5GW6A

Water-bridge mediates recognition of mrna cap in eif4e
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
186
structure length
182
Chain Sequence
EHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDAANARGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKTKNRFVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Water-Bridge Mediates Recognition of mRNA Cap in eIF4E
pubmed doi rcsb
molecule tags Translation
source organism Homo sapiens
molecule keywords Eukaryotic translation initiation factor 4E
total genus 57
structure length 182
sequence length 186
ec nomenclature
pdb deposition date 2016-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01652 IF4E Eukaryotic initiation factor 4E
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.760.10 Alpha Beta 2-Layer Sandwich RNA Cap, Translation Initiation Factor Eif4e RNA Cap, Translation Initiation Factor Eif4e 5gw6A00
1ZTPA 5GW6A 2WMCA 2Q4KA 5T48A 2W97B 2W97A 3M94A 5EIRA 5ABYA 3HXIA 5EI3A 5EKVA 3AM7A 1EJ1A 1IPBA 4UECA 2JGBA 4AZAA 1AP8A 1IPCA 5ABXA 2JGCA 2V8YA 3M93A 2IDRA 4UE8A 4B6UA 1RF8A 4UEDA 5BXVA 3HXGA 2V8XA 3U7XA 1EJHA 1EJ4A 5T46A 4UEBA 5EHCA 4UEAA 4DUMA 4UE9A 1L8BA 2V8WA 4TPWA 3TF2A 2IDVA 4BEAA 1WKWA 4AXGA 2GPQA 4DT6A 5ABVA 4B6VA 4TQCA 5ABUA 4TQBA 5T47A
chains in the Genus database with same CATH superfamily
1ZTPA 5GW6A 2WMCA 2Q4KA 5T48A 2W97B 2W97A 3M94A 5EIRA 5ABYA 3HXIA 5EI3A 5EKVA 3AM7A 1EJ1A 1IPBA 4UECA 2JGBA 4AZAA 1AP8A 1IPCA 5ABXA 2JGCA 2V8YA 3M93A 2IDRA 4UE8A 4B6UA 1RF8A 4UEDA 5BXVA 3HXGA 2V8XA 3U7XA 1EJHA 1EJ4A 5T46A 4UEBA 5EHCA 4UEAA 4DUMA 4UE9A 1L8BA 2V8WA 4TPWA 3TF2A 2IDVA 4BEAA 1WKWA 4AXGA 2GPQA 4DT6A 5ABVA 4B6VA 4TQCA 5ABUA 4TQBA 5T47A
chains in the Genus database with same CATH topology
1ZTPA 5GW6A 2WMCA 2Q4KA 5T48A 2W97B 2W97A 3M94A 5EIRA 5ABYA 3HXIA 5EI3A 5EKVA 3AM7A 1EJ1A 1IPBA 4UECA 2JGBA 4AZAA 1AP8A 1IPCA 5ABXA 2JGCA 2V8YA 3M93A 2IDRA 4UE8A 4B6UA 1RF8A 4UEDA 5BXVA 3HXGA 2V8XA 3U7XA 1EJHA 1EJ4A 5T46A 4UEBA 5EHCA 4UEAA 4DUMA 4UE9A 1L8BA 2V8WA 4TPWA 3TF2A 2IDVA 4BEAA 1WKWA 4AXGA 2GPQA 4DT6A 5ABVA 4B6VA 4TQCA 5ABUA 4TQBA 5T47A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZTP A;  5GW6 A;  2WMC A;  2Q4K A;  5T48 A;  2W97 B;  2W97 A;  3M94 A;  5EIR A;  5ABY A;  3HXI A;  5EI3 A;  5EKV A;  3AM7 A;  1EJ1 A;  1IPB A;  4UEC A;  2JGB A;  4AZA A;  1AP8 A;  1IPC A;  5ABX A;  2JGC A;  2V8Y A;  3M93 A;  2IDR A;  4UE8 A;  4B6U A;  1RF8 A;  4UED A;  5BXV A;  3HXG A;  2V8X A;  3U7X A;  1EJH A;  1EJ4 A;  5T46 A;  4UEB A;  5EHC A;  4UEA A;  4DUM A;  4UE9 A;  1L8B A;  2V8W A;  4TPW A;  3TF2 A;  2IDV A;  4BEA A;  1WKW A;  4AXG A;  2GPQ A;  4DT6 A;  5ABV A;  4B6V A;  4TQC A;  5ABU A;  4TQB A;  5T47 A; 
#chains in the Genus database with same CATH topology
 1ZTP A;  5GW6 A;  2WMC A;  2Q4K A;  5T48 A;  2W97 B;  2W97 A;  3M94 A;  5EIR A;  5ABY A;  3HXI A;  5EI3 A;  5EKV A;  3AM7 A;  1EJ1 A;  1IPB A;  4UEC A;  2JGB A;  4AZA A;  1AP8 A;  1IPC A;  5ABX A;  2JGC A;  2V8Y A;  3M93 A;  2IDR A;  4UE8 A;  4B6U A;  1RF8 A;  4UED A;  5BXV A;  3HXG A;  2V8X A;  3U7X A;  1EJH A;  1EJ4 A;  5T46 A;  4UEB A;  5EHC A;  4UEA A;  4DUM A;  4UE9 A;  1L8B A;  2V8W A;  4TPW A;  3TF2 A;  2IDV A;  4BEA A;  1WKW A;  4AXG A;  2GPQ A;  4DT6 A;  5ABV A;  4B6V A;  4TQC A;  5ABU A;  4TQB A;  5T47 A; 
#chains in the Genus database with same CATH homology
 1ZTP A;  5GW6 A;  2WMC A;  2Q4K A;  5T48 A;  2W97 B;  2W97 A;  3M94 A;  5EIR A;  5ABY A;  3HXI A;  5EI3 A;  5EKV A;  3AM7 A;  1EJ1 A;  1IPB A;  4UEC A;  2JGB A;  4AZA A;  1AP8 A;  1IPC A;  5ABX A;  2JGC A;  2V8Y A;  3M93 A;  2IDR A;  4UE8 A;  4B6U A;  1RF8 A;  4UED A;  5BXV A;  3HXG A;  2V8X A;  3U7X A;  1EJH A;  1EJ4 A;  5T46 A;  4UEB A;  5EHC A;  4UEA A;  4DUM A;  4UE9 A;  1L8B A;  2V8W A;  4TPW A;  3TF2 A;  2IDV A;  4BEA A;  1WKW A;  4AXG A;  2GPQ A;  4DT6 A;  5ABV A;  4B6V A;  4TQC A;  5ABU A;  4TQB A;  5T47 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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