4Z71A

Crystal structure of inorganic pyrophosphatase from mycobacterium tuberculosis in complex with mg ions
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
160
structure length
160
Chain Sequence
AMQFDVTIEIPKGQRNKYEVDHETGRVRLDRYLYTPMAYPTDYGFIEDTLGDDGDPLDALVLLPQPVFPGVLVAARPVGMFRMVDEHGGDDKVLCVPAGDPRWDHVQDIGDVPAFELDAIKHFFVHYKDLEPGKFVKAADWVDRAEAEAEVQRSVERFKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and computational dissection of the catalytic mechanism of the inorganic pyrophosphatase from Mycobacterium tuberculosis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
molecule keywords Inorganic pyrophosphatase
total genus 45
structure length 160
sequence length 160
chains with identical sequence B, C
ec nomenclature ec 3.6.1.1: Inorganic diphosphatase.
pdb deposition date 2015-04-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00719 Pyrophosphatase Inorganic pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.80.10 Alpha Beta Alpha-Beta Complex Inorganic Pyrophosphatase Inorganic pyrophosphatase 4z71A00
1WGJA 2AU9A 3EMJA 3R5VA 3EIYA 1E9GA 1IPWA 117EA 2IK7A 4QMBA 2IK9A 1INOA 2PRDA 1HUKA 1TWLA 1JFDA 3Q46A 2IK6A 2IHPA 3I98A 2AU6A 3LO0A 4UM4A 4Z72A 3R5UA 2EIPA 3GVFA 1I40A 4Z70A 1OBWA 8PRKA 3R6EA 2BQXA 1I6TA 3D53A 1MJXA 4Z73A 2IK2A 5H4FA 1IGPA 2IK4A 4QLZA 1QEZA 5KDEA 3D63A 3TR4A 1M38A 3FQ3A 3EJ0A 4ECPA 3Q5VA 3LD3A 2BQYA 1SXVA 3Q4WA 1FAJA 3Q3LA 1MJZA 4LUGA 2AU7A 4XELA 2IK0A 5KDFA 3EJ2A 1HUJA 1MJYA 1UDEA 4Z71A 1MJWA 1YGZA 2UXSA 1WCFA 3I4QA 1YPPA 1E6AA 5TEAA 2IK1A 2AU8A 3SW5A 3EIZA 2AUUA 4Z74A 1WGIA 1PYPA
chains in the Genus database with same CATH superfamily
1WGJA 2AU9A 3EMJA 3R5VA 3EIYA 1E9GA 1IPWA 117EA 2IK7A 4QMBA 2IK9A 1INOA 2PRDA 1HUKA 1TWLA 1JFDA 3Q46A 2IK6A 2IHPA 3I98A 2AU6A 3LO0A 4UM4A 4Z72A 3R5UA 2EIPA 3GVFA 1I40A 4Z70A 1OBWA 8PRKA 3R6EA 2BQXA 1I6TA 3D53A 1MJXA 4Z73A 2IK2A 5H4FA 1IGPA 2IK4A 4QLZA 1QEZA 5KDEA 3D63A 3TR4A 1M38A 3FQ3A 3EJ0A 4ECPA 3Q5VA 3LD3A 2BQYA 1SXVA 3Q4WA 1FAJA 3Q3LA 1MJZA 4LUGA 2AU7A 4XELA 2IK0A 5KDFA 3EJ2A 1HUJA 1MJYA 1UDEA 4Z71A 1MJWA 1YGZA 2UXSA 1WCFA 3I4QA 1YPPA 1E6AA 5TEAA 2IK1A 2AU8A 3SW5A 3EIZA 2AUUA 4Z74A 1WGIA 1PYPA
chains in the Genus database with same CATH topology
1WGJA 2AU9A 3EMJA 3R5VA 3EIYA 1E9GA 1IPWA 117EA 2IK7A 4QMBA 2IK9A 1INOA 2PRDA 1HUKA 1TWLA 1JFDA 3Q46A 2IK6A 2IHPA 3I98A 2AU6A 3LO0A 4UM4A 4Z72A 3R5UA 2EIPA 3GVFA 1I40A 4Z70A 1OBWA 8PRKA 3R6EA 2BQXA 1I6TA 3D53A 1MJXA 4Z73A 2IK2A 5H4FA 1IGPA 2IK4A 4QLZA 1QEZA 5KDEA 3D63A 3TR4A 1M38A 3FQ3A 3EJ0A 4ECPA 3Q5VA 3LD3A 2BQYA 1SXVA 3Q4WA 1FAJA 3Q3LA 1MJZA 4LUGA 2AU7A 4XELA 2IK0A 5KDFA 3EJ2A 1HUJA 1MJYA 1UDEA 4Z71A 1MJWA 1YGZA 2UXSA 1WCFA 3I4QA 1YPPA 1E6AA 5TEAA 2IK1A 2AU8A 3SW5A 3EIZA 2AUUA 4Z74A 1WGIA 1PYPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WGJ A;  2AU9 A;  3EMJ A;  3R5V A;  3EIY A;  1E9G A;  1IPW A;  117E A;  2IK7 A;  4QMB A;  2IK9 A;  1INO A;  2PRD A;  1HUK A;  1TWL A;  1JFD A;  3Q46 A;  2IK6 A;  2IHP A;  3I98 A;  2AU6 A;  3LO0 A;  4UM4 A;  4Z72 A;  3R5U A;  2EIP A;  3GVF A;  1I40 A;  4Z70 A;  1OBW A;  8PRK A;  3R6E A;  2BQX A;  1I6T A;  3D53 A;  1MJX A;  4Z73 A;  2IK2 A;  5H4F A;  1IGP A;  2IK4 A;  4QLZ A;  1QEZ A;  5KDE A;  3D63 A;  3TR4 A;  1M38 A;  3FQ3 A;  3EJ0 A;  4ECP A;  3Q5V A;  3LD3 A;  2BQY A;  1SXV A;  3Q4W A;  1FAJ A;  3Q3L A;  1MJZ A;  4LUG A;  2AU7 A;  4XEL A;  2IK0 A;  5KDF A;  3EJ2 A;  1HUJ A;  1MJY A;  1UDE A;  4Z71 A;  1MJW A;  1YGZ A;  2UXS A;  1WCF A;  3I4Q A;  1YPP A;  1E6A A;  5TEA A;  2IK1 A;  2AU8 A;  3SW5 A;  3EIZ A;  2AUU A;  4Z74 A;  1WGI A;  1PYP A; 
#chains in the Genus database with same CATH topology
 1WGJ A;  2AU9 A;  3EMJ A;  3R5V A;  3EIY A;  1E9G A;  1IPW A;  117E A;  2IK7 A;  4QMB A;  2IK9 A;  1INO A;  2PRD A;  1HUK A;  1TWL A;  1JFD A;  3Q46 A;  2IK6 A;  2IHP A;  3I98 A;  2AU6 A;  3LO0 A;  4UM4 A;  4Z72 A;  3R5U A;  2EIP A;  3GVF A;  1I40 A;  4Z70 A;  1OBW A;  8PRK A;  3R6E A;  2BQX A;  1I6T A;  3D53 A;  1MJX A;  4Z73 A;  2IK2 A;  5H4F A;  1IGP A;  2IK4 A;  4QLZ A;  1QEZ A;  5KDE A;  3D63 A;  3TR4 A;  1M38 A;  3FQ3 A;  3EJ0 A;  4ECP A;  3Q5V A;  3LD3 A;  2BQY A;  1SXV A;  3Q4W A;  1FAJ A;  3Q3L A;  1MJZ A;  4LUG A;  2AU7 A;  4XEL A;  2IK0 A;  5KDF A;  3EJ2 A;  1HUJ A;  1MJY A;  1UDE A;  4Z71 A;  1MJW A;  1YGZ A;  2UXS A;  1WCF A;  3I4Q A;  1YPP A;  1E6A A;  5TEA A;  2IK1 A;  2AU8 A;  3SW5 A;  3EIZ A;  2AUU A;  4Z74 A;  1WGI A;  1PYP A; 
#chains in the Genus database with same CATH homology
 1WGJ A;  2AU9 A;  3EMJ A;  3R5V A;  3EIY A;  1E9G A;  1IPW A;  117E A;  2IK7 A;  4QMB A;  2IK9 A;  1INO A;  2PRD A;  1HUK A;  1TWL A;  1JFD A;  3Q46 A;  2IK6 A;  2IHP A;  3I98 A;  2AU6 A;  3LO0 A;  4UM4 A;  4Z72 A;  3R5U A;  2EIP A;  3GVF A;  1I40 A;  4Z70 A;  1OBW A;  8PRK A;  3R6E A;  2BQX A;  1I6T A;  3D53 A;  1MJX A;  4Z73 A;  2IK2 A;  5H4F A;  1IGP A;  2IK4 A;  4QLZ A;  1QEZ A;  5KDE A;  3D63 A;  3TR4 A;  1M38 A;  3FQ3 A;  3EJ0 A;  4ECP A;  3Q5V A;  3LD3 A;  2BQY A;  1SXV A;  3Q4W A;  1FAJ A;  3Q3L A;  1MJZ A;  4LUG A;  2AU7 A;  4XEL A;  2IK0 A;  5KDF A;  3EJ2 A;  1HUJ A;  1MJY A;  1UDE A;  4Z71 A;  1MJW A;  1YGZ A;  2UXS A;  1WCF A;  3I4Q A;  1YPP A;  1E6A A;  5TEA A;  2IK1 A;  2AU8 A;  3SW5 A;  3EIZ A;  2AUU A;  4Z74 A;  1WGI A;  1PYP A; 
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