5G3NA

Discovery of a novel secreted phospholipase a2 (spla2) inhibitor.
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
127
structure length
127
Chain Sequence
ALVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRISCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRCGHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Azd2716: A Novel Secreted Phospholipase A2 (Spla2) Inhibitor for the Treatment of Coronary Artery Disease
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PHOSPHOLIPASE A2, MEMBRANE ASSOCIATED
total genus 49
structure length 127
sequence length 127
chains with identical sequence B
ec nomenclature ec 3.1.1.4: Phospholipase A(2).
pdb deposition date 2016-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00068 Phospholip_A2_1 Phospholipase A2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.90.10 Mainly Alpha Up-down Bundle Phospholipase A2 Phospholipase A2 domain 5g3nA00
1BJJA 1FV0A 1Q7AA 1ZL7A 2H8IA 3BP2A 1JQ8A 1TG1A 3JR8A 3QLMA 3U8DA 1MKSA 1VIPA 1A3FA 2PHIA 4K06A 2PB8A 1SFWA 1Y75B 3CBIA 1TP2A 2QU9A 3I3HA 3NJUA 3Q4YA 1TG4A 1IT4A 4AUPA 2FNXA 1AE7A 4QF7A 2B03A 1JQ9A 3U8HA 2QOGB 2H4CA 1PIRA 2RD4A 4HMBA 1GODA 1LWBA 1HN4A 2AZZA 1MC2A 3G8HA 1YXLA 1Q6VA 1VPIA 3L30A 4O1YA 3HSWA 1JIAA 1KP4A 1S8GA 3DIHA 2QUEA 1CLPA 1O2EA 2WG7A 1Y6PA 1DB5A 3JQ5A 4QERA 2BPPA 4QF8A 2OSNA 2OTHA 2WG8B 3GCIA 3CYLA 1LE6A 3HZDA 1OYFA 1OWSA 1PODA 4NTWC 4YZ7A 1S6BA 3U8IA 1P2PA 4E4CA 3OSHA 2OYFA 2QHDA 2ZP3A 1MG6A 3O4MA 4QMCA 2Q2JA 2BCHA 2QHEA 1POEA 1AOKB 4H0SA 1XXWA 4DBKA 1TK4A 4K09A 1PC9A 1PSJA 4G5IA 1XXSA 3U8BA 1TH6A 1M8RA 1GMZA 1MH8A 1FX9A 1OZ6A 3ELOA 1FXFA 1DB4A 1O3WA 4YU7A 2ZP5A 2QVDA 2QHWA 3G8FA 1FE5A 4BP2A 1FDKA 1KVOA 3CXIA 1FAZA 1A3DA 1LE7A 2I0UA 1VL9A 1OZYA 2PMJA 1LN8A 4DCFA 1S8IA 3I03A 2B04A 1MH2A 1KQUA 1KVYA 2PH4A 5G3NA 3I3IA 2OK9A 1Y4LA 2H4CB 1PWOA 2OQDA 2RD4B 1ZLBA 1OXRA 2DPZA 1Z76A 3BJWA 1VAPA 1TJKA 2G58A 2Q1PA 1OXLA 1ZR8A 2WG9A 1PA0A 1P7OA 1N29A 1VKQA 1PSHA 2GNSA 2AZYA 3FVJA 1JLTA 4KF3A 1BVMA 1J1AA 4NTYC 1M8SA 3FG5A 2B00A 1SV9A 1POBA 2O1NA 1IJLA 4GLDA 1SXKA 1OQSA 2DO2A 1SQZA 2PVTA 1OYFB 1KVWA 3V9MA 1OWSB 1POAA 1U73A 4NTXC 4P2PA 1S6BB 3G8GA 3UX7A 1BUNA 2B01A 1PP2L 3HZWA 1TC8A 1IT5A 1SFVA 4QEMA 3P2PA 4FGAA 3R0LD 1BP2A 2OSHA 1PISA 1XXWB 3MLMA 1Y75A 1G2XA 1KVXA 1DCYA 1CL5A 1DPYA 2BP2A 1MKVA 3FVIA 1G0ZA 2BD1A 2NOTA 1KPMA 1G4IA 3FO7A 1SV3A 2QOGA 3JQLA 1BBCA 1UNEA 1C74A 1ZYXA 1C1JA 4WTBA 2OUBA 1MH2B 1GP7A 2PWSA 1RGBA 1QLLA 3T0RA 2B17A 3JTIA 4QGDA 4HG9A 1MH7A 3VBZA 5P2PA 2B96A 1Q5TA 2OLIA 1PO8A 1ZM6A 1N28A 2ZP4A 4YV5A 1GH4A 1CEHA 1TD7A 4RFPA 2WQ5A 1MKUA 3IQ3A 1Y38A 5G3MA 1U4JA 1AYPA 1A2AA 2WG8A 1L8SA 1BK9A 2BAXA 2ARMA 1B4WA 1YXHA 1TDVA 1JLTB 1M8TA 1SKGA 2AOZA 1UMVX 1SZ8A 2OTFA 4GFYA 1FB2A 1POCA 1OQSB 1MF4A 1Y6OA 1ZWPA 1IRBA 4UY1A 1AOKA 1MKTA 4EIXA 3VC0A 2PYCA 3QNLA 3H1XA 1BPQA 1TJ9A 1S8HA 1TGMA 1PPAA 2ZBHA 1T37A
chains in the Genus database with same CATH superfamily
1BJJA 1FV0A 1Q7AA 1ZL7A 2H8IA 3BP2A 1JQ8A 1TG1A 3JR8A 3QLMA 3U8DA 1MKSA 1VIPA 1A3FA 2PHIA 4K06A 2PB8A 1SFWA 1Y75B 3CBIA 1TP2A 2QU9A 3I3HA 3NJUA 3Q4YA 1TG4A 1IT4A 4AUPA 2FNXA 1AE7A 4QF7A 2B03A 1JQ9A 3U8HA 2QOGB 2H4CA 1PIRA 2RD4A 4HMBA 1GODA 1LWBA 1HN4A 2AZZA 1MC2A 3G8HA 1YXLA 1Q6VA 1VPIA 3L30A 4O1YA 3HSWA 1JIAA 1KP4A 1S8GA 3DIHA 2QUEA 1CLPA 1O2EA 2WG7A 1Y6PA 1DB5A 3JQ5A 4QERA 2BPPA 4QF8A 2OSNA 2OTHA 2WG8B 3GCIA 3CYLA 1LE6A 3HZDA 1OYFA 1OWSA 1PODA 4NTWC 4YZ7A 1S6BA 3U8IA 1P2PA 4E4CA 3OSHA 2OYFA 2QHDA 2ZP3A 1MG6A 3O4MA 4QMCA 2Q2JA 2BCHA 2QHEA 1POEA 1AOKB 4H0SA 1XXWA 4DBKA 1TK4A 4K09A 1PC9A 1PSJA 4G5IA 1XXSA 3U8BA 1TH6A 1M8RA 1GMZA 1MH8A 1FX9A 1OZ6A 3ELOA 1FXFA 1DB4A 1O3WA 4YU7A 2ZP5A 2QVDA 2QHWA 3G8FA 1FE5A 4BP2A 1FDKA 1KVOA 3CXIA 1FAZA 1A3DA 1LE7A 2I0UA 1VL9A 1OZYA 2PMJA 1LN8A 4DCFA 1S8IA 3I03A 2B04A 1MH2A 1KQUA 1KVYA 2PH4A 5G3NA 3I3IA 2OK9A 1Y4LA 2H4CB 1PWOA 2OQDA 2RD4B 1ZLBA 1OXRA 2DPZA 1Z76A 3BJWA 1VAPA 1TJKA 2G58A 2Q1PA 1OXLA 1ZR8A 2WG9A 1PA0A 1P7OA 1N29A 1VKQA 1PSHA 2GNSA 2AZYA 3FVJA 1JLTA 4KF3A 1BVMA 1J1AA 4NTYC 1M8SA 3FG5A 2B00A 1SV9A 1POBA 2O1NA 1IJLA 4GLDA 1SXKA 1OQSA 2DO2A 1SQZA 2PVTA 1OYFB 1KVWA 3V9MA 1OWSB 1POAA 1U73A 4NTXC 4P2PA 1S6BB 3G8GA 3UX7A 1BUNA 2B01A 1PP2L 3HZWA 1TC8A 1IT5A 1SFVA 4QEMA 3P2PA 4FGAA 3R0LD 1BP2A 2OSHA 1PISA 1XXWB 3MLMA 1Y75A 1G2XA 1KVXA 1DCYA 1CL5A 1DPYA 2BP2A 1MKVA 3FVIA 1G0ZA 2BD1A 2NOTA 1KPMA 1G4IA 3FO7A 1SV3A 2QOGA 3JQLA 1BBCA 1UNEA 1C74A 1ZYXA 1C1JA 4WTBA 2OUBA 1MH2B 1GP7A 2PWSA 1RGBA 1QLLA 3T0RA 2B17A 3JTIA 4QGDA 4HG9A 1MH7A 3VBZA 5P2PA 2B96A 1Q5TA 2OLIA 1PO8A 1ZM6A 1N28A 2ZP4A 4YV5A 1GH4A 1CEHA 1TD7A 4RFPA 2WQ5A 1MKUA 3IQ3A 1Y38A 5G3MA 1U4JA 1AYPA 1A2AA 2WG8A 1L8SA 1BK9A 2BAXA 2ARMA 1B4WA 1YXHA 1TDVA 1JLTB 1M8TA 1SKGA 2AOZA 1UMVX 1SZ8A 2OTFA 4GFYA 1FB2A 1POCA 1OQSB 1MF4A 1Y6OA 1ZWPA 1IRBA 4UY1A 1AOKA 1MKTA 4EIXA 3VC0A 2PYCA 3QNLA 3H1XA 1BPQA 1TJ9A 1S8HA 1TGMA 1PPAA 2ZBHA 1T37A
chains in the Genus database with same CATH topology
1BJJA 1FV0A 1Q7AA 1ZL7A 2H8IA 3BP2A 1JQ8A 1TG1A 3JR8A 3QLMA 3U8DA 1MKSA 1VIPA 1A3FA 2PHIA 4K06A 2PB8A 1SFWA 1Y75B 3CBIA 1TP2A 2QU9A 3I3HA 3NJUA 3Q4YA 1TG4A 1IT4A 4AUPA 2FNXA 1AE7A 4QF7A 2B03A 1JQ9A 3U8HA 2QOGB 2H4CA 1PIRA 2RD4A 4HMBA 1GODA 1LWBA 1HN4A 2AZZA 1MC2A 3G8HA 1YXLA 1Q6VA 1VPIA 3L30A 4O1YA 3HSWA 1JIAA 1KP4A 1S8GA 3DIHA 2QUEA 1CLPA 1O2EA 2WG7A 1Y6PA 1DB5A 3JQ5A 4QERA 2BPPA 4QF8A 2OSNA 2OTHA 2WG8B 3GCIA 3CYLA 1LE6A 3HZDA 1OYFA 1OWSA 1PODA 4NTWC 4YZ7A 1S6BA 3U8IA 1P2PA 4E4CA 3OSHA 2OYFA 2QHDA 2ZP3A 1MG6A 3O4MA 4QMCA 2Q2JA 2BCHA 2QHEA 1POEA 1AOKB 4H0SA 1XXWA 4DBKA 1TK4A 4K09A 1PC9A 1PSJA 4G5IA 1XXSA 3U8BA 1TH6A 1M8RA 1GMZA 1MH8A 1FX9A 1OZ6A 3ELOA 1FXFA 1DB4A 1O3WA 4YU7A 2ZP5A 2QVDA 2QHWA 3G8FA 1FE5A 4BP2A 1FDKA 1KVOA 3CXIA 1FAZA 1A3DA 1LE7A 2I0UA 1VL9A 1OZYA 2PMJA 1LN8A 4DCFA 1S8IA 3I03A 2B04A 1MH2A 1KQUA 1KVYA 2PH4A 5G3NA 3I3IA 2OK9A 1Y4LA 2H4CB 1PWOA 2OQDA 2RD4B 1ZLBA 1OXRA 2DPZA 1Z76A 3BJWA 1VAPA 1TJKA 2G58A 2Q1PA 1OXLA 1ZR8A 2WG9A 1PA0A 1P7OA 1N29A 1VKQA 1PSHA 2GNSA 2AZYA 3FVJA 1JLTA 4KF3A 1BVMA 1J1AA 4NTYC 1M8SA 3FG5A 2B00A 1SV9A 1POBA 2O1NA 1IJLA 4GLDA 1SXKA 1OQSA 2DO2A 1SQZA 2PVTA 1OYFB 1KVWA 3V9MA 1OWSB 1POAA 1U73A 4NTXC 4P2PA 1S6BB 3G8GA 3UX7A 1BUNA 2B01A 1PP2L 3HZWA 1TC8A 1IT5A 1SFVA 4QEMA 3P2PA 4FGAA 3R0LD 1BP2A 2OSHA 1PISA 1XXWB 3MLMA 1Y75A 1G2XA 1KVXA 1DCYA 1CL5A 1DPYA 2BP2A 1MKVA 3FVIA 1G0ZA 2BD1A 2NOTA 1KPMA 1G4IA 3FO7A 1SV3A 2QOGA 3JQLA 1BBCA 1UNEA 1C74A 1ZYXA 1C1JA 4WTBA 2OUBA 1MH2B 1GP7A 2PWSA 1RGBA 1QLLA 3T0RA 2B17A 3JTIA 4QGDA 4HG9A 1MH7A 3VBZA 5P2PA 2B96A 1Q5TA 2OLIA 1PO8A 1ZM6A 1N28A 2ZP4A 4YV5A 1GH4A 1CEHA 1TD7A 4RFPA 2WQ5A 1MKUA 3IQ3A 1Y38A 5G3MA 1U4JA 1AYPA 1A2AA 2WG8A 1L8SA 1BK9A 2BAXA 2ARMA 1B4WA 1YXHA 1TDVA 1JLTB 1M8TA 1SKGA 2AOZA 1UMVX 1SZ8A 2OTFA 4GFYA 1FB2A 1POCA 1OQSB 1MF4A 1Y6OA 1ZWPA 1IRBA 4UY1A 1AOKA 1MKTA 4EIXA 3VC0A 2PYCA 3QNLA 3H1XA 1BPQA 1TJ9A 1S8HA 1TGMA 1PPAA 2ZBHA 1T37A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BJJ A;  1FV0 A;  1Q7A A;  1ZL7 A;  2H8I A;  3BP2 A;  1JQ8 A;  1TG1 A;  3JR8 A;  3QLM A;  3U8D A;  1MKS A;  1VIP A;  1A3F A;  2PHI A;  4K06 A;  2PB8 A;  1SFW A;  1Y75 B;  3CBI A;  1TP2 A;  2QU9 A;  3I3H A;  3NJU A;  3Q4Y A;  1TG4 A;  1IT4 A;  4AUP A;  2FNX A;  1AE7 A;  4QF7 A;  2B03 A;  1JQ9 A;  3U8H A;  2QOG B;  2H4C A;  1PIR A;  2RD4 A;  4HMB A;  1GOD A;  1LWB A;  1HN4 A;  2AZZ A;  1MC2 A;  3G8H A;  1YXL A;  1Q6V A;  1VPI A;  3L30 A;  4O1Y A;  3HSW A;  1JIA A;  1KP4 A;  1S8G A;  3DIH A;  2QUE A;  1CLP A;  1O2E A;  2WG7 A;  1Y6P A;  1DB5 A;  3JQ5 A;  4QER A;  2BPP A;  4QF8 A;  2OSN A;  2OTH A;  2WG8 B;  3GCI A;  3CYL A;  1LE6 A;  3HZD A;  1OYF A;  1OWS A;  1POD A;  4NTW C;  4YZ7 A;  1S6B A;  3U8I A;  1P2P A;  4E4C A;  3OSH A;  2OYF A;  2QHD A;  2ZP3 A;  1MG6 A;  3O4M A;  4QMC A;  2Q2J A;  2BCH A;  2QHE A;  1POE A;  1AOK B;  4H0S A;  1XXW A;  4DBK A;  1TK4 A;  4K09 A;  1PC9 A;  1PSJ A;  4G5I A;  1XXS A;  3U8B A;  1TH6 A;  1M8R A;  1GMZ A;  1MH8 A;  1FX9 A;  1OZ6 A;  3ELO A;  1FXF A;  1DB4 A;  1O3W A;  4YU7 A;  2ZP5 A;  2QVD A;  2QHW A;  3G8F A;  1FE5 A;  4BP2 A;  1FDK A;  1KVO A;  3CXI A;  1FAZ A;  1A3D A;  1LE7 A;  2I0U A;  1VL9 A;  1OZY A;  2PMJ A;  1LN8 A;  4DCF A;  1S8I A;  3I03 A;  2B04 A;  1MH2 A;  1KQU A;  1KVY A;  2PH4 A;  5G3N A;  3I3I A;  2OK9 A;  1Y4L A;  2H4C B;  1PWO A;  2OQD A;  2RD4 B;  1ZLB A;  1OXR A;  2DPZ A;  1Z76 A;  3BJW A;  1VAP A;  1TJK A;  2G58 A;  2Q1P A;  1OXL A;  1ZR8 A;  2WG9 A;  1PA0 A;  1P7O A;  1N29 A;  1VKQ A;  1PSH A;  2GNS A;  2AZY A;  3FVJ A;  1JLT A;  4KF3 A;  1BVM A;  1J1A A;  4NTY C;  1M8S A;  3FG5 A;  2B00 A;  1SV9 A;  1POB A;  2O1N A;  1IJL A;  4GLD A;  1SXK A;  1OQS A;  2DO2 A;  1SQZ A;  2PVT A;  1OYF B;  1KVW A;  3V9M A;  1OWS B;  1POA A;  1U73 A;  4NTX C;  4P2P A;  1S6B B;  3G8G A;  3UX7 A;  1BUN A;  2B01 A;  1PP2 L;  3HZW A;  1TC8 A;  1IT5 A;  1SFV A;  4QEM A;  3P2P A;  4FGA A;  3R0L D;  1BP2 A;  2OSH A;  1PIS A;  1XXW B;  3MLM A;  1Y75 A;  1G2X A;  1KVX A;  1DCY A;  1CL5 A;  1DPY A;  2BP2 A;  1MKV A;  3FVI A;  1G0Z A;  2BD1 A;  2NOT A;  1KPM A;  1G4I A;  3FO7 A;  1SV3 A;  2QOG A;  3JQL A;  1BBC A;  1UNE A;  1C74 A;  1ZYX A;  1C1J A;  4WTB A;  2OUB A;  1MH2 B;  1GP7 A;  2PWS A;  1RGB A;  1QLL A;  3T0R A;  2B17 A;  3JTI A;  4QGD A;  4HG9 A;  1MH7 A;  3VBZ A;  5P2P A;  2B96 A;  1Q5T A;  2OLI A;  1PO8 A;  1ZM6 A;  1N28 A;  2ZP4 A;  4YV5 A;  1GH4 A;  1CEH A;  1TD7 A;  4RFP A;  2WQ5 A;  1MKU A;  3IQ3 A;  1Y38 A;  5G3M A;  1U4J A;  1AYP A;  1A2A A;  2WG8 A;  1L8S A;  1BK9 A;  2BAX A;  2ARM A;  1B4W A;  1YXH A;  1TDV A;  1JLT B;  1M8T A;  1SKG A;  2AOZ A;  1UMV X;  1SZ8 A;  2OTF A;  4GFY A;  1FB2 A;  1POC A;  1OQS B;  1MF4 A;  1Y6O A;  1ZWP A;  1IRB A;  4UY1 A;  1AOK A;  1MKT A;  4EIX A;  3VC0 A;  2PYC A;  3QNL A;  3H1X A;  1BPQ A;  1TJ9 A;  1S8H A;  1TGM A;  1PPA A;  2ZBH A;  1T37 A; 
#chains in the Genus database with same CATH topology
 1BJJ A;  1FV0 A;  1Q7A A;  1ZL7 A;  2H8I A;  3BP2 A;  1JQ8 A;  1TG1 A;  3JR8 A;  3QLM A;  3U8D A;  1MKS A;  1VIP A;  1A3F A;  2PHI A;  4K06 A;  2PB8 A;  1SFW A;  1Y75 B;  3CBI A;  1TP2 A;  2QU9 A;  3I3H A;  3NJU A;  3Q4Y A;  1TG4 A;  1IT4 A;  4AUP A;  2FNX A;  1AE7 A;  4QF7 A;  2B03 A;  1JQ9 A;  3U8H A;  2QOG B;  2H4C A;  1PIR A;  2RD4 A;  4HMB A;  1GOD A;  1LWB A;  1HN4 A;  2AZZ A;  1MC2 A;  3G8H A;  1YXL A;  1Q6V A;  1VPI A;  3L30 A;  4O1Y A;  3HSW A;  1JIA A;  1KP4 A;  1S8G A;  3DIH A;  2QUE A;  1CLP A;  1O2E A;  2WG7 A;  1Y6P A;  1DB5 A;  3JQ5 A;  4QER A;  2BPP A;  4QF8 A;  2OSN A;  2OTH A;  2WG8 B;  3GCI A;  3CYL A;  1LE6 A;  3HZD A;  1OYF A;  1OWS A;  1POD A;  4NTW C;  4YZ7 A;  1S6B A;  3U8I A;  1P2P A;  4E4C A;  3OSH A;  2OYF A;  2QHD A;  2ZP3 A;  1MG6 A;  3O4M A;  4QMC A;  2Q2J A;  2BCH A;  2QHE A;  1POE A;  1AOK B;  4H0S A;  1XXW A;  4DBK A;  1TK4 A;  4K09 A;  1PC9 A;  1PSJ A;  4G5I A;  1XXS A;  3U8B A;  1TH6 A;  1M8R A;  1GMZ A;  1MH8 A;  1FX9 A;  1OZ6 A;  3ELO A;  1FXF A;  1DB4 A;  1O3W A;  4YU7 A;  2ZP5 A;  2QVD A;  2QHW A;  3G8F A;  1FE5 A;  4BP2 A;  1FDK A;  1KVO A;  3CXI A;  1FAZ A;  1A3D A;  1LE7 A;  2I0U A;  1VL9 A;  1OZY A;  2PMJ A;  1LN8 A;  4DCF A;  1S8I A;  3I03 A;  2B04 A;  1MH2 A;  1KQU A;  1KVY A;  2PH4 A;  5G3N A;  3I3I A;  2OK9 A;  1Y4L A;  2H4C B;  1PWO A;  2OQD A;  2RD4 B;  1ZLB A;  1OXR A;  2DPZ A;  1Z76 A;  3BJW A;  1VAP A;  1TJK A;  2G58 A;  2Q1P A;  1OXL A;  1ZR8 A;  2WG9 A;  1PA0 A;  1P7O A;  1N29 A;  1VKQ A;  1PSH A;  2GNS A;  2AZY A;  3FVJ A;  1JLT A;  4KF3 A;  1BVM A;  1J1A A;  4NTY C;  1M8S A;  3FG5 A;  2B00 A;  1SV9 A;  1POB A;  2O1N A;  1IJL A;  4GLD A;  1SXK A;  1OQS A;  2DO2 A;  1SQZ A;  2PVT A;  1OYF B;  1KVW A;  3V9M A;  1OWS B;  1POA A;  1U73 A;  4NTX C;  4P2P A;  1S6B B;  3G8G A;  3UX7 A;  1BUN A;  2B01 A;  1PP2 L;  3HZW A;  1TC8 A;  1IT5 A;  1SFV A;  4QEM A;  3P2P A;  4FGA A;  3R0L D;  1BP2 A;  2OSH A;  1PIS A;  1XXW B;  3MLM A;  1Y75 A;  1G2X A;  1KVX A;  1DCY A;  1CL5 A;  1DPY A;  2BP2 A;  1MKV A;  3FVI A;  1G0Z A;  2BD1 A;  2NOT A;  1KPM A;  1G4I A;  3FO7 A;  1SV3 A;  2QOG A;  3JQL A;  1BBC A;  1UNE A;  1C74 A;  1ZYX A;  1C1J A;  4WTB A;  2OUB A;  1MH2 B;  1GP7 A;  2PWS A;  1RGB A;  1QLL A;  3T0R A;  2B17 A;  3JTI A;  4QGD A;  4HG9 A;  1MH7 A;  3VBZ A;  5P2P A;  2B96 A;  1Q5T A;  2OLI A;  1PO8 A;  1ZM6 A;  1N28 A;  2ZP4 A;  4YV5 A;  1GH4 A;  1CEH A;  1TD7 A;  4RFP A;  2WQ5 A;  1MKU A;  3IQ3 A;  1Y38 A;  5G3M A;  1U4J A;  1AYP A;  1A2A A;  2WG8 A;  1L8S A;  1BK9 A;  2BAX A;  2ARM A;  1B4W A;  1YXH A;  1TDV A;  1JLT B;  1M8T A;  1SKG A;  2AOZ A;  1UMV X;  1SZ8 A;  2OTF A;  4GFY A;  1FB2 A;  1POC A;  1OQS B;  1MF4 A;  1Y6O A;  1ZWP A;  1IRB A;  4UY1 A;  1AOK A;  1MKT A;  4EIX A;  3VC0 A;  2PYC A;  3QNL A;  3H1X A;  1BPQ A;  1TJ9 A;  1S8H A;  1TGM A;  1PPA A;  2ZBH A;  1T37 A; 
#chains in the Genus database with same CATH homology
 1BJJ A;  1FV0 A;  1Q7A A;  1ZL7 A;  2H8I A;  3BP2 A;  1JQ8 A;  1TG1 A;  3JR8 A;  3QLM A;  3U8D A;  1MKS A;  1VIP A;  1A3F A;  2PHI A;  4K06 A;  2PB8 A;  1SFW A;  1Y75 B;  3CBI A;  1TP2 A;  2QU9 A;  3I3H A;  3NJU A;  3Q4Y A;  1TG4 A;  1IT4 A;  4AUP A;  2FNX A;  1AE7 A;  4QF7 A;  2B03 A;  1JQ9 A;  3U8H A;  2QOG B;  2H4C A;  1PIR A;  2RD4 A;  4HMB A;  1GOD A;  1LWB A;  1HN4 A;  2AZZ A;  1MC2 A;  3G8H A;  1YXL A;  1Q6V A;  1VPI A;  3L30 A;  4O1Y A;  3HSW A;  1JIA A;  1KP4 A;  1S8G A;  3DIH A;  2QUE A;  1CLP A;  1O2E A;  2WG7 A;  1Y6P A;  1DB5 A;  3JQ5 A;  4QER A;  2BPP A;  4QF8 A;  2OSN A;  2OTH A;  2WG8 B;  3GCI A;  3CYL A;  1LE6 A;  3HZD A;  1OYF A;  1OWS A;  1POD A;  4NTW C;  4YZ7 A;  1S6B A;  3U8I A;  1P2P A;  4E4C A;  3OSH A;  2OYF A;  2QHD A;  2ZP3 A;  1MG6 A;  3O4M A;  4QMC A;  2Q2J A;  2BCH A;  2QHE A;  1POE A;  1AOK B;  4H0S A;  1XXW A;  4DBK A;  1TK4 A;  4K09 A;  1PC9 A;  1PSJ A;  4G5I A;  1XXS A;  3U8B A;  1TH6 A;  1M8R A;  1GMZ A;  1MH8 A;  1FX9 A;  1OZ6 A;  3ELO A;  1FXF A;  1DB4 A;  1O3W A;  4YU7 A;  2ZP5 A;  2QVD A;  2QHW A;  3G8F A;  1FE5 A;  4BP2 A;  1FDK A;  1KVO A;  3CXI A;  1FAZ A;  1A3D A;  1LE7 A;  2I0U A;  1VL9 A;  1OZY A;  2PMJ A;  1LN8 A;  4DCF A;  1S8I A;  3I03 A;  2B04 A;  1MH2 A;  1KQU A;  1KVY A;  2PH4 A;  5G3N A;  3I3I A;  2OK9 A;  1Y4L A;  2H4C B;  1PWO A;  2OQD A;  2RD4 B;  1ZLB A;  1OXR A;  2DPZ A;  1Z76 A;  3BJW A;  1VAP A;  1TJK A;  2G58 A;  2Q1P A;  1OXL A;  1ZR8 A;  2WG9 A;  1PA0 A;  1P7O A;  1N29 A;  1VKQ A;  1PSH A;  2GNS A;  2AZY A;  3FVJ A;  1JLT A;  4KF3 A;  1BVM A;  1J1A A;  4NTY C;  1M8S A;  3FG5 A;  2B00 A;  1SV9 A;  1POB A;  2O1N A;  1IJL A;  4GLD A;  1SXK A;  1OQS A;  2DO2 A;  1SQZ A;  2PVT A;  1OYF B;  1KVW A;  3V9M A;  1OWS B;  1POA A;  1U73 A;  4NTX C;  4P2P A;  1S6B B;  3G8G A;  3UX7 A;  1BUN A;  2B01 A;  1PP2 L;  3HZW A;  1TC8 A;  1IT5 A;  1SFV A;  4QEM A;  3P2P A;  4FGA A;  3R0L D;  1BP2 A;  2OSH A;  1PIS A;  1XXW B;  3MLM A;  1Y75 A;  1G2X A;  1KVX A;  1DCY A;  1CL5 A;  1DPY A;  2BP2 A;  1MKV A;  3FVI A;  1G0Z A;  2BD1 A;  2NOT A;  1KPM A;  1G4I A;  3FO7 A;  1SV3 A;  2QOG A;  3JQL A;  1BBC A;  1UNE A;  1C74 A;  1ZYX A;  1C1J A;  4WTB A;  2OUB A;  1MH2 B;  1GP7 A;  2PWS A;  1RGB A;  1QLL A;  3T0R A;  2B17 A;  3JTI A;  4QGD A;  4HG9 A;  1MH7 A;  3VBZ A;  5P2P A;  2B96 A;  1Q5T A;  2OLI A;  1PO8 A;  1ZM6 A;  1N28 A;  2ZP4 A;  4YV5 A;  1GH4 A;  1CEH A;  1TD7 A;  4RFP A;  2WQ5 A;  1MKU A;  3IQ3 A;  1Y38 A;  5G3M A;  1U4J A;  1AYP A;  1A2A A;  2WG8 A;  1L8S A;  1BK9 A;  2BAX A;  2ARM A;  1B4W A;  1YXH A;  1TDV A;  1JLT B;  1M8T A;  1SKG A;  2AOZ A;  1UMV X;  1SZ8 A;  2OTF A;  4GFY A;  1FB2 A;  1POC A;  1OQS B;  1MF4 A;  1Y6O A;  1ZWP A;  1IRB A;  4UY1 A;  1AOK A;  1MKT A;  4EIX A;  3VC0 A;  2PYC A;  3QNL A;  3H1X A;  1BPQ A;  1TJ9 A;  1S8H A;  1TGM A;  1PPA A;  2ZBH A;  1T37 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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