5HQ0C

Ternary complex of human proteins cdk1, cyclin b and cks2, bound to an inhibitor
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
74
structure length
74
Chain Sequence
MAHKQIYYSDKYFDEHYEYRHVMLPRELSKQVPKTHLMSEEEWRRLGVQQSLGWVHYMIHEPEPHILLFRRPLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title CDK1 structures reveal conserved and unique features of the essential cell cycle CDK.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Cyclin-dependent kinase 1
total genus 11
structure length 74
sequence length 74
ec nomenclature
pdb deposition date 2016-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01111 CKS Cyclin-dependent kinase regulatory subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.170.10 Alpha Beta 2-Layer Sandwich Cyclin-Dependent Kinase Subunit Type 2 Cyclin-dependent kinase, regulatory subunit 5hq0C00
4LPAA 2ASTC 4YC6B 5HQ0C 1SCEA 4Y72C 1PUCA 1CKSA 1QB3A 2ASSC 3QY2A 5LQFC 1BUHB 1DKSA 4YC3C 1DKTA
chains in the Genus database with same CATH superfamily
4LPAA 2ASTC 4YC6B 5HQ0C 1SCEA 4Y72C 1PUCA 1CKSA 1QB3A 2ASSC 3QY2A 5LQFC 1BUHB 1DKSA 4YC3C 1DKTA
chains in the Genus database with same CATH topology
4LPAA 2ASTC 4YC6B 5HQ0C 1SCEA 4Y72C 1PUCA 1CKSA 1QB3A 2ASSC 3QY2A 5LQFC 1BUHB 1DKSA 4YC3C 1DKTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LPA A;  2AST C;  4YC6 B;  5HQ0 C;  1SCE A;  4Y72 C;  1PUC A;  1CKS A;  1QB3 A;  2ASS C;  3QY2 A;  5LQF C;  1BUH B;  1DKS A;  4YC3 C;  1DKT A; 
#chains in the Genus database with same CATH topology
 4LPA A;  2AST C;  4YC6 B;  5HQ0 C;  1SCE A;  4Y72 C;  1PUC A;  1CKS A;  1QB3 A;  2ASS C;  3QY2 A;  5LQF C;  1BUH B;  1DKS A;  4YC3 C;  1DKT A; 
#chains in the Genus database with same CATH homology
 4LPA A;  2AST C;  4YC6 B;  5HQ0 C;  1SCE A;  4Y72 C;  1PUC A;  1CKS A;  1QB3 A;  2ASS C;  3QY2 A;  5LQF C;  1BUH B;  1DKS A;  4YC3 C;  1DKT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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