5F4PA

Hiv-1 gp120 complex with bnm-iii-170
Total Genus 77
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
349
structure length
335
Chain Sequence
KTTLFCASDAKAYEKEVHNVWATHACVPTDPNPQEMVLANVTENFNMWKNDMVEQMHEDIISLWDESLKPCVKLTGGSAITQACPKVSFDPIPLHYCAPAGFAILKCNNKTFNGTGPCRNVSTVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNESVNIVCTRPNNIRQAHCNINESKWNNTLQKVGEELAKHFPSKTIKFEPSSGGDLEITTHSFNCRGEFFYCNTSDLFNGTYRNGTYNHTGRSSNGTITLQCKIKQIINMWQEVGRAIYAPPIEGEITCNSNITGLLLLRDDTETFRPGGGDMRDNWRSELYKYKVVE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition.
pubmed doi rcsb
molecule tags Viral protein
source organism Human immunodeficiency virus 1
molecule keywords ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C
total genus 77
structure length 335
sequence length 349
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-12-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 5f4pA01
2NXYA 4DKVA 4S1QG 4S1SG 2NY3A 4H8WG 5FA2A 4RFNA 4XNYG 4LSUG 4XVSG 3NGBA 2NY2A 4DKPA 4XMPG 4OM0G 4RFOG 4DVRG 5KJRG 5TE7G 3TGTA 5TE6G 4JZWA 2BF1A 5CD5A 4JPVG 2I5YG 5FECC 5F4PA 5F9OG 4R4FA 4LSSG 2NY5G 4JKPG 5CAYG 4S1RG 4DKUA 4LSQG 4OM1G 4JPWG 4I54A 5F4UA 2NY4A 2I60G 3JWDA 5F4LA 3U7YG 4OLXG 4LSRG 3TGQA 4KA2A 4YDKG 2QADA 2NY7G 2NXZA 4RX4E 4LSPG 4DKOA 4OLVG 3HI1G 4P9HG 3IDYA 3FUSA 5T33G 4DVWA 3LQAG 4JB9G 4DVSA 4YDLA 1RZKG 4YDJG 4JM2E 4DKRA 5F4RA 4DKQA 4I53A 1YYMG 3TGSA 4JZZA 4OLUG 4XNZA 4LSTG 4XVTG 4RWYA 1G9MG 2NY0A 4LAJA 4RZ8A 4DVTA 4DVXA 4J6RG 4R4NA 3TIHA 2B4CG 5TE4G 4YFLE 3SE8G 4K0AA 4OLZG 4YDIG 5IGXG 3RJQA 4YE4G 4OLWG 1YYLG 1RZJG 4LSVG 1GC1G 4OLYG 3TGRA 5I9QA 3IDXG 1G9NG 2NY6A 5F9WA 3JWOA 4DVVA 4R2GA 3SE9G 4JDTG 5F96G 2NY1A
chains in the Genus database with same CATH superfamily
2NXYA 4DKVA 4S1QG 4S1SG 2NY3A 4H8WG 5FA2A 4RFNA 4XNYG 4LSUG 4XVSG 3NGBA 2NY2A 4DKPA 4XMPG 4OM0G 4RFOG 4DVRG 5KJRG 5TE7G 3TGTA 5TE6G 4JZWA 2BF1A 5CD5A 4JPVG 2I5YG 5FECC 5F4PA 5F9OG 4R4FA 4LSSG 2NY5G 4JKPG 5CAYG 4S1RG 4DKUA 4LSQG 4OM1G 4JPWG 4I54A 5F4UA 2NY4A 2I60G 3JWDA 5F4LA 3U7YG 4OLXG 4LSRG 3TGQA 4KA2A 4YDKG 2QADA 2NY7G 2NXZA 4RX4E 4LSPG 4DKOA 4OLVG 3HI1G 4P9HG 3IDYA 3FUSA 5T33G 4DVWA 3LQAG 4JB9G 4DVSA 4YDLA 1RZKG 4YDJG 4JM2E 4DKRA 5F4RA 4DKQA 4I53A 1YYMG 3TGSA 4JZZA 4OLUG 4XNZA 4LSTG 4XVTG 4RWYA 1G9MG 2NY0A 4LAJA 4RZ8A 4DVTA 4DVXA 4J6RG 4R4NA 3TIHA 2B4CG 5TE4G 4YFLE 3SE8G 4K0AA 4OLZG 4YDIG 5IGXG 3RJQA 4YE4G 4OLWG 1YYLG 1RZJG 4LSVG 1GC1G 4OLYG 3TGRA 5I9QA 3IDXG 1G9NG 2NY6A 5F9WA 3JWOA 4DVVA 4R2GA 3SE9G 4JDTG 5F96G 2NY1A
chains in the Genus database with same CATH topology
2NXYA 4DKVA 4S1QG 4S1SG 2NY3A 4H8WG 5FA2A 4RFNA 4XNYG 4LSUG 4XVSG 3NGBA 2NY2A 4DKPA 4XMPG 4OM0G 4RFOG 4DVRG 5KJRG 5TE7G 3TGTA 5TE6G 4JZWA 2BF1A 5CD5A 4JPVG 2I5YG 5FECC 5F4PA 5F9OG 4R4FA 4LSSG 2NY5G 4JKPG 5CAYG 4S1RG 4DKUA 4LSQG 4OM1G 4JPWG 4I54A 5F4UA 2NY4A 2I60G 3JWDA 5F4LA 3U7YG 4OLXG 4LSRG 3TGQA 4KA2A 4YDKG 2QADA 2NY7G 2NXZA 4RX4E 4LSPG 4DKOA 4OLVG 3HI1G 4P9HG 3IDYA 3FUSA 5T33G 4DVWA 3LQAG 4JB9G 4DVSA 4YDLA 1RZKG 4YDJG 4JM2E 4DKRA 5F4RA 4DKQA 4I53A 1YYMG 3TGSA 4JZZA 4OLUG 4XNZA 4LSTG 4XVTG 4RWYA 1G9MG 2NY0A 4LAJA 4RZ8A 4DVTA 4DVXA 4J6RG 4R4NA 3TIHA 2B4CG 5TE4G 4YFLE 3SE8G 4K0AA 4OLZG 4YDIG 5IGXG 3RJQA 4YE4G 4OLWG 1YYLG 1RZJG 4LSVG 1GC1G 4OLYG 3TGRA 5I9QA 3IDXG 1G9NG 2NY6A 5F9WA 3JWOA 4DVVA 4R2GA 3SE9G 4JDTG 5F96G 2NY1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NXY A;  4DKV A;  4S1Q G;  4S1S G;  2NY3 A;  4H8W G;  5FA2 A;  4RFN A;  4XNY G;  4LSU G;  4XVS G;  3NGB A;  2NY2 A;  4DKP A;  4XMP G;  4OM0 G;  4RFO G;  4DVR G;  5KJR G;  5TE7 G;  3TGT A;  5TE6 G;  4JZW A;  2BF1 A;  5CD5 A;  4JPV G;  2I5Y G;  5FEC C;  5F4P A;  5F9O G;  4R4F A;  4LSS G;  2NY5 G;  4JKP G;  5CAY G;  4S1R G;  4DKU A;  4LSQ G;  4OM1 G;  4JPW G;  4I54 A;  5F4U A;  2NY4 A;  2I60 G;  3JWD A;  5F4L A;  3U7Y G;  4OLX G;  4LSR G;  3TGQ A;  4KA2 A;  4YDK G;  2QAD A;  2NY7 G;  2NXZ A;  4RX4 E;  4LSP G;  4DKO A;  4OLV G;  3HI1 G;  4P9H G;  3IDY A;  3FUS A;  5T33 G;  4DVW A;  3LQA G;  4JB9 G;  4DVS A;  4YDL A;  1RZK G;  4YDJ G;  4JM2 E;  4DKR A;  5F4R A;  4DKQ A;  4I53 A;  1YYM G;  3TGS A;  4JZZ A;  4OLU G;  4XNZ A;  4LST G;  4XVT G;  4RWY A;  1G9M G;  2NY0 A;  4LAJ A;  4RZ8 A;  4DVT A;  4DVX A;  4J6R G;  4R4N A;  3TIH A;  2B4C G;  5TE4 G;  4YFL E;  3SE8 G;  4K0A A;  4OLZ G;  4YDI G;  5IGX G;  3RJQ A;  4YE4 G;  4OLW G;  1YYL G;  1RZJ G;  4LSV G;  1GC1 G;  4OLY G;  3TGR A;  5I9Q A;  3IDX G;  1G9N G;  2NY6 A;  5F9W A;  3JWO A;  4DVV A;  4R2G A;  3SE9 G;  4JDT G;  5F96 G;  2NY1 A; 
#chains in the Genus database with same CATH topology
 2NXY A;  4DKV A;  4S1Q G;  4S1S G;  2NY3 A;  4H8W G;  5FA2 A;  4RFN A;  4XNY G;  4LSU G;  4XVS G;  3NGB A;  2NY2 A;  4DKP A;  4XMP G;  4OM0 G;  4RFO G;  4DVR G;  5KJR G;  5TE7 G;  3TGT A;  5TE6 G;  4JZW A;  2BF1 A;  5CD5 A;  4JPV G;  2I5Y G;  5FEC C;  5F4P A;  5F9O G;  4R4F A;  4LSS G;  2NY5 G;  4JKP G;  5CAY G;  4S1R G;  4DKU A;  4LSQ G;  4OM1 G;  4JPW G;  4I54 A;  5F4U A;  2NY4 A;  2I60 G;  3JWD A;  5F4L A;  3U7Y G;  4OLX G;  4LSR G;  3TGQ A;  4KA2 A;  4YDK G;  2QAD A;  2NY7 G;  2NXZ A;  4RX4 E;  4LSP G;  4DKO A;  4OLV G;  3HI1 G;  4P9H G;  3IDY A;  3FUS A;  5T33 G;  4DVW A;  3LQA G;  4JB9 G;  4DVS A;  4YDL A;  1RZK G;  4YDJ G;  4JM2 E;  4DKR A;  5F4R A;  4DKQ A;  4I53 A;  1YYM G;  3TGS A;  4JZZ A;  4OLU G;  4XNZ A;  4LST G;  4XVT G;  4RWY A;  1G9M G;  2NY0 A;  4LAJ A;  4RZ8 A;  4DVT A;  4DVX A;  4J6R G;  4R4N A;  3TIH A;  2B4C G;  5TE4 G;  4YFL E;  3SE8 G;  4K0A A;  4OLZ G;  4YDI G;  5IGX G;  3RJQ A;  4YE4 G;  4OLW G;  1YYL G;  1RZJ G;  4LSV G;  1GC1 G;  4OLY G;  3TGR A;  5I9Q A;  3IDX G;  1G9N G;  2NY6 A;  5F9W A;  3JWO A;  4DVV A;  4R2G A;  3SE9 G;  4JDT G;  5F96 G;  2NY1 A; 
#chains in the Genus database with same CATH homology
 2NXY A;  4DKV A;  4S1Q G;  4S1S G;  2NY3 A;  4H8W G;  5FA2 A;  4RFN A;  4XNY G;  4LSU G;  4XVS G;  3NGB A;  2NY2 A;  4DKP A;  4XMP G;  4OM0 G;  4RFO G;  4DVR G;  5KJR G;  5TE7 G;  3TGT A;  5TE6 G;  4JZW A;  2BF1 A;  5CD5 A;  4JPV G;  2I5Y G;  5FEC C;  5F4P A;  5F9O G;  4R4F A;  4LSS G;  2NY5 G;  4JKP G;  5CAY G;  4S1R G;  4DKU A;  4LSQ G;  4OM1 G;  4JPW G;  4I54 A;  5F4U A;  2NY4 A;  2I60 G;  3JWD A;  5F4L A;  3U7Y G;  4OLX G;  4LSR G;  3TGQ A;  4KA2 A;  4YDK G;  2QAD A;  2NY7 G;  2NXZ A;  4RX4 E;  4LSP G;  4DKO A;  4OLV G;  3HI1 G;  4P9H G;  3IDY A;  3FUS A;  5T33 G;  4DVW A;  3LQA G;  4JB9 G;  4DVS A;  4YDL A;  1RZK G;  4YDJ G;  4JM2 E;  4DKR A;  5F4R A;  4DKQ A;  4I53 A;  1YYM G;  3TGS A;  4JZZ A;  4OLU G;  4XNZ A;  4LST G;  4XVT G;  4RWY A;  1G9M G;  2NY0 A;  4LAJ A;  4RZ8 A;  4DVT A;  4DVX A;  4J6R G;  4R4N A;  3TIH A;  2B4C G;  5TE4 G;  4YFL E;  3SE8 G;  4K0A A;  4OLZ G;  4YDI G;  5IGX G;  3RJQ A;  4YE4 G;  4OLW G;  1YYL G;  1RZJ G;  4LSV G;  1GC1 G;  4OLY G;  3TGR A;  5I9Q A;  3IDX G;  1G9N G;  2NY6 A;  5F9W A;  3JWO A;  4DVV A;  4R2G A;  3SE9 G;  4JDT G;  5F96 G;  2NY1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...