4ZDAA

Crystal structure of isocitrate dehydrogenase in complex with isocitrate and mn from m. smegmatis
Total Genus 263
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
263
sequence length
735
structure length
735
Chain Sequence
PTIIYTLTDEAPLLATYAFLPVVRKFAEAAGIDVKTSDISVAARILAEFGDHLTEEQRVPDNLGELGALTQDPSANIIKLPNISASVPQLLAAIKELQGKGYNVPDYPANPKTDDEKKIKDRYAKILGSAVNPVLREGNSDRRAPKAVKEYARKHPHSMGEWSQASRTHVATMKTGDFYHGEKSMTLDRDRRVKMVLKTKSGEEIVLKPEVKLDAGDIIDSMYMSKKALIAFYEEQIEDAYKTGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHEKLFDELGVNVNNGLSDLYDKIEALPASQREEIIEDLHKCHEHRPELAMVDSAKGISNFHSPSDVIVDASMPAMIRLGGKMYGADGRTKDTKAVNPESTFSRMYQEMINFCKTHGQFDPTTMGTVPNVGLMAQKAEEYGSHDKTFEIPEDGVADIVDIDTGEVLLTQNVEEGDIWRMPIVKDAPIRDWVKLAVTRARLSGMPVVFWLDTERPHEVELRKKVKEYLKDHDTEGLKIQIMPQVWAMRYTLERVVRGKDTIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVHQLVEENHLRWDSLGEFLALGASLEDMGNKTGNEKAKVLAKALDTATGKLLEENKSPSRRTGELDNRGSQFYLSLFWAQALAEQTEDAELAERFKPLAKALAEQEEAIVSELNSVQGKTVDIGGYYYPDPEKTSEVMRPSKTFNTTL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Oxidoreductase
molecule keywords Isocitrate dehydrogenase (NADP) Icd2
publication title crystal structure of isocitrate dehydrogenase in complex with isocitrate and Mn from M. smegmatis
rcsb
source organism Mycobacterium smegmatis
total genus 263
structure length 735
sequence length 735
chains with identical sequence B, C, D, E, F
ec nomenclature ec 1.1.1.42: Isocitrate dehydrogenase (NADP(+)).
pdb deposition date 2015-04-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03971 IDH Monomeric isocitrate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
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