5EDDA

Crystal structure of mycobacterium tuberculosis dutpase r140k, h145w mutant
Total Genus 20
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
144
structure length
144
Chain Sequence
HSSGLVPRGSHMSTTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 20
structure length 144
sequence length 144
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2015-10-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 5eddA01
1SNFA 1RNJA 3HHQA 2HXDA 1SJNA 4AOOA 4AOZA 1Q5UX 3F4FA 3T70A 2PC5A 4AO5A 1SM8A 3ZEZA 2XY3A 3ZF4A 2YZJA 3MDXA 3TQ3A 3ZF3A 4A6AA 2BAZA 2QLPA 1DUDA 2WE1A 1VYQA 3LOJA 3ZF2A 3ZF0A 1EUWA 3I93A 3TRLA 1DUNA 1F7RA 3TRNA 1SEHA 1MQ7A 3T6YA 4GV8A 3H6XA 3TP1A 2WE2A 1DUTA 2D4LA 5CCTA 1XS4A 1F7NA 3CA9A 3H6DA 3TQ5A 2XCDA 2HQUA 2XX6A 3GF0A 3SO2A 3TPWA 2WE3A 1Q5HA 2HXBA 3ARAA 3P48A 1SIXA 4GK6A 2OKDA 1F7PA 5F9KA 1F7QA 2OL1A 1SMCA 1F7OA 3ARNA 3ZF5A 3HZAA 1OGHA 2HRMA 3T60A 3C3IA 2XCEA 4OOPA 1EU5A 1XS6A 2OKEA 1PKJA 3TTAA 5CCOA 2PY4A 1SLHA 3KM3A 3TPYA 2Y1TA 1PKKA 4WRKA 3T64A 2BT1A 2QXXA 2J4HA 3TSLA 4OOQA 1PKHA 1SYLA 1XS1A 2D4NA 4DHKA 4LHRA 4GCYA 2Y8CA 1F7KA 2V9XA 1RN8A 3TQ4A 1F7DA 3C2TA 3EHWA 3MBQA 2ZDCA 3ZF6A 4B0HA 2R9QA 3LQWA 1DUPA 3ZF1A 1DUCA 3TPNA 3ECYA 2HR6A 2BSYA 2OL0A 2J4QA 4XJCA 4APZ1 5ECTA 2OKBA 3TPSA 3TS6A 3TQZA 5EDDA 2WE0A 2D4MA
chains in the Genus database with same CATH superfamily
1SNFA 1RNJA 3HHQA 2HXDA 1SJNA 4AOOA 4AOZA 1Q5UX 3F4FA 3T70A 2PC5A 4AO5A 1SM8A 3ZEZA 2XY3A 3ZF4A 2YZJA 3MDXA 3TQ3A 3ZF3A 4A6AA 2BAZA 2QLPA 1DUDA 2WE1A 1VYQA 3LOJA 3ZF2A 3ZF0A 1EUWA 3I93A 3TRLA 1DUNA 1F7RA 3TRNA 1SEHA 1MQ7A 3T6YA 4GV8A 3H6XA 3TP1A 2WE2A 1DUTA 2D4LA 5CCTA 1XS4A 1F7NA 3CA9A 3H6DA 3TQ5A 2XCDA 2HQUA 2XX6A 3GF0A 3SO2A 3TPWA 2WE3A 1Q5HA 2HXBA 3ARAA 3P48A 1SIXA 4GK6A 2OKDA 1F7PA 5F9KA 1F7QA 2OL1A 1SMCA 1F7OA 3ARNA 3ZF5A 3HZAA 1OGHA 2HRMA 3T60A 3C3IA 2XCEA 4OOPA 1EU5A 1XS6A 2OKEA 1PKJA 3TTAA 5CCOA 2PY4A 1SLHA 3KM3A 3TPYA 2Y1TA 1PKKA 4WRKA 3T64A 2BT1A 2QXXA 2J4HA 3TSLA 4OOQA 1PKHA 1SYLA 1XS1A 2D4NA 4DHKA 4LHRA 4GCYA 2Y8CA 1F7KA 2V9XA 1RN8A 3TQ4A 1F7DA 3C2TA 3EHWA 1TULA 3MBQA 2ZDCA 3ZF6A 4B0HA 2R9QA 3LQWA 1DUPA 3ZF1A 1DUCA 3TPNA 3ECYA 2HR6A 2BSYA 2OL0A 2J4QA 4XJCA 4APZ1 5ECTA 2OKBA 3TPSA 3TS6A 3TQZA 5EDDA 2WE0A 2D4MA
chains in the Genus database with same CATH topology
1SNFA 1RNJA 3HHQA 2HXDA 1SJNA 4AOOA 4AOZA 1Q5UX 3F4FA 3T70A 2PC5A 4AO5A 1SM8A 3ZEZA 2XY3A 3ZF4A 2YZJA 3MDXA 3TQ3A 3ZF3A 4A6AA 2BAZA 2QLPA 1DUDA 2WE1A 1VYQA 3LOJA 3ZF2A 3ZF0A 1EUWA 3I93A 3TRLA 1DUNA 1F7RA 3TRNA 1SEHA 1MQ7A 3T6YA 4GV8A 3H6XA 3TP1A 2WE2A 1DUTA 2D4LA 5CCTA 1XS4A 1F7NA 3CA9A 3H6DA 3TQ5A 2XCDA 2HQUA 2XX6A 3GF0A 3SO2A 3TPWA 2WE3A 1Q5HA 2HXBA 3ARAA 3P48A 1SIXA 4GK6A 2OKDA 1F7PA 5F9KA 1F7QA 2OL1A 1SMCA 1F7OA 3ARNA 3ZF5A 3HZAA 1OGHA 2HRMA 3T60A 3C3IA 2XCEA 4OOPA 1EU5A 1XS6A 2OKEA 1PKJA 3TTAA 5CCOA 2PY4A 1SLHA 3KM3A 3TPYA 2Y1TA 1PKKA 4WRKA 3T64A 2BT1A 2QXXA 2J4HA 3TSLA 4OOQA 1PKHA 1SYLA 1XS1A 2D4NA 4DHKA 4LHRA 4GCYA 2Y8CA 1F7KA 2V9XA 1RN8A 3TQ4A 1F7DA 3C2TA 3EHWA 3MBQA 2ZDCA 3ZF6A 4B0HA 2R9QA 3LQWA 1DUPA 3ZF1A 1DUCA 3TPNA 3ECYA 2HR6A 2BSYA 2OL0A 2J4QA 4XJCA 4APZ1 5ECTA 2OKBA 3TPSA 3TS6A 3TQZA 5EDDA 2WE0A 2D4MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SNF A;  1RNJ A;  3HHQ A;  2HXD A;  1SJN A;  4AOO A;  4AOZ A;  1Q5U X;  3F4F A;  3T70 A;  2PC5 A;  4AO5 A;  1SM8 A;  3ZEZ A;  2XY3 A;  3ZF4 A;  2YZJ A;  3MDX A;  3TQ3 A;  3ZF3 A;  4A6A A;  2BAZ A;  2QLP A;  1DUD A;  2WE1 A;  1VYQ A;  3LOJ A;  3ZF2 A;  3ZF0 A;  1EUW A;  3I93 A;  3TRL A;  1DUN A;  1F7R A;  3TRN A;  1SEH A;  1MQ7 A;  3T6Y A;  4GV8 A;  3H6X A;  3TP1 A;  2WE2 A;  1DUT A;  2D4L A;  5CCT A;  1XS4 A;  1F7N A;  3CA9 A;  3H6D A;  3TQ5 A;  2XCD A;  2HQU A;  2XX6 A;  3GF0 A;  3SO2 A;  3TPW A;  2WE3 A;  1Q5H A;  2HXB A;  3ARA A;  3P48 A;  1SIX A;  4GK6 A;  2OKD A;  1F7P A;  5F9K A;  1F7Q A;  2OL1 A;  1SMC A;  1F7O A;  3ARN A;  3ZF5 A;  3HZA A;  1OGH A;  2HRM A;  3T60 A;  3C3I A;  2XCE A;  4OOP A;  1EU5 A;  1XS6 A;  2OKE A;  1PKJ A;  3TTA A;  5CCO A;  2PY4 A;  1SLH A;  3KM3 A;  3TPY A;  2Y1T A;  1PKK A;  4WRK A;  3T64 A;  2BT1 A;  2QXX A;  2J4H A;  3TSL A;  4OOQ A;  1PKH A;  1SYL A;  1XS1 A;  2D4N A;  4DHK A;  4LHR A;  4GCY A;  2Y8C A;  1F7K A;  2V9X A;  1RN8 A;  3TQ4 A;  1F7D A;  3C2T A;  3EHW A;  3MBQ A;  2ZDC A;  3ZF6 A;  4B0H A;  2R9Q A;  3LQW A;  1DUP A;  3ZF1 A;  1DUC A;  3TPN A;  3ECY A;  2HR6 A;  2BSY A;  2OL0 A;  2J4Q A;  4XJC A;  4APZ 1;  5ECT A;  2OKB A;  3TPS A;  3TS6 A;  3TQZ A;  5EDD A;  2WE0 A;  2D4M A; 
#chains in the Genus database with same CATH topology
 1SNF A;  1RNJ A;  3HHQ A;  2HXD A;  1SJN A;  4AOO A;  4AOZ A;  1Q5U X;  3F4F A;  3T70 A;  2PC5 A;  4AO5 A;  1SM8 A;  3ZEZ A;  2XY3 A;  3ZF4 A;  2YZJ A;  3MDX A;  3TQ3 A;  3ZF3 A;  4A6A A;  2BAZ A;  2QLP A;  1DUD A;  2WE1 A;  1VYQ A;  3LOJ A;  3ZF2 A;  3ZF0 A;  1EUW A;  3I93 A;  3TRL A;  1DUN A;  1F7R A;  3TRN A;  1SEH A;  1MQ7 A;  3T6Y A;  4GV8 A;  3H6X A;  3TP1 A;  2WE2 A;  1DUT A;  2D4L A;  5CCT A;  1XS4 A;  1F7N A;  3CA9 A;  3H6D A;  3TQ5 A;  2XCD A;  2HQU A;  2XX6 A;  3GF0 A;  3SO2 A;  3TPW A;  2WE3 A;  1Q5H A;  2HXB A;  3ARA A;  3P48 A;  1SIX A;  4GK6 A;  2OKD A;  1F7P A;  5F9K A;  1F7Q A;  2OL1 A;  1SMC A;  1F7O A;  3ARN A;  3ZF5 A;  3HZA A;  1OGH A;  2HRM A;  3T60 A;  3C3I A;  2XCE A;  4OOP A;  1EU5 A;  1XS6 A;  2OKE A;  1PKJ A;  3TTA A;  5CCO A;  2PY4 A;  1SLH A;  3KM3 A;  3TPY A;  2Y1T A;  1PKK A;  4WRK A;  3T64 A;  2BT1 A;  2QXX A;  2J4H A;  3TSL A;  4OOQ A;  1PKH A;  1SYL A;  1XS1 A;  2D4N A;  4DHK A;  4LHR A;  4GCY A;  2Y8C A;  1F7K A;  2V9X A;  1RN8 A;  3TQ4 A;  1F7D A;  3C2T A;  3EHW A;  1TUL A;  3MBQ A;  2ZDC A;  3ZF6 A;  4B0H A;  2R9Q A;  3LQW A;  1DUP A;  3ZF1 A;  1DUC A;  3TPN A;  3ECY A;  2HR6 A;  2BSY A;  2OL0 A;  2J4Q A;  4XJC A;  4APZ 1;  5ECT A;  2OKB A;  3TPS A;  3TS6 A;  3TQZ A;  5EDD A;  2WE0 A;  2D4M A; 
#chains in the Genus database with same CATH homology
 1SNF A;  1RNJ A;  3HHQ A;  2HXD A;  1SJN A;  4AOO A;  4AOZ A;  1Q5U X;  3F4F A;  3T70 A;  2PC5 A;  4AO5 A;  1SM8 A;  3ZEZ A;  2XY3 A;  3ZF4 A;  2YZJ A;  3MDX A;  3TQ3 A;  3ZF3 A;  4A6A A;  2BAZ A;  2QLP A;  1DUD A;  2WE1 A;  1VYQ A;  3LOJ A;  3ZF2 A;  3ZF0 A;  1EUW A;  3I93 A;  3TRL A;  1DUN A;  1F7R A;  3TRN A;  1SEH A;  1MQ7 A;  3T6Y A;  4GV8 A;  3H6X A;  3TP1 A;  2WE2 A;  1DUT A;  2D4L A;  5CCT A;  1XS4 A;  1F7N A;  3CA9 A;  3H6D A;  3TQ5 A;  2XCD A;  2HQU A;  2XX6 A;  3GF0 A;  3SO2 A;  3TPW A;  2WE3 A;  1Q5H A;  2HXB A;  3ARA A;  3P48 A;  1SIX A;  4GK6 A;  2OKD A;  1F7P A;  5F9K A;  1F7Q A;  2OL1 A;  1SMC A;  1F7O A;  3ARN A;  3ZF5 A;  3HZA A;  1OGH A;  2HRM A;  3T60 A;  3C3I A;  2XCE A;  4OOP A;  1EU5 A;  1XS6 A;  2OKE A;  1PKJ A;  3TTA A;  5CCO A;  2PY4 A;  1SLH A;  3KM3 A;  3TPY A;  2Y1T A;  1PKK A;  4WRK A;  3T64 A;  2BT1 A;  2QXX A;  2J4H A;  3TSL A;  4OOQ A;  1PKH A;  1SYL A;  1XS1 A;  2D4N A;  4DHK A;  4LHR A;  4GCY A;  2Y8C A;  1F7K A;  2V9X A;  1RN8 A;  3TQ4 A;  1F7D A;  3C2T A;  3EHW A;  3MBQ A;  2ZDC A;  3ZF6 A;  4B0H A;  2R9Q A;  3LQW A;  1DUP A;  3ZF1 A;  1DUC A;  3TPN A;  3ECY A;  2HR6 A;  2BSY A;  2OL0 A;  2J4Q A;  4XJC A;  4APZ 1;  5ECT A;  2OKB A;  3TPS A;  3TS6 A;  3TQZ A;  5EDD A;  2WE0 A;  2D4M A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...