5F4RA

Hiv-1 gp120 complex with bnw-iv-147
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
349
structure length
335
Chain Sequence
KTTLFCASDAKAYEKEVHNVWATHACVPTDPNPQEMVLANVTENFNMWKNDMVEQMHEDIISLWDESLKPCVKLTGGSAITQACPKVSFDPIPLHYCAPAGFAILKCNNKTFNGTGPCRNVSTVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNESVNIVCTRPNNIRQAHCNINESKWNNTLQKVGEELAKHFPSKTIKFEPSSGGDLEITTHSFNCRGEFFYCNTSDLFNGTYRNGTYNHTGRSSNGTITLQCKIKQIINMWQEVGRAIYAPPIEGEITCNSNITGLLLLRDDTETFRPGGGDMRDNWRSELYKYKVVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition.
pubmed doi rcsb
molecule tags Viral protein
source organism Human immunodeficiency virus 1
molecule keywords ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C
total genus 80
structure length 335
sequence length 349
chains with identical sequence C
ec nomenclature
pdb deposition date 2015-12-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 5f4rA01
4LSTG 2I5YG 5F4LA 5CD5A 4YDIG 2NY4A 4XMPG 3FUSA 2NXYA 4S1RG 4OLVG 4LAJA 5FA2A 4OM0G 2QADA 4DKRA 4XVSG 3TGRA 3NGBA 4RFOG 4H8WG 4OLYG 4OLUG 4DKPA 4I53A 2NXZA 4OM1G 2NY1A 2I60G 4JZWA 4R4NA 4RWYA 3JWDA 4K0AA 4XNYG 4OLZG 4DVWA 4OLXG 3LQAG 4JZZA 4S1SG 4DKVA 3TGSA 2NY7G 4XVTG 5TE6G 4XNZA 4RZ8A 5CAYG 4DKOA 3TGTA 5T33G 1YYMG 5F4RA 2NY0A 3TGQA 1RZKG 4LSUG 3IDXG 4DVTA 2B4CG 4LSQG 4RFNA 2NY5G 5F4UA 4I54A 4JKPG 4JPWG 4YDLA 4R2GA 4YE4G 5F9WA 2NY6A 4YFLE 4DKQA 5TE4G 4OLWG 4YDJG 4JDTG 3SE9G 4JB9G 4DVVA 2NY2A 3HI1G 1G9MG 5F4PA 3SE8G 4R4FA 1YYLG 3IDYA 5FECC 3RJQA 4DVSA 4LSVG 3TIHA 5I9QA 3JWOA 4DVXA 4LSSG 4DKUA 4J6RG 1G9NG 2BF1A 2NY3A 5KJRG 4P9HG 4S1QG 5F9OG 4JM2E 4KA2A 4LSRG 1RZJG 4YDKG 3U7YG 1GC1G 5TE7G 4DVRG 4LSPG 5IGXG 5F96G 4JPVG 4RX4E
chains in the Genus database with same CATH superfamily
4LSTG 2I5YG 5F4LA 5CD5A 4YDIG 2NY4A 4XMPG 3FUSA 2NXYA 4S1RG 4OLVG 4LAJA 5FA2A 4OM0G 2QADA 4DKRA 4XVSG 3TGRA 3NGBA 4RFOG 4H8WG 4OLYG 4OLUG 4DKPA 4I53A 2NXZA 4OM1G 2NY1A 2I60G 4JZWA 4R4NA 4RWYA 3JWDA 4K0AA 4XNYG 4OLZG 4DVWA 4OLXG 3LQAG 4JZZA 4S1SG 4DKVA 3TGSA 2NY7G 4XVTG 5TE6G 4XNZA 4RZ8A 5CAYG 4DKOA 3TGTA 5T33G 1YYMG 5F4RA 2NY0A 3TGQA 1RZKG 4LSUG 3IDXG 4DVTA 2B4CG 4LSQG 4RFNA 2NY5G 5F4UA 4I54A 4JKPG 4JPWG 4YDLA 4R2GA 4YE4G 5F9WA 2NY6A 4YFLE 4DKQA 5TE4G 4OLWG 4YDJG 4JDTG 3SE9G 4JB9G 4DVVA 2NY2A 3HI1G 1G9MG 5F4PA 3SE8G 4R4FA 1YYLG 3IDYA 5FECC 3RJQA 4DVSA 4LSVG 3TIHA 5I9QA 3JWOA 4DVXA 4LSSG 4DKUA 4J6RG 1G9NG 2BF1A 2NY3A 5KJRG 4P9HG 4S1QG 5F9OG 4JM2E 4KA2A 4LSRG 1RZJG 4YDKG 3U7YG 1GC1G 5TE7G 4DVRG 4LSPG 5IGXG 5F96G 4JPVG 4RX4E
chains in the Genus database with same CATH topology
4LSTG 2I5YG 5F4LA 5CD5A 4YDIG 2NY4A 4XMPG 3FUSA 2NXYA 4S1RG 4OLVG 4LAJA 5FA2A 4OM0G 2QADA 4DKRA 4XVSG 3TGRA 3NGBA 4RFOG 4H8WG 4OLYG 4OLUG 4DKPA 4I53A 2NXZA 4OM1G 2NY1A 2I60G 4JZWA 4R4NA 4RWYA 3JWDA 4K0AA 4XNYG 4OLZG 4DVWA 4OLXG 3LQAG 4JZZA 4S1SG 4DKVA 3TGSA 2NY7G 4XVTG 5TE6G 4XNZA 4RZ8A 5CAYG 4DKOA 3TGTA 5T33G 1YYMG 5F4RA 2NY0A 3TGQA 1RZKG 4LSUG 3IDXG 4DVTA 2B4CG 4LSQG 4RFNA 2NY5G 5F4UA 4I54A 4JKPG 4JPWG 4YDLA 4R2GA 4YE4G 5F9WA 2NY6A 4YFLE 4DKQA 5TE4G 4OLWG 4YDJG 4JDTG 3SE9G 4JB9G 4DVVA 2NY2A 3HI1G 1G9MG 5F4PA 3SE8G 4R4FA 1YYLG 3IDYA 5FECC 3RJQA 4DVSA 4LSVG 3TIHA 5I9QA 3JWOA 4DVXA 4LSSG 4DKUA 4J6RG 1G9NG 2BF1A 2NY3A 5KJRG 4P9HG 4S1QG 5F9OG 4JM2E 4KA2A 4LSRG 1RZJG 4YDKG 3U7YG 1GC1G 5TE7G 4DVRG 4LSPG 5IGXG 5F96G 4JPVG 4RX4E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LST G;  2I5Y G;  5F4L A;  5CD5 A;  4YDI G;  2NY4 A;  4XMP G;  3FUS A;  2NXY A;  4S1R G;  4OLV G;  4LAJ A;  5FA2 A;  4OM0 G;  2QAD A;  4DKR A;  4XVS G;  3TGR A;  3NGB A;  4RFO G;  4H8W G;  4OLY G;  4OLU G;  4DKP A;  4I53 A;  2NXZ A;  4OM1 G;  2NY1 A;  2I60 G;  4JZW A;  4R4N A;  4RWY A;  3JWD A;  4K0A A;  4XNY G;  4OLZ G;  4DVW A;  4OLX G;  3LQA G;  4JZZ A;  4S1S G;  4DKV A;  3TGS A;  2NY7 G;  4XVT G;  5TE6 G;  4XNZ A;  4RZ8 A;  5CAY G;  4DKO A;  3TGT A;  5T33 G;  1YYM G;  5F4R A;  2NY0 A;  3TGQ A;  1RZK G;  4LSU G;  3IDX G;  4DVT A;  2B4C G;  4LSQ G;  4RFN A;  2NY5 G;  5F4U A;  4I54 A;  4JKP G;  4JPW G;  4YDL A;  4R2G A;  4YE4 G;  5F9W A;  2NY6 A;  4YFL E;  4DKQ A;  5TE4 G;  4OLW G;  4YDJ G;  4JDT G;  3SE9 G;  4JB9 G;  4DVV A;  2NY2 A;  3HI1 G;  1G9M G;  5F4P A;  3SE8 G;  4R4F A;  1YYL G;  3IDY A;  5FEC C;  3RJQ A;  4DVS A;  4LSV G;  3TIH A;  5I9Q A;  3JWO A;  4DVX A;  4LSS G;  4DKU A;  4J6R G;  1G9N G;  2BF1 A;  2NY3 A;  5KJR G;  4P9H G;  4S1Q G;  5F9O G;  4JM2 E;  4KA2 A;  4LSR G;  1RZJ G;  4YDK G;  3U7Y G;  1GC1 G;  5TE7 G;  4DVR G;  4LSP G;  5IGX G;  5F96 G;  4JPV G;  4RX4 E; 
#chains in the Genus database with same CATH topology
 4LST G;  2I5Y G;  5F4L A;  5CD5 A;  4YDI G;  2NY4 A;  4XMP G;  3FUS A;  2NXY A;  4S1R G;  4OLV G;  4LAJ A;  5FA2 A;  4OM0 G;  2QAD A;  4DKR A;  4XVS G;  3TGR A;  3NGB A;  4RFO G;  4H8W G;  4OLY G;  4OLU G;  4DKP A;  4I53 A;  2NXZ A;  4OM1 G;  2NY1 A;  2I60 G;  4JZW A;  4R4N A;  4RWY A;  3JWD A;  4K0A A;  4XNY G;  4OLZ G;  4DVW A;  4OLX G;  3LQA G;  4JZZ A;  4S1S G;  4DKV A;  3TGS A;  2NY7 G;  4XVT G;  5TE6 G;  4XNZ A;  4RZ8 A;  5CAY G;  4DKO A;  3TGT A;  5T33 G;  1YYM G;  5F4R A;  2NY0 A;  3TGQ A;  1RZK G;  4LSU G;  3IDX G;  4DVT A;  2B4C G;  4LSQ G;  4RFN A;  2NY5 G;  5F4U A;  4I54 A;  4JKP G;  4JPW G;  4YDL A;  4R2G A;  4YE4 G;  5F9W A;  2NY6 A;  4YFL E;  4DKQ A;  5TE4 G;  4OLW G;  4YDJ G;  4JDT G;  3SE9 G;  4JB9 G;  4DVV A;  2NY2 A;  3HI1 G;  1G9M G;  5F4P A;  3SE8 G;  4R4F A;  1YYL G;  3IDY A;  5FEC C;  3RJQ A;  4DVS A;  4LSV G;  3TIH A;  5I9Q A;  3JWO A;  4DVX A;  4LSS G;  4DKU A;  4J6R G;  1G9N G;  2BF1 A;  2NY3 A;  5KJR G;  4P9H G;  4S1Q G;  5F9O G;  4JM2 E;  4KA2 A;  4LSR G;  1RZJ G;  4YDK G;  3U7Y G;  1GC1 G;  5TE7 G;  4DVR G;  4LSP G;  5IGX G;  5F96 G;  4JPV G;  4RX4 E; 
#chains in the Genus database with same CATH homology
 4LST G;  2I5Y G;  5F4L A;  5CD5 A;  4YDI G;  2NY4 A;  4XMP G;  3FUS A;  2NXY A;  4S1R G;  4OLV G;  4LAJ A;  5FA2 A;  4OM0 G;  2QAD A;  4DKR A;  4XVS G;  3TGR A;  3NGB A;  4RFO G;  4H8W G;  4OLY G;  4OLU G;  4DKP A;  4I53 A;  2NXZ A;  4OM1 G;  2NY1 A;  2I60 G;  4JZW A;  4R4N A;  4RWY A;  3JWD A;  4K0A A;  4XNY G;  4OLZ G;  4DVW A;  4OLX G;  3LQA G;  4JZZ A;  4S1S G;  4DKV A;  3TGS A;  2NY7 G;  4XVT G;  5TE6 G;  4XNZ A;  4RZ8 A;  5CAY G;  4DKO A;  3TGT A;  5T33 G;  1YYM G;  5F4R A;  2NY0 A;  3TGQ A;  1RZK G;  4LSU G;  3IDX G;  4DVT A;  2B4C G;  4LSQ G;  4RFN A;  2NY5 G;  5F4U A;  4I54 A;  4JKP G;  4JPW G;  4YDL A;  4R2G A;  4YE4 G;  5F9W A;  2NY6 A;  4YFL E;  4DKQ A;  5TE4 G;  4OLW G;  4YDJ G;  4JDT G;  3SE9 G;  4JB9 G;  4DVV A;  2NY2 A;  3HI1 G;  1G9M G;  5F4P A;  3SE8 G;  4R4F A;  1YYL G;  3IDY A;  5FEC C;  3RJQ A;  4DVS A;  4LSV G;  3TIH A;  5I9Q A;  3JWO A;  4DVX A;  4LSS G;  4DKU A;  4J6R G;  1G9N G;  2BF1 A;  2NY3 A;  5KJR G;  4P9H G;  4S1Q G;  5F9O G;  4JM2 E;  4KA2 A;  4LSR G;  1RZJ G;  4YDK G;  3U7Y G;  1GC1 G;  5TE7 G;  4DVR G;  4LSP G;  5IGX G;  5F96 G;  4JPV G;  4RX4 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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