A 4Z74A 1PYPA 8PRKA 2AU8A 1I40A 1YPPA 2AUUA 4XELA 3Q5VA 3LO0A 1MJYA 1QEZA 4QMBA 1MJWA 4LUGA 1E9GA 3R5VA 1WCFA 1MJXA 3SW5A 1UDEA 1IPWA 2UXSA 3D63A 2EIPA 1HUKA 3I4QA 1FAJA 3FQ3A 2AU7A 3EJ0A 5KDEA 1HUJA 2IK7A 2BQXA 1IGPA 117EA 4Z73A 4Z72A 1INOA 5H4FA 3TR4A 2IK1A 3R5UA 1WGJA 1SXVA 2IHPA 3I98A 4Z70A 1OBWA 4UM4A 3EMJA 1M38A 5TEAA 2IK9A 1TWLA 3GVFA 3EJ2A 3D53A 1I6TA 3R6EA 1MJZA 4QLZA 2IK2A 5KDFA 2AU9A
chains in the Genus database with same CATH superfamily
3Q4WA 2PRDA 3Q3LA 1YGZA 3Q46A 2IK4A 2IK6A 3EIYA 1JFDA 2BQYA 1E6AA 2AU6A 2IK0A 4Z71A 3EIZA 4ECPA 1WGIA 3LD3A 4Z74A 1PYPA 8PRKA 2AU8A 1I40A 1YPPA 2AUUA 4XELA 3Q5VA 3LO0A 1MJYA 1QEZA 4QMBA 1MJWA 4LUGA 1E9GA 3R5VA 1WCFA 1MJXA 3SW5A 1UDEA 1IPWA 2UXSA 3D63A 2EIPA 1HUKA 3I4QA 1FAJA 3FQ3A 2AU7A 3EJ0A 5KDEA 1HUJA 2IK7A 2BQXA 1IGPA 117EA 4Z73A 4Z72A 1INOA 5H4FA 3TR4A 2IK1A 3R5UA 1WGJA 1SXVA 2IHPA 3I98A 4Z70A 1OBWA 4UM4A 3EMJA 1M38A 5TEAA 2IK9A 1TWLA 3GVFA 3EJ2A 3D53A 1I6TA 3R6EA 1MJZA 4QLZA 2IK2A 5KDFA 2AU9A
chains in the Genus database with same CATH topology
3Q4WA 2PRDA 3Q3LA 1YGZA 3Q46A 2IK4A 2IK6A 3EIYA 1JFDA 2BQYA 1E6AA 2AU6A 2IK0A 4Z71A 3EIZA 4ECPA 1WGIA 3LD3A 4Z74A 1PYPA 8PRKA 2AU8A 1I40A 1YPPA 2AUUA 4XELA 3Q5VA 3LO0A 1MJYA 1QEZA 4QMBA 1MJWA 4LUGA 1E9GA 3R5VA 1WCFA 1MJXA 3SW5A 1UDEA 1IPWA 2UXSA 3D63A 2EIPA 1HUKA 3I4QA 1FAJA 3FQ3A 2AU7A 3EJ0A 5KDEA 1HUJA 2IK7A 2BQXA 1IGPA 117EA 4Z73A 4Z72A 1INOA 5H4FA 3TR4A 2IK1A 3R5UA 1WGJA 1SXVA 2IHPA 3I98A 4Z70A 1OBWA 4UM4A 3EMJA 1M38A 5TEAA 2IK9A 1TWLA 3GVFA 3EJ2A 3D53A 1I6TA 3R6EA 1MJZA 4QLZA 2IK2A 5KDFA 2AU9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q4W A;  2PRD A;  3Q3L A;  1YGZ A;  3Q46 A;  2IK4 A;  2IK6 A;  3EIY A;  1JFD A;  2BQY A;  1E6A A;  2AU6 A;  2IK0 A;  4Z71 A;  3EIZ A;  4ECP A;  1WGI A;  3LD3 A;  4Z74 A;  1PYP A;  8PRK A;  2AU8 A;  1I40 A;  1YPP A;  2AUU A;  4XEL A;  3Q5V A;  3LO0 A;  1MJY A;  1QEZ A;  4QMB A;  1MJW A;  4LUG A;  1E9G A;  3R5V A;  1WCF A;  1MJX A;  3SW5 A;  1UDE A;  1IPW A;  2UXS A;  3D63 A;  2EIP A;  1HUK A;  3I4Q A;  1FAJ A;  3FQ3 A;  2AU7 A;  3EJ0 A;  5KDE A;  1HUJ A;  2IK7 A;  2BQX A;  1IGP A;  117E A;  4Z73 A;  4Z72 A;  1INO A;  5H4F A;  3TR4 A;  2IK1 A;  3R5U A;  1WGJ A;  1SXV A;  2IHP A;  3I98 A;  4Z70 A;  1OBW A;  4UM4 A;  3EMJ A;  1M38 A;  5TEA A;  2IK9 A;  1TWL A;  3GVF A;  3EJ2 A;  3D53 A;  1I6T A;  3R6E A;  1MJZ A;  4QLZ A;  2IK2 A;  5KDF A;  2AU9 A; 
#chains in the Genus database with same CATH topology
 3Q4W A;  2PRD A;  3Q3L A;  1YGZ A;  3Q46 A;  2IK4 A;  2IK6 A;  3EIY A;  1JFD A;  2BQY A;  1E6A A;  2AU6 A;  2IK0 A;  4Z71 A;  3EIZ A;  4ECP A;  1WGI A;  3LD3 A;  4Z74 A;  1PYP A;  8PRK A;  2AU8 A;  1I40 A;  1YPP A;  2AUU A;  4XEL A;  3Q5V A;  3LO0 A;  1MJY A;  1QEZ A;  4QMB A;  1MJW A;  4LUG A;  1E9G A;  3R5V A;  1WCF A;  1MJX A;  3SW5 A;  1UDE A;  1IPW A;  2UXS A;  3D63 A;  2EIP A;  1HUK A;  3I4Q A;  1FAJ A;  3FQ3 A;  2AU7 A;  3EJ0 A;  5KDE A;  1HUJ A;  2IK7 A;  2BQX A;  1IGP A;  117E A;  4Z73 A;  4Z72 A;  1INO A;  5H4F A;  3TR4 A;  2IK1 A;  3R5U A;  1WGJ A;  1SXV A;  2IHP A;  3I98 A;  4Z70 A;  1OBW A;  4UM4 A;  3EMJ A;  1M38 A;  5TEA A;  2IK9 A;  1TWL A;  3GVF A;  3EJ2 A;  3D53 A;  1I6T A;  3R6E A;  1MJZ A;  4QLZ A;  2IK2 A;  5KDF A;  2AU9 A; 
#chains in the Genus database with same CATH homology
 3Q4W A;  2PRD A;  3Q3L A;  1YGZ A;  3Q46 A;  2IK4 A;  2IK6 A;  3EIY A;  1JFD A;  2BQY A;  1E6A A;  2AU6 A;  2IK0 A;  4Z71 A;  3EIZ A;  4ECP A;  1WGI A;  3LD3 A;  4Z74 A;  1PYP A;  8PRK A;  2AU8 A;  1I40 A;  1YPP A;  2AUU A;  4XEL A;  3Q5V A;  3LO0 A;  1MJY A;  1QEZ A;  4QMB A;  1MJW A;  4LUG A;  1E9G A;  3R5V A;  1WCF A;  1MJX A;  3SW5 A;  1UDE A;  1IPW A;  2UXS A;  3D63 A;  2EIP A;  1HUK A;  3I4Q A;  1FAJ A;  3FQ3 A;  2AU7 A;  3EJ0 A;  5KDE A;  1HUJ A;  2IK7 A;  2BQX A;  1IGP A;  117E A;  4Z73 A;  4Z72 A;  1INO A;  5H4F A;  3TR4 A;  2IK1 A;  3R5U A;  1WGJ A;  1SXV A;  2IHP A;  3I98 A;  4Z70 A;  1OBW A;  4UM4 A;  3EMJ A;  1M38 A;  5TEA A;  2IK9 A;  1TWL A;  3GVF A;  3EJ2 A;  3D53 A;  1I6T A;  3R6E A;  1MJZ A;  4QLZ A;  2IK2 A;  5KDF A;  2AU9 A; 
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similar chains in the Genus database (?% sequence similarity)
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