5AE0A

Perdeuterated mouse cnpase catalytic domain at atomic resolution
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
217
structure length
217
Chain Sequence
KDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEPKEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
pubmed doi rcsb
molecule keywords 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE
molecule tags Hydrolase
source organism Mus musculus
total genus 57
structure length 217
sequence length 217
ec nomenclature ec 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
pdb deposition date 2015-08-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1740.10 Alpha Beta Alpha-Beta Complex 2',3'-cyclic nucleotide 3'-phosphodiesterase fold 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily 5ae0A00
4WDHA 2I3EA 4WC9A 3ZBZA 2YPCA 4WDGA 2Y3XA 4WBIA 2YDBA 2ILXA 4WCBA 4WFRA 2YOZA 4WCAA 4WEXA 1WOJA 5AE0A 4WDFA 2YPEA 2YDCA 2YQ9A 2Y1PA 4WDAA 2XMIA 2YDDA 2YP0A 2YPHA 4WDBA 4WDDA 4WDEA 4WCCA 3ZBRA 4WBLA 3ZBSA
chains in the Genus database with same CATH superfamily
4WDHA 2I3EA 4WC9A 3ZBZA 2YPCA 4WDGA 2Y3XA 4WBIA 2YDBA 2ILXA 4WCBA 4WFRA 2YOZA 4WCAA 4WEXA 1WOJA 5AE0A 4WDFA 2YPEA 2YDCA 2YQ9A 2Y1PA 4WDAA 2XMIA 2YDDA 2YP0A 2YPHA 4WDBA 4WDDA 4WDEA 4WCCA 3ZBRA 4WBLA 3ZBSA
chains in the Genus database with same CATH topology
4WDHA 2I3EA 4WC9A 3ZBZA 2YPCA 4WDGA 2Y3XA 4WBIA 2YDBA 2ILXA 4WCBA 4WFRA 2YOZA 4WCAA 4WEXA 1WOJA 5AE0A 4WDFA 2YPEA 2YDCA 2YQ9A 2Y1PA 4WDAA 2XMIA 2YDDA 2YP0A 2YPHA 4WDBA 4WDDA 4WDEA 4WCCA 3ZBRA 4WBLA 3ZBSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WDH A;  2I3E A;  4WC9 A;  3ZBZ A;  2YPC A;  4WDG A;  2Y3X A;  4WBI A;  2YDB A;  2ILX A;  4WCB A;  4WFR A;  2YOZ A;  4WCA A;  4WEX A;  1WOJ A;  5AE0 A;  4WDF A;  2YPE A;  2YDC A;  2YQ9 A;  2Y1P A;  4WDA A;  2XMI A;  2YDD A;  2YP0 A;  2YPH A;  4WDB A;  4WDD A;  4WDE A;  4WCC A;  3ZBR A;  4WBL A;  3ZBS A; 
#chains in the Genus database with same CATH topology
 4WDH A;  2I3E A;  4WC9 A;  3ZBZ A;  2YPC A;  4WDG A;  2Y3X A;  4WBI A;  2YDB A;  2ILX A;  4WCB A;  4WFR A;  2YOZ A;  4WCA A;  4WEX A;  1WOJ A;  5AE0 A;  4WDF A;  2YPE A;  2YDC A;  2YQ9 A;  2Y1P A;  4WDA A;  2XMI A;  2YDD A;  2YP0 A;  2YPH A;  4WDB A;  4WDD A;  4WDE A;  4WCC A;  3ZBR A;  4WBL A;  3ZBS A; 
#chains in the Genus database with same CATH homology
 4WDH A;  2I3E A;  4WC9 A;  3ZBZ A;  2YPC A;  4WDG A;  2Y3X A;  4WBI A;  2YDB A;  2ILX A;  4WCB A;  4WFR A;  2YOZ A;  4WCA A;  4WEX A;  1WOJ A;  5AE0 A;  4WDF A;  2YPE A;  2YDC A;  2YQ9 A;  2Y1P A;  4WDA A;  2XMI A;  2YDD A;  2YP0 A;  2YPH A;  4WDB A;  4WDD A;  4WDE A;  4WCC A;  3ZBR A;  4WBL A;  3ZBS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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